Compile Data Set for Download or QSAR

Found 452 hits with Last Name = 'moszczy?ski-p?tkowski' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50048803 (5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...) Show SMILES Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	0.851	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-methylspiperone from human D2 long receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50048803 (5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...) Show SMILES Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-methylspiperone from human D2 long receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50318633 (3-benzenesulfonyl-8-piperazin-1-ylquinoline | CHEM...) Show SMILES O=S(=O)(c1ccccc1)c1cnc2c(cccc2c1)N1CCNCC1 Show InChI InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6R expressed in HEK293 cell membranes after 1 hr				Bioorg Med Chem 26: 3588-3595 (2018) Article DOI: 10.1016/j.bmc.2018.05.033 BindingDB Entry DOI: 10.7270/Q2BC4219
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504838 (CHEMBL4437523) Show SMILES Oc1ccc(cc1)-c1ccc(CNCCc2c[nH]c3ccc(F)cc23)o1 Show InChI InChI=1S/C21H19FN2O2/c22-16-3-7-20-19(11-16)15(12-24-20)9-10-23-13-18-6-8-21(26-18)14-1-4-17(25)5-2-14/h1-8,11-12,23-25H,9-10,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513415 (CHEMBL4435010) Show SMILES Cl.COc1ccc2n(cc(-c3cnc(N)[nH]3)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H16N4O3S/c1-25-12-7-8-17-14(9-12)15(16-10-20-18(19)21-16)11-22(17)26(23,24)13-5-3-2-4-6-13/h2-11H,1H3,(H3,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504839 (CHEMBL4584504) Show SMILES Oc1ccc(cc1)-c1ccc(CNCCc2c[nH]c3cc(F)ccc23)o1 Show InChI InChI=1S/C21H19FN2O2/c22-16-3-7-19-15(12-24-20(19)11-16)9-10-23-13-18-6-8-21(26-18)14-1-4-17(25)5-2-14/h1-8,11-12,23-25H,9-10,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50048803 (5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...) Show SMILES Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from human D2R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513438 (CHEMBL4574931) Show SMILES Cl.COc1ccc2n(cc(-c3[nH]c(N)nc3C)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H18N4O3S/c1-12-18(22-19(20)21-12)16-11-23(17-9-8-13(26-2)10-15(16)17)27(24,25)14-6-4-3-5-7-14/h3-11H,1-2H3,(H3,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513432 (CHEMBL4586990) Show SMILES COc1ccc2n(cc(-c3[nH]c(NC(=O)Cc4ccccc4)nc3C)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C27H24N4O4S/c1-18-26(30-27(28-18)29-25(32)15-19-9-5-3-6-10-19)23-17-31(24-14-13-20(35-2)16-22(23)24)36(33,34)21-11-7-4-8-12-21/h3-14,16-17H,15H2,1-2H3,(H2,28,29,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504842 (CHEMBL4583082) Show SMILES COc1ccc2[nH]cc(CCNCc3ccc(o3)-c3ccc(O)cc3)c2c1 Show InChI InChI=1S/C22H22N2O3/c1-26-18-6-8-21-20(12-18)16(13-24-21)10-11-23-14-19-7-9-22(27-19)15-2-4-17(25)5-3-15/h2-9,12-13,23-25H,10-11,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50274767 (CHEMBL4125735) Show SMILES Clc1cccc(c1)S(=O)(=O)n1ccc2c(N[C@H]3CCNC3)nc3ccccc3c12 |r| Show InChI InChI=1S/C21H19ClN4O2S/c22-14-4-3-5-16(12-14)29(27,28)26-11-9-18-20(26)17-6-1-2-7-19(17)25-21(18)24-15-8-10-23-13-15/h1-7,9,11-12,15,23H,8,10,13H2,(H,24,25)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6R expressed in HEK293 cell membranes after 1 hr				Bioorg Med Chem 26: 3588-3595 (2018) Article DOI: 10.1016/j.bmc.2018.05.033 BindingDB Entry DOI: 10.7270/Q2BC4219
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50019754 (IDALOPIRDINE | LU-AE58054) Show SMILES FC(F)C(F)(F)COc1cccc(CNCCc2c[nH]c3cc(F)ccc23)c1 Show InChI InChI=1S/C20H19F5N2O/c21-15-4-5-17-14(11-27-18(17)9-15)6-7-26-10-13-2-1-3-16(8-13)28-12-20(24,25)19(22)23/h1-5,8-9,11,19,26-27H,6-7,10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513435 (CHEMBL4472629) Show SMILES Cl.Cc1nc(N)[nH]c1-c1ccc2ccn(c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H16N4O2S/c1-12-17(21-18(19)20-12)14-8-7-13-9-10-22(16(13)11-14)25(23,24)15-5-3-2-4-6-15/h2-11H,1H3,(H3,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504843 (CHEMBL4438434) Show SMILES Cc1ccc2[nH]cc(CCNCc3ccc(o3)-c3ccc(O)cc3)c2c1 Show InChI InChI=1S/C22H22N2O2/c1-15-2-8-21-20(12-15)17(13-24-21)10-11-23-14-19-7-9-22(26-19)16-3-5-18(25)6-4-16/h2-9,12-13,23-25H,10-11,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHOK1 cells incubated for 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHOK1 cells incubated for 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to human 5-HT2AR expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504814 (CHEMBL4465414) Show SMILES Oc1ccc(cc1)-c1ccc(CNCCc2c[nH]c3ccccc23)o1 Show InChI InChI=1S/C21H20N2O2/c24-17-7-5-15(6-8-17)21-10-9-18(25-21)14-22-12-11-16-13-23-20-4-2-1-3-19(16)20/h1-10,13,22-24H,11-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504847 (CHEMBL4516220) Show SMILES CN1NCc2c1nc(nc2NCc1ccccc1)N1CCN(C)CC1 Show InChI InChI=1S/C18H25N7/c1-23-8-10-25(11-9-23)18-21-16(15-13-20-24(2)17(15)22-18)19-12-14-6-4-3-5-7-14/h3-7,20H,8-13H2,1-2H3,(H,19,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to 5-HT6R (unknown origin) assessed as inhibitory constant				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513431 (CHEMBL4471055) Show SMILES Cl.Cc1nc(N)[nH]c1-c1cn(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H18N4O2S/c1-14-21(25-22(23)24-14)18-13-26(19-11-5-4-10-17(18)19)29(27,28)20-12-6-8-15-7-2-3-9-16(15)20/h2-13H,1H3,(H3,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513433 (CHEMBL4465638) Show SMILES CCC(=O)Nc1nc(C)c([nH]1)-c1cn(c2ccc(OC)cc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C22H21FN4O4S/c1-4-20(28)25-22-24-13(2)21(26-22)18-12-27(19-9-8-15(31-3)11-17(18)19)32(29,30)16-7-5-6-14(23)10-16/h5-12H,4H2,1-3H3,(H2,24,25,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513417 (CHEMBL4451939) Show SMILES Cl.COc1ccc2n(cc(-c3[nH]c(N)nc3C)c2c1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C23H20N4O3S/c1-14-22(26-23(24)25-14)20-13-27(21-10-8-17(30-2)12-19(20)21)31(28,29)18-9-7-15-5-3-4-6-16(15)11-18/h3-13H,1-2H3,(H3,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513399 (CHEMBL4552168) Show SMILES Cl.COc1ccc2n(cc(-c3[nH]c(N)nc3C)c2c1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C19H17FN4O3S/c1-11-18(23-19(21)22-11)16-10-24(17-7-6-13(27-2)9-15(16)17)28(25,26)14-5-3-4-12(20)8-14/h3-10H,1-2H3,(H3,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513416 (CHEMBL4590882) Show SMILES Cl.COc1ccc2n(cc(-c3cnc(N)[nH]3)c2c1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C18H15FN4O3S/c1-26-12-5-6-17-14(8-12)15(16-9-21-18(20)22-16)10-23(17)27(24,25)13-4-2-3-11(19)7-13/h2-10H,1H3,(H3,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513436 (CHEMBL4441060) Show SMILES Cl.Nc1ncc([nH]1)-c1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H14N4O2S/c18-17-19-10-15(20-17)14-11-21(16-9-5-4-8-13(14)16)24(22,23)12-6-2-1-3-7-12/h1-11H,(H3,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513439 (CHEMBL4513458) Show SMILES CCC(=O)Nc1nc(C)c([nH]1)-c1cn(c2ccc(OC)cc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C26H24N4O4S/c1-4-24(31)28-26-27-16(2)25(29-26)21-15-30(22-13-12-18(34-3)14-20(21)22)35(32,33)23-11-7-9-17-8-5-6-10-19(17)23/h5-15H,4H2,1-3H3,(H2,27,28,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513408 (CHEMBL4469792) Show SMILES COc1ccc2n(cc(-c3[nH]c(NC(C)=O)nc3C)c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C25H22N4O4S/c1-15-24(28-25(26-15)27-16(2)30)21-14-29(22-12-11-18(33-3)13-20(21)22)34(31,32)23-10-6-8-17-7-4-5-9-19(17)23/h4-14H,1-3H3,(H2,26,27,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513402 (CHEMBL4461327) Show SMILES COc1ccc2n(cc(-c3[nH]c(NC(C)=O)nc3C)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H20N4O4S/c1-13-20(24-21(22-13)23-14(2)26)18-12-25(19-10-9-15(29-3)11-17(18)19)30(27,28)16-7-5-4-6-8-16/h4-12H,1-3H3,(H2,22,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513396 (CHEMBL4442332) Show SMILES Cl.COc1ccc2n(cc(-c3[nH]c(N)nc3C)c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H20N4O3S/c1-14-22(26-23(24)25-14)19-13-27(20-11-10-16(30-2)12-18(19)20)31(28,29)21-9-5-7-15-6-3-4-8-17(15)21/h3-13H,1-2H3,(H3,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50504838 (CHEMBL4437523) Show SMILES Oc1ccc(cc1)-c1ccc(CNCCc2c[nH]c3ccc(F)cc23)o1 Show InChI InChI=1S/C21H19FN2O2/c22-16-3-7-20-19(11-16)15(12-24-20)9-10-23-13-18-6-8-21(26-18)14-1-4-17(25)5-2-14/h1-8,11-12,23-25H,9-10,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to human 5-HT2AR expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513423 (CHEMBL4566557) Show SMILES CC(=O)Nc1nc(C)c([nH]1)-c1cn(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C24H20N4O3S/c1-15-23(27-24(25-15)26-16(2)29)20-14-28(21-12-6-5-11-19(20)21)32(30,31)22-13-7-9-17-8-3-4-10-18(17)22/h3-14H,1-2H3,(H2,25,26,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513405 (CHEMBL4521199) Show SMILES COc1ccc2n(cc(-c3[nH]c(NC(C)=O)nc3C)c2c1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C21H19FN4O4S/c1-12-20(25-21(23-12)24-13(2)27)18-11-26(19-8-7-15(30-3)10-17(18)19)31(28,29)16-6-4-5-14(22)9-16/h4-11H,1-3H3,(H2,23,24,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513397 (CHEMBL4440402) Show SMILES CCC(=O)Nc1nc(C)c([nH]1)-c1cn(c2ccc(OC)cc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C22H22N4O4S/c1-4-20(27)24-22-23-14(2)21(25-22)18-13-26(19-11-10-15(30-3)12-17(18)19)31(28,29)16-8-6-5-7-9-16/h5-13H,4H2,1-3H3,(H2,23,24,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513414 (CHEMBL4586353) Show SMILES Cl.Cc1nc(N)[nH]c1-c1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H16N4O2S/c1-12-17(21-18(19)20-12)15-11-22(16-10-6-5-9-14(15)16)25(23,24)13-7-3-2-4-8-13/h2-11H,1H3,(H3,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504816 (CHEMBL4474618) Show SMILES COc1cccc2[nH]cc(CCNCc3ccc(o3)-c3ccc(O)cc3)c12 Show InChI InChI=1S/C22H22N2O3/c1-26-21-4-2-3-19-22(21)16(13-24-19)11-12-23-14-18-9-10-20(27-18)15-5-7-17(25)8-6-15/h2-10,13,23-25H,11-12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513424 (CHEMBL4474829) Show SMILES CCC(=O)Nc1nc(C)c([nH]1)-c1cn(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C25H22N4O3S/c1-3-23(30)27-25-26-16(2)24(28-25)20-15-29(21-13-7-6-12-19(20)21)33(31,32)22-14-8-10-17-9-4-5-11-18(17)22/h4-15H,3H2,1-2H3,(H2,26,27,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513437 (CHEMBL4469147) Show SMILES CC(=O)Nc1nc(C)c([nH]1)-c1ccc2ccn(c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H18N4O3S/c1-13-19(23-20(21-13)22-14(2)25)16-9-8-15-10-11-24(18(15)12-16)28(26,27)17-6-4-3-5-7-17/h3-12H,1-2H3,(H2,21,22,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513420 (CHEMBL4466071) Show SMILES CCC(=O)Nc1nc(CC)c([nH]1)-c1cn(c2ccc(OC)cc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H24N4O4S/c1-4-19-22(26-23(24-19)25-21(28)5-2)18-14-27(20-12-11-15(31-3)13-17(18)20)32(29,30)16-9-7-6-8-10-16/h6-14H,4-5H2,1-3H3,(H2,24,25,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513406 (CHEMBL4483304) Show SMILES CCC(=O)Nc1nc(C)c([nH]1)-c1ccc2ccn(c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H20N4O3S/c1-3-19(26)23-21-22-14(2)20(24-21)16-10-9-15-11-12-25(18(15)13-16)29(27,28)17-7-5-4-6-8-17/h4-13H,3H2,1-2H3,(H2,22,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513419 (CHEMBL4592085) Show SMILES COc1ccc2n(cc(-c3cnc(NC(C)=O)[nH]3)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H18N4O4S/c1-13(25)22-20-21-11-18(23-20)17-12-24(19-9-8-14(28-2)10-16(17)19)29(26,27)15-6-4-3-5-7-15/h3-12H,1-2H3,(H2,21,22,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513390 (CHEMBL4516784) Show SMILES Cl.CCc1nc(N)[nH]c1-c1cn(c2ccc(OC)cc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H20N4O3S/c1-3-17-19(23-20(21)22-17)16-12-24(18-10-9-13(27-2)11-15(16)18)28(25,26)14-7-5-4-6-8-14/h4-12H,3H2,1-2H3,(H3,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504849 (CHEMBL4434670) Show SMILES CC(CSc1nc2ccccc2c(=O)n1-c1ccc(Cl)cc1)N(C)C Show InChI InChI=1S/C19H20ClN3OS/c1-13(22(2)3)12-25-19-21-17-7-5-4-6-16(17)18(24)23(19)15-10-8-14(20)9-11-15/h4-11,13H,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to 5-HT6R (unknown origin) assessed as inhibitory constant				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513426 (CHEMBL4453733) Show SMILES COc1ccc2n(cc(-c3[nH]c(NCC(F)F)nc3C)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H20F2N4O3S/c1-13-20(26-21(25-13)24-11-19(22)23)17-12-27(18-9-8-14(30-2)10-16(17)18)31(28,29)15-6-4-3-5-7-15/h3-10,12,19H,11H2,1-2H3,(H2,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504851 (CHEMBL4483706) Show SMILES N=C(NC1=NC2CCCCC2C(=O)N1)N1CCC(Cc2ccccc2)CC1 |t:3| Show InChI InChI=1S/C21H29N5O/c22-20(25-21-23-18-9-5-4-8-17(18)19(27)24-21)26-12-10-16(11-13-26)14-15-6-2-1-3-7-15/h1-3,6-7,16-18H,4-5,8-14H2,(H3,22,23,24,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to 5-HT6R (unknown origin) assessed as inhibitory constant				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50504812 (CHEMBL4536315) Show SMILES COc1ccc2[nH]c(C)c(CCNCc3ccc(o3)-c3ccc(O)cc3)c2c1 Show InChI InChI=1S/C23H24N2O3/c1-15-20(21-13-18(27-2)7-9-22(21)25-15)11-12-24-14-19-8-10-23(28-19)16-3-5-17(26)6-4-16/h3-10,13,24-26H,11-12,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513413 (CHEMBL4520003) Show SMILES COc1ccc2n(cc(-c3[nH]c(NCc4ccccc4)nc3C)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H24N4O3S/c1-18-25(29-26(28-18)27-16-19-9-5-3-6-10-19)23-17-30(24-14-13-20(33-2)15-22(23)24)34(31,32)21-11-7-4-8-12-21/h3-15,17H,16H2,1-2H3,(H2,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001 BindingDB Entry DOI: 10.7270/Q2S185TZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50504843 (CHEMBL4438434) Show SMILES Cc1ccc2[nH]cc(CCNCc3ccc(o3)-c3ccc(O)cc3)c2c1 Show InChI InChI=1S/C22H22N2O2/c1-15-2-8-21-20(12-15)17(13-24-21)10-11-23-14-19-7-9-22(26-19)16-3-5-18(25)6-4-16/h2-9,12-13,23-25H,10-11,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to human 5-HT2AR expressed in HEK293 cells by competitive binding assay				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111857 BindingDB Entry DOI: 10.7270/Q2833W92
					More data for this Ligand-Target Pair

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