Compile Data Set for Download or QSAR

Found 99 hits with Last Name = 'norcross' and Initial = 'nr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycylpeptide N-tetradecanoyltransferase (Leishmania major)	BDBM50364113 (CHEMBL1230468) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of Leishmania major N-myristoyltransferase using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins ...				J Med Chem 55: 140-52 (2012) Article DOI: 10.1021/jm201091t BindingDB Entry DOI: 10.7270/Q25Q4WK9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycylpeptide N-tetradecanoyltransferase 2 (Homo sapiens (Human))	BDBM50364113 (CHEMBL1230468) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 2 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50364113 (CHEMBL1230468) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins prior sub...				J Med Chem 55: 140-52 (2012) Article DOI: 10.1021/jm201091t BindingDB Entry DOI: 10.7270/Q25Q4WK9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50364113 (CHEMBL1230468) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033480 (CHEMBL3357697) Show SMILES CN1CCC(CCCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C22H32Cl2N4O2S/c1-15-21(16(2)28(4)25-15)26-31(29,30)22-19(23)13-18(14-20(22)24)8-6-5-7-17-9-11-27(3)12-10-17/h13-14,17,26H,5-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033485 (CHEMBL3357702) Show SMILES CN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C22H26Cl2N6O2S/c1-14-21(15(2)28(3)27-14)29(4)33(31,32)22-18(23)11-17(12-19(22)24)16-5-6-26-20(13-16)30-9-7-25-8-10-30/h5-6,11-13,25H,7-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033418 (CHEMBL3357685) Show SMILES CC(C)Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C24H30Cl2N6O2S/c1-15(2)11-21-23(16(3)31(4)29-21)30-35(33,34)24-19(25)12-18(13-20(24)26)17-5-6-28-22(14-17)32-9-7-27-8-10-32/h5-6,12-15,27,30H,7-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033616 (CHEMBL3358119) Show SMILES Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C22H30Cl2F2N4O2S/c1-14-20(15(2)29(3)28-14)30(22(25)26)33(31,32)21-18(23)12-17(13-19(21)24)7-5-4-6-16-8-10-27-11-9-16/h12-13,16,22,27H,4-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033617 (CHEMBL3358120) Show SMILES CN1CCC(CCCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C23H32Cl2F2N4O2S/c1-15-21(16(2)30(4)28-15)31(23(26)27)34(32,33)22-19(24)13-18(14-20(22)25)8-6-5-7-17-9-11-29(3)12-10-17/h13-14,17,23H,5-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033618 (CHEMBL3358121) Show SMILES CN1CCC(CC1)OCCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C Show InChI InChI=1S/C22H30Cl2F2N4O3S/c1-14-20(15(2)29(4)27-14)30(22(25)26)34(31,32)21-18(23)12-16(13-19(21)24)6-5-11-33-17-7-9-28(3)10-8-17/h12-13,17,22H,5-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033482 (CHEMBL3357699) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C21H30Cl2N4O2S/c1-14-20(15(2)27(3)25-14)26-30(28,29)21-18(22)12-17(13-19(21)23)7-5-4-6-16-8-10-24-11-9-16/h12-13,16,24,26H,4-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50364135 (CHEMBL1951295) Show SMILES CN1CCN(Cc2cccc(c2)-c2cc(Cl)c(c(Cl)c2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C24H29Cl2N5O2S/c1-16-23(17(2)30(4)27-16)28-34(32,33)24-21(25)13-20(14-22(24)26)19-7-5-6-18(12-19)15-31-10-8-29(3)9-11-31/h5-7,12-14,28H,8-11,15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins prior sub...				J Med Chem 55: 140-52 (2012) Article DOI: 10.1021/jm201091t BindingDB Entry DOI: 10.7270/Q25Q4WK9
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033478 (CHEMBL3357695) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C20H28Cl2N4O2S/c1-13-19(14(2)26(3)24-13)25-29(27,28)20-17(21)11-16(12-18(20)22)6-4-5-15-7-9-23-10-8-15/h11-12,15,23,25H,4-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033619 (CHEMBL3358122) Show SMILES CN(C)CCCCCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C Show InChI InChI=1S/C21H30Cl2F2N4O2S/c1-14-19(15(2)28(5)26-14)29(21(24)25)32(30,31)20-17(22)12-16(13-18(20)23)10-8-6-7-9-11-27(3)4/h12-13,21H,6-11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033414 (CHEMBL3357681) Show SMILES Cc1c(NS(=O)(=O)c2c(Cl)cc(cc2Cl)-c2ccnc(c2)N2CCNCC2)cnn1C Show InChI InChI=1S/C20H22Cl2N6O2S/c1-13-18(12-25-27(13)2)26-31(29,30)20-16(21)9-15(10-17(20)22)14-3-4-24-19(11-14)28-7-5-23-6-8-28/h3-4,9-12,23,26H,5-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033614 (CHEMBL3358117) Show SMILES Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C21H28Cl2F2N4O2S/c1-13-19(14(2)28(3)27-13)29(21(24)25)32(30,31)20-17(22)11-16(12-18(20)23)6-4-5-15-7-9-26-10-8-15/h11-12,15,21,26H,4-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033487 (CHEMBL3357704) Show SMILES CN1CCN(Cc2cccc(c2)-c2ccc(cc2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C24H31N5O2S/c1-18-24(19(2)28(4)25-18)26-32(30,31)23-10-8-21(9-11-23)22-7-5-6-20(16-22)17-29-14-12-27(3)13-15-29/h5-11,16,26H,12-15,17H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033588 (CHEMBL3358114) Show SMILES CN1CCC(CCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C22H30Cl2F2N4O2S/c1-14-20(15(2)29(4)27-14)30(22(25)26)33(31,32)21-18(23)12-17(13-19(21)24)7-5-6-16-8-10-28(3)11-9-16/h12-13,16,22H,5-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033415 (CHEMBL3357682) Show SMILES Cc1nn(C)cc1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C20H22Cl2N6O2S/c1-13-18(12-27(2)25-13)26-31(29,30)20-16(21)9-15(10-17(20)22)14-3-4-24-19(11-14)28-7-5-23-6-8-28/h3-4,9-12,23,26H,5-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033488 (CHEMBL3357705) Show SMILES CN(c1c(C)nn(C)c1C)S(=O)(=O)c1ccc(cc1)-c1cccc(CN2CCN(C)CC2)c1 Show InChI InChI=1S/C25H33N5O2S/c1-19-25(20(2)28(4)26-19)29(5)33(31,32)24-11-9-22(10-12-24)23-8-6-7-21(17-23)18-30-15-13-27(3)14-16-30/h6-12,17H,13-16,18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033420 (CHEMBL3357686) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C22H25Cl2N5O2S/c1-14-21(15(2)28(3)26-14)27-32(30,31)22-19(23)12-17(13-20(22)24)16-5-4-6-18(11-16)29-9-7-25-8-10-29/h4-6,11-13,25,27H,7-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033582 (CHEMBL3358111) Show SMILES CN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCC2CCN(C)CC2)cc1Cl Show InChI InChI=1S/C22H32Cl2N4O2S/c1-15-21(16(2)27(4)25-15)28(5)31(29,30)22-19(23)13-18(14-20(22)24)8-6-7-17-9-11-26(3)12-10-17/h13-14,17H,6-12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033486 (CHEMBL3357703) Show SMILES CN(c1c(C)nn(C)c1C)S(=O)(=O)c1ccc(cc1)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C22H28N6O2S/c1-16-22(17(2)26(3)25-16)27(4)31(29,30)20-7-5-18(6-8-20)19-9-10-24-21(15-19)28-13-11-23-12-14-28/h5-10,15,23H,11-14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033421 (CHEMBL3357687) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1cccc(c1)C1CCNCC1 Show InChI InChI=1S/C23H26Cl2N4O2S/c1-14-22(15(2)29(3)27-14)28-32(30,31)23-20(24)12-19(13-21(23)25)18-6-4-5-17(11-18)16-7-9-26-10-8-16/h4-6,11-13,16,26,28H,7-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033584 (CHEMBL3358113) Show SMILES CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCC2CCN(C)CC2)cc1Cl Show InChI InChI=1S/C23H34Cl2N4O2S/c1-6-29(22-16(2)26-28(5)17(22)3)32(30,31)23-20(24)14-19(15-21(23)25)9-7-8-18-10-12-27(4)13-11-18/h14-15,18H,6-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033422 (CHEMBL3357688) Show SMILES CN1CCN(CC1)c1cc(ccn1)-c1cc(Cl)c(c(Cl)c1)S(=O)(=O)Nc1c(C)nn(C)c1C Show InChI InChI=1S/C22H26Cl2N6O2S/c1-14-21(15(2)29(4)26-14)27-33(31,32)22-18(23)11-17(12-19(22)24)16-5-6-25-20(13-16)30-9-7-28(3)8-10-30/h5-6,11-13,27H,7-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033417 (CHEMBL3357684) Show SMILES CC(C)Cc1c(NS(=O)(=O)c2c(Cl)cc(cc2Cl)-c2ccnc(c2)N2CCNCC2)c(C)nn1C Show InChI InChI=1S/C24H30Cl2N6O2S/c1-15(2)11-21-23(16(3)29-31(21)4)30-35(33,34)24-19(25)12-18(13-20(24)26)17-5-6-28-22(14-17)32-9-7-27-8-10-32/h5-6,12-15,27,30H,7-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033483 (CHEMBL3357700) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCCC2CCNCC2)cc1 Show InChI InChI=1S/C21H32N4O2S/c1-16-21(17(2)25(3)23-16)24-28(26,27)20-10-8-18(9-11-20)6-4-5-7-19-12-14-22-15-13-19/h8-11,19,22,24H,4-7,12-15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033428 (CHEMBL3357693) Show SMILES CN1CCC(CCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C21H30Cl2N4O2S/c1-14-20(15(2)27(4)24-14)25-30(28,29)21-18(22)12-17(13-19(21)23)7-5-6-16-8-10-26(3)11-9-16/h12-13,16,25H,5-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033481 (CHEMBL3357698) Show SMILES CN1CCC(CCCCc2ccc(cc2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C22H34N4O2S/c1-17-22(18(2)26(4)23-17)24-29(27,28)21-11-9-19(10-12-21)7-5-6-8-20-13-15-25(3)16-14-20/h9-12,20,24H,5-8,13-16H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033622 (CHEMBL3358125) Show SMILES CN1CCC[C@@H]1COCCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C |r| Show InChI InChI=1S/C22H30Cl2F2N4O3S/c1-14-20(15(2)29(4)27-14)30(22(25)26)34(31,32)21-18(23)11-16(12-19(21)24)7-6-10-33-13-17-8-5-9-28(17)3/h11-12,17,22H,5-10,13H2,1-4H3/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033624 (CHEMBL3358127) Show SMILES [H][C@]12CCCN1CCN(CCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C)C2 |r| Show InChI InChI=1S/C23H31Cl2F2N5O2S/c1-15-21(16(2)29(3)28-15)32(23(26)27)35(33,34)22-19(24)12-17(13-20(22)25)6-4-8-30-10-11-31-9-5-7-18(31)14-30/h12-13,18,23H,4-11,14H2,1-3H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033416 (CHEMBL3357683) Show SMILES Cn1cc(NS(=O)(=O)c2c(Cl)cc(cc2Cl)-c2ccnc(c2)N2CCNCC2)cn1 Show InChI InChI=1S/C19H20Cl2N6O2S/c1-26-12-15(11-24-26)25-30(28,29)19-16(20)8-14(9-17(19)21)13-2-3-23-18(10-13)27-6-4-22-5-7-27/h2-3,8-12,22,25H,4-7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033620 (CHEMBL3358123) Show SMILES CN1CCC[C@H]1COCCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C |r| Show InChI InChI=1S/C22H30Cl2F2N4O3S/c1-14-20(15(2)29(4)27-14)30(22(25)26)34(31,32)21-18(23)11-16(12-19(21)24)7-6-10-33-13-17-8-5-9-28(17)3/h11-12,17,22H,5-10,13H2,1-4H3/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50536194 (CHEMBL4569641) Show SMILES C(C1CCN(CC1)c1cc(nc(n1)-c1ccncc1)-c1cccnc1)N1CCOCC1 Show InChI InChI=1S/C24H28N6O/c1-2-21(17-26-7-1)22-16-23(28-24(27-22)20-3-8-25-9-4-20)30-10-5-19(6-11-30)18-29-12-14-31-15-13-29/h1-4,7-9,16-17,19H,5-6,10-15,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human CYP3A4 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Diethoxyfluore...				J Med Chem 59: 6101-20 (2016) Article DOI: 10.1021/acs.jmedchem.6b00028 BindingDB Entry DOI: 10.7270/Q2H41VZX
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50536191 (CHEMBL4584780) Show SMILES C1CN(CCO1)C1CCN(CC1)c1cc(nc(n1)-c1ccncc1)-c1cccnc1 Show InChI InChI=1S/C23H26N6O/c1-2-19(17-25-7-1)21-16-22(27-23(26-21)18-3-8-24-9-4-18)29-10-5-20(6-11-29)28-12-14-30-15-13-28/h1-4,7-9,16-17,20H,5-6,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human CYP3A4 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Diethoxyfluore...				J Med Chem 59: 6101-20 (2016) Article DOI: 10.1021/acs.jmedchem.6b00028 BindingDB Entry DOI: 10.7270/Q2H41VZX
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50536193 (CHEMBL548646 | GNF-Pf-1447 | TCMDC-125419) Show SMILES C1Cc2ccccc2CN1c1cc(nc(n1)-c1ccncc1)-c1cccnc1 Show InChI InChI=1S/C23H19N5/c1-2-5-20-16-28(13-9-17(20)4-1)22-14-21(19-6-3-10-25-15-19)26-23(27-22)18-7-11-24-12-8-18/h1-8,10-12,14-15H,9,13,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human CYP3A4 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Diethoxyfluore...				J Med Chem 59: 6101-20 (2016) Article DOI: 10.1021/acs.jmedchem.6b00028 BindingDB Entry DOI: 10.7270/Q2H41VZX
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50364127 (CHEMBL1951287) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(nc1)N1CCCC(C1)N1CCNCC1 Show InChI InChI=1S/C20H31N7O2S/c1-15-20(16(2)25(3)23-15)24-30(28,29)18-6-7-19(22-13-18)27-10-4-5-17(14-27)26-11-8-21-9-12-26/h6-7,13,17,21,24H,4-5,8-12,14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins prior sub...				J Med Chem 55: 140-52 (2012) Article DOI: 10.1021/jm201091t BindingDB Entry DOI: 10.7270/Q25Q4WK9
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50364136 (CHEMBL1951296) Show SMILES CCN(CC)Cc1cccc(c1)-c1cc(Cl)c(c(Cl)c1)S(=O)(=O)Nc1c(C)nn(C)c1C Show InChI InChI=1S/C23H28Cl2N4O2S/c1-6-29(7-2)14-17-9-8-10-18(11-17)19-12-20(24)23(21(25)13-19)32(30,31)27-22-15(3)26-28(5)16(22)4/h8-13,27H,6-7,14H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins prior sub...				J Med Chem 55: 140-52 (2012) Article DOI: 10.1021/jm201091t BindingDB Entry DOI: 10.7270/Q25Q4WK9
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033479 (CHEMBL3357696) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCC2CCNCC2)cc1 Show InChI InChI=1S/C20H30N4O2S/c1-15-20(16(2)24(3)22-15)23-27(25,26)19-9-7-17(8-10-19)5-4-6-18-11-13-21-14-12-18/h7-10,18,21,23H,4-6,11-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033623 (CHEMBL3358126) Show SMILES CN1CCCC[C@@H]1COCCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C |r| Show InChI InChI=1S/C23H32Cl2F2N4O3S/c1-15-21(16(2)30(4)28-15)31(23(26)27)35(32,33)22-19(24)12-17(13-20(22)25)8-7-11-34-14-18-9-5-6-10-29(18)3/h12-13,18,23H,5-11,14H2,1-4H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033615 (CHEMBL3358118) Show SMILES CN1CCN(CCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C21H29Cl2F2N5O2S/c1-14-19(15(2)28(4)26-14)30(21(24)25)33(31,32)20-17(22)12-16(13-18(20)23)6-5-7-29-10-8-27(3)9-11-29/h12-13,21H,5-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033595 (CHEMBL3358115) Show SMILES CN1CCC(CCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(CC(F)F)c2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C23H32Cl2F2N4O2S/c1-15-22(16(2)30(4)28-15)31(14-21(26)27)34(32,33)23-19(24)12-18(13-20(23)25)7-5-6-17-8-10-29(3)11-9-17/h12-13,17,21H,5-11,14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033472 (CHEMBL3357694) Show SMILES CN1CCC(CCCc2ccc(cc2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C21H32N4O2S/c1-16-21(17(2)25(4)22-16)23-28(26,27)20-10-8-18(9-11-20)6-5-7-19-12-14-24(3)15-13-19/h8-11,19,23H,5-7,12-15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033497 (CHEMBL3357706) Show SMILES CN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCN2CCN(C)CC2)cc1Cl Show InChI InChI=1S/C21H31Cl2N5O2S/c1-15-20(16(2)26(4)24-15)27(5)31(29,30)21-18(22)13-17(14-19(21)23)7-6-8-28-11-9-25(3)10-12-28/h13-14H,6-12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033608 (CHEMBL3358116) Show SMILES CN1CCC(CCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(CC(F)(F)F)c2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C23H31Cl2F3N4O2S/c1-15-21(16(2)31(4)29-15)32(14-23(26,27)28)35(33,34)22-19(24)12-18(13-20(22)25)7-5-6-17-8-10-30(3)11-9-17/h12-13,17H,5-11,14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033621 (CHEMBL3358124) Show SMILES CN1CCCC[C@H]1COCCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C |r| Show InChI InChI=1S/C23H32Cl2F2N4O3S/c1-15-21(16(2)30(4)28-15)31(23(26)27)35(32,33)22-19(24)12-17(13-20(22)25)8-7-11-34-14-18-9-5-6-10-29(18)3/h12-13,18,23H,5-11,14H2,1-4H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033581 (CHEMBL3358110) Show SMILES CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCCCCn2ccnc2)cc1Cl Show InChI InChI=1S/C23H31Cl2N5O2S/c1-5-30(22-17(2)27-28(4)18(22)3)33(31,32)23-20(24)14-19(15-21(23)25)10-8-6-7-9-12-29-13-11-26-16-29/h11,13-16H,5-10,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033502 (CHEMBL3358108) Show SMILES CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCN2CCN(C)CC2)cc1Cl Show InChI InChI=1S/C22H33Cl2N5O2S/c1-6-29(21-16(2)25-27(5)17(21)3)32(30,31)22-19(23)14-18(15-20(22)24)8-7-9-28-12-10-26(4)11-13-28/h14-15H,6-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033425 (CHEMBL3357691) Show SMILES CN1CCN(CCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C20H29Cl2N5O2S/c1-14-19(15(2)26(4)23-14)24-30(28,29)20-17(21)12-16(13-18(20)22)6-5-7-27-10-8-25(3)9-11-27/h12-13,24H,5-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair

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