Compile Data Set for Download or QSAR

Found 60 hits with Last Name = 'novick' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50055569 (CHEMBL46937 | [2-(4-Butyl-phenyl)-6-hydroxy-benzo[...) Show SMILES CCCCc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1 Show InChI InChI=1S/C32H35NO3S/c1-2-3-7-23-8-10-25(11-9-23)32-30(28-17-14-26(34)22-29(28)37-32)31(35)24-12-15-27(16-13-24)36-21-20-33-18-5-4-6-19-33/h8-17,22,34H,2-7,18-21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from ERalpha after 4 hrs by scintillation counting				ACS Med Chem Lett 3: 207-210 (2012) Article DOI: 10.1021/ml2002532 BindingDB Entry DOI: 10.7270/Q23F4QP6
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50055569 (CHEMBL46937 | [2-(4-Butyl-phenyl)-6-hydroxy-benzo[...) Show SMILES CCCCc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1 Show InChI InChI=1S/C32H35NO3S/c1-2-3-7-23-8-10-25(11-9-23)32-30(28-17-14-26(34)22-29(28)37-32)31(35)24-12-15-27(16-13-24)36-21-20-33-18-5-4-6-19-33/h8-17,22,34H,2-7,18-21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to ERalpha ligand binding domain				ACS Med Chem Lett 3: 207-210 (2012) Article DOI: 10.1021/ml2002532 BindingDB Entry DOI: 10.7270/Q23F4QP6
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19441 (2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...) Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1 Show InChI InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from ERalpha after 4 hrs by scintillation counting				ACS Med Chem Lett 3: 207-210 (2012) Article DOI: 10.1021/ml2002532 BindingDB Entry DOI: 10.7270/Q23F4QP6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM19441 (2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...) Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1 Show InChI InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to ERalpha ligand binding domain				ACS Med Chem Lett 3: 207-210 (2012) Article DOI: 10.1021/ml2002532 BindingDB Entry DOI: 10.7270/Q23F4QP6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM20608 (4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...) Show SMILES CC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 Show InChI InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from ERalpha after 4 hrs by scintillation counting				ACS Med Chem Lett 3: 207-210 (2012) Article DOI: 10.1021/ml2002532 BindingDB Entry DOI: 10.7270/Q23F4QP6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM20607 ((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...) Show SMILES CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 Show InChI InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from ERbeta after 4 hrs by scintillation counting				ACS Med Chem Lett 3: 207-210 (2012) Article DOI: 10.1021/ml2002532 BindingDB Entry DOI: 10.7270/Q23F4QP6
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM19441 (2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...) Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1 Show InChI InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from ERbeta after 4 hrs by scintillation counting				ACS Med Chem Lett 3: 207-210 (2012) Article DOI: 10.1021/ml2002532 BindingDB Entry DOI: 10.7270/Q23F4QP6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM50055569 (CHEMBL46937 | [2-(4-Butyl-phenyl)-6-hydroxy-benzo[...) Show SMILES CCCCc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1 Show InChI InChI=1S/C32H35NO3S/c1-2-3-7-23-8-10-25(11-9-23)32-30(28-17-14-26(34)22-29(28)37-32)31(35)24-12-15-27(16-13-24)36-21-20-33-18-5-4-6-19-33/h8-17,22,34H,2-7,18-21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]estradiol from ERbeta after 4 hrs by scintillation counting				ACS Med Chem Lett 3: 207-210 (2012) Article DOI: 10.1021/ml2002532 BindingDB Entry DOI: 10.7270/Q23F4QP6
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50557257 (CHEMBL4789047) Show SMILES Cc1ccc(CN(CC(O)COc2cccc3[nH]ccc23)C(C)(C)C)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to beta1 adrenoceptor (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01450 BindingDB Entry DOI: 10.7270/Q2MS3XF8
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50557257 (CHEMBL4789047) Show SMILES Cc1ccc(CN(CC(O)COc2cccc3[nH]ccc23)C(C)(C)C)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to beta2 adrenoceptor (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01450 BindingDB Entry DOI: 10.7270/Q2MS3XF8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50557257 (CHEMBL4789047) Show SMILES Cc1ccc(CN(CC(O)COc2cccc3[nH]ccc23)C(C)(C)C)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to 5HT1A receptor (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01450 BindingDB Entry DOI: 10.7270/Q2MS3XF8
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466993 (CHEMBL4289691) Show SMILES Nc1cc(c(s1)C(=O)c1ccccc1Cl)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C17H10Cl3NOS/c18-10-5-9(6-11(19)7-10)13-8-15(21)23-17(13)16(22)12-3-1-2-4-14(12)20/h1-8H,21H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466987 (CHEMBL4292343) Show SMILES CC(C)Oc1cc(Br)cc(c1)-c1ccsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C20H16BrClO2S/c1-12(2)24-15-10-13(9-14(21)11-15)16-7-8-25-20(16)19(23)17-5-3-4-6-18(17)22/h3-12H,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466992 (CHEMBL4289114) Show SMILES FC(F)(F)c1cc(Br)cc(c1)-c1ncsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C17H8BrClF3NOS/c18-11-6-9(5-10(7-11)17(20,21)22)14-16(25-8-23-14)15(24)12-3-1-2-4-13(12)19/h1-8H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467002 (CHEMBL4284016) Show SMILES FC(F)(F)c1cccc(c1)-c1ncsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C17H9ClF3NOS/c18-13-7-2-1-6-12(13)15(23)16-14(22-9-24-16)10-4-3-5-11(8-10)17(19,20)21/h1-9H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466991 (CHEMBL4276720) Show SMILES Nc1cc(c(s1)C(=O)c1ccccc1Cl)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C18H11ClF3NOS/c19-14-7-2-1-6-12(14)16(24)17-13(9-15(23)25-17)10-4-3-5-11(8-10)18(20,21)22/h1-9H,23H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466998 (CHEMBL4291888) Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H14F3NO2S/c1-25-15-8-3-2-7-13(15)17(24)18-14(10-16(23)26-18)11-5-4-6-12(9-11)19(20,21)22/h2-10H,23H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466997 (CHEMBL4284644) Show SMILES Clc1cc(ccn1)-c1ccsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C16H9Cl2NOS/c17-13-4-2-1-3-12(13)15(20)16-11(6-8-21-16)10-5-7-19-14(18)9-10/h1-9H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467006 (CHEMBL4286904) Show SMILES Clc1ccccc1C(=O)c1sccc1-c1cccc2ccccc12 Show InChI InChI=1S/C21H13ClOS/c22-19-11-4-3-9-18(19)20(23)21-17(12-13-24-21)16-10-5-7-14-6-1-2-8-15(14)16/h1-13H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467011 (CHEMBL4293341) Show SMILES Nc1ccc(C(=O)c2ccccc2Cl)c(c1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H13ClF3NO/c21-18-7-2-1-6-16(18)19(26)15-9-8-14(25)11-17(15)12-4-3-5-13(10-12)20(22,23)24/h1-11H,25H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467004 (CHEMBL4288028) Show SMILES COc1ccccc1C(=O)c1scnc1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C18H12F3NO2S/c1-24-14-8-3-2-7-13(14)16(23)17-15(22-10-25-17)11-5-4-6-12(9-11)18(19,20)21/h2-10H,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466990 (CHEMBL4281271) Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cccc(Cl)c1 Show InChI InChI=1S/C18H14ClNO2S/c1-22-15-8-3-2-7-13(15)17(21)18-14(10-16(20)23-18)11-5-4-6-12(19)9-11/h2-10H,20H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467003 (CHEMBL4290788) Show SMILES FC(F)(F)c1cccc(c1)-c1ccccc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C20H12ClF3O/c21-18-11-4-3-10-17(18)19(25)16-9-2-1-8-15(16)13-6-5-7-14(12-13)20(22,23)24/h1-12H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467007 (CHEMBL4284441) Show SMILES COc1ccccc1C(=O)c1sccc1-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13ClO2S/c1-21-16-8-3-2-7-15(16)17(20)18-14(9-10-22-18)12-5-4-6-13(19)11-12/h2-11H,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466986 (CHEMBL4276733) Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C18H13Cl2NO2S/c1-23-15-5-3-2-4-13(15)17(22)18-14(9-16(21)24-18)10-6-11(19)8-12(20)7-10/h2-9H,21H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466989 (CHEMBL4288937) Show SMILES COc1ccccc1C(=O)c1sccc1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H13F3O2S/c1-24-16-8-3-2-7-15(16)17(23)18-14(9-10-25-18)12-5-4-6-13(11-12)19(20,21)22/h2-11H,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467010 (CHEMBL4285419) Show SMILES FC(F)(F)c1cccc(c1)-c1ccsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C18H10ClF3OS/c19-15-7-2-1-6-14(15)16(23)17-13(8-9-24-17)11-4-3-5-12(10-11)18(20,21)22/h1-10H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467008 (CHEMBL4281036) Show SMILES COc1ccccc1C(=O)c1sccc1-c1ccnc(Cl)c1 Show InChI InChI=1S/C17H12ClNO2S/c1-21-14-5-3-2-4-13(14)16(20)17-12(7-9-22-17)11-6-8-19-15(18)10-11/h2-10H,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466996 (CHEMBL4292696) Show SMILES Nc1cc(c(s1)C(=O)c1ccccc1Cl)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H10ClF6NOS/c20-14-4-2-1-3-12(14)16(28)17-13(8-15(27)29-17)9-5-10(18(21,22)23)7-11(6-9)19(24,25)26/h1-8H,27H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467009 (CHEMBL4284673) Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1ccnc(Cl)c1 Show InChI InChI=1S/C17H13ClN2O2S/c1-22-13-5-3-2-4-11(13)16(21)17-12(9-15(19)23-17)10-6-7-20-14(18)8-10/h2-9H,19H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50467006 (CHEMBL4286904) Show SMILES Clc1ccccc1C(=O)c1sccc1-c1cccc2ccccc12 Show InChI InChI=1S/C21H13ClOS/c22-19-11-4-3-9-18(19)20(23)21-17(12-13-24-21)16-10-5-7-14-6-1-2-8-15(14)16/h1-13H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467005 (CHEMBL4277389) Show SMILES Clc1ccccc1C(=O)c1sccc1-c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C23H15ClOS/c24-21-12-5-4-11-20(21)22(25)23-19(13-14-26-23)18-10-6-9-17(15-18)16-7-2-1-3-8-16/h1-15H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467001 (CHEMBL4285780) Show SMILES Clc1ccccc1C(=O)c1sccc1-c1ccc2OCOc2c1 Show InChI InChI=1S/C18H11ClO3S/c19-14-4-2-1-3-13(14)17(20)18-12(7-8-23-18)11-5-6-15-16(9-11)22-10-21-15/h1-9H,10H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50466987 (CHEMBL4292343) Show SMILES CC(C)Oc1cc(Br)cc(c1)-c1ccsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C20H16BrClO2S/c1-12(2)24-15-10-13(9-14(21)11-15)16-7-8-25-20(16)19(23)17-5-3-4-6-18(17)22/h3-12H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466985 (CHEMBL4293998) Show SMILES Clc1ccc(cc1Cl)-c1ccsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C17H9Cl3OS/c18-13-4-2-1-3-12(13)16(21)17-11(7-8-22-17)10-5-6-14(19)15(20)9-10/h1-9H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466994 (CHEMBL4283486) Show SMILES Clc1cccc(c1)-c1ccsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C17H10Cl2OS/c18-12-5-3-4-11(10-12)13-8-9-21-17(13)16(20)14-6-1-2-7-15(14)19/h1-10H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50460723 (CHEMBL4229273) Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C17H10ClF3N2OS/c18-12-7-2-1-6-11(12)14(24)15-13(23-16(22)25-15)9-4-3-5-10(8-9)17(19,20)21/h1-8H,(H2,22,23)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50467007 (CHEMBL4284441) Show SMILES COc1ccccc1C(=O)c1sccc1-c1cccc(Cl)c1 Show InChI InChI=1S/C18H13ClO2S/c1-21-16-8-3-2-7-15(16)17(20)18-14(9-10-22-18)12-5-4-6-13(19)11-12/h2-11H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50466989 (CHEMBL4288937) Show SMILES COc1ccccc1C(=O)c1sccc1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H13F3O2S/c1-24-16-8-3-2-7-15(16)17(23)18-14(9-10-25-18)12-5-4-6-13(11-12)19(20,21)22/h2-11H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466995 (CHEMBL4285720) Show SMILES Clc1cccc(c1)-c1ncsc1C(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H8Cl3NOS/c17-11-3-1-2-9(6-11)14-16(22-8-20-14)15(21)10-4-5-12(18)13(19)7-10/h1-8H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466988 (CHEMBL4292527) Show SMILES CC(C)(C)c1ccc(cc1)-c1ccsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C21H19ClOS/c1-21(2,3)15-10-8-14(9-11-15)16-12-13-24-20(16)19(23)17-6-4-5-7-18(17)22/h4-13H,1-3H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50466986 (CHEMBL4276733) Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C18H13Cl2NO2S/c1-23-15-5-3-2-4-13(15)17(22)18-14(9-16(21)24-18)10-6-11(19)8-12(20)7-10/h2-9H,21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466999 (CHEMBL4294059) Show SMILES Clc1cccc(c1)-c1ncsc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C16H9Cl2NOS/c17-11-5-3-4-10(8-11)14-16(21-9-19-14)15(20)12-6-1-2-7-13(12)18/h1-9H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466998 (CHEMBL4291888) Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H14F3NO2S/c1-25-15-8-3-2-7-13(15)17(24)18-14(10-16(23)26-18)11-5-4-6-12(9-11)19(20,21)22/h2-10H,23H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at GAL4-DNA binding domain-fused human RORbeta ligand binding domain expressed in HEK293T cells incubated for 20 hrs by luci...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50467003 (CHEMBL4290788) Show SMILES FC(F)(F)c1cccc(c1)-c1ccccc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C20H12ClF3O/c21-18-11-4-3-10-17(18)19(25)16-9-2-1-8-15(16)13-6-5-7-14(12-13)20(22,23)24/h1-12H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50467000 (CHEMBL4287249) Show SMILES Clc1cccc(c1)-c1ncccc1C(=O)c1ccccc1Cl Show InChI InChI=1S/C18H11Cl2NO/c19-13-6-3-5-12(11-13)17-15(8-4-10-21-17)18(22)14-7-1-2-9-16(14)20/h1-11H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50466990 (CHEMBL4281271) Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cccc(Cl)c1 Show InChI InChI=1S/C18H14ClNO2S/c1-22-15-8-3-2-7-13(15)17(21)18-14(10-16(20)23-18)11-5-4-6-12(19)9-11/h2-10H,20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50466993 (CHEMBL4289691) Show SMILES Nc1cc(c(s1)C(=O)c1ccccc1Cl)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C17H10Cl3NOS/c18-10-5-9(6-11(19)7-10)13-8-15(21)23-17(13)16(22)12-3-1-2-4-14(12)20/h1-8H,21H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466993 (CHEMBL4289691) Show SMILES Nc1cc(c(s1)C(=O)c1ccccc1Cl)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C17H10Cl3NOS/c18-10-5-9(6-11(19)7-10)13-8-15(21)23-17(13)16(22)12-3-1-2-4-14(12)20/h1-8H,21H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at GAL4-DNA binding domain-fused human RORbeta ligand binding domain expressed in HEK293T cells incubated for 20 hrs by luci...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50466990 (CHEMBL4281271) Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cccc(Cl)c1 Show InChI InChI=1S/C18H14ClNO2S/c1-22-15-8-3-2-7-13(15)17(21)18-14(10-16(20)23-18)11-5-4-6-12(19)9-11/h2-10H,20H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at GAL4-DNA binding domain-fused human RORbeta ligand binding domain expressed in HEK293T cells incubated for 20 hrs by luci...				Bioorg Med Chem Lett 28: 3210-3215 (2018) Article DOI: 10.1016/j.bmcl.2018.08.017 BindingDB Entry DOI: 10.7270/Q2KW5JPB
					More data for this Ligand-Target Pair

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