Compile Data Set for Download or QSAR

Found 45 hits with Last Name = 'obermoser' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50207272 (CHEMBL3960906) Show SMILES O=C(CN1c2ccccc2Sc2ccccc12)NNC(=S)NCc1ccccc1 Show InChI InChI=1S/C22H20N4OS2/c27-21(24-25-22(28)23-14-16-8-2-1-3-9-16)15-26-17-10-4-6-12-19(17)29-20-13-7-5-11-18(20)26/h1-13H,14-15H2,(H,24,27)(H2,23,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.17E+4	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in African green monkey COS7 cells after 42 hrs by dual luciferase repo...				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232213 (CHEMBL4069460) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1ccccc1Cl Show InChI InChI=1S/C30H25ClN2O2/c1-2-7-29-32-27-17-16-22(24-9-5-6-11-26(24)31)18-28(27)33(29)19-20-12-14-21(15-13-20)23-8-3-4-10-25(23)30(34)35/h3-6,8-18H,2,7,19H2,1H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50207273 (CHEMBL3891909) Show SMILES FC(F)(F)c1cc(Cc2cc(NS(=O)(=O)c3ccccc3)cc(c2)C(F)(F)F)cc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C27H20F6N2O4S2/c28-26(29,30)20-12-18(14-22(16-20)34-40(36,37)24-7-3-1-4-8-24)11-19-13-21(27(31,32)33)17-23(15-19)35-41(38,39)25-9-5-2-6-10-25/h1-10,12-17,34-35H,11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of Fluoromone from GST-tagged recombinant human PPARgamma ligand binding domain by LanthaScreen TR-FRET assay				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50207274 (CHEMBL3962023) Show SMILES COc1ccc(cc1)-c1cn2cccc(OCc3ccc(Cl)c(Cl)c3)c2n1 Show InChI InChI=1S/C21H16Cl2N2O2/c1-26-16-7-5-15(6-8-16)19-12-25-10-2-3-20(21(25)24-19)27-13-14-4-9-17(22)18(23)11-14/h2-12H,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of Fluoromone from GST-tagged recombinant human PPARgamma ligand binding domain by LanthaScreen TR-FRET assay				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50043280 (4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...) Show SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1nc2ccccc2n1C Show InChI InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in African green monkey COS7 cells after 42 hrs by dual luciferase repo...				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50103521 (Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...) Show SMILES CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1 Show InChI InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of Fluoromone from GST-tagged recombinant human PPARgamma ligand binding domain by LanthaScreen TR-FRET assay				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50207273 (CHEMBL3891909) Show SMILES FC(F)(F)c1cc(Cc2cc(NS(=O)(=O)c3ccccc3)cc(c2)C(F)(F)F)cc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C27H20F6N2O4S2/c28-26(29,30)20-12-18(14-22(16-20)34-40(36,37)24-7-3-1-4-8-24)11-19-13-21(27(31,32)33)17-23(15-19)35-41(38,39)25-9-5-2-6-10-25/h1-10,12-17,34-35H,11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in African green monkey COS7 cells after 42 hrs by dual luciferase repo...				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50043280 (4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...) Show SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1nc2ccccc2n1C Show InChI InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of Fluoromone from GST-tagged recombinant human PPARgamma ligand binding domain by LanthaScreen TR-FRET assay				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50207275 (CHEMBL3913928) Show SMILES CSc1nc(Sc2nnc([nH]2)-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc(Sc2nnc([nH]2)-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)n1 Show InChI InChI=1S/C25H12F12N8S3/c1-46-19-38-15(47-20-40-17(42-44-20)9-2-11(22(26,27)28)6-12(3-9)23(29,30)31)8-16(39-19)48-21-41-18(43-45-21)10-4-13(24(32,33)34)7-14(5-10)25(35,36)37/h2-8H,1H3,(H,40,42,44)(H,41,43,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of Fluoromone from GST-tagged recombinant human PPARgamma ligand binding domain by LanthaScreen TR-FRET assay				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50207276 (CHEMBL3973020) Show SMILES Clc1ccc(cc1)-c1c(cnn1S(=O)(=O)c1ccc(Cl)cc1Cl)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H12Cl4N2O4S2/c22-14-3-1-13(2-4-14)21-20(32(28,29)17-8-5-15(23)6-9-17)12-26-27(21)33(30,31)19-10-7-16(24)11-18(19)25/h1-12H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of Fluoromone from GST-tagged recombinant human PPARgamma ligand binding domain by LanthaScreen TR-FRET assay				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50103521 (Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...) Show SMILES CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1 Show InChI InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in African green monkey COS7 cells after 42 hrs by dual luciferase repo...				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205198 (CHEMBL3976173) Show SMILES CCCCCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C28H30N2O2/c1-2-3-4-5-6-15-27-29-25-13-9-10-14-26(25)30(27)20-21-16-18-22(19-17-21)23-11-7-8-12-24(23)28(31)32/h7-14,16-19H,2-6,15,20H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205199 (CHEMBL3962742) Show SMILES CCCCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(N)=O Show InChI InChI=1S/C27H29N3O/c1-2-3-4-5-14-26-29-24-12-8-9-13-25(24)30(26)19-20-15-17-21(18-16-20)22-10-6-7-11-23(22)27(28)31/h6-13,15-18H,2-5,14,19H2,1H3,(H2,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.06E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205227 (CHEMBL3907308) Show SMILES CCCc1cc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C#N Show InChI InChI=1S/C25H22N2/c1-2-7-23-16-21-8-4-6-11-25(21)27(23)18-19-12-14-20(15-13-19)24-10-5-3-9-22(24)17-26/h3-6,8-16H,2,7,18H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.03E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205228 (CHEMBL3916286) Show SMILES CCCc1cc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C25H23NO2/c1-2-7-21-16-20-8-3-6-11-24(20)26(21)17-18-12-14-19(15-13-18)22-9-4-5-10-23(22)25(27)28/h3-6,8-16H,2,7,17H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205229 (CHEMBL3977198) Show SMILES CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N2O2/c1-2-5-23-25-21-6-3-4-7-22(21)26(23)16-17-8-10-18(11-9-17)19-12-14-20(15-13-19)24(27)28/h3-4,6-15H,2,5,16H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205230 (CHEMBL3912543) Show SMILES CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C#N Show InChI InChI=1S/C24H21N3/c1-2-7-24-26-22-10-5-6-11-23(22)27(24)17-18-12-14-19(15-13-18)21-9-4-3-8-20(21)16-25/h3-6,8-15H,2,7,17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50324039 (4'-[(2-Propyl-1H-benzo[d]imidazol-1-yl)methyl]biph...) Show SMILES CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C24H22N2O2/c1-2-7-23-25-21-10-5-6-11-22(21)26(23)16-17-12-14-18(15-13-17)19-8-3-4-9-20(19)24(27)28/h3-6,8-15H,2,7,16H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.17E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50103521 (Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...) Show SMILES CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1 Show InChI InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205231 (CHEMBL3985281) Show SMILES CCCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(N)=O Show InChI InChI=1S/C26H27N3O/c1-2-3-4-13-25-28-23-11-7-8-12-24(23)29(25)18-19-14-16-20(17-15-19)21-9-5-6-10-22(21)26(27)30/h5-12,14-17H,2-4,13,18H2,1H3,(H2,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205232 (CHEMBL3934455) Show SMILES CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(N)=O Show InChI InChI=1S/C24H23N3O/c1-2-7-23-26-21-10-5-6-11-22(21)27(23)16-17-12-14-18(15-13-17)19-8-3-4-9-20(19)24(25)28/h3-6,8-15H,2,7,16H2,1H3,(H2,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.15E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205240 (CHEMBL3904906) Show SMILES CCCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C26H26N2O2/c1-2-3-4-13-25-27-23-11-7-8-12-24(23)28(25)18-19-14-16-20(17-15-19)21-9-5-6-10-22(21)26(29)30/h5-12,14-17H,2-4,13,18H2,1H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205251 (CHEMBL3984220) Show SMILES CCCC1Sc2ccccc2N1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C24H23NO2S/c1-2-7-23-25(21-10-5-6-11-22(21)28-23)16-17-12-14-18(15-13-17)19-8-3-4-9-20(19)24(26)27/h3-6,8-15,23H,2,7,16H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50043280 (4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...) Show SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1nc2ccccc2n1C Show InChI InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	4.71E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205252 (CHEMBL3905419) Show SMILES CCCCCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(N)=O Show InChI InChI=1S/C28H31N3O/c1-2-3-4-5-6-15-27-30-25-13-9-10-14-26(25)31(27)20-21-16-18-22(19-17-21)23-11-7-8-12-24(23)28(29)32/h7-14,16-19H,2-6,15,20H2,1H3,(H2,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	840	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205253 (CHEMBL3947936) Show SMILES CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1cccc(c1)C(O)=O Show InChI InChI=1S/C24H22N2O2/c1-2-6-23-25-21-9-3-4-10-22(21)26(23)16-17-11-13-18(14-12-17)19-7-5-8-20(15-19)24(27)28/h3-5,7-15H,2,6,16H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.24E+3	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50205254 (CHEMBL3958255) Show SMILES CCCCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C27H28N2O2/c1-2-3-4-5-14-26-28-24-12-8-9-13-25(24)29(26)19-20-15-17-21(18-16-20)22-10-6-7-11-23(22)27(30)31/h6-13,15-18H,2-5,14,19H2,1H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
Universit£t Innsbruck Curated by ChEMBL					Assay Description Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assay				Eur J Med Chem 124: 138-152 (2016) Article DOI: 10.1016/j.ejmech.2016.08.027 BindingDB Entry DOI: 10.7270/Q26D5W08
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232203 (CHEMBL4104178) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1ccc(O)cc1 Show InChI InChI=1S/C30H26N2O3/c1-2-5-29-31-27-17-14-23(21-12-15-24(33)16-13-21)18-28(27)32(29)19-20-8-10-22(11-9-20)25-6-3-4-7-26(25)30(34)35/h3-4,6-18,33H,2,5,19H2,1H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232204 (CHEMBL4105094) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1cccc(O)c1 Show InChI InChI=1S/C30H26N2O3/c1-2-6-29-31-27-16-15-23(22-7-5-8-24(33)17-22)18-28(27)32(29)19-20-11-13-21(14-12-20)25-9-3-4-10-26(25)30(34)35/h3-5,7-18,33H,2,6,19H2,1H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.09E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232205 (CHEMBL4080865) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C30H25ClN2O2/c1-2-5-29-32-27-17-14-23(21-12-15-24(31)16-13-21)18-28(27)33(29)19-20-8-10-22(11-9-20)25-6-3-4-7-26(25)30(34)35/h3-4,6-18H,2,5,19H2,1H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232206 (CHEMBL4090484) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C30H25ClN2O2/c1-2-6-29-32-27-16-15-23(22-7-5-8-24(31)17-22)18-28(27)33(29)19-20-11-13-21(14-12-20)25-9-3-4-10-26(25)30(34)35/h3-5,7-18H,2,6,19H2,1H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	770	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50043280 (4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...) Show SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1nc2ccccc2n1C Show InChI InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	4.97E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50103521 (Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...) Show SMILES CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1 Show InChI InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50324046 (4'-[(6-(Hydroxy(phenyl)methyl)-2-propyl-1H-benzo[d...) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(O)c1ccccc1 Show InChI InChI=1S/C31H28N2O3/c1-2-8-29-32-27-18-17-24(30(34)23-9-4-3-5-10-23)19-28(27)33(29)20-21-13-15-22(16-14-21)25-11-6-7-12-26(25)31(35)36/h3-7,9-19,30,34H,2,8,20H2,1H3,(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50324044 (4'-[(6-(Phenylcarbonyl)-2-propyl-1H-benzo[d]imidaz...) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)c1ccccc1 Show InChI InChI=1S/C31H26N2O3/c1-2-8-29-32-27-18-17-24(30(34)23-9-4-3-5-10-23)19-28(27)33(29)20-21-13-15-22(16-14-21)25-11-6-7-12-26(25)31(35)36/h3-7,9-19H,2,8,20H2,1H3,(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232207 (CHEMBL4096160) Show SMILES CCCc1nc2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C31H28N2O3/c1-3-6-30-32-28-19-24(22-13-16-25(36-2)17-14-22)15-18-29(28)33(30)20-21-9-11-23(12-10-21)26-7-4-5-8-27(26)31(34)35/h4-5,7-19H,3,6,20H2,1-2H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232209 (CHEMBL4096447) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C31H28N2O3/c1-3-6-30-32-28-18-15-24(22-13-16-25(36-2)17-14-22)19-29(28)33(30)20-21-9-11-23(12-10-21)26-7-4-5-8-27(26)31(34)35/h4-5,7-19H,3,6,20H2,1-2H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232215 (CHEMBL4101759) Show SMILES CCCc1nc2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C30H25ClN2O2/c1-2-5-29-32-27-18-23(21-12-15-24(31)16-13-21)14-17-28(27)33(29)19-20-8-10-22(11-9-20)25-6-3-4-7-26(25)30(34)35/h3-4,6-18H,2,5,19H2,1H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232216 (CHEMBL4078402) Show SMILES CCCc1nc2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1ccccc1Cl Show InChI InChI=1S/C30H25ClN2O2/c1-2-7-29-32-27-18-22(24-9-5-6-11-26(24)31)16-17-28(27)33(29)19-20-12-14-21(15-13-20)23-8-3-4-10-25(23)30(34)35/h3-6,8-18H,2,7,19H2,1H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	930	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232211 (CHEMBL4066489) Show SMILES CCCc1nc2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1cccc(O)c1 Show InChI InChI=1S/C30H26N2O3/c1-2-6-29-31-27-18-23(22-7-5-8-24(33)17-22)15-16-28(27)32(29)19-20-11-13-21(14-12-20)25-9-3-4-10-26(25)30(34)35/h3-5,7-18,33H,2,6,19H2,1H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232210 (CHEMBL4078107) Show SMILES CCCc1nc2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1cccc(OC)c1 Show InChI InChI=1S/C31H28N2O3/c1-3-7-30-32-28-19-24(23-8-6-9-25(18-23)36-2)16-17-29(28)33(30)20-21-12-14-22(15-13-21)26-10-4-5-11-27(26)31(34)35/h4-6,8-19H,3,7,20H2,1-2H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232214 (CHEMBL4094026) Show SMILES CCCc1nc2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1ccc(O)cc1 Show InChI InChI=1S/C30H26N2O3/c1-2-5-29-31-27-18-23(21-12-15-24(33)16-13-21)14-17-28(27)32(29)19-20-8-10-22(11-9-20)25-6-3-4-7-26(25)30(34)35/h3-4,6-18,33H,2,5,19H2,1H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50232212 (CHEMBL4086261) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1cccc(OC)c1 Show InChI InChI=1S/C31H28N2O3/c1-3-7-30-32-28-17-16-24(23-8-6-9-25(18-23)36-2)19-29(28)33(30)20-21-12-14-22(15-13-21)26-10-4-5-11-27(26)31(34)35/h4-6,8-19H,3,7,20H2,1-2H3,(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50324039 (4'-[(2-Propyl-1H-benzo[d]imidazol-1-yl)methyl]biph...) Show SMILES CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C24H22N2O2/c1-2-7-23-25-21-10-5-6-11-22(21)26(23)16-17-12-14-18(15-13-17)19-8-3-4-9-20(19)24(27)28/h3-6,8-15H,2,7,16H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.44E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assay				Eur J Med Chem 126: 590-603 (2017) Article DOI: 10.1016/j.ejmech.2016.11.051 BindingDB Entry DOI: 10.7270/Q2N87D1B
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50207272 (CHEMBL3960906) Show SMILES O=C(CN1c2ccccc2Sc2ccccc12)NNC(=S)NCc1ccccc1 Show InChI InChI=1S/C22H20N4OS2/c27-21(24-25-22(28)23-14-16-8-2-1-3-9-16)15-26-17-10-4-6-12-19(17)29-20-13-7-5-11-18(20)26/h1-13H,14-15H2,(H,24,27)(H2,23,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of Fluoromone from GST-tagged recombinant human PPARgamma ligand binding domain by LanthaScreen TR-FRET assay				Eur J Med Chem 124: 49-62 (2016) Article DOI: 10.1016/j.ejmech.2016.07.072 BindingDB Entry DOI: 10.7270/Q2K939G4
					More data for this Ligand-Target Pair