Compile Data Set for Download or QSAR

Found 94 hits with Last Name = 'ohtake' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402251 (CHEMBL2204791) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)C(C)(C)C Show InChI InChI=1S/C13H17N3O2S/c1-7-10(19-12(15-7)16-8(2)17)9-6-14-11(18-9)13(3,4)5/h6H,1-5H3,(H,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402256 (CHEMBL2204786) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)-c1cccnc1 Show InChI InChI=1S/C14H12N4O2S/c1-8-12(21-14(17-8)18-9(2)19)11-7-16-13(20-11)10-4-3-5-15-6-10/h3-7H,1-2H3,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402251 (CHEMBL2204791) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)C(C)(C)C Show InChI InChI=1S/C13H17N3O2S/c1-7-10(19-12(15-7)16-8(2)17)9-6-14-11(18-9)13(3,4)5/h6H,1-5H3,(H,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402265 (CHEMBL2164280 | US8802861, 1) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cccc(c2)C(O)=O)n1 Show InChI InChI=1S/C16H14N4O3S2/c1-8-13(25-16(17-8)18-9(2)21)12-7-24-15(20-12)19-11-5-3-4-10(6-11)14(22)23/h3-7H,1-2H3,(H,19,20)(H,22,23)(H,17,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444445 (CHEMBL3092373) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CC(C)(C)CO)no1 Show InChI InChI=1S/C13H18N4O3S/c1-7-10(21-12(14-7)15-8(2)19)11-16-9(17-20-11)5-13(3,4)6-18/h18H,5-6H2,1-4H3,(H,14,15,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402254 (CHEMBL2204788) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(CC(F)(F)F)o1 Show InChI InChI=1S/C11H10F3N3O2S/c1-5-9(20-10(16-5)17-6(2)18)7-4-15-8(19-7)3-11(12,13)14/h4H,3H2,1-2H3,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402266 (CHEMBL2204778) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)S(C)(=O)=O Show InChI InChI=1S/C10H11N3O4S2/c1-5-8(18-9(12-5)13-6(2)14)7-4-11-10(17-7)19(3,15)16/h4H,1-3H3,(H,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402260 (CHEMBL2203302) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Nc2cccnc2)o1 Show InChI InChI=1S/C14H13N5O2S/c1-8-12(22-14(17-8)18-9(2)20)11-7-16-13(21-11)19-10-4-3-5-15-6-10/h3-7H,1-2H3,(H,16,19)(H,17,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402264 (CHEMBL2204779) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Nc2cccc(c2)C(O)=O)o1 Show InChI InChI=1S/C16H14N4O4S/c1-8-13(25-16(18-8)19-9(2)21)12-7-17-15(24-12)20-11-5-3-4-10(6-11)14(22)23/h3-7H,1-2H3,(H,17,20)(H,22,23)(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444447 (CHEMBL3092365) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(no1)C(C)(C)C Show InChI InChI=1S/C12H16N4O2S/c1-6-8(19-11(13-6)14-7(2)17)9-15-10(16-18-9)12(3,4)5/h1-5H3,(H,13,14,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402268 (CHEMBL2204794) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)N1CCCC(O)C1 Show InChI InChI=1S/C14H18N4O3S/c1-8-12(22-13(16-8)17-9(2)19)11-6-15-14(21-11)18-5-3-4-10(20)7-18/h6,10,20H,3-5,7H2,1-2H3,(H,16,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50402251 (CHEMBL2204791) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)C(C)(C)C Show InChI InChI=1S/C13H17N3O2S/c1-7-10(19-12(15-7)16-8(2)17)9-6-14-11(18-9)13(3,4)5/h6H,1-5H3,(H,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402257 (CHEMBL2204785) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Sc2cccnc2)o1 Show InChI InChI=1S/C14H12N4O2S2/c1-8-12(22-13(17-8)18-9(2)19)11-7-16-14(20-11)21-10-4-3-5-15-6-10/h3-7H,1-2H3,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444444 (CHEMBL3092375) Show SMILES CC(O)C(C)(C)Cc1noc(n1)-c1sc(NC(C)=O)nc1C Show InChI InChI=1S/C14H20N4O3S/c1-7-11(22-13(15-7)16-9(3)20)12-17-10(18-21-12)6-14(4,5)8(2)19/h8,19H,6H2,1-5H3,(H,15,16,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402267 (CHEMBL2204777) Show SMILES CSc1ncc(o1)-c1sc(NC(C)=O)nc1C Show InChI InChI=1S/C10H11N3O2S2/c1-5-8(7-4-11-10(15-7)16-3)17-9(12-5)13-6(2)14/h4H,1-3H3,(H,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402261 (CHEMBL2204782) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Nc2ccc(Cl)nc2)o1 Show InChI InChI=1S/C14H12ClN5O2S/c1-7-12(23-14(18-7)19-8(2)21)10-6-17-13(22-10)20-9-3-4-11(15)16-5-9/h3-6H,1-2H3,(H,17,20)(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402269 (CHEMBL2204793) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)N1CCOCC1 Show InChI InChI=1S/C13H16N4O3S/c1-8-11(21-12(15-8)16-9(2)18)10-7-14-13(20-10)17-3-5-19-6-4-17/h7H,3-6H2,1-2H3,(H,15,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402252 (CHEMBL2204790) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)C(C)(C)O Show InChI InChI=1S/C12H15N3O3S/c1-6-9(19-11(14-6)15-7(2)16)8-5-13-10(18-8)12(3,4)17/h5,17H,1-4H3,(H,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444446 (CHEMBL3092367) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CC(F)(F)F)no1 Show InChI InChI=1S/C10H9F3N4O2S/c1-4-7(20-9(14-4)15-5(2)18)8-16-6(17-19-8)3-10(11,12)13/h3H2,1-2H3,(H,14,15,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444443 (CHEMBL3092376) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(no1)N1CCCC(O)C1 Show InChI InChI=1S/C13H17N5O3S/c1-7-10(22-13(14-7)15-8(2)19)11-16-12(17-21-11)18-5-3-4-9(20)6-18/h9,20H,3-6H2,1-2H3,(H,14,15,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50402254 (CHEMBL2204788) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(CC(F)(F)F)o1 Show InChI InChI=1S/C11H10F3N3O2S/c1-5-9(20-10(16-5)17-6(2)18)7-4-15-8(19-7)3-11(12,13)14/h4H,3H2,1-2H3,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50402256 (CHEMBL2204786) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)-c1cccnc1 Show InChI InChI=1S/C14H12N4O2S/c1-8-12(21-14(17-8)18-9(2)19)11-7-16-13(20-11)10-4-3-5-15-6-10/h3-7H,1-2H3,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402270 (CHEMBL2204792) Show SMILES CN(C)c1ncc(o1)-c1sc(NC(C)=O)nc1C Show InChI InChI=1S/C11H14N4O2S/c1-6-9(18-10(13-6)14-7(2)16)8-5-12-11(17-8)15(3)4/h5H,1-4H3,(H,13,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444453 (CHEMBL3092369) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(no1)C(C)(C)CO Show InChI InChI=1S/C12H16N4O3S/c1-6-8(20-11(13-6)14-7(2)18)9-15-10(16-19-9)12(3,4)5-17/h17H,5H2,1-4H3,(H,13,14,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444440 (CHEMBL3092362) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(no1)C1CCOC1 Show InChI InChI=1S/C12H14N4O3S/c1-6-9(20-12(13-6)14-7(2)17)11-15-10(16-19-11)8-3-4-18-5-8/h8H,3-5H2,1-2H3,(H,13,14,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Mus musculus (Mouse))	BDBM50402256 (CHEMBL2204786) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)-c1cccnc1 Show InChI InChI=1S/C14H12N4O2S/c1-8-12(21-14(17-8)18-9(2)19)11-7-16-13(20-11)10-4-3-5-15-6-10/h3-7H,1-2H3,(H,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-indu...				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444450 (CHEMBL3092372) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(no1)C(C)(C)CCO Show InChI InChI=1S/C13H18N4O3S/c1-7-9(21-12(14-7)15-8(2)19)10-16-11(17-20-10)13(3,4)5-6-18/h18H,5-6H2,1-4H3,(H,14,15,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444452 (CHEMBL3092370) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CC(C)(C)O)no1 Show InChI InChI=1S/C12H16N4O3S/c1-6-9(20-11(13-6)14-7(2)17)10-15-8(16-19-10)5-12(3,4)18/h18H,5H2,1-4H3,(H,13,14,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444448 (CHEMBL3092361) Show SMILES COCC(C)(C)Cc1noc(n1)-c1sc(NC(C)=O)nc1C Show InChI InChI=1S/C14H20N4O3S/c1-8-11(22-13(15-8)16-9(2)19)12-17-10(18-21-12)6-14(3,4)7-20-5/h6-7H2,1-5H3,(H,15,16,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444441 (CHEMBL3092366) Show SMILES Cc1nc(N)sc1-c1nc(no1)C(C)(C)C Show InChI InChI=1S/C10H14N4OS/c1-5-6(16-9(11)12-5)7-13-8(14-15-7)10(2,3)4/h1-4H3,(H2,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444442 (CHEMBL3092364) Show SMILES Cc1nc(N)sc1-c1cnc(o1)C(C)(C)C Show InChI InChI=1S/C11H15N3OS/c1-6-8(16-10(12)14-6)7-5-13-9(15-7)11(2,3)4/h5H,1-4H3,(H2,12,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Mus musculus (Mouse))	BDBM50402254 (CHEMBL2204788) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(CC(F)(F)F)o1 Show InChI InChI=1S/C11H10F3N3O2S/c1-5-9(20-10(16-5)17-6(2)18)7-4-15-8(19-7)3-11(12,13)14/h4H,3H2,1-2H3,(H,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-indu...				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402259 (CHEMBL2204783) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Cc2cccnc2)o1 Show InChI InChI=1S/C15H14N4O2S/c1-9-14(22-15(18-9)19-10(2)20)12-8-17-13(21-12)6-11-4-3-5-16-7-11/h3-5,7-8H,6H2,1-2H3,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444439 (CHEMBL3092363) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(no1)N1CCOCC1 Show InChI InChI=1S/C12H15N5O3S/c1-7-9(21-12(13-7)14-8(2)18)10-15-11(16-20-10)17-3-5-19-6-4-17/h3-6H2,1-2H3,(H,13,14,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50402260 (CHEMBL2203302) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Nc2cccnc2)o1 Show InChI InChI=1S/C14H13N5O2S/c1-8-12(22-14(17-8)18-9(2)20)11-7-16-13(21-11)19-10-4-3-5-15-6-10/h3-7H,1-2H3,(H,16,19)(H,17,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50402257 (CHEMBL2204785) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Sc2cccnc2)o1 Show InChI InChI=1S/C14H12N4O2S2/c1-8-12(22-13(17-8)18-9(2)19)11-7-16-14(20-11)21-10-4-3-5-15-6-10/h3-7H,1-2H3,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Mus musculus (Mouse))	BDBM50402251 (CHEMBL2204791) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)C(C)(C)C Show InChI InChI=1S/C13H17N3O2S/c1-7-10(19-12(15-7)16-8(2)17)9-6-14-11(18-9)13(3,4)5/h6H,1-5H3,(H,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-indu...				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402258 (CHEMBL2204784) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Oc2cccnc2)o1 Show InChI InChI=1S/C14H12N4O3S/c1-8-12(22-13(17-8)18-9(2)19)11-7-16-14(21-11)20-10-4-3-5-15-6-10/h3-7H,1-2H3,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444451 (CHEMBL3092371) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CCCO)no1 Show InChI InChI=1S/C11H14N4O3S/c1-6-9(19-11(12-6)13-7(2)17)10-14-8(15-18-10)4-3-5-16/h16H,3-5H2,1-2H3,(H,12,13,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Mus musculus (Mouse))	BDBM50444444 (CHEMBL3092375) Show SMILES CC(O)C(C)(C)Cc1noc(n1)-c1sc(NC(C)=O)nc1C Show InChI InChI=1S/C14H20N4O3S/c1-7-11(22-13(15-7)16-9(3)20)12-17-10(18-21-12)6-14(4,5)8(2)19/h8,19H,6H2,1-5H3,(H,15,16,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as C5a-mediated PKB/Akt phosphorylation preincubated for 30 mins followed by C5a stimulation...				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444454 (CHEMBL3092368) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CCO)no1 Show InChI InChI=1S/C10H12N4O3S/c1-5-8(18-10(11-5)12-6(2)16)9-13-7(3-4-15)14-17-9/h15H,3-4H2,1-2H3,(H,11,12,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402253 (CHEMBL2204789) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(CO)o1 Show InChI InChI=1S/C10H11N3O3S/c1-5-9(7-3-11-8(4-14)16-7)17-10(12-5)13-6(2)15/h3,14H,4H2,1-2H3,(H,12,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402255 (CHEMBL2204787) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(C)o1 Show InChI InChI=1S/C10H11N3O2S/c1-5-9(8-4-11-7(3)15-8)16-10(12-5)13-6(2)14/h4H,1-3H3,(H,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Mus musculus (Mouse))	BDBM50444445 (CHEMBL3092373) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CC(C)(C)CO)no1 Show InChI InChI=1S/C13H18N4O3S/c1-7-10(21-12(14-7)15-8(2)19)11-16-9(17-20-11)5-13(3,4)6-18/h18H,5-6H2,1-4H3,(H,14,15,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as C5a-mediated PKB/Akt phosphorylation preincubated for 30 mins followed by C5a stimulation...				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50402266 (CHEMBL2204778) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)S(C)(=O)=O Show InChI InChI=1S/C10H11N3O4S2/c1-5-8(18-9(12-5)13-6(2)14)7-4-11-10(17-7)19(3,15)16/h4H,1-3H3,(H,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444449 (CHEMBL3092374) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CCC(C)(C)O)no1 Show InChI InChI=1S/C13H18N4O3S/c1-7-10(21-12(14-7)15-8(2)18)11-16-9(17-20-11)5-6-13(3,4)19/h19H,5-6H2,1-4H3,(H,14,15,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Mus musculus (Mouse))	BDBM50402266 (CHEMBL2204778) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)S(C)(=O)=O Show InChI InChI=1S/C10H11N3O4S2/c1-5-8(18-9(12-5)13-6(2)14)7-4-11-10(17-7)19(3,15)16/h4H,1-3H3,(H,12,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-indu...				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50402263 (CHEMBL2204780) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Cc2cccc(c2)C(O)=O)o1 Show InChI InChI=1S/C17H15N3O4S/c1-9-15(25-17(19-9)20-10(2)21)13-8-18-14(24-13)7-11-4-3-5-12(6-11)16(22)23/h3-6,8H,7H2,1-2H3,(H,22,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation counting				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Mus musculus (Mouse))	BDBM50444447 (CHEMBL3092365) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(no1)C(C)(C)C Show InChI InChI=1S/C12H16N4O2S/c1-6-8(19-11(13-6)14-7(2)17)9-15-10(16-18-9)12(3,4)5/h1-5H3,(H,13,14,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	231	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as C5a-mediated PKB/Akt phosphorylation preincubated for 30 mins followed by C5a stimulation...				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Mus musculus (Mouse))	BDBM50402268 (CHEMBL2204794) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(o1)N1CCCC(O)C1 Show InChI InChI=1S/C14H18N4O3S/c1-8-12(22-13(16-8)17-9(2)19)11-6-15-14(21-11)18-5-3-4-10(20)7-18/h6,10,20H,3-5,7H2,1-2H3,(H,16,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-indu...				Bioorg Med Chem Lett 22: 7534-8 (2012) Article DOI: 10.1016/j.bmcl.2012.10.028 BindingDB Entry DOI: 10.7270/Q27W6DBG
					More data for this Ligand-Target Pair

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