Compile Data Set for Download or QSAR

Found 828 hits with Last Name = 'oliva' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643722 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1n[nH]c2=O |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643732 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-1,4-dimet...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c(C)nnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Acetylcholinesterase (Homo sapiens (Human))	BDBM50556952 (CHEMBL4754487) Show SMILES COc1cc(CNC(=O)CCCCCCNc2c3C4CC(Cc3nc3cc(Cl)ccc23)C=C(C)C4)ccc1O |t:34,TLB:23:22:19:34.31.32,THB:16:17:19:34.31.32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Mixed-type inhibition of recombinant human AChE assessed as inhibition constant using acetylthiocholine iodide as substrate by Cornish-Bowden plot an...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01775 BindingDB Entry DOI: 10.7270/Q2K077XJ
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643720 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cccnn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643728 ((4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-1,4-d...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Br)ccc2-n2c(C)nnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643750 ((4S)-7-chloro-6-(2,6-difluorophenyl)-8-iodo-1,4-di...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(I)ccc2-n2c(C)nnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643717 ((4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-4-met...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Br)ccc2-n2cnnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50556952 (CHEMBL4754487) Show SMILES COc1cc(CNC(=O)CCCCCCNc2c3C4CC(Cc3nc3cc(Cl)ccc23)C=C(C)C4)ccc1O |t:34,TLB:23:22:19:34.31.32,THB:16:17:19:34.31.32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Mixed-type inhibition of recombinant human AChE assessed as dissociation constant for protein-substrate-compound complex using acetylthiocholine iodi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01775 BindingDB Entry DOI: 10.7270/Q2K077XJ
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643749 (US20240002393, Example 101 | [(4R)-8-bromo-7-chlor...) Show SMILES Cc1nnc2[C@H](CO)N=C(c3c(F)cccc3F)c3c(Cl)c(Br)ccc3-n12 |r,t:8| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643719 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cnn(C)c1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643718 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1ccncn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643715 ((4S)-8-bromo-7-chloro-6-(2-fluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2ccccc2F)c2c(Cl)c(Br)ccc2-n2c1nnc2-c1cccnn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643736 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1ccc(C)nn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643743 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1ccnc(C)n1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643740 ((4S)-7-chloro-6-(2,6-difluorophenyl)-1,4-dimethyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ccc2-n2c(C)nnc12)C(F)(F)F |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643742 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cc(C)ncn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643726 ((4S)-7-bromo-8-chloro-6-(2,6-difluorophenyl)-4-met...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Br)c(Cl)ccc2-n2c1nnc2-c1cccnn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643755 ((4S)-7-chloro-6-(2,6-difluorophenyl)-1-ethyl-4-met...) Show SMILES CCc1nnc2[C@H](C)N=C(c3c(F)cccc3F)c3c(Cl)c(ccc3-n12)C(F)(F)F |r,t:8| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643737 (5-[(4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-meth...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cc(C)no1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643745 ((4S)-7-chloro-6-(2,6-difluorophenyl)-1,4,8-trimeth...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(C)ccc2-n2c(C)nnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643727 ((4S)-7-bromo-8-chloro-6-(2,6-difluorophenyl)-4-met...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Br)c(Cl)ccc2-n2c1nnc2-c1ccncn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643713 ((4S)-8-bromo-7-chloro-6-(2-fluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2ccccc2F)c2c(Cl)c(Br)ccc2-n2cnnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643733 ((4S)-8-bromo-7-chloro-1-cyclopropyl-6-(3-fluoro-2-...) Show SMILES C[C@@H]1N=C(c2ncccc2F)c2c(Cl)c(Br)ccc2-n2c(nnc12)C1CC1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643714 (8-bromo-7-chloro-6-(2,6-difluorophenyl)-4H-[1,2,4]...) Show SMILES OC1N=C(c2c(F)cccc2F)c2c(Cl)c(Br)ccc2-n2cnnc12 |t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643730 ((4S)-7-bromo-8-chloro-6-(2,6-difluorophenyl)-1,4-d...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Br)c(Cl)ccc2-n2c(C)nnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50587822 (CHEMBL5186915) Show SMILES [H][C@@]12CN(Cc3ccccc3)C[C@@]1([H])n1nnc(c1CO2)-c1cccc(F)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00244 BindingDB Entry DOI: 10.7270/Q2J1074M
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643744 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-1-(2,6-di...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cc(C)nc(C)n1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643754 ((4S)-7-chloro-6-(2,6-difluorophenyl)-4-methyl-8-(t...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ccc2-n2cnnc12)C(F)(F)F |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643719 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cnn(C)c1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643741 ((4S)-7-chloro-8-(1,1-difluoroethyl)-6-(2,6-difluor...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ccc2-n2c(C)nnc12)C(C)(F)F |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643747 ((4S)-7-chloro-8-(difluoromethyl)-6-(2,6-difluoroph...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ccc2-n2c(C)nnc12)C(F)F |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643724 ((4S)-7,8-dichloro-6-(3-fluoro-2-pyridyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2ncccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cnn(C)c1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643735 ((4S)-8-bromo-7-chloro-6-(3-fluoro-2-pyridyl)-1,4-d...) Show SMILES C[C@@H]1N=C(c2ncccc2F)c2c(Cl)c(Br)ccc2-n2c(C)nnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643748 ((4R)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-4-(me...) Show SMILES COC[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Br)ccc2-n2c(C)nnc12 |r,t:4| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643729 ((4S)-7-bromo-8-chloro-6-(2,6-difluorophenyl)-4-met...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Br)c(Cl)ccc2-n2c1nnc2-c1cnn(C)c1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643738 ((4S)-7-bromo-8-chloro-6-(2,6-difluorophenyl)-4-met...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Br)c(Cl)ccc2-n2c1nnc2-c1ccc(C)nn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643756 ((4S)-7-chloro-6-(2,6-difluorophenyl)-8-ethyl-1,4-d...) Show SMILES CCc1ccc-2c(c1Cl)C(=N[C@@H](C)c1nnc(C)n-21)c1c(F)cccc1F |r,c:10| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643720 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cccnn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM436444 ((S)-9-methyl-6-(3-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1cccc(c1)N1CCN(C)c2nc(SC)ncc2C1=O)c1cccs1 |r| Show InChI InChI=1S/C23H27N5O2S2/c1-24-10-9-19(20-8-5-13-32-20)30-17-7-4-6-16(14-17)28-12-11-27(2)21-18(22(28)29)15-25-23(26-21)31-3/h4-8,13-15,19,24H,9-12H2,1-3H3/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-nisoxetine from human NET expressed in HEK293 cell membranes incubated for 60 mins by scintillation counting method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01867 BindingDB Entry DOI: 10.7270/Q2JW8JKT
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643731 ((4S)-7-bromo-8-chloro-6-(2,6-difluorophenyl)-4-met...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Br)c(Cl)ccc2-n2c1nnc2-c1ccn(C)n1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643753 (US20240002393, Example 106 | [(4R)-7-chloro-6-(2,6...) Show SMILES Cc1nnc2[C@H](CO)N=C(c3c(F)cccc3F)c3c(Cl)c(ccc3-n12)C(F)(F)F |r,t:8| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643739 ((4S)-7-bromo-8-chloro-6-(2,6-difluorophenyl)-4-met...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Br)c(Cl)ccc2-n2c1n[nH]c2=O |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643736 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1ccc(C)nn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643746 ((4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-4-eth...) Show SMILES CC[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Br)ccc2-n2c(C)nnc12 |r,t:3| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643720 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cccnn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643717 ((4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-4-met...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Br)ccc2-n2cnnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643728 ((4S)-8-bromo-7-chloro-6-(2,6-difluorophenyl)-1,4-d...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Br)ccc2-n2c(C)nnc12 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643751 (US20240002393, Example 103 | [(4S)-7-chloro-6-(2,6...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(ccc2-n2c(CO)nnc12)C(F)(F)F |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643721 ((4S)-7,8-dichloro-6-(3-fluoro-2-pyridyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2ncccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1cccnn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1 (Homo sapiens (Human))	BDBM643718 ((4S)-7,8-dichloro-6-(2,6-difluorophenyl)-4-methyl-...) Show SMILES C[C@@H]1N=C(c2c(F)cccc2F)c2c(Cl)c(Cl)ccc2-n2c1nnc2-c1ccncn1 |r,t:2| Show InChI	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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