BindingDB PrimarySearch

Found 15 hits with Last Name = 'padhye' and Initial = 's'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50038649 (2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of 5-LOX (unknown origin) by ELISA				Bioorg Med Chem Lett 24: 317-24 (2013) Article DOI: 10.1016/j.bmcl.2013.11.015 BindingDB Entry DOI: 10.7270/Q2BK1DTP
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50491246 (Darbufelone) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of sheep placental COX-2 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of stan...				Bioorg Med Chem 21: 2551-9 (2013) Article DOI: 10.1016/j.bmc.2013.02.033 BindingDB Entry DOI: 10.7270/Q2H41VBV
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50444817 (CHEMBL3099218) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of 5-LOX (unknown origin) by ELISA				Bioorg Med Chem Lett 24: 317-24 (2013) Article DOI: 10.1016/j.bmcl.2013.11.015 BindingDB Entry DOI: 10.7270/Q2BK1DTP
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50444814 (CHEMBL3099221) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of 5-LOX (unknown origin) by ELISA				Bioorg Med Chem Lett 24: 317-24 (2013) Article DOI: 10.1016/j.bmcl.2013.11.015 BindingDB Entry DOI: 10.7270/Q2BK1DTP
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50444815 (CHEMBL3099220) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of 5-LOX (unknown origin) by ELISA				Bioorg Med Chem Lett 24: 317-24 (2013) Article DOI: 10.1016/j.bmcl.2013.11.015 BindingDB Entry DOI: 10.7270/Q2BK1DTP
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50491247 (CHEMBL527577 \| TCMDC-123490) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of sheep placental COX-2 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of stan...				Bioorg Med Chem 21: 2551-9 (2013) Article DOI: 10.1016/j.bmc.2013.02.033 BindingDB Entry DOI: 10.7270/Q2H41VBV
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50444816 (CHEMBL3099219) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of 5-LOX (unknown origin) by ELISA				Bioorg Med Chem Lett 24: 317-24 (2013) Article DOI: 10.1016/j.bmcl.2013.11.015 BindingDB Entry DOI: 10.7270/Q2BK1DTP
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50491244 (CHEMBL2380930) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of sheep placental COX-2 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of stan...				Bioorg Med Chem 21: 2551-9 (2013) Article DOI: 10.1016/j.bmc.2013.02.033 BindingDB Entry DOI: 10.7270/Q2H41VBV
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50491245 (CHEMBL2380929) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of sheep placental COX-2 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of stan...				Bioorg Med Chem 21: 2551-9 (2013) Article DOI: 10.1016/j.bmc.2013.02.033 BindingDB Entry DOI: 10.7270/Q2H41VBV
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50199450 (1-(quinolin-2-ylmethylene)thiosemicarbazide \| 2-(q...) Show SMILES NC(=S)NN=Cc1ccc2ccccc2n1 \|w:5.5\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity in rabbit 20S proteasome				J Med Chem 49: 7242-6 (2006) Article DOI: 10.1021/jm060712l BindingDB Entry DOI: 10.7270/Q2RV0NCV
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50491245 (CHEMBL2380929) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of ram seminal vesicle COX-1 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of ...				Bioorg Med Chem 21: 2551-9 (2013) Article DOI: 10.1016/j.bmc.2013.02.033 BindingDB Entry DOI: 10.7270/Q2H41VBV
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50491246 (Darbufelone) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of ram seminal vesicle COX-1 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of ...				Bioorg Med Chem 21: 2551-9 (2013) Article DOI: 10.1016/j.bmc.2013.02.033 BindingDB Entry DOI: 10.7270/Q2H41VBV
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50491244 (CHEMBL2380930) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of ram seminal vesicle COX-1 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of ...				Bioorg Med Chem 21: 2551-9 (2013) Article DOI: 10.1016/j.bmc.2013.02.033 BindingDB Entry DOI: 10.7270/Q2H41VBV
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50491247 (CHEMBL527577 \| TCMDC-123490) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by ChEMBL					Assay Description Inhibition of ram seminal vesicle COX-1 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of ...				Bioorg Med Chem 21: 2551-9 (2013) Article DOI: 10.1016/j.bmc.2013.02.033 BindingDB Entry DOI: 10.7270/Q2H41VBV
Medical University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM19459 (5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...) Show SMILES Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pune Curated by ChEMBL					Assay Description Inhibition of Akt by fluorescence polarization assay				J Med Chem 49: 3800-8 (2006) Article DOI: 10.1021/jm051068y BindingDB Entry DOI: 10.7270/Q2QZ2BRJ
University of Pune Curated by ChEMBL					More data for this Ligand-Target Pair