Compile Data Set for Download or QSAR

Found 33 hits with Last Name = 'paul' and Initial = 'cd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Homo sapiens (Human))	BDBM576396 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-1,3-benzothiazole...) Show SMILES Cc1n[nH]c(C)c1-c1cccc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576414 (7-(3,5-dimethyl-1 H-pyrazol-4-yl)[1,3]thiazolo[5,4...) Show SMILES Cc1n[nH]c(C)c1-c1ccnc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576397 (7-(3,5-dimethyl-1H-pyrazol-4-yl)-1,3-benzothiazole...) Show SMILES Cc1n[nH]c(C)c1-c1cccc2ncsc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576397 (7-(3,5-dimethyl-1H-pyrazol-4-yl)-1,3-benzothiazole...) Show SMILES Cc1n[nH]c(C)c1-c1cccc2ncsc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576398 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-7- ethyl-1,3-ben...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(C)c2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576398 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-7- ethyl-1,3-ben...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(C)c2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576399 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-7-(trifluoro eth...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(c2scnc12)C(F)(F)F |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,;-4.98,1.48,;-6.12,.44,;-5.3,2.98,;-4.66,-.03,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576399 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-7-(trifluoro eth...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(c2scnc12)C(F)(F)F |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,;-4.98,1.48,;-6.12,.44,;-5.3,2.98,;-4.66,-.03,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576400 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-1,3-benzothiazol...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(C#N)c2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-6.44,1.95,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576400 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-1,3-benzothiazol...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(C#N)c2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-6.44,1.95,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576401 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-2-methyl-1,3-ben...) Show SMILES Cc1nc2c(cccc2s1)-c1c(C)n[nH]c1C |(-3.67,-4.46,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;.88,-.43,;2.13,.48,;2.13,2.02,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576401 (4-(3,5-dimethyl-1 H-pyrazol-4-yl)-2-methyl-1,3-ben...) Show SMILES Cc1nc2c(cccc2s1)-c1c(C)n[nH]c1C |(-3.67,-4.46,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;.88,-.43,;2.13,.48,;2.13,2.02,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	574	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576402 (4-(1,3-benzothiazol-4-yl)-5-methyl-1 H-pyrazole-3-...) Show SMILES Cc1[nH]nc(C#N)c1-c1cccc2scnc12 |(.45,-3.14,;1.36,-1.89,;2.9,-1.89,;3.37,-.43,;2.13,.48,;2.13,2.02,;2.13,3.56,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576402 (4-(1,3-benzothiazol-4-yl)-5-methyl-1 H-pyrazole-3-...) Show SMILES Cc1[nH]nc(C#N)c1-c1cccc2scnc12 |(.45,-3.14,;1.36,-1.89,;2.9,-1.89,;3.37,-.43,;2.13,.48,;2.13,2.02,;2.13,3.56,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576403 (5-methyl-4-(7-methyl-1,3-benzothiazol-4-yl)-1H-pyr...) Show SMILES Cc1[nH]nc(C#N)c1-c1ccc(C)c2scnc12 |(.45,-3.14,;1.36,-1.89,;2.9,-1.89,;3.37,-.43,;2.13,.48,;2.13,2.02,;2.13,3.56,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576403 (5-methyl-4-(7-methyl-1,3-benzothiazol-4-yl)-1H-pyr...) Show SMILES Cc1[nH]nc(C#N)c1-c1ccc(C)c2scnc12 |(.45,-3.14,;1.36,-1.89,;2.9,-1.89,;3.37,-.43,;2.13,.48,;2.13,2.02,;2.13,3.56,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576404 (5-methyl-4-[7-(trifluoromethyl)-1,3-benzothiazol-4...) Show SMILES Cc1[nH]nc(C#N)c1-c1ccc(c2scnc12)C(F)(F)F |(.45,-3.14,;1.36,-1.89,;2.9,-1.89,;3.37,-.43,;2.13,.48,;2.13,2.02,;2.13,3.56,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,;-4.98,1.48,;-6.12,.44,;-5.3,2.98,;-4.66,-.03,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576404 (5-methyl-4-[7-(trifluoromethyl)-1,3-benzothiazol-4...) Show SMILES Cc1[nH]nc(C#N)c1-c1ccc(c2scnc12)C(F)(F)F |(.45,-3.14,;1.36,-1.89,;2.9,-1.89,;3.37,-.43,;2.13,.48,;2.13,2.02,;2.13,3.56,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,;-4.98,1.48,;-6.12,.44,;-5.3,2.98,;-4.66,-.03,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576405 (4-(3,5-dimethyl-1H-pyrazol-4-yl)[1,3]thiazolo[4,5-...) Show SMILES Cc1n[nH]c(C)c1-c1nccc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	894	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576405 (4-(3,5-dimethyl-1H-pyrazol-4-yl)[1,3]thiazolo[4,5-...) Show SMILES Cc1n[nH]c(C)c1-c1nccc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	297	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576406 (WO2022112919, Example 11) Show SMILES COc1ccc(-c2c(C)n[nH]c2C)c2ncsc12 |(-6.12,.44,;-4.98,1.48,;-3.51,1,;-2.37,2.03,;-.91,1.55,;-.59,.05,;.88,-.43,;2.13,.48,;2.13,2.02,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;-1.73,-.98,;-1.73,-2.52,;-3.19,-3,;-4.1,-1.75,;-3.19,-.51,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576407 (4-(3,5-di ethyl-1H-pyrazol-4-yl)-7-fluoro-1,3-benz...) Show SMILES Cc1n[nH]c(C)c1-c1ccc(F)c2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-4.98,1.48,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576408 (4-(3,5-dimethyl- 1H-pyrazol-4-yl)-6-methyl-1,3-ben...) Show SMILES Cc1n[nH]c(C)c1-c1cc(C)cc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-2.69,3.54,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576408 (4-(3,5-dimethyl- 1H-pyrazol-4-yl)-6-methyl-1,3-ben...) Show SMILES Cc1n[nH]c(C)c1-c1cc(C)cc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-2.69,3.54,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576409 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-6-methoxy-1,3-ben...) Show SMILES COc1cc(-c2c(C)n[nH]c2C)c2ncsc2c1 |(-4.16,4.01,;-2.69,3.54,;-2.37,2.03,;-.91,1.55,;-.59,.05,;.88,-.43,;2.13,.48,;2.13,2.02,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;-1.73,-.98,;-1.73,-2.52,;-3.19,-3,;-4.1,-1.75,;-3.19,-.51,;-3.51,1,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576409 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-6-methoxy-1,3-ben...) Show SMILES COc1cc(-c2c(C)n[nH]c2C)c2ncsc2c1 |(-4.16,4.01,;-2.69,3.54,;-2.37,2.03,;-.91,1.55,;-.59,.05,;.88,-.43,;2.13,.48,;2.13,2.02,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;-1.73,-.98,;-1.73,-2.52,;-3.19,-3,;-4.1,-1.75,;-3.19,-.51,;-3.51,1,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576410 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-6-fluoro-1,3-benz...) Show SMILES Cc1n[nH]c(C)c1-c1cc(F)cc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-2.69,3.54,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576410 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-6-fluoro-1,3-benz...) Show SMILES Cc1n[nH]c(C)c1-c1cc(F)cc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-2.69,3.54,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576411 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-1,3-benzothiazole...) Show SMILES Cc1n[nH]c(C)c1-c1cc(cc2scnc12)C#N |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,;-2.69,3.54,;-3.01,5.04,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	159	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576412 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-5-fluoro-1,3-benz...) Show SMILES Cc1n[nH]c(C)c1-c1c(F)ccc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;.24,2.58,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576413 (4-[5- ethyl-3-(trifluoro ethyl)-1 H-pyrazol-4-yl]-...) Show SMILES Cc1[nH]nc(c1-c1cccc2scnc12)C(F)(F)F |(.45,-3.14,;1.36,-1.89,;2.9,-1.89,;3.37,-.43,;2.13,.48,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,;2.13,2.02,;.79,2.79,;3.46,2.79,;3.46,1.25,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	133	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576414 (7-(3,5-dimethyl-1 H-pyrazol-4-yl)[1,3]thiazolo[5,4...) Show SMILES Cc1n[nH]c(C)c1-c1ccnc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	n/a	165	n/a	n/a	n/a	n/a
TBA					Assay Description TTR SPA binding assays were performed in a final volume of 60 mI containing 100 ng human TTR (biotinylated recombinant protein) coupled to 25 pg SPA ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM576396 (4-(3,5-dimethyl-1H-pyrazol-4-yl)-1,3-benzothiazole...) Show SMILES Cc1n[nH]c(C)c1-c1cccc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022112919	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Affinity and Reversibility -The binding affinity and kinetics of binding were measured using Surface Plasmon Resonance based binding assay. These exp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RB77VN
					More data for this Ligand-Target Pair