Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50313079 (3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars | DrugBank Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189893 (CHEMBL3828679) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189893 (CHEMBL3828679) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50313079 (3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars | DrugBank Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189894 (CHEMBL3827011) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189894 (CHEMBL3827011) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189895 (CHEMBL3828028) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189895 (CHEMBL3828028) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189896 (CHEMBL3827624) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189892 (CHEMBL3827856) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189888 (CHEMBL3827449) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189891 (CHEMBL3828644) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189887 (CHEMBL3827347) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189889 (CHEMBL3828273) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189896 (CHEMBL3827624) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189892 (CHEMBL3827856) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189888 (CHEMBL3827449) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189890 (CHEMBL3828739) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189889 (CHEMBL3828273) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189887 (CHEMBL3827347) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189891 (CHEMBL3828644) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.03E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50189890 (CHEMBL3828739) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.19E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) Article DOI: 10.1016/j.bmcl.2016.06.070 BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50504686 (CHEMBL4441833) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 6.06E+7 | n/a | n/a | n/a | n/a | n/a |
Kazan Scientific Center of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Reactivation of POX-inhibited human recombinant AChE assessed as dissociation rate constant using ATC as substrate incubated for 60 mins followed by ... | Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111787 BindingDB Entry DOI: 10.7270/Q22J6G4M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50239371 (Atnaa | CHEBI:8354 | Duodote | Pralidoxime) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a |
Kazan Scientific Center of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Reactivation of POX-inhibited human recombinant AChE assessed as dissociation rate constant using ATC as substrate incubated for 60 mins followed by ... | Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111787 BindingDB Entry DOI: 10.7270/Q22J6G4M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50504685 (CHEMBL4541746) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 5.50E+6 | n/a | n/a | n/a | n/a | n/a |
Kazan Scientific Center of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Reactivation of POX-inhibited human recombinant AChE assessed as dissociation rate constant using ATC as substrate incubated for 60 mins followed by ... | Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111787 BindingDB Entry DOI: 10.7270/Q22J6G4M | |||||||||||
More data for this Ligand-Target Pair |