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Compile Data Set for Download or QSAR

Found 1826 hits with Last Name = 'pinard' and Initial = 'e'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin alpha-5


(Homo sapiens (Human))
BDBM10484
PNG
(US11091471, Example RO-301 | US8846719, 301)
Show SMILES Cc1onc(c1COc1ccc(cn1)C(=O)NC1CCOCC1)-c1ccc(Cl)cn1
Show InChI InChI=1S/C21H21ClN4O4/c1-13-17(20(26-30-13)18-4-3-15(22)11-23-18)12-29-19-5-2-14(10-24-19)21(27)25-16-6-8-28-9-7-16/h2-5,10-11,16H,6-9,12H2,1H3,(H,25,27)
PDB

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0.200n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Integrin alpha-5


(Homo sapiens (Human))
BDBM513334
PNG
(US11091471, Example RE-B)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1CCOCC1)-c1ccc(Cl)cn1
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0.400n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513240
PNG
(6-((5-methyl-3-(6-methylpyridazin-3-yl)isoxazol-4-...)
Show SMILES Cc1onc(c1COc1ccc(cn1)C(=O)NC1CCOCC1)-c1ccc(C)nn1
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0.400n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513241
PNG
(N-((1S)-1-(hydroxymethyl)butyl)-6-((5-methyl-3-(6-...)
Show SMILES CCC[C@@H](CO)NC(=O)c1ccc(OCc2c(C)onc2-c2ccc(C)nn2)nc1 |r|
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0.800n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Integrin alpha-5


(Homo sapiens (Human))
BDBM133559
PNG
(US11091471, Example RO-251 | US8846719, 251)
Show SMILES Cc1onc(c1COc1ccc(cn1)C(=O)NC1CCOCC1)-c1ccc(C)cc1
Show InChI InChI=1S/C23H25N3O4/c1-15-3-5-17(6-4-15)22-20(16(2)30-26-22)14-29-21-8-7-18(13-24-21)23(27)25-19-9-11-28-12-10-19/h3-8,13,19H,9-12,14H2,1-2H3,(H,25,27)
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1n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513325
PNG
(6-((5-methyl-3-(6-methylpyridazin-3-yl)isoxazol-4-...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1CCOCC1)-c1ccc(C)nn1
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1n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Integrin alpha-5


(Homo sapiens (Human))
BDBM133580
PNG
(US11091471, Example RO-272 | US8846719, 272)
Show SMILES Cc1onc(c1COc1ccc(cn1)C(=O)NC1CCOCC1)-c1ccccn1
Show InChI InChI=1S/C21H22N4O4/c1-14-17(20(25-29-14)18-4-2-3-9-22-18)13-28-19-6-5-15(12-23-19)21(26)24-16-7-10-27-11-8-16/h2-6,9,12,16H,7-8,10-11,13H2,1H3,(H,24,26)
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1n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513187
PNG
(5-methyl-6-((5-methyl-3-(6-methylpyridin-3-yl)isox...)
Show SMILES Cc1onc(c1COc1nnc(cc1C)C(N)=O)-c1ccc(C)nc1
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1.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513040
PNG
(N-ethyl-6-((5-methyl-3-(6-methyl-3-pyridyl)isoxazo...)
Show SMILES CCNC(=O)c1ccc(OCc2c(C)onc2-c2ccc(C)nc2)nc1
PDB

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1.40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513191
PNG
(5-methyl-6-((5-methyl-3-(6-methylpyridin-3-yl)isox...)
Show SMILES Cc1onc(c1COc1nnc(cc1C)C(=O)NC1CCOCC1)-c1ccc(C)nc1
PDB

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2.40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513297
PNG
(6-((5-cyclopropyl-3-(6-methylpyridazin-3-yl)isoxaz...)
Show SMILES Cc1ccc(nn1)-c1noc(C2CC2)c1COc1ccc(nn1)C(=O)NC1CCOCC1
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2.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Integrin alpha-5


(Homo sapiens (Human))
BDBM513332
PNG
(US11091471, Example RO-094)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1CCOCC1)-c1ccccn1
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2.90n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513324
PNG
(6-((5-(fluoromethyl)-3-(6-methylpyridazin-3-yl)iso...)
Show SMILES Cc1ccc(nn1)-c1noc(CF)c1COc1ccc(nn1)C(=O)NC1CCOCC1
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3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513146
PNG
(N-methyl-6-((5-methyl-3-(6-methylpyridin-3-yl)isox...)
Show SMILES CNC(=O)c1ccc(OCc2c(C)onc2-c2ccc(C)nc2)nn1
PDB

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3.5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513121
PNG
(6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-yl...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1COC1)-c1ccc(C)nc1
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4.40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513175
PNG
((6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-y...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N1CCC11COC1)-c1ccc(C)nc1
PDB

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4.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513243
PNG
(N-(4-methyl-1,1-dioxidotetrahydro-2H-thiopyran-4-y...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1(C)CCS(=O)(=O)CC1)-c1ccc(C)nc1
PDB

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4.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513274
PNG
(4-methoxy-6-((5-methyl-3-(6-methylpyridin-3-yl)iso...)
Show SMILES COc1cc(OCc2c(C)onc2-c2ccc(C)nc2)ncc1C(=O)NC1CCOCC1
PDB

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4.70n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513032
PNG
(6-((5-methyl-3-(6-methyl-3-pyridyl)isoxazol-4-yl)m...)
Show SMILES Cc1onc(c1COc1ccc(cn1)C(=O)NC1CCOCC1)-c1ccc(C)nc1
PDB

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4.80n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513248
PNG
(N-(1-isopropylazetidin-3-yl)-6-((5-methyl-3-(6-met...)
Show SMILES CC(C)N1CC(C1)NC(=O)c1ccc(OCc2c(C)onc2-c2ccc(C)nc2)nn1
PDB

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4.90n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513281
PNG
(N-((1R,3S)-3-hydroxy-3-(trifluoromethyl)cyclopenty...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N[C@@H]1CC[C@](O)(C1)C(F)(F)F)-c1ccc(C)nc1 |r|
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5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513210
PNG
(6-((5-methyl-3-(6-methylpyridin-3-yl) isoxazol-4-y...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1(C)COC1)-c1ccc(C)nc1
PDB

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5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513081
PNG
(N-((3S)-1,1-dioxothiolan-3-yl)-6-((5-methyl-3-(6-m...)
Show SMILES Cc1onc(c1COc1ccc(cn1)C(=O)N[C@H]1CCS(=O)(=O)C1)-c1ccc(C)nc1 |r|
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5.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513201
PNG
(5-((5-methyl-3-(6-methyl-3-pyridyl)isoxazol-4-yl)m...)
Show SMILES Cc1onc(c1COc1cnc(cn1)C(=O)NC1COC1)-c1ccc(C)nc1
PDB

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5.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513103
PNG
(N-cyclopropyl-6-((5-methyl-3-(6-methylpyridin-3-yl...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1CC1)-c1ccc(C)nc1
PDB

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5.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513284
PNG
(N-((1RS,3RS)-3-hydroxycyclopentyl)-6-((5-methyl-3-...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N[C@@H]1CC[C@@H](O)C1)-c1ccc(C)nc1 |r|
PDB

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5.30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513088
PNG
(N-(1,1-dioxothian-4-yl)-6-((5-methyl-3-(6-methylpy...)
Show SMILES Cc1onc(c1COc1ccc(cn1)C(=O)NC1CCS(=O)(=O)CC1)-c1ccc(C)nc1
PDB

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5.40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513285
PNG
(US11091471, Example 153 | trans-N-(4-hydroxycycloh...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(C)nc1 |r,wU:20.22,wD:17.18,(1.45,5.35,;-.04,4.95,;-1.29,5.85,;-2.53,4.95,;-2.06,3.48,;-.52,3.48,;.25,2.15,;1.79,2.15,;2.56,.82,;4.1,.82,;4.87,-.52,;4.1,-1.85,;2.56,-1.85,;1.79,-.52,;4.87,-3.19,;6.41,-3.19,;4.1,-4.52,;2.56,-4.52,;1.79,-3.19,;.25,-3.19,;-.52,-4.52,;-2.06,-4.52,;.25,-5.85,;1.79,-5.85,;-3.15,2.39,;-4.63,2.79,;-5.72,1.7,;-5.32,.22,;-6.41,-.87,;-3.84,-.18,;-2.75,.91,)|
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TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513223
PNG
(2-(1,1-dioxothian-4-yl)-6-((5-methyl-3-(6-methylpy...)
Show SMILES Cc1onc(c1COc1cc2CN(C3CCS(=O)(=O)CC3)C(=O)c2cn1)-c1ccc(C)nc1
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5.5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513123
PNG
((RS)—N-(1,1-dioxothiolan-3-yl)-6-((5-methyl-3-(6-m...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1CCS(=O)(=O)C1)-c1ccc(C)nc1
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5.80n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513179
PNG
((3-hydroxyazetidin-1-yl)(6-((5-methyl-3-(6-methylp...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N1CC(O)C1)-c1ccc(C)nc1
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5.80n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513289
PNG
(3-oxa-6-azabicyclo[3.1.1]heptan-6-yl(6-((5-methyl-...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N1C2CC1COC2)-c1ccc(C)nc1
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6n/an/an/an/an/an/an/an/a


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Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513260
PNG
(6-((3-(6-cyclopropyl-3-pyridyl)-5-methyl-isoxazol-...)
Show SMILES Cc1onc(c1COc1ccc(cn1)C(=O)NC1CCOCC1)-c1ccc(nc1)C1CC1
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6.10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513225
PNG
(2-((5-methyl-3-(6-methyl-3-pyridyl)isoxazol-4-yl)m...)
Show SMILES Cc1onc(c1COc1ccc2C(=O)N(Cc2n1)C1CCOCC1)-c1ccc(C)nc1
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6.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513216
PNG
(N-(1-(hydroxymethyl)cyclopropyl)-6-((5-methyl-3-(6...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1(CO)CC1)-c1ccc(C)nc1
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6.30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513244
PNG
((2,2-dioxido-2-thia-6-azaspiro[3.3]heptan-6-yl)(6-...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N1CC2(C1)CS(=O)(=O)C2)-c1ccc(C)nc1
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Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513144
PNG
((RS)-6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1CCOC1)-c1ccc(C)nc1
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6.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513231
PNG
((R)-6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N[C@@H]1CCCOC1)-c1ccc(C)nc1 |r|
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6.80n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513170
PNG
((6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-y...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N1CC2(COC2)C1)-c1ccc(C)nc1
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7.10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513161
PNG
(US11091471, Example 57 | azetidin-1-yl(6-((5-methy...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N1CCC1)-c1ccc(C)nc1
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7.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513178
PNG
((3-fluoroazetidin-1-yl)(6-((5-methyl-3-(6-methylpy...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N1CC(F)C1)-c1ccc(C)nc1
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TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513228
PNG
(2-(4,4-difluorocyclohexyl)-6-((5-methyl-3-(6-methy...)
Show SMILES Cc1onc(c1COc1cc2CN(C3CCC(F)(F)CC3)C(=O)c2cn1)-c1ccc(C)nc1
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TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513042
PNG
((S)—N-(1-hydroxypentan-2-yl)-6-((5-methyl-3-(6-met...)
Show SMILES CCC[C@@H](CO)NC(=O)c1ccc(OCc2c(C)onc2-c2ccc(C)nc2)nc1 |r|
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7.30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513128
PNG
(N-isopropyl-6-((5-methyl-3-(6-methylpyridin-3-yl)i...)
Show SMILES CC(C)NC(=O)c1ccc(OCc2c(C)onc2-c2ccc(C)nc2)nn1
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TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513298
PNG
(US11091471, Example 166 | trans-N-((1RS,3RS)-3-met...)
Show SMILES CO[C@@H]1CC[C@H](C1)NC(=O)c1ccc(OCc2c(C)onc2-c2ccc(C)nc2)nn1 |r|
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7.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513151
PNG
(6-((5-methyl-3-(6-methyl-3-pyridyl)isoxazol-4-yl)m...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NCC1COC1)-c1ccc(C)nc1
PDB

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7.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513127
PNG
(N-ethyl-6-((5-methyl-3-(6-methylpyridin-3-yl)isoxa...)
Show SMILES CCNC(=O)c1ccc(OCc2c(C)onc2-c2ccc(C)nc2)nn1
PDB

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7.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513183
PNG
(N-(1-cyanocyclopropyl)-6-((5-methyl-3-(6-methylpyr...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1(CC1)C#N)-c1ccc(C)nc1
PDB

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7.70n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513288
PNG
(N-(3-hydroxycyclohexyl)-6-((5-methyl-3-(6-methylpy...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1CCCC(O)C1)-c1ccc(C)nc1
PDB

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7.80n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1


(Homo sapiens (Human))
BDBM513159
PNG
((3-hydroxy-3-methylazetidin-1-yl)(6-((5-methyl-3-(...)
Show SMILES Cc1onc(c1COc1ccc(nn1)C(=O)N1CC(C)(O)C1)-c1ccc(C)nc1
PDB

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7.90n/an/an/an/an/an/an/an/a


TBA

Assay Description
Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2W66PWZ
More data for this
Ligand-Target Pair
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