Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31270 (CHEMBL360141 | isoindolinone scaffold, 65) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31251 (CHEMBL178106 | isoindolinone scaffold, 40) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.79E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31230 (CHEMBL179549 | isoindolinone scaffold, 16) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31241 (isoindolinone scaffold, 30) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31268 (isoindolinone scaffold, 63) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31231 (CHEMBL360920 | isoindolinone scaffold, 17) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31266 (isoindolinone scaffold, 61) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31232 (CHEMBL179114 | isoindolinone scaffold, 18) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31262 (isoindolinone scaffold, 57) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31264 (isoindolinone scaffold, 59) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31265 (isoindolinone scaffold, 60) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31267 (isoindolinone scaffold, 62) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31236 (isoindolinone scaffold, 22) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31237 (isoindolinone scaffold, 24) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.90E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31229 (isoindolinone scaffold, 15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.50E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31258 (isoindolinone scaffold, 49) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31228 (CHEMBL182052 | isoindolinone scaffold, 14) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31227 (CHEMBL181688 | isoindolinone scaffold, 13) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.20E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31246 (isoindolinone scaffold, 35) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.60E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31245 (isoindolinone scaffold, 34) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 9.70E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31271 (isoindolinone scaffold, 67) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.03E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31269 (isoindolinone scaffold, 64) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.03E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31247 (isoindolinone scaffold, 36) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.16E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31256 (isoindolinone scaffold, 47) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.81E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31249 (isoindolinone scaffold, 38) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.91E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31242 (isoindolinone scaffold, 31) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.06E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31244 (isoindolinone scaffold, 33) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.14E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31243 (isoindolinone scaffold, 32) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.21E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31250 (isoindolinone scaffold, 39) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.32E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31248 (isoindolinone scaffold, 37) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.43E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31259 (isoindolinone scaffold, 50) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.75E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31239 (isoindolinone scaffold, 26) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.81E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31233 (isoindolinone scaffold, 19) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.84E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31263 (isoindolinone scaffold, 58) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31238 (isoindolinone scaffold, 25) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.11E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31240 (isoindolinone scaffold, 28) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.15E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31253 (isoindolinone scaffold, 43) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.26E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31252 (isoindolinone scaffold, 41) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.45E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31260 (isoindolinone scaffold, 51) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31234 (isoindolinone scaffold, 20) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.93E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31257 (isoindolinone scaffold, 48) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.13E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31235 (isoindolinone scaffold, 21) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.39E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31254 (isoindolinone scaffold, 44) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31255 (isoindolinone scaffold, 45) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31261 (isoindolinone scaffold, 53) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle upon Tyne | Assay Description For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen... | J Med Chem 49: 6209-21 (2006) Article DOI: 10.1021/jm0601194 BindingDB Entry DOI: 10.7270/Q2R49P3V | |||||||||||
More data for this Ligand-Target Pair |