Found 311 hits with Last Name = 'rummey' and Initial = 'c' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296131
(CHEMBL564249 | N-(((S)-1-((R)-3-amino-4-(3-chlorop...)Show SMILES CS(=O)(=O)c1cccc(c1)C(=O)NC[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H28ClN3O4S/c1-32(30,31)21-9-3-6-17(13-21)23(29)26-15-20-8-4-10-27(20)22(28)14-19(25)12-16-5-2-7-18(24)11-16/h2-3,5-7,9,11,13,19-20H,4,8,10,12,14-15,25H2,1H3,(H,26,29)/t19-,20+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
| MMDB PDB Article PubMed
| n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 4201-3 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.109 BindingDB Entry DOI: 10.7270/Q24749XM |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302961
((R)-3-amino-1-((S)-2-(3-(1-(methylsulfonyl)azetidi...)Show SMILES CS(=O)(=O)N1CC(C1)c1noc(n1)[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H24F3N5O4S/c1-33(30,31)27-9-12(10-27)19-25-20(32-26-19)17-3-2-4-28(17)18(29)7-13(24)5-11-6-15(22)16(23)8-14(11)21/h6,8,12-13,17H,2-5,7,9-10,24H2,1H3/t13-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296761
(CHEMBL564105 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES CN(C[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F)C(=O)C1CC1 |r| Show InChI InChI=1S/C20H26F3N3O2/c1-25(20(28)12-4-5-12)11-15-3-2-6-26(15)19(27)9-14(24)7-13-8-17(22)18(23)10-16(13)21/h8,10,12,14-15H,2-7,9,11,24H2,1H3/t14-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296768
(CHEMBL554908 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)C1CC1(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H22F5N3O2/c20-14-7-16(22)15(21)5-10(14)4-11(25)6-17(28)27-3-1-2-12(27)9-26-18(29)13-8-19(13,23)24/h5,7,11-13H,1-4,6,8-9,25H2,(H,26,29)/t11-,12+,13?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296755
(CHEMBL558452 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES CN(C[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F)S(=O)(=O)C(F)(F)F |r| Show InChI InChI=1S/C17H21F6N3O3S/c1-25(30(28,29)17(21,22)23)9-12-3-2-4-26(12)16(27)7-11(24)5-10-6-14(19)15(20)8-13(10)18/h6,8,11-12H,2-5,7,9,24H2,1H3/t11-,12+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302958
((R)-3-amino-1-((S)-2-(3-(1-(trifluoromethyl)cyclop...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1nc(no1)C1(CC1)C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H20F6N4O2/c21-12-9-14(23)13(22)7-10(12)6-11(27)8-16(31)30-5-1-2-15(30)17-28-18(29-32-17)19(3-4-19)20(24,25)26/h7,9,11,15H,1-6,8,27H2/t11-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302972
((R)-3-amino-1-((S)-2-(5-(3-methyloxetan-3-yl)-1,2,...)Show SMILES CC1(COC1)c1nc(no1)[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H23F3N4O3/c1-20(9-29-10-20)19-25-18(26-30-19)16-3-2-4-27(16)17(28)7-12(24)5-11-6-14(22)15(23)8-13(11)21/h6,8,12,16H,2-5,7,9-10,24H2,1H3/t12-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302956
((R)-3-amino-1-((S)-2-(3-tert-butyl-1,2,4-oxadiazol...)Show SMILES CC(C)(C)c1noc(n1)[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H25F3N4O2/c1-20(2,3)19-25-18(29-26-19)16-5-4-6-27(16)17(28)9-12(24)7-11-8-14(22)15(23)10-13(11)21/h8,10,12,16H,4-7,9,24H2,1-3H3/t12-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302964
((R)-3-amino-1-((S)-2-(3-(pyrazin-2-yl)-1,2,4-oxadi...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1nc(no1)-c1cnccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H19F3N6O2/c21-13-9-15(23)14(22)7-11(13)6-12(24)8-18(30)29-5-1-2-17(29)20-27-19(28-31-20)16-10-25-3-4-26-16/h3-4,7,9-10,12,17H,1-2,5-6,8,24H2/t12-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296773
(6-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1COc1ccc(cn1)C#N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H21F3N4O2/c22-17-9-19(24)18(23)7-14(17)6-15(26)8-21(29)28-5-1-2-16(28)12-30-20-4-3-13(10-25)11-27-20/h3-4,7,9,11,15-16H,1-2,5-6,8,12,26H2/t15-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296767
(CHEMBL563901 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)C1CCC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H26F3N3O2/c21-16-10-18(23)17(22)8-13(16)7-14(24)9-19(27)26-6-2-5-15(26)11-25-20(28)12-3-1-4-12/h8,10,12,14-15H,1-7,9,11,24H2,(H,25,28)/t14-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296772
(2-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1COc1cc(ccn1)C#N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H21F3N4O2/c22-17-10-19(24)18(23)8-14(17)7-15(26)9-21(29)28-5-1-2-16(28)12-30-20-6-13(11-25)3-4-27-20/h3-4,6,8,10,15-16H,1-2,5,7,9,12,26H2/t15-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296769
(CHEMBL552069 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)C1(CC1)C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H23F6N3O2/c21-14-9-16(23)15(22)7-11(14)6-12(27)8-17(30)29-5-1-2-13(29)10-28-18(31)19(3-4-19)20(24,25)26/h7,9,12-13H,1-6,8,10,27H2,(H,28,31)/t12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296754
(CHEMBL558647 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CN(C1CC1)S(=O)(=O)C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H23F6N3O3S/c20-15-9-17(22)16(21)7-11(15)6-12(26)8-18(29)27-5-1-2-14(27)10-28(13-3-4-13)32(30,31)19(23,24)25/h7,9,12-14H,1-6,8,10,26H2/t12-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302957
((R)-3-amino-1-((S)-2-(3-(cyclopropylmethyl)-1,2,4-...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1nc(CC2CC2)no1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H23F3N4O2/c21-14-10-16(23)15(22)8-12(14)7-13(24)9-19(28)27-5-1-2-17(27)20-25-18(26-29-20)6-11-3-4-11/h8,10-11,13,17H,1-7,9,24H2/t13-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302966
((R)-3-amino-1-((S)-2-(3-(3,5-difluoropyridin-2-yl)...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1nc(no1)-c1ncc(F)cc1F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H18F5N5O2/c22-11-6-16(26)19(28-9-11)20-29-21(33-30-20)17-2-1-3-31(17)18(32)7-12(27)4-10-5-14(24)15(25)8-13(10)23/h5-6,8-9,12,17H,1-4,7,27H2/t12-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296779
(2-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNc1ncccc1C#N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H22F3N5O/c22-17-10-19(24)18(23)8-14(17)7-15(26)9-20(30)29-6-2-4-16(29)12-28-21-13(11-25)3-1-5-27-21/h1,3,5,8,10,15-16H,2,4,6-7,9,12,26H2,(H,27,28)/t15-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296762
(CHEMBL550114 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)CC(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C18H21F6N3O2/c19-13-7-15(21)14(20)5-10(13)4-11(25)6-17(29)27-3-1-2-12(27)9-26-16(28)8-18(22,23)24/h5,7,11-12H,1-4,6,8-9,25H2,(H,26,28)/t11-,12+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296781
(6-(((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)bu...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNc1ccc(cn1)C#N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H22F3N5O/c22-17-9-19(24)18(23)7-14(17)6-15(26)8-21(30)29-5-1-2-16(29)12-28-20-4-3-13(10-25)11-27-20/h3-4,7,9,11,15-16H,1-2,5-6,8,12,26H2,(H,27,28)/t15-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296765
(CHEMBL558322 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES CC(C)(C)C(=O)NC[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H28F3N3O2/c1-20(2,3)19(28)25-11-14-5-4-6-26(14)18(27)9-13(24)7-12-8-16(22)17(23)10-15(12)21/h8,10,13-14H,4-7,9,11,24H2,1-3H3,(H,25,28)/t13-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296774
((R)-3-amino-1-((S)-2-((4-(trifluoromethyl)pyrimidi...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNc1nccc(n1)C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H21F6N5O/c21-14-9-16(23)15(22)7-11(14)6-12(27)8-18(32)31-5-1-2-13(31)10-29-19-28-4-3-17(30-19)20(24,25)26/h3-4,7,9,12-13H,1-2,5-6,8,10,27H2,(H,28,29,30)/t12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302959
((R)-3-amino-1-((S)-2-(3-morpholino-1,2,4-oxadiazol...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1nc(no1)N1CCOCC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H24F3N5O3/c21-14-11-16(23)15(22)9-12(14)8-13(24)10-18(29)28-3-1-2-17(28)19-25-20(26-31-19)27-4-6-30-7-5-27/h9,11,13,17H,1-8,10,24H2/t13-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302960
((R)-3-amino-1-((S)-2-(3-(pyrrolidin-1-yl)-1,2,4-ox...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1nc(no1)N1CCCC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H24F3N5O2/c21-14-11-16(23)15(22)9-12(14)8-13(24)10-18(29)28-7-3-4-17(28)19-25-20(26-30-19)27-5-1-2-6-27/h9,11,13,17H,1-8,10,24H2/t13-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302965
((R)-3-amino-1-((S)-2-(3-(pyrimidin-2-yl)-1,2,4-oxa...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1nc(no1)-c1ncccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H19F3N6O2/c21-13-10-15(23)14(22)8-11(13)7-12(24)9-17(30)29-6-1-3-16(29)20-27-19(28-31-20)18-25-4-2-5-26-18/h2,4-5,8,10,12,16H,1,3,6-7,9,24H2/t12-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296780
(6-((((S)-1-((R)-3-amino-4-(2,4,5-trifluorophenyl)b...)Show SMILES CN(C[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F)c1ccc(cn1)C#N |r| Show InChI InChI=1S/C22H24F3N5O/c1-29(21-5-4-14(11-26)12-28-21)13-17-3-2-6-30(17)22(31)9-16(27)7-15-8-19(24)20(25)10-18(15)23/h4-5,8,10,12,16-17H,2-3,6-7,9,13,27H2,1H3/t16-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296766
(CHEMBL557723 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)C1CCCC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H28F3N3O2/c22-17-11-19(24)18(23)9-14(17)8-15(25)10-20(28)27-7-3-6-16(27)12-26-21(29)13-4-1-2-5-13/h9,11,13,15-16H,1-8,10,12,25H2,(H,26,29)/t15-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302962
((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...)Show SMILES CC(=O)N1CC(C1)c1noc(n1)[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H24F3N5O3/c1-11(30)28-9-13(10-28)20-26-21(32-27-20)18-3-2-4-29(18)19(31)7-14(25)5-12-6-16(23)17(24)8-15(12)22/h6,8,13-14,18H,2-5,7,9-10,25H2,1H3/t14-,18+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296776
((R)-3-amino-1-((S)-2-((pyrimidin-2-ylamino)methyl)...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNc1ncccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H22F3N5O/c20-15-10-17(22)16(21)8-12(15)7-13(23)9-18(28)27-6-1-3-14(27)11-26-19-24-4-2-5-25-19/h2,4-5,8,10,13-14H,1,3,6-7,9,11,23H2,(H,24,25,26)/t13-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296756
(CHEMBL559602 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNS(=O)(=O)CC(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H21F6N3O3S/c18-13-7-15(20)14(19)5-10(13)4-11(24)6-16(27)26-3-1-2-12(26)8-25-30(28,29)9-17(21,22)23/h5,7,11-12,25H,1-4,6,8-9,24H2/t11-,12+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296763
(CHEMBL557860 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES CC(F)(F)C(=O)NC[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C18H22F5N3O2/c1-18(22,23)17(28)25-9-12-3-2-4-26(12)16(27)7-11(24)5-10-6-14(20)15(21)8-13(10)19/h6,8,11-12H,2-5,7,9,24H2,1H3,(H,25,28)/t11-,12+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296771
((R)-3-amino-1-((S)-2-((2-(trifluoromethyl)pyrimidi...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1COc1ccnc(n1)C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H20F6N4O2/c21-14-9-16(23)15(22)7-11(14)6-12(27)8-18(31)30-5-1-2-13(30)10-32-17-3-4-28-19(29-17)20(24,25)26/h3-4,7,9,12-13H,1-2,5-6,8,10,27H2/t12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296764
(CHEMBL558323 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES CC(C)(F)C(=O)NC[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H25F4N3O2/c1-19(2,23)18(28)25-10-13-4-3-5-26(13)17(27)8-12(24)6-11-7-15(21)16(22)9-14(11)20/h7,9,12-13H,3-6,8,10,24H2,1-2H3,(H,25,28)/t12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296778
((R)-3-amino-1-((S)-2-((5-fluoropyridin-2-ylamino)m...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNc1ccc(F)cn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H22F4N4O/c21-13-3-4-19(26-10-13)27-11-15-2-1-5-28(15)20(29)8-14(25)6-12-7-17(23)18(24)9-16(12)22/h3-4,7,9-10,14-15H,1-2,5-6,8,11,25H2,(H,26,27)/t14-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296760
(CHEMBL550321 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES CN(C[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F)C(=O)C(C)(C)C |r| Show InChI InChI=1S/C21H30F3N3O2/c1-21(2,3)20(29)26(4)12-15-6-5-7-27(15)19(28)10-14(25)8-13-9-17(23)18(24)11-16(13)22/h9,11,14-15H,5-8,10,12,25H2,1-4H3/t14-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302955
((R)-3-amino-1-((S)-2-(3-cyclopropyl-1,2,4-oxadiazo...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1nc(no1)C1CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H21F3N4O2/c20-13-9-15(22)14(21)7-11(13)6-12(23)8-17(27)26-5-1-2-16(26)19-24-18(25-28-19)10-3-4-10/h7,9-10,12,16H,1-6,8,23H2/t12-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296775
((R)-3-amino-1-((S)-2-((5-fluoropyrimidin-2-ylamino...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNc1ncc(F)cn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H21F4N5O/c20-12-8-25-19(26-9-12)27-10-14-2-1-3-28(14)18(29)6-13(24)4-11-5-16(22)17(23)7-15(11)21/h5,7-9,13-14H,1-4,6,10,24H2,(H,25,26,27)/t13-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296759
(CHEMBL559601 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES CN(C[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F)C(=O)C(C)(F)F |r| Show InChI InChI=1S/C19H24F5N3O2/c1-19(23,24)18(29)26(2)10-13-4-3-5-27(13)17(28)8-12(25)6-11-7-15(21)16(22)9-14(11)20/h7,9,12-13H,3-6,8,10,25H2,1-2H3/t12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296135
(CHEMBL561322 | N-(((S)-1-((R)-3-amino-4-(3-chlorop...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNS(=O)(=O)c1ccccc1)Cc1cccc(Cl)c1 |r| Show InChI InChI=1S/C21H26ClN3O3S/c22-17-7-4-6-16(12-17)13-18(23)14-21(26)25-11-5-8-19(25)15-24-29(27,28)20-9-2-1-3-10-20/h1-4,6-7,9-10,12,18-19,24H,5,8,11,13-15,23H2/t18-,19+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 4201-3 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.109 BindingDB Entry DOI: 10.7270/Q24749XM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296120
(CHEMBL563272 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNS(=O)(=O)C1CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C18H24F3N3O3S/c19-15-9-17(21)16(20)7-11(15)6-12(22)8-18(25)24-5-1-2-13(24)10-23-28(26,27)14-3-4-14/h7,9,12-14,23H,1-6,8,10,22H2/t12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 4201-3 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.109 BindingDB Entry DOI: 10.7270/Q24749XM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296120
(CHEMBL563272 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNS(=O)(=O)C1CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C18H24F3N3O3S/c19-15-9-17(21)16(20)7-11(15)6-12(22)8-18(25)24-5-1-2-13(24)10-23-28(26,27)14-3-4-14/h7,9,12-14,23H,1-6,8,10,22H2/t12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296133
(CHEMBL563648 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)C1CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H24F3N3O2/c20-15-9-17(22)16(21)7-12(15)6-13(23)8-18(26)25-5-1-2-14(25)10-24-19(27)11-3-4-11/h7,9,11,13-14H,1-6,8,10,23H2,(H,24,27)/t13-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296133
(CHEMBL563648 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)C1CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H24F3N3O2/c20-15-9-17(22)16(21)7-12(15)6-13(23)8-18(26)25-5-1-2-14(25)10-24-19(27)11-3-4-11/h7,9,11,13-14H,1-6,8,10,23H2,(H,24,27)/t13-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 4201-3 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.109 BindingDB Entry DOI: 10.7270/Q24749XM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302963
((R)-3-amino-1-((S)-2-(3-(pyridin-2-yl)-1,2,4-oxadi...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1nc(no1)-c1ccccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H20F3N5O2/c22-14-11-16(24)15(23)9-12(14)8-13(25)10-19(30)29-7-3-5-18(29)21-27-20(28-31-21)17-4-1-2-6-26-17/h1-2,4,6,9,11,13,18H,3,5,7-8,10,25H2/t13-,18+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296770
((R)-3-amino-1-((S)-2-((cyclopropylmethoxy)methyl)p...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1COCC1CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H25F3N2O2/c20-16-9-18(22)17(21)7-13(16)6-14(23)8-19(25)24-5-1-2-15(24)11-26-10-12-3-4-12/h7,9,12,14-15H,1-6,8,10-11,23H2/t14-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302968
((R)-3-amino-1-((S)-2-(5-(1-(trifluoromethyl)cyclop...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1noc(n1)C1(CC1)C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H20F6N4O2/c21-12-9-14(23)13(22)7-10(12)6-11(27)8-16(31)30-5-1-2-15(30)17-28-18(32-29-17)19(3-4-19)20(24,25)26/h7,9,11,15H,1-6,8,27H2/t11-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296132
(CHEMBL561120 | N-(((S)-1-((R)-3-amino-4-(3-chlorop...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)C1CC1)Cc1cccc(Cl)c1 |r| Show InChI InChI=1S/C19H26ClN3O2/c20-15-4-1-3-13(9-15)10-16(21)11-18(24)23-8-2-5-17(23)12-22-19(25)14-6-7-14/h1,3-4,9,14,16-17H,2,5-8,10-12,21H2,(H,22,25)/t16-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 4201-3 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.109 BindingDB Entry DOI: 10.7270/Q24749XM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296757
(CHEMBL564283 | N-(((S)-1-((R)-3-amino-4-(2,4,5-tri...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNS(=O)(=O)C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H19F6N3O3S/c17-12-7-14(19)13(18)5-9(12)4-10(23)6-15(26)25-3-1-2-11(25)8-24-29(27,28)16(20,21)22/h5,7,10-11,24H,1-4,6,8,23H2/t10-,11+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296130
(CHEMBL564043 | N-(((S)-1-((R)-3-amino-4-(3-chlorop...)Show SMILES CS(=O)(=O)c1ccccc1C(=O)NC[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H28ClN3O4S/c1-32(30,31)21-10-3-2-9-20(21)23(29)26-15-19-8-5-11-27(19)22(28)14-18(25)13-16-6-4-7-17(24)12-16/h2-4,6-7,9-10,12,18-19H,5,8,11,13-15,25H2,1H3,(H,26,29)/t18-,19+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 4201-3 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.109 BindingDB Entry DOI: 10.7270/Q24749XM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50296777
((R)-3-amino-1-((S)-2-((6-(trifluoromethyl)pyridin-...)Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1CNc1ccc(nc1)C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H22F6N4O/c22-16-9-18(24)17(23)7-12(16)6-13(28)8-20(32)31-5-1-2-15(31)11-29-14-3-4-19(30-10-14)21(25,26)27/h3-4,7,9-10,13,15,29H,1-2,5-6,8,11,28H2/t13-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 19: 4818-23 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.036 BindingDB Entry DOI: 10.7270/Q20865B6 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50302971
((R)-3-amino-1-((S)-2-(5-(2-fluoropropan-2-yl)-1,2,...)Show SMILES CC(C)(F)c1nc(no1)[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H22F4N4O2/c1-19(2,23)18-25-17(26-29-18)15-4-3-5-27(15)16(28)8-11(24)6-10-7-13(21)14(22)9-12(10)20/h7,9,11,15H,3-6,8,24H2,1-2H3/t11-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Santhera Pharmaceuticals (Switzerland) Ltd
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay |
Bioorg Med Chem Lett 19: 6340-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2 |
More data for this Ligand-Target Pair | |