Found 19 hits with Last Name = 'sambre' and Initial = 'j' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414266
(CHEMBL569596)Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCc1ccc(OC)cc1 Show InChI InChI=1S/C27H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27(29)28-24-23-25-19-21-26(30-2)22-20-25/h7-8,10-11,19-22H,3-6,9,12-18,23-24H2,1-2H3,(H,28,29)/b8-7-,11-10- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50175105
((5Z,8Z,11Z,14Z)-N-(4-methoxyphenethyl)icosa-5,8,11...)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccc(OC)cc1 Show InChI InChI=1S/C29H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-29(31)30-26-25-27-21-23-28(32-2)24-22-27/h7-8,10-11,13-14,16-17,21-24H,3-6,9,12,15,18-20,25-26H2,1-2H3,(H,30,31)/b8-7-,11-10-,14-13-,17-16- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414268
(CHEMBL550631)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1cccc(OC)c1 Show InChI InChI=1S/C29H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23-29(31)30-25-24-27-21-20-22-28(26-27)32-2/h7-8,10-11,13-14,16-17,20-22,26H,3-6,9,12,15,18-19,23-25H2,1-2H3,(H,30,31)/b8-7-,11-10-,14-13-,17-16- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414267
(CHEMBL550549)Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCc1cccc(OC)c1 Show InChI InChI=1S/C27H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-27(29)28-23-22-25-19-18-20-26(24-25)30-2/h7-8,10-11,18-20,24H,3-6,9,12-17,21-23H2,1-2H3,(H,28,29)/b8-7-,11-10- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50056471
((9Z,12Z)-Octadeca-9,12-dienoic acid (2-hydroxy-eth...)Show InChI InChI=1S/C20H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h6-7,9-10,22H,2-5,8,11-19H2,1H3,(H,21,23)/b7-6-,10-9- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM22988
((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)Show InChI InChI=1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414261
(CHEMBL550431)Show InChI InChI=1S/C25H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-25(28)27-22-23-18-20-24(26)21-19-23/h6-7,9-10,18-21H,2-5,8,11-17,22H2,1H3,(H,27,28)/b7-6-,10-9- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414271
(CHEMBL561235)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCc1cccc(I)c1 Show InChI InChI=1S/C27H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-27(30)29-24-25-20-19-21-26(28)23-25/h6-7,9-10,12-13,15-16,19-21,23H,2-5,8,11,14,17-18,22,24H2,1H3,(H,29,30)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414263
(CHEMBL560697)Show InChI InChI=1S/C25H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-25(28)27-22-23-18-17-19-24(26)21-23/h6-7,9-10,17-19,21H,2-5,8,11-16,20,22H2,1H3,(H,27,28)/b7-6-,10-9- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414270
(CHEMBL550833)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccccc1OC Show InChI InChI=1S/C29H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29(31)30-26-25-27-22-20-21-23-28(27)32-2/h7-8,10-11,13-14,16-17,20-23H,3-6,9,12,15,18-19,24-26H2,1-2H3,(H,30,31)/b8-7-,11-10-,14-13-,17-16- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414269
(CHEMBL550831)Show InChI InChI=1S/C27H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22-27(29)28-24-23-25-20-18-19-21-26(25)30-2/h7-8,10-11,18-21H,3-6,9,12-17,22-24H2,1-2H3,(H,28,29)/b8-7-,11-10- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414262
(CHEMBL560500)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCc1ccc(I)cc1 Show InChI InChI=1S/C27H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-27(30)29-24-25-20-22-26(28)23-21-25/h6-7,9-10,12-13,15-16,20-23H,2-5,8,11,14,17-19,24H2,1H3,(H,29,30)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414264
(CHEMBL561236)Show InChI InChI=1S/C25H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21-25(28)27-22-23-19-17-18-20-24(23)26/h6-7,9-10,17-20H,2-5,8,11-16,21-22H2,1H3,(H,27,28)/b7-6-,10-9- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414260
(CHEMBL560499)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccccc1I Show InChI InChI=1S/C28H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23-28(31)30-25-24-26-21-19-20-22-27(26)29/h6-7,9-10,12-13,15-16,19-22H,2-5,8,11,14,17-18,23-25H2,1H3,(H,30,31)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.51E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414258
(CHEMBL564039)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1cccc(I)c1 Show InChI InChI=1S/C28H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-28(31)30-24-23-26-20-19-21-27(29)25-26/h6-7,9-10,12-13,15-16,19-21,25H,2-5,8,11,14,17-18,22-24H2,1H3,(H,30,31)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.89E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414257
(CHEMBL550428)Show InChI InChI=1S/C26H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-26(29)28-22-21-24-18-17-19-25(27)23-24/h6-7,9-10,17-19,23H,2-5,8,11-16,20-22H2,1H3,(H,28,29)/b7-6-,10-9- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414256
(CHEMBL550149)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccc(I)cc1 Show InChI InChI=1S/C28H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(31)30-25-24-26-20-22-27(29)23-21-26/h6-7,9-10,12-13,15-16,20-23H,2-5,8,11,14,17-19,24-25H2,1H3,(H,30,31)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.07E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414259
(CHEMBL561628)Show InChI InChI=1S/C26H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21-26(29)28-23-22-24-19-17-18-20-25(24)27/h6-7,9-10,17-20H,2-5,8,11-16,21-23H2,1H3,(H,28,29)/b7-6-,10-9- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.95E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50414265
(CHEMBL565224)Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCc1ccccc1I Show InChI InChI=1S/C27H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23-27(30)29-24-25-21-19-20-22-26(25)28/h6-7,9-10,12-13,15-16,19-22H,2-5,8,11,14,17-18,23-24H2,1H3,(H,29,30)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.46E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA |
J Med Chem 52: 4613-22 (2009)
Article DOI: 10.1021/jm900324e BindingDB Entry DOI: 10.7270/Q25X2B5M |
More data for this Ligand-Target Pair | |