Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (Homo sapiens (Human)) | BDBM18656 ((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a... | J Med Chem 49: 716-26 (2006) Article DOI: 10.1021/jm050293c BindingDB Entry DOI: 10.7270/Q2P84952 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18656 ((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a... | J Med Chem 49: 716-26 (2006) Article DOI: 10.1021/jm050293c BindingDB Entry DOI: 10.7270/Q2P84952 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149937 (US8975415, 219 | US9242973, 219) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 10.2 | n/a | 44.4 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149937 (US8975415, 219 | US9242973, 219) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 10.2 | -45.6 | 44.4 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149936 (US8975415, 218 | US9242973, 218) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 10.3 | -45.6 | 44.7 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149936 (US8975415, 218 | US9242973, 218) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 10.3 | n/a | 44.7 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18525 (Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a... | J Med Chem 49: 716-26 (2006) Article DOI: 10.1021/jm050293c BindingDB Entry DOI: 10.7270/Q2P84952 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM18525 (Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a... | J Med Chem 49: 716-26 (2006) Article DOI: 10.1021/jm050293c BindingDB Entry DOI: 10.7270/Q2P84952 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149939 (US8975415, 221 | US9242973, 221) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 37.8 | n/a | 81.8 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149939 (US8975415, 221 | US9242973, 221) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 37.8 | -42.4 | 81.8 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149749 (US8975415, 27 | US9242973, 27) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 38.2 | n/a | 82.2 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149749 (US8975415, 27 | US9242973, 27) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 38.2 | -42.3 | 82.2 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149938 (US8975415, 220 | US9242973, 220) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 42.9 | -42.1 | 76.5 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149938 (US8975415, 220 | US9242973, 220) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 42.9 | n/a | 76.5 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149752 (US8975415, 30 | US9242973, 30) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 51.5 | -41.6 | 97.5 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149752 (US8975415, 30 | US9242973, 30) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 51.5 | n/a | 97.5 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149942 (US8975415, 224 | US9242973, 224) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 52.7 | -41.5 | 91.4 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149942 (US8975415, 224 | US9242973, 224) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 52.7 | n/a | 91.4 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149941 (US8975415, 223 | US9242973, 223) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 61.2 | n/a | 99.1 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149941 (US8975415, 223 | US9242973, 223) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 61.2 | -41.2 | 99.1 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149914 (US8975415, RP195 | US9242973, 195) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 64.5 | -41.0 | 109 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149914 (US8975415, RP195 | US9242973, 195) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 64.5 | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149920 (US8975415, RP201 | US8975415, RP203 | US9242973, R...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 67.6 | -40.9 | 109 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149920 (US8975415, RP201 | US8975415, RP203 | US9242973, R...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 67.6 | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149920 (US8975415, RP201 | US8975415, RP203 | US9242973, R...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 71.1 | -40.8 | 113 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149920 (US8975415, RP201 | US8975415, RP203 | US9242973, R...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 71.1 | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149916 (US8975415, RP197 | US9242973, 197) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 72 | -40.8 | 118 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149916 (US8975415, RP197 | US9242973, 197) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 72 | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149943 (US8975415, 227 | US9242973, 227) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 79.2 | -40.5 | 107 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149943 (US8975415, 227 | US9242973, 227) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 79.2 | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149924 (US8975415, RP205 | US9242973, RP205) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 82.5 | -40.4 | 126 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149924 (US8975415, RP205 | US9242973, RP205) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 82.5 | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149909 (US8975415, RP190 | US9242973, 190) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 83.5 | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149909 (US8975415, RP190 | US9242973, 190) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 83.5 | -40.4 | 125 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149811 (US8975415, RP92 | US9242973, RP92) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 87.9 | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149811 (US8975415, RP92 | US9242973, RP92) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 87.9 | -40.3 | 124 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149829 (US8975415, RP110 | US9242973, RP110) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 90.4 | -40.2 | 137 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149829 (US8975415, RP110 | US9242973, RP110) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 90.4 | n/a | 137 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149940 (US8975415, 222 | US9242973, 222) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 91.5 | -40.2 | 138 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149940 (US8975415, 222 | US9242973, 222) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 91.5 | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149919 (US8975415, RP200 | US8975415, RP202 | US9242973, R...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 92.1 | -40.2 | 128 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149919 (US8975415, RP200 | US8975415, RP202 | US9242973, R...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 92.1 | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149805 (US8975415, RP86 | US9242973, RP86) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 107 | -39.8 | 143 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149805 (US8975415, RP86 | US9242973, RP86) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 107 | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149919 (US8975415, RP200 | US8975415, RP202 | US9242973, R...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 113 | -39.7 | 145 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149919 (US8975415, RP200 | US8975415, RP202 | US9242973, R...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 113 | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149750 (US8975415, 28 | US9242973, 28) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 117 | -39.6 | 154 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149750 (US8975415, 28 | US9242973, 28) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 117 | n/a | 154 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149828 (US8975415, RP109 | US9242973, RP109) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 120 | -39.5 | 152 | n/a | n/a | n/a | n/a | 4.4 | 25 |
COMENTIS, INC. US Patent | Assay Description Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi... | US Patent US9242973 (2016) BindingDB Entry DOI: 10.7270/Q29W0D9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM149828 (US8975415, RP109 | US9242973, RP109) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 120 | n/a | 152 | n/a | n/a | n/a | n/a | n/a | n/a |
CoMentis, Inc. US Patent | Assay Description Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo... | US Patent US8975415 (2015) BindingDB Entry DOI: 10.7270/Q2SB44GN | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 932 total ) | Next | Last >> |