Compile Data Set for Download or QSAR

Found 2950 hits with Last Name = 'sappey' and Initial = 'kc'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118664 (US11059828, Example 317 | US11667644, Example 317 ...) Show SMILES Cc1nc(nc(C)c1Cl)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C21H21ClFN7O/c1-12-19(22)13(2)27-21(26-12)29-10-14-8-28(9-15(14)11-29)20(31)18-16(23)4-3-5-17(18)30-24-6-7-25-30/h3-7,14-15H,8-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118664 (US11059828, Example 317 | US11667644, Example 317 ...) Show SMILES Cc1nc(nc(C)c1Cl)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C21H21ClFN7O/c1-12-19(22)13(2)27-21(26-12)29-10-14-8-28(9-15(14)11-29)20(31)18-16(23)4-3-5-17(18)30-24-6-7-25-30/h3-7,14-15H,8-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118664 (US11059828, Example 317 | US11667644, Example 317 ...) Show SMILES Cc1nc(nc(C)c1Cl)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C21H21ClFN7O/c1-12-19(22)13(2)27-21(26-12)29-10-14-8-28(9-15(14)11-29)20(31)18-16(23)4-3-5-17(18)30-24-6-7-25-30/h3-7,14-15H,8-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118664 (US11059828, Example 317 | US11667644, Example 317 ...) Show SMILES Cc1nc(nc(C)c1Cl)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C21H21ClFN7O/c1-12-19(22)13(2)27-21(26-12)29-10-14-8-28(9-15(14)11-29)20(31)18-16(23)4-3-5-17(18)30-24-6-7-25-30/h3-7,14-15H,8-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118641 (US11059828, Example 294 | US11667644, Example 294 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-13-14(2)26-22(27-15(13)3)29-11-16-9-28(10-17(16)12-29)21(31)20-18(23)5-4-6-19(20)30-24-7-8-25-30/h4-8,16-17H,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118667 (US11059828, Example 320 | US11667644, Example 320 ...) Show SMILES Cc1nc(nc(C)c1Cl)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1ncn(C)n1 Show InChI InChI=1S/C22H24ClN7O/c1-13-19(23)14(2)26-22(25-13)30-10-15-8-29(9-16(15)11-30)21(31)18-7-5-4-6-17(18)20-24-12-28(3)27-20/h4-7,12,15-16H,8-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118641 (US11059828, Example 294 | US11667644, Example 294 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-13-14(2)26-22(27-15(13)3)29-11-16-9-28(10-17(16)12-29)21(31)20-18(23)5-4-6-19(20)30-24-7-8-25-30/h4-8,16-17H,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118641 (US11059828, Example 294 | US11667644, Example 294 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-13-14(2)26-22(27-15(13)3)29-11-16-9-28(10-17(16)12-29)21(31)20-18(23)5-4-6-19(20)30-24-7-8-25-30/h4-8,16-17H,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118641 (US11059828, Example 294 | US11667644, Example 294 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-13-14(2)26-22(27-15(13)3)29-11-16-9-28(10-17(16)12-29)21(31)20-18(23)5-4-6-19(20)30-24-7-8-25-30/h4-8,16-17H,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118667 (US11059828, Example 320 | US11667644, Example 320 ...) Show SMILES Cc1nc(nc(C)c1Cl)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1ncn(C)n1 Show InChI InChI=1S/C22H24ClN7O/c1-13-19(23)14(2)26-22(25-13)30-10-15-8-29(9-16(15)11-30)21(31)18-7-5-4-6-17(18)20-24-12-28(3)27-20/h4-7,12,15-16H,8-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118667 (US11059828, Example 320 | US11667644, Example 320 ...) Show SMILES Cc1nc(nc(C)c1Cl)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1ncn(C)n1 Show InChI InChI=1S/C22H24ClN7O/c1-13-19(23)14(2)26-22(25-13)30-10-15-8-29(9-16(15)11-30)21(31)18-7-5-4-6-17(18)20-24-12-28(3)27-20/h4-7,12,15-16H,8-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118667 (US11059828, Example 320 | US11667644, Example 320 ...) Show SMILES Cc1nc(nc(C)c1Cl)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1ncn(C)n1 Show InChI InChI=1S/C22H24ClN7O/c1-13-19(23)14(2)26-22(25-13)30-10-15-8-29(9-16(15)11-30)21(31)18-7-5-4-6-17(18)20-24-12-28(3)27-20/h4-7,12,15-16H,8-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118665 (US11059828, Example 318 | US11667644, Example 318 ...) Show SMILES Cc1noc(n1)-c1ccccc1C(=O)N1CC2CN(CC2C1)c1nc(C)c(Cl)c(C)n1 Show InChI InChI=1S/C22H23ClN6O2/c1-12-19(23)13(2)25-22(24-12)29-10-15-8-28(9-16(15)11-29)21(30)18-7-5-4-6-17(18)20-26-14(3)27-31-20/h4-7,15-16H,8-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118665 (US11059828, Example 318 | US11667644, Example 318 ...) Show SMILES Cc1noc(n1)-c1ccccc1C(=O)N1CC2CN(CC2C1)c1nc(C)c(Cl)c(C)n1 Show InChI InChI=1S/C22H23ClN6O2/c1-12-19(23)13(2)25-22(24-12)29-10-15-8-28(9-16(15)11-29)21(30)18-7-5-4-6-17(18)20-26-14(3)27-31-20/h4-7,15-16H,8-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118665 (US11059828, Example 318 | US11667644, Example 318 ...) Show SMILES Cc1noc(n1)-c1ccccc1C(=O)N1CC2CN(CC2C1)c1nc(C)c(Cl)c(C)n1 Show InChI InChI=1S/C22H23ClN6O2/c1-12-19(23)13(2)25-22(24-12)29-10-15-8-28(9-16(15)11-29)21(30)18-7-5-4-6-17(18)20-26-14(3)27-31-20/h4-7,15-16H,8-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118665 (US11059828, Example 318 | US11667644, Example 318 ...) Show SMILES Cc1noc(n1)-c1ccccc1C(=O)N1CC2CN(CC2C1)c1nc(C)c(Cl)c(C)n1 Show InChI InChI=1S/C22H23ClN6O2/c1-12-19(23)13(2)25-22(24-12)29-10-15-8-28(9-16(15)11-29)21(30)18-7-5-4-6-17(18)20-26-14(3)27-31-20/h4-7,15-16H,8-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118644 (US11059828, Example 297 | US11667644, Example 297 ...) Show SMILES CCc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-3-17-9-14(2)26-22(27-17)29-12-15-10-28(11-16(15)13-29)21(31)20-18(23)5-4-6-19(20)30-24-7-8-25-30/h4-9,15-16H,3,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118644 (US11059828, Example 297 | US11667644, Example 297 ...) Show SMILES CCc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-3-17-9-14(2)26-22(27-17)29-12-15-10-28(11-16(15)13-29)21(31)20-18(23)5-4-6-19(20)30-24-7-8-25-30/h4-9,15-16H,3,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118644 (US11059828, Example 297 | US11667644, Example 297 ...) Show SMILES CCc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-3-17-9-14(2)26-22(27-17)29-12-15-10-28(11-16(15)13-29)21(31)20-18(23)5-4-6-19(20)30-24-7-8-25-30/h4-9,15-16H,3,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118644 (US11059828, Example 297 | US11667644, Example 297 ...) Show SMILES CCc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-3-17-9-14(2)26-22(27-17)29-12-15-10-28(11-16(15)13-29)21(31)20-18(23)5-4-6-19(20)30-24-7-8-25-30/h4-9,15-16H,3,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118652 (US11059828, Example 305 | US11667644, Example 305 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1nnc[nH]1 Show InChI InChI=1S/C22H25N7O/c1-13-14(2)25-22(26-15(13)3)29-10-16-8-28(9-17(16)11-29)21(30)19-7-5-4-6-18(19)20-23-12-24-27-20/h4-7,12,16-17H,8-11H2,1-3H3,(H,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118420 (US11059828, Example 73 | US11667644, Example 73 | ...) Show SMILES Cc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-c1ncccn1 Show InChI InChI=1S/C23H23FN6O/c1-14-9-15(2)28-23(27-14)30-12-16-10-29(11-17(16)13-30)22(31)20-18(5-3-6-19(20)24)21-25-7-4-8-26-21/h3-9,16-17H,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118658 (US11059828, Example 311 | US11667644, Example 311 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1ncn(C)n1 Show InChI InChI=1S/C23H27N7O/c1-14-15(2)25-23(26-16(14)3)30-11-17-9-29(10-18(17)12-30)22(31)20-8-6-5-7-19(20)21-24-13-28(4)27-21/h5-8,13,17-18H,9-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118660 (US11059828, Example 313 | US11667644, Example 313 ...) Show SMILES Cc1nc(nc2CCCc12)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C23H24FN7O/c1-14-17-4-2-6-19(17)28-23(27-14)30-12-15-10-29(11-16(15)13-30)22(32)21-18(24)5-3-7-20(21)31-25-8-9-26-31/h3,5,7-9,15-16H,2,4,6,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118586 (US11059828, Example 239 | US11667644, Example 239 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1cccc(F)c1-c1ncccn1 Show InChI InChI=1S/C24H25FN6O/c1-14-15(2)28-24(29-16(14)3)31-12-17-10-30(11-18(17)13-31)23(32)19-6-4-7-20(25)21(19)22-26-8-5-9-27-22/h4-9,17-18H,10-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118587 (US11059828, Example 240 | US11667644, Example 240 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1cccc(F)c1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-13-14(2)26-22(27-15(13)3)29-11-16-9-28(10-17(16)12-29)21(31)18-5-4-6-19(23)20(18)30-24-7-8-25-30/h4-8,16-17H,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118390 (US11059828, Example 43 | US11667644, Example 43 | ...) Show SMILES Cc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1cccs1 Show InChI InChI=1S/C23H24N4OS/c1-15-10-16(2)25-23(24-15)27-13-17-11-26(12-18(17)14-27)22(28)20-7-4-3-6-19(20)21-8-5-9-29-21/h3-10,17-18H,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118420 (US11059828, Example 73 | US11667644, Example 73 | ...) Show SMILES Cc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-c1ncccn1 Show InChI InChI=1S/C23H23FN6O/c1-14-9-15(2)28-23(27-14)30-12-16-10-29(11-17(16)13-30)22(31)20-18(5-3-6-19(20)24)21-25-7-4-8-26-21/h3-9,16-17H,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2M330QS
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118390 (US11059828, Example 43 | US11667644, Example 43 | ...) Show SMILES Cc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1cccs1 Show InChI InChI=1S/C23H24N4OS/c1-15-10-16(2)25-23(24-15)27-13-17-11-26(12-18(17)14-27)22(28)20-7-4-3-6-19(20)21-8-5-9-29-21/h3-10,17-18H,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118420 (US11059828, Example 73 | US11667644, Example 73 | ...) Show SMILES Cc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-c1ncccn1 Show InChI InChI=1S/C23H23FN6O/c1-14-9-15(2)28-23(27-14)30-12-16-10-29(11-17(16)13-30)22(31)20-18(5-3-6-19(20)24)21-25-7-4-8-26-21/h3-9,16-17H,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118586 (US11059828, Example 239 | US11667644, Example 239 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1cccc(F)c1-c1ncccn1 Show InChI InChI=1S/C24H25FN6O/c1-14-15(2)28-24(29-16(14)3)31-12-17-10-30(11-18(17)13-31)23(32)19-6-4-7-20(25)21(19)22-26-8-5-9-27-22/h4-9,17-18H,10-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118587 (US11059828, Example 240 | US11667644, Example 240 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1cccc(F)c1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-13-14(2)26-22(27-15(13)3)29-11-16-9-28(10-17(16)12-29)21(31)18-5-4-6-19(23)20(18)30-24-7-8-25-30/h4-8,16-17H,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118652 (US11059828, Example 305 | US11667644, Example 305 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1nnc[nH]1 Show InChI InChI=1S/C22H25N7O/c1-13-14(2)25-22(26-15(13)3)29-10-16-8-28(9-17(16)11-29)21(30)19-7-5-4-6-18(19)20-23-12-24-27-20/h4-7,12,16-17H,8-11H2,1-3H3,(H,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118656 (US11059828, Example 309 | US11667644, Example 309 ...) Show SMILES Cc1noc(n1)-c1ccccc1C(=O)N1CC2CN(CC2C1)c1nc(C)c(C)c(C)n1 Show InChI InChI=1S/C23H26N6O2/c1-13-14(2)24-23(25-15(13)3)29-11-17-9-28(10-18(17)12-29)22(30)20-8-6-5-7-19(20)21-26-16(4)27-31-21/h5-8,17-18H,9-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118658 (US11059828, Example 311 | US11667644, Example 311 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1ncn(C)n1 Show InChI InChI=1S/C23H27N7O/c1-14-15(2)25-23(26-16(14)3)30-11-17-9-29(10-18(17)12-30)22(31)20-8-6-5-7-19(20)21-24-13-28(4)27-21/h5-8,13,17-18H,9-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118660 (US11059828, Example 313 | US11667644, Example 313 ...) Show SMILES Cc1nc(nc2CCCc12)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C23H24FN7O/c1-14-17-4-2-6-19(17)28-23(27-14)30-12-15-10-29(11-16(15)13-30)22(32)21-18(24)5-3-7-20(21)31-25-8-9-26-31/h3,5,7-9,15-16H,2,4,6,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T156TJ
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118390 (US11059828, Example 43 | US11667644, Example 43 | ...) Show SMILES Cc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1cccs1 Show InChI InChI=1S/C23H24N4OS/c1-15-10-16(2)25-23(24-15)27-13-17-11-26(12-18(17)14-27)22(28)20-7-4-3-6-19(20)21-8-5-9-29-21/h3-10,17-18H,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118586 (US11059828, Example 239 | US11667644, Example 239 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1cccc(F)c1-c1ncccn1 Show InChI InChI=1S/C24H25FN6O/c1-14-15(2)28-24(29-16(14)3)31-12-17-10-30(11-18(17)13-31)23(32)19-6-4-7-20(25)21(19)22-26-8-5-9-27-22/h4-9,17-18H,10-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118587 (US11059828, Example 240 | US11667644, Example 240 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1cccc(F)c1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-13-14(2)26-22(27-15(13)3)29-11-16-9-28(10-17(16)12-29)21(31)18-5-4-6-19(23)20(18)30-24-7-8-25-30/h4-8,16-17H,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118652 (US11059828, Example 305 | US11667644, Example 305 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1nnc[nH]1 Show InChI InChI=1S/C22H25N7O/c1-13-14(2)25-22(26-15(13)3)29-10-16-8-28(9-17(16)11-29)21(30)19-7-5-4-6-18(19)20-23-12-24-27-20/h4-7,12,16-17H,8-11H2,1-3H3,(H,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118656 (US11059828, Example 309 | US11667644, Example 309 ...) Show SMILES Cc1noc(n1)-c1ccccc1C(=O)N1CC2CN(CC2C1)c1nc(C)c(C)c(C)n1 Show InChI InChI=1S/C23H26N6O2/c1-13-14(2)24-23(25-15(13)3)29-11-17-9-28(10-18(17)12-29)22(30)20-8-6-5-7-19(20)21-26-16(4)27-31-21/h5-8,17-18H,9-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118658 (US11059828, Example 311 | US11667644, Example 311 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1ncn(C)n1 Show InChI InChI=1S/C23H27N7O/c1-14-15(2)25-23(26-16(14)3)30-11-17-9-29(10-18(17)12-30)22(31)20-8-6-5-7-19(20)21-24-13-28(4)27-21/h5-8,13,17-18H,9-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118660 (US11059828, Example 313 | US11667644, Example 313 ...) Show SMILES Cc1nc(nc2CCCc12)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C23H24FN7O/c1-14-17-4-2-6-19(17)28-23(27-14)30-12-15-10-29(11-16(15)13-30)22(32)21-18(24)5-3-7-20(21)31-25-8-9-26-31/h3,5,7-9,15-16H,2,4,6,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118660 (US11059828, Example 313 | US11667644, Example 313 ...) Show SMILES Cc1nc(nc2CCCc12)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1 Show InChI InChI=1S/C23H24FN7O/c1-14-17-4-2-6-19(17)28-23(27-14)30-12-15-10-29(11-16(15)13-30)22(32)21-18(24)5-3-7-20(21)31-25-8-9-26-31/h3,5,7-9,15-16H,2,4,6,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118420 (US11059828, Example 73 | US11667644, Example 73 | ...) Show SMILES Cc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-c1ncccn1 Show InChI InChI=1S/C23H23FN6O/c1-14-9-15(2)28-23(27-14)30-12-16-10-29(11-17(16)13-30)22(31)20-18(5-3-6-19(20)24)21-25-7-4-8-26-21/h3-9,16-17H,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PK0K9R
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118586 (US11059828, Example 239 | US11667644, Example 239 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1cccc(F)c1-c1ncccn1 Show InChI InChI=1S/C24H25FN6O/c1-14-15(2)28-24(29-16(14)3)31-12-17-10-30(11-18(17)13-31)23(32)19-6-4-7-20(25)21(19)22-26-8-5-9-27-22/h4-9,17-18H,10-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118587 (US11059828, Example 240 | US11667644, Example 240 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1cccc(F)c1-n1nccn1 Show InChI InChI=1S/C22H24FN7O/c1-13-14(2)26-22(27-15(13)3)29-11-16-9-28(10-17(16)12-29)21(31)18-5-4-6-19(23)20(18)30-24-7-8-25-30/h4-8,16-17H,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118652 (US11059828, Example 305 | US11667644, Example 305 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1nnc[nH]1 Show InChI InChI=1S/C22H25N7O/c1-13-14(2)25-22(26-15(13)3)29-10-16-8-28(9-17(16)11-29)21(30)19-7-5-4-6-18(19)20-23-12-24-27-20/h4-7,12,16-17H,8-11H2,1-3H3,(H,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118656 (US11059828, Example 309 | US11667644, Example 309 ...) Show SMILES Cc1noc(n1)-c1ccccc1C(=O)N1CC2CN(CC2C1)c1nc(C)c(C)c(C)n1 Show InChI InChI=1S/C23H26N6O2/c1-13-14(2)24-23(25-15(13)3)29-11-17-9-28(10-18(17)12-29)22(30)20-8-6-5-7-19(20)21-26-16(4)27-31-21/h5-8,17-18H,9-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM118658 (US11059828, Example 311 | US11667644, Example 311 ...) Show SMILES Cc1nc(nc(C)c1C)N1CC2CN(CC2C1)C(=O)c1ccccc1-c1ncn(C)n1 Show InChI InChI=1S/C23H27N7O/c1-14-15(2)25-23(26-16(14)3)30-11-17-9-29(10-18(17)12-30)22(31)20-8-6-5-7-19(20)21-24-13-28(4)27-21/h5-8,13,17-18H,9-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica US Patent					Assay Description The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...				US Patent US8653263 (2014) BindingDB Entry DOI: 10.7270/Q2BR8QV7
					More data for this Ligand-Target Pair

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