Compile Data Set for Download or QSAR

Found 130 hits with Last Name = 'schulze' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129353 (US8802686, 11) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)CCO)ncc1C(F)(F)F |r| Show InChI InChI=1S/C17H20F3N3O5S/c1-10(25)11(2)28-15-14(17(18,19)20)9-21-16(23-15)22-12-3-5-13(6-4-12)29(26,27)8-7-24/h3-6,9-11,24-25H,7-8H2,1-2H3,(H,21,22,23)/t10-,11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129353 (US8802686, 11) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)CCO)ncc1C(F)(F)F |r| Show InChI InChI=1S/C17H20F3N3O5S/c1-10(25)11(2)28-15-14(17(18,19)20)9-21-16(23-15)22-12-3-5-13(6-4-12)29(26,27)8-7-24/h3-6,9-11,24-25H,7-8H2,1-2H3,(H,21,22,23)/t10-,11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM6145 (US8802686, 2 | US8802686, C2) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H18F3N3O4S/c1-9(23)10(2)26-14-13(16(17,18)19)8-20-15(22-14)21-11-4-6-12(7-5-11)27(3,24)25/h4-10,23H,1-3H3,(H,20,21,22)/t9-,10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM6145 (US8802686, 2 | US8802686, C2) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H18F3N3O4S/c1-9(23)10(2)26-14-13(16(17,18)19)8-20-15(22-14)21-11-4-6-12(7-5-11)27(3,24)25/h4-10,23H,1-3H3,(H,20,21,22)/t9-,10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129351 (US8802686, 9) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C(C)C)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H22F3N3O4S/c1-10(2)29(26,27)14-7-5-13(6-8-14)23-17-22-9-15(18(19,20)21)16(24-17)28-12(4)11(3)25/h5-12,25H,1-4H3,(H,22,23,24)/t11-,12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM6131 (US8802686, 1 | US8802686, C1) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H20F3N3O4S/c1-10(25)11(2)28-16-15(18(19,20)21)9-22-17(24-16)23-12-3-5-13(6-4-12)29(26,27)14-7-8-14/h3-6,9-11,14,25H,7-8H2,1-2H3,(H,22,23,24)/t10-,11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM6145 (US8802686, 2 | US8802686, C2) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H18F3N3O4S/c1-9(23)10(2)26-14-13(16(17,18)19)8-20-15(22-14)21-11-4-6-12(7-5-11)27(3,24)25/h4-10,23H,1-3H3,(H,20,21,22)/t9-,10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM6131 (US8802686, 1 | US8802686, C1) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H20F3N3O4S/c1-10(25)11(2)28-16-15(18(19,20)21)9-22-17(24-16)23-12-3-5-13(6-4-12)29(26,27)14-7-8-14/h3-6,9-11,14,25H,7-8H2,1-2H3,(H,22,23,24)/t10-,11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM6192 (US8802686, 3 | US8802686, C3) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C17H20F3N3O4S/c1-10(16(2,3)24)27-14-13(17(18,19)20)9-21-15(23-14)22-11-5-7-12(8-6-11)28(4,25)26/h5-10,24H,1-4H3,(H,21,22,23)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM6145 (US8802686, 2 | US8802686, C2) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H18F3N3O4S/c1-9(23)10(2)26-14-13(16(17,18)19)8-20-15(22-14)21-11-4-6-12(7-5-11)27(3,24)25/h4-10,23H,1-3H3,(H,20,21,22)/t9-,10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM6192 (US8802686, 3 | US8802686, C3) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C17H20F3N3O4S/c1-10(16(2,3)24)27-14-13(17(18,19)20)9-21-15(23-14)22-11-5-7-12(8-6-11)28(4,25)26/h5-10,24H,1-4H3,(H,21,22,23)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129350 (US8802686, 8) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(=O)(=O)CC=C)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C19H22F3N3O4S/c1-5-10-30(27,28)14-8-6-13(7-9-14)24-17-23-11-15(19(20,21)22)16(25-17)29-12(2)18(3,4)26/h5-9,11-12,26H,1,10H2,2-4H3,(H,23,24,25)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129351 (US8802686, 9) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C(C)C)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H22F3N3O4S/c1-10(2)29(26,27)14-7-5-13(6-8-14)23-17-22-9-15(18(19,20)21)16(24-17)28-12(4)11(3)25/h5-12,25H,1-4H3,(H,22,23,24)/t11-,12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129348 (US8802686, 6) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C(F)F)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H16F5N3O4S/c1-8(25)9(2)28-13-12(16(19,20)21)7-22-15(24-13)23-10-3-5-11(6-4-10)29(26,27)14(17)18/h3-9,14,25H,1-2H3,(H,22,23,24)/t8-,9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM6192 (US8802686, 3 | US8802686, C3) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C17H20F3N3O4S/c1-10(16(2,3)24)27-14-13(17(18,19)20)9-21-15(23-14)22-11-5-7-12(8-6-11)28(4,25)26/h5-10,24H,1-4H3,(H,21,22,23)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129354 (US8802686, 12) Show SMILES COC[C@@H](C)Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H18F3N3O4S/c1-10(9-25-2)26-14-13(16(17,18)19)8-20-15(22-14)21-11-4-6-12(7-5-11)27(3,23)24/h4-8,10H,9H2,1-3H3,(H,20,21,22)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM6131 (US8802686, 1 | US8802686, C1) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H20F3N3O4S/c1-10(25)11(2)28-16-15(18(19,20)21)9-22-17(24-16)23-12-3-5-13(6-4-12)29(26,27)14-7-8-14/h3-6,9-11,14,25H,7-8H2,1-2H3,(H,22,23,24)/t10-,11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM6131 (US8802686, 1 | US8802686, C1) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H20F3N3O4S/c1-10(25)11(2)28-16-15(18(19,20)21)9-22-17(24-16)23-12-3-5-13(6-4-12)29(26,27)14-7-8-14/h3-6,9-11,14,25H,7-8H2,1-2H3,(H,22,23,24)/t10-,11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM6131 (US8802686, 1 | US8802686, C1) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H20F3N3O4S/c1-10(25)11(2)28-16-15(18(19,20)21)9-22-17(24-16)23-12-3-5-13(6-4-12)29(26,27)14-7-8-14/h3-6,9-11,14,25H,7-8H2,1-2H3,(H,22,23,24)/t10-,11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant CDK4 and CycD1-GST fusion proteins, purified from baculovirus-infected insect cells (Sf9), were purchased from ProQinase GmbH, Freiburg. ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129346 (US8802686, 4) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C19H22F3N3O4S/c1-11(18(2,3)26)29-16-15(19(20,21)22)10-23-17(25-16)24-12-4-6-13(7-5-12)30(27,28)14-8-9-14/h4-7,10-11,14,26H,8-9H2,1-3H3,(H,23,24,25)/t11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129349 (US8802686, 7) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CCCC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C20H24F3N3O4S/c1-12(27)13(2)30-18-17(20(21,22)23)11-24-19(26-18)25-14-7-9-16(10-8-14)31(28,29)15-5-3-4-6-15/h7-13,15,27H,3-6H2,1-2H3,(H,24,25,26)/t12-,13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129349 (US8802686, 7) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CCCC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C20H24F3N3O4S/c1-12(27)13(2)30-18-17(20(21,22)23)11-24-19(26-18)25-14-7-9-16(10-8-14)31(28,29)15-5-3-4-6-15/h7-13,15,27H,3-6H2,1-2H3,(H,24,25,26)/t12-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129348 (US8802686, 6) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C(F)F)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H16F5N3O4S/c1-8(25)9(2)28-13-12(16(19,20)21)7-22-15(24-13)23-10-3-5-11(6-4-10)29(26,27)14(17)18/h3-9,14,25H,1-2H3,(H,22,23,24)/t8-,9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM6192 (US8802686, 3 | US8802686, C3) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C17H20F3N3O4S/c1-10(16(2,3)24)27-14-13(17(18,19)20)9-21-15(23-14)22-11-5-7-12(8-6-11)28(4,25)26/h5-10,24H,1-4H3,(H,21,22,23)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant CDK4 and CycD1-GST fusion proteins, purified from baculovirus-infected insect cells (Sf9), were purchased from ProQinase GmbH, Freiburg. ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM6145 (US8802686, 2 | US8802686, C2) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H18F3N3O4S/c1-9(23)10(2)26-14-13(16(17,18)19)8-20-15(22-14)21-11-4-6-12(7-5-11)27(3,24)25/h4-10,23H,1-3H3,(H,20,21,22)/t9-,10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant CDK4 and CycD1-GST fusion proteins, purified from baculovirus-infected insect cells (Sf9), were purchased from ProQinase GmbH, Freiburg. ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129355 (US8802686, 13) Show SMILES CS(=O)(=O)c1ccc(Nc2ncc(c(OCC#C)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C15H12F3N3O3S/c1-3-8-24-13-12(15(16,17)18)9-19-14(21-13)20-10-4-6-11(7-5-10)25(2,22)23/h1,4-7,9H,8H2,2H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM6192 (US8802686, 3 | US8802686, C3) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C17H20F3N3O4S/c1-10(16(2,3)24)27-14-13(17(18,19)20)9-21-15(23-14)22-11-5-7-12(8-6-11)28(4,25)26/h5-10,24H,1-4H3,(H,21,22,23)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM6145 (US8802686, 2 | US8802686, C2) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H18F3N3O4S/c1-9(23)10(2)26-14-13(16(17,18)19)8-20-15(22-14)21-11-4-6-12(7-5-11)27(3,24)25/h4-10,23H,1-3H3,(H,20,21,22)/t9-,10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant CDK4 and CycD1-GST fusion proteins, purified from baculovirus-infected insect cells (Sf9), were purchased from ProQinase GmbH, Freiburg. ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129347 (US8802686, 5) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)c2ccccc2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C21H20F3N3O4S/c1-13(28)14(2)31-19-18(21(22,23)24)12-25-20(27-19)26-15-8-10-17(11-9-15)32(29,30)16-6-4-3-5-7-16/h3-14,28H,1-2H3,(H,25,26,27)/t13-,14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129346 (US8802686, 4) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C19H22F3N3O4S/c1-11(18(2,3)26)29-16-15(19(20,21)22)10-23-17(25-16)24-12-4-6-13(7-5-12)30(27,28)14-8-9-14/h4-7,10-11,14,26H,8-9H2,1-3H3,(H,23,24,25)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129347 (US8802686, 5) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)c2ccccc2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C21H20F3N3O4S/c1-13(28)14(2)31-19-18(21(22,23)24)12-25-20(27-19)26-15-8-10-17(11-9-15)32(29,30)16-6-4-3-5-7-16/h3-14,28H,1-2H3,(H,25,26,27)/t13-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129350 (US8802686, 8) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(=O)(=O)CC=C)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C19H22F3N3O4S/c1-5-10-30(27,28)14-8-6-13(7-9-14)24-17-23-11-15(19(20,21)22)16(25-17)29-12(2)18(3,4)26/h5-9,11-12,26H,1,10H2,2-4H3,(H,23,24,25)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129352 (US8802686, 10) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(=O)(=O)CC#C)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C19H20F3N3O4S/c1-5-10-30(27,28)14-8-6-13(7-9-14)24-17-23-11-15(19(20,21)22)16(25-17)29-12(2)18(3,4)26/h1,6-9,11-12,26H,10H2,2-4H3,(H,23,24,25)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129357 (US8802686, 15) Show SMILES CS(=O)(=O)c1ccc(Nc2ncc(c(OCC=C)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C15H14F3N3O3S/c1-3-8-24-13-12(15(16,17)18)9-19-14(21-13)20-10-4-6-11(7-5-10)25(2,22)23/h3-7,9H,1,8H2,2H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129354 (US8802686, 12) Show SMILES COC[C@@H](C)Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H18F3N3O4S/c1-10(9-25-2)26-14-13(16(17,18)19)8-20-15(22-14)21-11-4-6-12(7-5-11)27(3,23)24/h4-8,10H,9H2,1-3H3,(H,20,21,22)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM6131 (US8802686, 1 | US8802686, C1) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H20F3N3O4S/c1-10(25)11(2)28-16-15(18(19,20)21)9-22-17(24-16)23-12-3-5-13(6-4-12)29(26,27)14-7-8-14/h3-6,9-11,14,25H,7-8H2,1-2H3,(H,22,23,24)/t10-,11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	5.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM6131 (US8802686, 1 | US8802686, C1) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H20F3N3O4S/c1-10(25)11(2)28-16-15(18(19,20)21)9-22-17(24-16)23-12-3-5-13(6-4-12)29(26,27)14-7-8-14/h3-6,9-11,14,25H,7-8H2,1-2H3,(H,22,23,24)/t10-,11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	7.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant CDK4 and CycD1-GST fusion proteins, purified from baculovirus-infected insect cells (Sf9), were purchased from ProQinase GmbH, Freiburg. ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM6192 (US8802686, 3 | US8802686, C3) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C17H20F3N3O4S/c1-10(16(2,3)24)27-14-13(17(18,19)20)9-21-15(23-14)22-11-5-7-12(8-6-11)28(4,25)26/h5-10,24H,1-4H3,(H,21,22,23)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	7.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant CDK4 and CycD1-GST fusion proteins, purified from baculovirus-infected insect cells (Sf9), were purchased from ProQinase GmbH, Freiburg. ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129352 (US8802686, 10) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(=O)(=O)CC#C)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C19H20F3N3O4S/c1-5-10-30(27,28)14-8-6-13(7-9-14)24-17-23-11-15(19(20,21)22)16(25-17)29-12(2)18(3,4)26/h1,6-9,11-12,26H,10H2,2-4H3,(H,23,24,25)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM6145 (US8802686, 2 | US8802686, C2) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H18F3N3O4S/c1-9(23)10(2)26-14-13(16(17,18)19)8-20-15(22-14)21-11-4-6-12(7-5-11)27(3,24)25/h4-10,23H,1-3H3,(H,20,21,22)/t9-,10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	92	n/a	n/a	n/a	n/a	5.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM129356 (US8802686, 14) Show SMILES CS(=O)(=O)c1ccc(Nc2ncc(c(OCCC(F)(F)F)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C15H13F6N3O3S/c1-28(25,26)10-4-2-9(3-5-10)23-13-22-8-11(15(19,20)21)12(24-13)27-7-6-14(16,17)18/h2-5,8H,6-7H2,1H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK2/CycE (50 mg/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 uM, and within ...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129355 (US8802686, 13) Show SMILES CS(=O)(=O)c1ccc(Nc2ncc(c(OCC#C)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C15H12F3N3O3S/c1-3-8-24-13-12(15(16,17)18)9-19-14(21-13)20-10-4-6-11(7-5-10)25(2,22)23/h1,4-7,9H,8H2,2H3,(H,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM129351 (US8802686, 9) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C(C)C)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H22F3N3O4S/c1-10(2)29(26,27)14-7-5-13(6-8-14)23-17-22-9-15(18(19,20)21)16(24-17)28-12(4)11(3)25/h5-12,25H,1-4H3,(H,22,23,24)/t11-,12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	5.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM129353 (US8802686, 11) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)CCO)ncc1C(F)(F)F |r| Show InChI InChI=1S/C17H20F3N3O5S/c1-10(25)11(2)28-15-14(17(18,19)20)9-21-16(23-15)22-12-3-5-13(6-4-12)29(26,27)8-7-24/h3-6,9-11,24-25H,7-8H2,1-2H3,(H,21,22,23)/t10-,11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	5.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM129346 (US8802686, 4) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C19H22F3N3O4S/c1-11(18(2,3)26)29-16-15(19(20,21)22)10-23-17(25-16)24-12-4-6-13(7-5-12)30(27,28)14-8-9-14/h4-7,10-11,14,26H,8-9H2,1-3H3,(H,23,24,25)/t11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	5.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM6192 (US8802686, 3 | US8802686, C3) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(C)(=O)=O)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C17H20F3N3O4S/c1-10(16(2,3)24)27-14-13(17(18,19)20)9-21-15(23-14)22-11-5-7-12(8-6-11)28(4,25)26/h5-10,24H,1-4H3,(H,21,22,23)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	5.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM129352 (US8802686, 10) Show SMILES C[C@@H](Oc1nc(Nc2ccc(cc2)S(=O)(=O)CC#C)ncc1C(F)(F)F)C(C)(C)O |r| Show InChI InChI=1S/C19H20F3N3O4S/c1-5-10-30(27,28)14-8-6-13(7-9-14)24-17-23-11-15(19(20,21)22)16(25-17)29-12(2)18(3,4)26/h1,6-9,11-12,26H,10H2,2-4H3,(H,23,24,25)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	5.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM129349 (US8802686, 7) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CCCC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C20H24F3N3O4S/c1-12(27)13(2)30-18-17(20(21,22)23)11-24-19(26-18)25-14-7-9-16(10-8-14)31(28,29)15-5-3-4-6-15/h7-13,15,27H,3-6H2,1-2H3,(H,24,25,26)/t12-,13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	5.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM6131 (US8802686, 1 | US8802686, C1) Show SMILES C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=O)(=O)C2CC2)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H20F3N3O4S/c1-10(25)11(2)28-16-15(18(19,20)21)9-22-17(24-16)23-12-3-5-13(6-4-12)29(26,27)14-7-8-14/h3-6,9-11,14,25H,7-8H2,1-2H3,(H,22,23,24)/t10-,11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	5.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description VEGF receptor tyrosine kinase (90 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substance...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM129357 (US8802686, 15) Show SMILES CS(=O)(=O)c1ccc(Nc2ncc(c(OCC=C)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C15H14F3N3O3S/c1-3-8-24-13-12(15(16,17)18)9-19-14(21-13)20-10-4-6-11(7-5-10)25(2,22)23/h3-7,9H,1,8H2,2H3,(H,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	280	n/a	n/a	n/a	n/a	8.0	22
Bayer Intellectual Property GmbH US Patent					Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...				US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1
					More data for this Ligand-Target Pair

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