Compile Data Set for Download or QSAR

Found 12 hits with Last Name = 'sepulchre' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283367 (CHEMBL82171 | Potassium; (5Z,8Z)-9-[(1S,6S)-6-((1Z...) Show SMILES CCCCC\C=C/C\C=C/[C@@H]1CC(C)=C(C)C[C@H]1\C=C/C\C=C/CCCC([O-])=O |t:13| Show InChI InChI=1S/C27H42O2/c1-4-5-6-7-8-9-12-15-18-25-21-23(2)24(3)22-26(25)19-16-13-10-11-14-17-20-27(28)29/h8-11,15-16,18-19,25-26H,4-7,12-14,17,20-22H2,1-3H3,(H,28,29)/p-1/b9-8-,11-10-,18-15-,19-16-/t25-,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23,187 for the formation of 5-HETE				Bioorg Med Chem Lett 4: 247-252 (1994) Article DOI: 10.1016/S0960-894X(01)80123-2 BindingDB Entry DOI: 10.7270/Q2CZ3732
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283366 (CHEMBL85370 | Potassium; (5Z,8Z)-9-[(1S,6R)-6-((1Z...) Show SMILES CCCCC\C=C/C\C=C/[C@H]1CC(C)=C(C)C[C@H]1\C=C/C\C=C/CCCC([O-])=O |t:13| Show InChI InChI=1S/C27H42O2/c1-4-5-6-7-8-9-12-15-18-25-21-23(2)24(3)22-26(25)19-16-13-10-11-14-17-20-27(28)29/h8-11,15-16,18-19,25-26H,4-7,12-14,17,20-22H2,1-3H3,(H,28,29)/p-1/b9-8-,11-10-,18-15-,19-16-/t25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23,187 for the formation of 5-HETE				Bioorg Med Chem Lett 4: 247-252 (1994) Article DOI: 10.1016/S0960-894X(01)80123-2 BindingDB Entry DOI: 10.7270/Q2CZ3732
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283367 (CHEMBL82171 | Potassium; (5Z,8Z)-9-[(1S,6S)-6-((1Z...) Show SMILES CCCCC\C=C/C\C=C/[C@@H]1CC(C)=C(C)C[C@H]1\C=C/C\C=C/CCCC([O-])=O |t:13| Show InChI InChI=1S/C27H42O2/c1-4-5-6-7-8-9-12-15-18-25-21-23(2)24(3)22-26(25)19-16-13-10-11-14-17-20-27(28)29/h8-11,15-16,18-19,25-26H,4-7,12-14,17,20-22H2,1-3H3,(H,28,29)/p-1/b9-8-,11-10-,18-15-,19-16-/t25-,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23,187 for the formation of leukotriene B4 (L...				Bioorg Med Chem Lett 4: 247-252 (1994) Article DOI: 10.1016/S0960-894X(01)80123-2 BindingDB Entry DOI: 10.7270/Q2CZ3732
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283368 (CHEMBL84549 | Potassium; (5Z,8Z)-9-[(1S,2S)-((1Z,4...) Show SMILES CCCCC\C=C/C\C=C/[C@@H]1C[C@H]1\C=C/C\C=C/CCCC([O-])=O Show InChI InChI=1S/C22H34O2/c1-2-3-4-5-6-7-10-13-16-20-19-21(20)17-14-11-8-9-12-15-18-22(23)24/h6-9,13-14,16-17,20-21H,2-5,10-12,15,18-19H2,1H3,(H,23,24)/p-1/b7-6-,9-8-,16-13-,17-14-/t20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23,187 for the formation of 5-HETE				Bioorg Med Chem Lett 4: 247-252 (1994) Article DOI: 10.1016/S0960-894X(01)80123-2 BindingDB Entry DOI: 10.7270/Q2CZ3732
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283368 (CHEMBL84549 | Potassium; (5Z,8Z)-9-[(1S,2S)-((1Z,4...) Show SMILES CCCCC\C=C/C\C=C/[C@@H]1C[C@H]1\C=C/C\C=C/CCCC([O-])=O Show InChI InChI=1S/C22H34O2/c1-2-3-4-5-6-7-10-13-16-20-19-21(20)17-14-11-8-9-12-15-18-22(23)24/h6-9,13-14,16-17,20-21H,2-5,10-12,15,18-19H2,1H3,(H,23,24)/p-1/b7-6-,9-8-,16-13-,17-14-/t20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23,187 for the formation of 5-HETE				Bioorg Med Chem Lett 4: 247-252 (1994) Article DOI: 10.1016/S0960-894X(01)80123-2 BindingDB Entry DOI: 10.7270/Q2CZ3732
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283366 (CHEMBL85370 | Potassium; (5Z,8Z)-9-[(1S,6R)-6-((1Z...) Show SMILES CCCCC\C=C/C\C=C/[C@H]1CC(C)=C(C)C[C@H]1\C=C/C\C=C/CCCC([O-])=O |t:13| Show InChI InChI=1S/C27H42O2/c1-4-5-6-7-8-9-12-15-18-25-21-23(2)24(3)22-26(25)19-16-13-10-11-14-17-20-27(28)29/h8-11,15-16,18-19,25-26H,4-7,12-14,17,20-22H2,1-3H3,(H,28,29)/p-1/b9-8-,11-10-,18-15-,19-16-/t25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23,187 for the formation of 5-HETE				Bioorg Med Chem Lett 4: 247-252 (1994) Article DOI: 10.1016/S0960-894X(01)80123-2 BindingDB Entry DOI: 10.7270/Q2CZ3732
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283368 (CHEMBL84549 | Potassium; (5Z,8Z)-9-[(1S,2S)-((1Z,4...) Show SMILES CCCCC\C=C/C\C=C/[C@@H]1C[C@H]1\C=C/C\C=C/CCCC([O-])=O Show InChI InChI=1S/C22H34O2/c1-2-3-4-5-6-7-10-13-16-20-19-21(20)17-14-11-8-9-12-15-18-22(23)24/h6-9,13-14,16-17,20-21H,2-5,10-12,15,18-19H2,1H3,(H,23,24)/p-1/b7-6-,9-8-,16-13-,17-14-/t20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23,187 for the formation of leukotriene B4 (L...				Bioorg Med Chem Lett 4: 247-252 (1994) Article DOI: 10.1016/S0960-894X(01)80123-2 BindingDB Entry DOI: 10.7270/Q2CZ3732
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283368 (CHEMBL84549 | Potassium; (5Z,8Z)-9-[(1S,2S)-((1Z,4...) Show SMILES CCCCC\C=C/C\C=C/[C@@H]1C[C@H]1\C=C/C\C=C/CCCC([O-])=O Show InChI InChI=1S/C22H34O2/c1-2-3-4-5-6-7-10-13-16-20-19-21(20)17-14-11-8-9-12-15-18-22(23)24/h6-9,13-14,16-17,20-21H,2-5,10-12,15,18-19H2,1H3,(H,23,24)/p-1/b7-6-,9-8-,16-13-,17-14-/t20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for the inhibition of 5-lipoxygenase of human PMN stimulated by calcium ionophore A-23,187 for the formation of leukotriene B4 (L...				Bioorg Med Chem Lett 4: 247-252 (1994) Article DOI: 10.1016/S0960-894X(01)80123-2 BindingDB Entry DOI: 10.7270/Q2CZ3732
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283370 ((6E,8E,10Z,13Z)-(R)-5-Hydroxy-nonadeca-6,8,10,13-t...) Show SMILES CCCCC\C=C/C\C=C/C=C/C=C/[C@H](O)CCCCN=O Show InChI InChI=1S/C19H31NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-19(21)17-14-15-18-20-22/h6-7,9-13,16,19,21H,2-5,8,14-15,17-18H2,1H3/b7-6-,10-9-,12-11+,16-13+/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase was evaluated in human polymorphonuclear leukocytes stimulated by calcium ionophore A-23,187 for formation of 5-HETE				Bioorg Med Chem Lett 4: 261-266 (1994) Article DOI: 10.1016/S0960-894X(01)80126-8 BindingDB Entry DOI: 10.7270/Q2862GCN
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283370 ((6E,8E,10Z,13Z)-(R)-5-Hydroxy-nonadeca-6,8,10,13-t...) Show SMILES CCCCC\C=C/C\C=C/C=C/C=C/[C@H](O)CCCCN=O Show InChI InChI=1S/C19H31NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-19(21)17-14-15-18-20-22/h6-7,9-13,16,19,21H,2-5,8,14-15,17-18H2,1H3/b7-6-,10-9-,12-11+,16-13+/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase was evaluated in human polymorphonuclear leukocytes stimulated by calcium ionophore A-23,187 for formation of LTB4				Bioorg Med Chem Lett 4: 261-266 (1994) Article DOI: 10.1016/S0960-894X(01)80126-8 BindingDB Entry DOI: 10.7270/Q2862GCN
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283369 ((6E,8E,10Z,13Z)-5-Hydroxy-nonadeca-6,8,10,13-tetra...) Show SMILES CCCCC\C=C/C\C=C/C=C/C=C/C(O)CCCCN=O Show InChI InChI=1S/C19H31NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-19(21)17-14-15-18-20-22/h6-7,9-13,16,19,21H,2-5,8,14-15,17-18H2,1H3/b7-6-,10-9-,12-11+,16-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase was evaluated in human polymorphonuclear leukocytes stimulated by calcium ionophore A-23,187 for formation of LTB4				Bioorg Med Chem Lett 4: 261-266 (1994) Article DOI: 10.1016/S0960-894X(01)80126-8 BindingDB Entry DOI: 10.7270/Q2862GCN
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50283369 ((6E,8E,10Z,13Z)-5-Hydroxy-nonadeca-6,8,10,13-tetra...) Show SMILES CCCCC\C=C/C\C=C/C=C/C=C/C(O)CCCCN=O Show InChI InChI=1S/C19H31NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-19(21)17-14-15-18-20-22/h6-7,9-13,16,19,21H,2-5,8,14-15,17-18H2,1H3/b7-6-,10-9-,12-11+,16-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase was evaluated in human polymorphonuclear leukocytes stimulated by calcium ionophore A-23,187 for formation of 5-HETE				Bioorg Med Chem Lett 4: 261-266 (1994) Article DOI: 10.1016/S0960-894X(01)80126-8 BindingDB Entry DOI: 10.7270/Q2862GCN
					More data for this Ligand-Target Pair