Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040747 ((3R,4R,7S,13S,16R)-16-Acetylamino-7-carboxymethyl-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040737 (CHEMBL165266 | [(7R,13R)-13-(3-Guanidino-propyl)-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040761 (CHEMBL164427 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040737 (CHEMBL165266 | [(7R,13R)-13-(3-Guanidino-propyl)-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]-SKF- 107260 binding to purified GPIIb/IIIa from human platelets reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040769 ((7S,13S,16R)-16-Amino-7-carboxymethyl-13-(3-guanid...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM31046 (3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem Similars | DrugBank PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from three separate experiments using 10 i... | J Med Chem 27: 918-21 (1984) BindingDB Entry DOI: 10.7270/Q2125VWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50225305 (CHEMBL433730) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from three separate experiments using 10 i... | J Med Chem 27: 918-21 (1984) BindingDB Entry DOI: 10.7270/Q2125VWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040755 ((7S,13S,16R)-16-Acetylamino-7-carboxymethyl-13-(3-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040752 (CHEMBL2371457 | [(7S,13S,16R)-16-Amino-4-carbamoyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040742 (CHEMBL165459 | [(11R,17R)-17-(3-Guanidino-propyl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040750 (CHEMBL2371446 | [(7S,13S,16R)-16-Benzoylamino-4-ca...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 13.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM66983 (6-chloranyl-3-methyl-1,2,4,5-tetrahydro-3-benzazep...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from three separate experiments using 10 i... | J Med Chem 27: 918-21 (1984) BindingDB Entry DOI: 10.7270/Q2125VWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040760 (CHEMBL355861 | [(4S,7R,13R,19S)-19-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040741 (CHEMBL349194 | [(7R,13S)-13-(3-Guanidino-propyl)-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040753 (CHEMBL2371459 | [(7S,13S,16R)-4-Carbamoyl-13-(3-gu...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 24.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040771 (CHEMBL165212 | [(12S,18S)-18-(3-Guanidino-propyl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 24.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040770 (CHEMBL351640 | [(8S,11R,17R)-8-Acetylamino-11-(3-g...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040735 (CHEMBL2371469 | [(7S,13S,16R)-4-Carbamoyl-13-(3-gu...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040756 (CHEMBL350724 | [(7R,13R)-13-(3-Guanidino-propyl)-6...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040767 (CHEMBL2371468 | [(7S,13S,16R)-4-Carbamoyl-13-(3-gu...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040765 (CHEMBL168140 | [(3S,4R,7S,13S,16R)-16-Acetylamino-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50225307 (CHEMBL170660) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from four to five separate experiments usi... | J Med Chem 27: 918-21 (1984) BindingDB Entry DOI: 10.7270/Q2125VWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040762 (CHEMBL2371456 | [(7S,13S,16R)-16-Acetylamino-4-car...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040762 (CHEMBL2371456 | [(7S,13S,16R)-16-Acetylamino-4-car...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]-SKF- 107260 binding to purified GPIIb/IIIa from human platelets reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040746 (CHEMBL262519 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040740 (CHEMBL349143 | [(4S,7R,13R,19S)-19-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 77 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040774 (CHEMBL349056 | [(4S,7R,13S,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040764 (CHEMBL351083 | [(4S,7R,13R,16R)-16-(Acetyl-methyl-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040763 (CHEMBL349052 | [(3R,4R,7S,13S,16R)-16-Acetylamino-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040773 (CHEMBL163965 | [(4S,7R,13R,19S)-19-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 135 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040775 (CHEMBL164670 | [(12S,18S)-18-(3-Guanidino-propyl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 143 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040757 (CHEMBL354319 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 188 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50225306 (CHEMBL355527) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 232 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in preparations in human platelet membranes from three separate experi... | J Med Chem 27: 918-21 (1984) BindingDB Entry DOI: 10.7270/Q2125VWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040758 (CHEMBL350185 | [(8S,11R,17R)-8-Acetylamino-11-(3-g...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50225308 (CHEMBL173581) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 338 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against alpha-2-adrenergic receptor using 10 nM [3H]yohimbine in human platelet membranes from three separate experiments using 10 i... | J Med Chem 27: 918-21 (1984) BindingDB Entry DOI: 10.7270/Q2125VWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040776 (CHEMBL167575 | [(4S,7R,13R,19S)-19-Acetylamino-17-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040754 (CHEMBL164818 | [(4S,7R,13R,19S)-19-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040759 (CHEMBL164514 | [(4S,7R,13S,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50010176 (CHEMBL107009 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040739 (CHEMBL165211 | Cyclo-S-S[Mba-P(Ne-Me)RGD-Man]) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040766 (CHEMBL353203 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040768 (CHEMBL351514 | [(4S,7R,13R,16R)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50421884 (CHEMBL2110309) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50010174 (3-[4-amino(imino)methylamino-1-methylcarboxamido-(...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040748 (CHEMBL438170 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040745 (CHEMBL164078 | [(7S,13R)-13-(3-Guanidino-propyl)-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040736 (CHEMBL424178 | [(5S,10S,13R,19R,21aS)-5-Acetylamin...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040743 (CHEMBL424017 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040749 (CHEMBL352467 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50040738 (CHEMBL165153 | [(4S,7R,13R,16S)-16-Acetylamino-14-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes | J Med Chem 37: 769-80 (1994) BindingDB Entry DOI: 10.7270/Q2445KJB | |||||||||||
More data for this Ligand-Target Pair |
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