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Compile Data Set for Download or QSAR

Found 171 hits with Last Name = 'shah' and Initial = 'np'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574085
PNG
(CHEMBL4863351)
Show SMILES CN(C)CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)C(N)=O
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n/an/a 2.40n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Nek2


(Homo sapiens (Human))
BDBM50574084
PNG
(CHEMBL4860697)
Show SMILES C[C@@H](Oc1cc(sc1C(N)=O)-c1cnc2cc(ccn12)-c1cnn(CCN(C)C)c1)c1ccccc1C(F)(F)F |r|
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n/an/a 3.20n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of NEK2 (unknown origin) using 5' FAM-KKLNRTLSVA-COOH peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574086
PNG
(CHEMBL4868026)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)C(N)=O
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n/an/a 9.70n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078775
PNG
(CHEMBL3416149)
Show SMILES Fc1ccc(cc1)-c1cnc2cc(ccn12)-c1cccs1
Show InChI InChI=1S/C17H11FN2S/c18-14-5-3-12(4-6-14)15-11-19-17-10-13(7-8-20(15)17)16-2-1-9-21-16/h1-11H
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n/an/a 15n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078840
PNG
(CHEMBL3416157)
Show SMILES Fc1ccc(cc1)-c1cnc2cc(ccn12)-c1ccccc1
Show InChI InChI=1S/C19H13FN2/c20-17-8-6-15(7-9-17)18-13-21-19-12-16(10-11-22(18)19)14-4-2-1-3-5-14/h1-13H
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n/an/a 16n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574084
PNG
(CHEMBL4860697)
Show SMILES C[C@@H](Oc1cc(sc1C(N)=O)-c1cnc2cc(ccn12)-c1cnn(CCN(C)C)c1)c1ccccc1C(F)(F)F |r|
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n/an/a 37n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50300690
PNG
(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(OCCN4CCOCC4)ccc32)no1
Show InChI InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)
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n/an/a 39n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078836
PNG
(CHEMBL3416153)
Show SMILES Fc1ccc(cc1)-c1cnc2cc(ccn12)-c1ccco1
Show InChI InChI=1S/C17H11FN2O/c18-14-5-3-12(4-6-14)15-11-19-17-10-13(7-8-20(15)17)16-2-1-9-21-16/h1-11H
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n/an/a 41n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078774
PNG
(CHEMBL3416147)
Show SMILES N#CCc1ccc(cc1)-c1cnc2cc(ccn12)-c1cccs1
Show InChI InChI=1S/C19H13N3S/c20-9-7-14-3-5-15(6-4-14)17-13-21-19-12-16(8-10-22(17)19)18-2-1-11-23-18/h1-6,8,10-13H,7H2
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n/an/a 51n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574091
PNG
(CHEMBL4847680)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1cccc(Cl)c1
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n/an/a 53n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM16673
PNG
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
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n/an/a 62n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078843
PNG
(CHEMBL3416161)
Show SMILES COc1ccc(cc1)-c1ccn2c(cnc2c1)-c1ccc(F)cc1
Show InChI InChI=1S/C20H15FN2O/c1-24-18-8-4-14(5-9-18)16-10-11-23-19(13-22-20(23)12-16)15-2-6-17(21)7-3-15/h2-13H,1H3
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n/an/a 78n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574087
PNG
(CHEMBL4868818)
Show SMILES Cn1cc(cn1)-c1ccc(s1)-c1cnc2cc(ccn12)-c1cnn(C)c1
PDB

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n/an/a 110n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574103
PNG
(CHEMBL4877108)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1ccoc1
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n/an/a 120n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574097
PNG
(CHEMBL4849272)
Show SMILES Cn1cc(cn1)-c1ccc(s1)-c1cnc2cc(ccn12)-c1ccc(cc1)S(C)(=O)=O
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n/an/a 120n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574089
PNG
(CHEMBL4876014)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1cccc(F)c1
PDB

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n/an/a 160n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078780
PNG
(CHEMBL3416152)
Show SMILES Cc1ccc(cc1)-c1cnc2cc(ccn12)-c1ccco1
Show InChI InChI=1S/C18H14N2O/c1-13-4-6-14(7-5-13)16-12-19-18-11-15(8-9-20(16)18)17-3-2-10-21-17/h2-12H,1H3
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n/an/a 160n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078777
PNG
(CHEMBL3416151)
Show SMILES N#CCc1ccc(cc1)-c1cnc2cc(ccn12)-c1ccco1
Show InChI InChI=1S/C19H13N3O/c20-9-7-14-3-5-15(6-4-14)17-13-21-19-12-16(8-10-22(17)19)18-2-1-11-23-18/h1-6,8,10-13H,7H2
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n/an/a 190n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574090
PNG
(CHEMBL4863689)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1ccc(Cl)cc1
PDB

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TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078837
PNG
(CHEMBL3416154)
Show SMILES Fc1ccc(cc1C#N)-c1cnc2cc(ccn12)-c1ccccc1
Show InChI InChI=1S/C20H12FN3/c21-18-7-6-16(10-17(18)12-22)19-13-23-20-11-15(8-9-24(19)20)14-4-2-1-3-5-14/h1-11,13H
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n/an/a 230n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574095
PNG
(CHEMBL4870662)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1cccnc1
PDB

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n/an/a 230n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574101
PNG
(CHEMBL4878572)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1cccnc1
PDB

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n/an/a 260n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574088
PNG
(CHEMBL4859133)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1ccc(F)cc1
PDB

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TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574098
PNG
(CHEMBL4872048)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1ccc(F)cc1
PDB

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n/an/a 270n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574102
PNG
(CHEMBL4867699)
Show SMILES CC(C)(C)c1ccc(cc1)-c1ccc(s1)-c1cnc2cc(ccn12)-c1ccc(cc1)S(C)(=O)=O
PDB

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TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078839
PNG
(CHEMBL3416156)
Show SMILES Cc1ccc(cc1)-c1cnc2cc(ccn12)-c1ccccc1
Show InChI InChI=1S/C20H16N2/c1-15-7-9-17(10-8-15)19-14-21-20-13-18(11-12-22(19)20)16-5-3-2-4-6-16/h2-14H,1H3
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n/an/a 300n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574096
PNG
(CHEMBL4860913)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1cccc(c1)C(F)(F)F
PDB

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n/an/a 300n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574093
PNG
(CHEMBL4852822)
Show SMILES COc1cccc(OC)c1-c1ccc(s1)-c1cnc2cc(ccn12)-c1cnn(C)c1
PDB

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n/an/a 310n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078841
PNG
(CHEMBL3416159)
Show SMILES COc1ccc(cc1)-c1ccn2c(cnc2c1)-c1ccc(CC#N)cc1
Show InChI InChI=1S/C22H17N3O/c1-26-20-8-6-17(7-9-20)19-11-13-25-21(15-24-22(25)14-19)18-4-2-16(3-5-18)10-12-23/h2-9,11,13-15H,10H2,1H3
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n/an/a 430n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078842
PNG
(CHEMBL3416160)
Show SMILES COc1ccc(cc1)-c1ccn2c(cnc2c1)-c1ccc(C)cc1
Show InChI InChI=1S/C21H18N2O/c1-15-3-5-17(6-4-15)20-14-22-21-13-18(11-12-23(20)21)16-7-9-19(24-2)10-8-16/h3-14H,1-2H3
PDB

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n/an/a 440n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574094
PNG
(CHEMBL4849959)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1ccncc1
PDB

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n/an/a 450n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078776
PNG
(CHEMBL3416150)
Show SMILES Fc1ccc(cc1C#N)-c1cnc2cc(ccn12)-c1ccco1
Show InChI InChI=1S/C18H10FN3O/c19-15-4-3-12(8-14(15)10-20)16-11-21-18-9-13(5-6-22(16)18)17-2-1-7-23-17/h1-9,11H
PDB

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n/an/a 470n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078773
PNG
(CHEMBL3416141)
Show SMILES Fc1ccc(cc1)-c1cnc2ccccn12
Show InChI InChI=1S/C13H9FN2/c14-11-6-4-10(5-7-11)12-9-15-13-3-1-2-8-16(12)13/h1-9H
PDB

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n/an/a 480n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574100
PNG
(CHEMBL4855716)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1ccncc1
PDB

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n/an/a 540n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574099
PNG
(CHEMBL4874305)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1ccccc1C(F)(F)F
PDB

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n/an/a 540n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50078838
PNG
(CHEMBL3416155)
Show SMILES N#CCc1ccc(cc1)-c1cnc2cc(ccn12)-c1ccccc1
Show InChI InChI=1S/C21H15N3/c22-12-10-16-6-8-18(9-7-16)20-15-23-21-14-19(11-13-24(20)21)17-4-2-1-3-5-17/h1-9,11,13-15H,10H2
PDB

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n/an/a 550n/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...


Eur J Med Chem 94: 123-31 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.052
BindingDB Entry DOI: 10.7270/Q2Z039VC
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574107
PNG
(CHEMBL4857928)
Show SMILES Cn1cc(cn1)-c1ccc2ncc(-c3ccc(s3)-c3ccoc3)n2c1
PDB

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n/an/a 580n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574092
PNG
(CHEMBL4848966)
Show SMILES COc1cc(ccc1-c1ccc(s1)-c1cnc2cc(ccn12)-c1cnn(C)c1)C(F)(F)F
PDB

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n/an/a 760n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Aurora kinase A


(Homo sapiens (Human))
BDBM50574093
PNG
(CHEMBL4852822)
Show SMILES COc1cccc(OC)c1-c1ccc(s1)-c1cnc2cc(ccn12)-c1cnn(C)c1
PDB
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n/an/a 970n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Aurora A (unknown origin) using 5' FAM-LRRASLG-CONH2 peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574104
PNG
(CHEMBL4878277)
Show SMILES Cn1cc(cn1)-c1ccc(s1)-c1cnc2ccc(cn12)-c1cnn(C)c1
PDB

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n/an/a 1.21E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Aurora kinase A


(Homo sapiens (Human))
BDBM50574091
PNG
(CHEMBL4847680)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1cccc(Cl)c1
PDB
MMDB

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n/an/a 1.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Aurora A (unknown origin) using 5' FAM-LRRASLG-CONH2 peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Nek2


(Homo sapiens (Human))
BDBM50574085
PNG
(CHEMBL4863351)
Show SMILES CN(C)CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)C(N)=O
PDB

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n/an/a 1.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of NEK2 (unknown origin) using 5' FAM-KKLNRTLSVA-COOH peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574106
PNG
(CHEMBL4873041)
Show SMILES Cn1cc(cn1)-c1ccc2ncc(-c3ccc(s3)-c3ccc(Cl)cc3)n2c1
PDB

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n/an/a 1.64E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574105
PNG
(CHEMBL4863364)
Show SMILES Cn1cc(cn1)-c1ccc2ncc(-c3ccc(s3)-c3ccc(F)cc3)n2c1
PDB

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n/an/a 1.91E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574110
PNG
(CHEMBL4859180)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2ncc(-c3ccc(s3)-c3cccc(Cl)c3)n2c1
PDB

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n/an/a 2.08E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Nek2


(Homo sapiens (Human))
BDBM50574086
PNG
(CHEMBL4868026)
Show SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)C(N)=O
PDB

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n/an/a 2.35E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of NEK2 (unknown origin) using 5' FAM-KKLNRTLSVA-COOH peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50574093
PNG
(CHEMBL4852822)
Show SMILES COc1cccc(OC)c1-c1ccc(s1)-c1cnc2cc(ccn12)-c1cnn(C)c1
PDB

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n/an/a 2.84E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CSF-1R (unknown origin) using 5' FAM-KKKKEEIYFFF-CONH2 peptide as a substrate in the presence of ATP incubated for 60 mins by microflui...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574108
PNG
(CHEMBL4879086)
Show SMILES Cn1cc(cn1)-c1ccc(s1)-c1cnc2ccc(cn12)-c1ccc(cc1)S(C)(=O)=O
PDB

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n/an/a 2.91E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574112
PNG
(CHEMBL4846528)
Show SMILES Cn1cc(cn1)-c1ccc(s1)-c1cnc2ccccn12
PDB

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UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.35E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50574109
PNG
(CHEMBL4869856)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2ncc(-c3ccc(s3)-c3ccc(F)cc3)n2c1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.72E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assay


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113776
BindingDB Entry DOI: 10.7270/Q2NZ8CFK
More data for this
Ligand-Target Pair
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