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Compile Data Set for Download or QSAR

Found 25 hits with Last Name = 'shang' and Initial = 'ff'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576956
PNG
(CHEMBL4849804)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCCOc1cnc2ccccc2c1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576962
PNG
(CHEMBL4849133)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)Nc1cc(C)on1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576965
PNG
(CHEMBL4852306)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCCOc1ccc2ccc(=O)oc2c1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576951
PNG
(CHEMBL4860987)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)Nc1cnc2ccccc2c1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576950
PNG
(CHEMBL4861387)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)NCc1cn(nn1)-c1ccc(Cl)c(Cl)c1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576964
PNG
(CHEMBL4848196)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCCOc1cc(=O)oc2ccccc12 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576963
PNG
(CHEMBL4854524)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCCOc1cc(C)oc(=O)c1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576945
PNG
(CHEMBL4854660)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)NC(c1ccc(OC)cc1)P(=O)(OCC)OCC |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576961
PNG
(CHEMBL4875514)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)Nc1ccc(F)nc1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576958
PNG
(CHEMBL4856721)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCCOc1ccc2cccnc2c1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576942
PNG
(CHEMBL4855426)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)NC(c1ccccc1)P(=O)(OCC)OCC |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576954
PNG
(CHEMBL4857949)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)Nc1ccc2ncccc2c1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50071058
PNG
((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Show SMILES C[C@]12CC[C@](C)(C[C@H]1[C@]1(C)CC[C@]3(C)C(=CC=c4c3cc(O)c(O)c4=C)[C@@]1(C)CC2)C(O)=O |r,c:15,17|
Show InChI InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,30-31H,1,9-14,16H2,2-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
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n/an/a 250n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576960
PNG
(CHEMBL4853725)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)Nc1ccc(F)cn1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576955
PNG
(CHEMBL4866598)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)Nc1cccc2cccnc12 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576953
PNG
(CHEMBL4878396)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)Nc1cccc2ncccc12 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576952
PNG
(CHEMBL4858190)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)Nc1ccnc2ccccc12 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576946
PNG
(CHEMBL4875459)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)NCc1cn(nn1)-c1ccccc1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576947
PNG
(CHEMBL4858245)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)NCc1cn(nn1)-c1ccc(C)cc1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576949
PNG
(CHEMBL4859671)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)NCc1cn(nn1)-c1ccc(Cl)cc1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576957
PNG
(CHEMBL4850627)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCCOc1cccc2ncccc12 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576948
PNG
(CHEMBL4850587)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)NCc1cn(nn1)-c1ccc(OC)cc1 |r,c:24,t:14,16,19|
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TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576944
PNG
(CHEMBL4848625)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)NC(c1ccc(C)cc1)P(=O)(OCC)OCC |r,c:24,t:14,16,19|
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PC sid
UniChem
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n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576943
PNG
(CHEMBL4873071)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)NC(c1ccc(F)cc1)P(=O)(OCC)OCC |r,c:24,t:14,16,19|
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PC cid
PC sid
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Article
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n/an/a>3.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))
BDBM50576959
PNG
(CHEMBL4872939)
Show SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC(=O)Nc1ccncc1 |r,c:24,t:14,16,19|
PDB

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KEGG

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.20E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells co-transfected with luciferase reporter plasmid containing six ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113474
BindingDB Entry DOI: 10.7270/Q2WQ07MW
More data for this
Ligand-Target Pair