Found 70 hits with Last Name = 'shook' and Initial = 'je' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020202
(CHEMBL2369466 | D-Tic-c(Cys-Tyr-D-Trp-Lys-Thr-Pen-...)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H]1Cc2ccccc2CN1)[C@@H](C)O Show InChI InChI=1S/C52H69N11O11S2/c1-27(64)41(44(54)67)61-51(74)43-52(3,4)76-75-26-40(60-46(69)37-22-30-11-5-6-12-31(30)24-56-37)49(72)58-38(21-29-16-18-33(66)19-17-29)47(70)59-39(23-32-25-55-35-14-8-7-13-34(32)35)48(71)57-36(15-9-10-20-53)45(68)62-42(28(2)65)50(73)63-43/h5-8,11-14,16-19,25,27-28,36-43,55-56,64-66H,9-10,15,20-24,26,53H2,1-4H3,(H2,54,67)(H,57,71)(H,58,72)(H,59,70)(H,60,69)(H,61,74)(H,62,68)(H,63,73)/t27-,28-,36+,37-,38-,39+,40+,41+,42+,43-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020202
(CHEMBL2369466 | D-Tic-c(Cys-Tyr-D-Trp-Lys-Thr-Pen-...)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H]1Cc2ccccc2CN1)[C@@H](C)O Show InChI InChI=1S/C52H69N11O11S2/c1-27(64)41(44(54)67)61-51(74)43-52(3,4)76-75-26-40(60-46(69)37-22-30-11-5-6-12-31(30)24-56-37)49(72)58-38(21-29-16-18-33(66)19-17-29)47(70)59-39(23-32-25-55-35-14-8-7-13-34(32)35)48(71)57-36(15-9-10-20-53)45(68)62-42(28(2)65)50(73)63-43/h5-8,11-14,16-19,25,27-28,36-43,55-56,64-66H,9-10,15,20-24,26,53H2,1-4H3,(H2,54,67)(H,57,71)(H,58,72)(H,59,70)(H,60,69)(H,61,74)(H,62,68)(H,63,73)/t27-,28-,36+,37-,38-,39+,40+,41+,42+,43-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020208
(CHEMBL1795717 | TCTAP)Show SMILES [H][C@](NC(=O)[C@@]1([H])NC(=O)[C@@]([H])(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@]([H])(CSSC1(C)C)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)([C@@H](C)O)C(N)=O |r| Show InChI InChI=1S/C51H69N13O11S2/c1-26(65)39(42(53)68)62-49(75)41-51(3,4)77-76-25-38(61-43(69)33(52)21-28-11-6-5-7-12-28)47(73)59-36(22-29-16-18-31(67)19-17-29)45(71)60-37(23-30-24-57-34-14-9-8-13-32(30)34)46(72)58-35(15-10-20-56-50(54)55)44(70)63-40(27(2)66)48(74)64-41/h5-9,11-14,16-19,24,26-27,33,35-41,57,65-67H,10,15,20-23,25,52H2,1-4H3,(H2,53,68)(H,58,72)(H,59,73)(H,60,71)(H,61,69)(H,62,75)(H,63,70)(H,64,74)(H4,54,55,56)/t26-,27-,33-,35+,36+,37-,38+,39+,40+,41-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020208
(CHEMBL1795717 | TCTAP)Show SMILES [H][C@](NC(=O)[C@@]1([H])NC(=O)[C@@]([H])(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@]([H])(CSSC1(C)C)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)([C@@H](C)O)C(N)=O |r| Show InChI InChI=1S/C51H69N13O11S2/c1-26(65)39(42(53)68)62-49(75)41-51(3,4)77-76-25-38(61-43(69)33(52)21-28-11-6-5-7-12-28)47(73)59-36(22-29-16-18-31(67)19-17-29)45(71)60-37(23-30-24-57-34-14-9-8-13-32(30)34)46(72)58-35(15-10-20-56-50(54)55)44(70)63-40(27(2)66)48(74)64-41/h5-9,11-14,16-19,24,26-27,33,35-41,57,65-67H,10,15,20-23,25,52H2,1-4H3,(H2,53,68)(H,58,72)(H,59,73)(H,60,71)(H,61,69)(H,62,75)(H,63,70)(H,64,74)(H4,54,55,56)/t26-,27-,33-,35+,36+,37-,38+,39+,40+,41-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50001683
(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)Show SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding potency of compound in competition with [3H]DPDPE for Opioid receptor delta 1 tested in rat brain membrane |
J Med Chem 32: 638-43 (1989)
BindingDB Entry DOI: 10.7270/Q2DN45N0 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020209
(CHEMBL410090 | CTP)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C51H69N11O11S2/c1-27(63)40(43(54)66)60-50(73)42-51(3,4)75-74-26-39(59-44(67)34(53)22-29-12-6-5-7-13-29)48(71)57-37(23-30-17-19-32(65)20-18-30)46(69)58-38(24-31-25-55-35-15-9-8-14-33(31)35)47(70)56-36(16-10-11-21-52)45(68)61-41(28(2)64)49(72)62-42/h5-9,12-15,17-20,25,27-28,34,36-42,55,63-65H,10-11,16,21-24,26,52-53H2,1-4H3,(H2,54,66)(H,56,70)(H,57,71)(H,58,69)(H,59,67)(H,60,73)(H,61,68)(H,62,72)/t27-,28-,34+,36+,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020206
(CHEMBL266829 | CTOP)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C45H69N11O11S2/c1-24(57)34(37(49)60)54-44(67)36-45(3,4)69-68-23-33(53-38(61)29(48)21-26-11-6-5-7-12-26)42(65)52-32(22-27-15-17-28(59)18-16-27)41(64)51-31(14-10-20-47)39(62)50-30(13-8-9-19-46)40(63)55-35(25(2)58)43(66)56-36/h5-7,11-12,15-18,24-25,29-36,57-59H,8-10,13-14,19-23,46-48H2,1-4H3,(H2,49,60)(H,50,62)(H,51,64)(H,52,65)(H,53,61)(H,54,67)(H,55,63)(H,56,66)/t24-,25-,29+,30+,31+,32+,33+,34+,35+,36-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020213
(CHEMBL264082 | D-Trpc(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C53H70N12O11S2/c1-27(66)42(45(56)69)63-52(76)44-53(3,4)78-77-26-41(62-46(70)35(55)22-30-24-57-36-13-7-5-11-33(30)36)50(74)60-39(21-29-16-18-32(68)19-17-29)48(72)61-40(23-31-25-58-37-14-8-6-12-34(31)37)49(73)59-38(15-9-10-20-54)47(71)64-43(28(2)67)51(75)65-44/h5-8,11-14,16-19,24-25,27-28,35,38-44,57-58,66-68H,9-10,15,20-23,26,54-55H2,1-4H3,(H2,56,69)(H,59,73)(H,60,74)(H,61,72)(H,62,70)(H,63,76)(H,64,71)(H,65,75)/t27-,28-,35+,38+,39+,40+,41+,42+,43+,44-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020205
(CHEMBL216354 | D-Tic-c(Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C51H67N11O11S2/c1-27(64)41-49(72)62-42(50(73)59-39(25-63)43(53)66)51(2,3)75-74-26-40(60-45(68)36-21-29-10-4-5-11-30(29)23-55-36)48(71)57-37(20-28-15-17-32(65)18-16-28)46(69)58-38(22-31-24-54-34-13-7-6-12-33(31)34)47(70)56-35(44(67)61-41)14-8-9-19-52/h4-7,10-13,15-18,24,27,35-42,54-55,63-65H,8-9,14,19-23,25-26,52H2,1-3H3,(H2,53,66)(H,56,70)(H,57,71)(H,58,69)(H,59,73)(H,60,68)(H,61,67)(H,62,72)/t27-,35+,36-,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020216
(CHEMBL413831 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen)-...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C50H67N11O11S2/c1-27(63)40-48(71)61-41(49(72)58-38(25-62)42(53)65)50(2,3)74-73-26-39(59-43(66)33(52)21-28-11-5-4-6-12-28)47(70)56-36(22-29-16-18-31(64)19-17-29)45(68)57-37(23-30-24-54-34-14-8-7-13-32(30)34)46(69)55-35(44(67)60-40)15-9-10-20-51/h4-8,11-14,16-19,24,27,33,35-41,54,62-64H,9-10,15,20-23,25-26,51-52H2,1-3H3,(H2,53,65)(H,55,69)(H,56,70)(H,57,68)(H,58,72)(H,59,66)(H,60,67)(H,61,71)/t27-,33-,35+,36+,37+,38+,39+,40+,41-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020200
(CHEMBL405672 | D-Ticc(-Cys-Tyr-D-Typ-Lys-Thr-Pen-)...)Show SMILES CC(C)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C53H71N11O10S2/c1-28(2)42(45(55)67)62-52(74)44-53(4,5)76-75-27-41(61-47(69)38-23-31-12-6-7-13-32(31)25-57-38)50(72)59-39(22-30-17-19-34(66)20-18-30)48(70)60-40(24-33-26-56-36-15-9-8-14-35(33)36)49(71)58-37(16-10-11-21-54)46(68)63-43(29(3)65)51(73)64-44/h6-9,12-15,17-20,26,28-29,37-44,56-57,65-66H,10-11,16,21-25,27,54H2,1-5H3,(H2,55,67)(H,58,71)(H,59,72)(H,60,70)(H,61,69)(H,62,74)(H,63,68)(H,64,73)/t29-,37+,38-,39+,40+,41+,42+,43+,44-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020198
(CHEMBL308471 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C47H62N10O9S2/c1-26(58)38-46(66)57-39(40(50)60)47(2,3)68-67-25-37(55-41(61)32(49)21-27-11-5-4-6-12-27)45(65)53-35(22-28-16-18-30(59)19-17-28)43(63)54-36(23-29-24-51-33-14-8-7-13-31(29)33)44(64)52-34(42(62)56-38)15-9-10-20-48/h4-8,11-14,16-19,24,26,32,34-39,51,58-59H,9-10,15,20-23,25,48-49H2,1-3H3,(H2,50,60)(H,52,64)(H,53,65)(H,54,63)(H,55,61)(H,56,62)(H,57,66)/t26-,32-,34+,35+,36+,37+,38+,39-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 115 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020211
(CHEMBL216353 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C51H68N12O11S2/c1-27(64)41-49(73)63-42(50(74)58-36(43(55)67)24-40(54)66)51(2,3)76-75-26-39(61-44(68)33(53)21-28-11-5-4-6-12-28)48(72)59-37(22-29-16-18-31(65)19-17-29)46(70)60-38(23-30-25-56-34-14-8-7-13-32(30)34)47(71)57-35(45(69)62-41)15-9-10-20-52/h4-8,11-14,16-19,25,27,33,35-39,41-42,56,64-65H,9-10,15,20-24,26,52-53H2,1-3H3,(H2,54,66)(H2,55,67)(H,57,71)(H,58,74)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,63,73)/t27-,33-,35+,36+,37+,38+,39+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020215
(CHEMBL541457 | D-Phec(-Cys-Tyr-D-Trp-Orn-The-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C46H60N10O9S2/c1-25(57)37-45(65)56-38(39(49)59)46(2,3)67-66-24-36(54-40(60)31(48)20-26-10-5-4-6-11-26)44(64)52-34(21-27-15-17-29(58)18-16-27)42(62)53-35(22-28-23-50-32-13-8-7-12-30(28)32)43(63)51-33(14-9-19-47)41(61)55-37/h4-8,10-13,15-18,23,25,31,33-38,50,57-58H,9,14,19-22,24,47-48H2,1-3H3,(H2,49,59)(H,51,63)(H,52,64)(H,53,62)(H,54,60)(H,55,61)(H,56,65)/t25-,31-,33+,34+,35+,36+,37+,38-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 187 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020207
(CHEMBL2369473 | Gly-D-Ticc(-Cys-Tyr-D-Trp-Orn-Thr-...)Show SMILES [H][C@]1(NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)CN)[C@@H](C)O Show InChI InChI=1S/C53H70N12O12S2/c1-27(66)42(45(56)70)62-52(77)44-53(3,4)79-78-26-39(61-50(75)40-22-30-10-5-6-11-31(30)25-65(40)41(69)23-55)49(74)59-37(20-29-15-17-33(68)18-16-29)47(72)60-38(21-32-24-57-35-13-8-7-12-34(32)35)48(73)58-36(14-9-19-54)46(71)63-43(28(2)67)51(76)64-44/h5-8,10-13,15-18,24,27-28,36-40,42-44,57,66-68H,9,14,19-23,25-26,54-55H2,1-4H3,(H2,56,70)(H,58,73)(H,59,74)(H,60,72)(H,61,75)(H,62,77)(H,63,71)(H,64,76)/t27-,28-,36+,37-,38+,39+,40-,42+,43+,44-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 278 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020207
(CHEMBL2369473 | Gly-D-Ticc(-Cys-Tyr-D-Trp-Orn-Thr-...)Show SMILES [H][C@]1(NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)CN)[C@@H](C)O Show InChI InChI=1S/C53H70N12O12S2/c1-27(66)42(45(56)70)62-52(77)44-53(3,4)79-78-26-39(61-50(75)40-22-30-10-5-6-11-31(30)25-65(40)41(69)23-55)49(74)59-37(20-29-15-17-33(68)18-16-29)47(72)60-38(21-32-24-57-35-13-8-7-12-34(32)35)48(73)58-36(14-9-19-54)46(71)63-43(28(2)67)51(76)64-44/h5-8,10-13,15-18,24,27-28,36-40,42-44,57,66-68H,9,14,19-23,25-26,54-55H2,1-4H3,(H2,56,70)(H,58,73)(H,59,74)(H,60,72)(H,61,75)(H,62,77)(H,63,71)(H,64,76)/t27-,28-,36+,37-,38+,39+,40-,42+,43+,44-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 278 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020199
(CHEMBL441164 | D-N-Me-Phec(-Cys-Tyr-D-Trp-Orn-Thr-...)Show SMILES CN[C@H](Cc1ccccc1)C(=O)N[C@H]1CSSC(C)(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O Show InChI InChI=1S/C51H69N11O11S2/c1-27(63)40(43(53)66)60-50(73)42-51(3,4)75-74-26-39(59-45(68)36(54-5)22-29-12-7-6-8-13-29)48(71)57-37(23-30-17-19-32(65)20-18-30)46(69)58-38(24-31-25-55-34-15-10-9-14-33(31)34)47(70)56-35(16-11-21-52)44(67)61-41(28(2)64)49(72)62-42/h6-10,12-15,17-20,25,27-28,35-42,54-55,63-65H,11,16,21-24,26,52H2,1-5H3,(H2,53,66)(H,56,70)(H,57,71)(H,58,69)(H,59,68)(H,60,73)(H,61,67)(H,62,72)/t27-,28-,35+,36-,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 284 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50001683
(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)Show SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 385 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
The ability to displace [3H]naloxone from the Opioid receptor mu 1 isolated from rat brain membrane. |
J Med Chem 32: 638-43 (1989)
BindingDB Entry DOI: 10.7270/Q2DN45N0 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50452603
(CHEMBL2371213)Show SMILES [H][C@]1(NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(N)cc2)NC(=O)[C@@H](CSSC(C)(C)[C@@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O Show InChI InChI=1S/C51H70N12O10S2/c1-27(64)40(43(55)66)61-50(73)42-51(3,4)75-74-26-39(60-44(67)34(54)22-29-12-6-5-7-13-29)48(71)58-37(23-30-17-19-32(53)20-18-30)46(69)59-38(24-31-25-56-35-15-9-8-14-33(31)35)47(70)57-36(16-10-11-21-52)45(68)62-41(28(2)65)49(72)63-42/h5-9,12-15,17-20,25,27-28,34,36-42,56,64-65H,10-11,16,21-24,26,52-54H2,1-4H3,(H2,55,66)(H,57,70)(H,58,71)(H,59,69)(H,60,67)(H,61,73)(H,62,68)(H,63,72)/t27-,28-,34+,36-,37-,38-,39-,40+,41+,42+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding potency of compound in competition with [3H]CTOP for Opioid receptor mu 1 tested in rat brain membrane |
J Med Chem 32: 638-43 (1989)
BindingDB Entry DOI: 10.7270/Q2DN45N0 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020202
(CHEMBL2369466 | D-Tic-c(Cys-Tyr-D-Trp-Lys-Thr-Pen-...)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H]1Cc2ccccc2CN1)[C@@H](C)O Show InChI InChI=1S/C52H69N11O11S2/c1-27(64)41(44(54)67)61-51(74)43-52(3,4)76-75-26-40(60-46(69)37-22-30-11-5-6-12-31(30)24-56-37)49(72)58-38(21-29-16-18-33(66)19-17-29)47(70)59-39(23-32-25-55-35-14-8-7-13-34(32)35)48(71)57-36(15-9-10-20-53)45(68)62-42(28(2)65)50(73)63-43/h5-8,11-14,16-19,25,27-28,36-43,55-56,64-66H,9-10,15,20-24,26,53H2,1-4H3,(H2,54,67)(H,57,71)(H,58,72)(H,59,70)(H,60,69)(H,61,74)(H,62,68)(H,63,73)/t27-,28-,36+,37-,38-,39+,40+,41+,42+,43-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 949 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50016857
(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)Show SMILES CC1(C)SSC(C)(C)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccc(N)cc2)C(=O)N[C@H]1C(O)=O Show InChI InChI=1S/C30H40N6O7S2/c1-29(2)23(35-25(39)20(32)13-16-7-11-19(37)12-8-16)27(41)33-15-22(38)34-21(14-17-5-9-18(31)10-6-17)26(40)36-24(28(42)43)30(3,4)45-44-29/h5-12,20-21,23-24,37H,13-15,31-32H2,1-4H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40)(H,42,43)/t20-,21-,23+,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding potency of compound in competition with [3H]CTOP for Opioid receptor mu 1 tested in rat brain membrane |
J Med Chem 32: 638-43 (1989)
BindingDB Entry DOI: 10.7270/Q2DN45N0 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50016857
(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)Show SMILES CC1(C)SSC(C)(C)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccc(N)cc2)C(=O)N[C@H]1C(O)=O Show InChI InChI=1S/C30H40N6O7S2/c1-29(2)23(35-25(39)20(32)13-16-7-11-19(37)12-8-16)27(41)33-15-22(38)34-21(14-17-5-9-18(31)10-6-17)26(40)36-24(28(42)43)30(3,4)45-44-29/h5-12,20-21,23-24,37H,13-15,31-32H2,1-4H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40)(H,42,43)/t20-,21-,23+,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding potency of compound in competition with [3H]DPDPE for Opioid receptor delta 1 tested in rat brain membrane |
J Med Chem 32: 638-43 (1989)
BindingDB Entry DOI: 10.7270/Q2DN45N0 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020209
(CHEMBL410090 | CTP)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C51H69N11O11S2/c1-27(63)40(43(54)66)60-50(73)42-51(3,4)75-74-26-39(59-44(67)34(53)22-29-12-6-5-7-13-29)48(71)57-37(23-30-17-19-32(65)20-18-30)46(69)58-38(24-31-25-55-35-15-9-8-14-33(31)35)47(70)56-36(16-10-11-21-52)45(68)61-41(28(2)64)49(72)62-42/h5-9,12-15,17-20,25,27-28,34,36-42,55,63-65H,10-11,16,21-24,26,52-53H2,1-4H3,(H2,54,66)(H,56,70)(H,57,71)(H,58,69)(H,59,67)(H,60,73)(H,61,68)(H,62,72)/t27-,28-,34+,36+,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020203
(CHEMBL2369474 | D-Ticc(-Cys-Tyr-D-Trp-Lys-Pen-)Thr...)Show SMILES [H][C@]1(NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@@H]1Cc2ccccc2CN1)[C@@H](C)O |wU:66.69,16.16,30.32,57.62,5.5,wD:49.56,56.59,42.66,76.83,1.0,(-3.25,5.4,;-1.52,4.68,;-2.9,3.98,;-3.98,2.9,;-4.98,3.62,;-4.69,1.52,;-6.16,2.01,;-6.47,3.51,;-7.94,3.99,;-8.26,5.5,;-9.72,5.98,;-9.98,7.18,;-10.64,5.15,;-4.93,,;-4.69,-1.52,;-5.86,-1.9,;-3.98,-2.89,;-5.24,-3.8,;-6.65,-3.17,;-6.95,-1.67,;-8.45,-1.51,;-9.09,-2.91,;-10.57,-3.36,;-10.9,-4.88,;-9.77,-5.92,;-8.27,-5.46,;-7.96,-3.95,;-2.9,-3.98,;-1.52,-4.68,;-1.9,-5.85,;,-4.92,;-0,-6.47,;-1.34,-7.24,;-1.35,-8.78,;-2.68,-9.55,;-4.01,-8.77,;-5.08,-9.39,;-4.01,-7.23,;-2.67,-6.47,;1.52,-4.68,;2.89,-3.98,;3.62,-4.98,;3.98,-2.89,;4.68,-1.52,;4.92,,;4.68,1.52,;3.98,2.9,;3.78,4.11,;5.08,2.33,;2.89,3.98,;1.52,4.68,;,4.92,;,6.15,;3.8,5.24,;5.03,5.11,;3.17,6.65,;4.08,7.9,;5.61,7.73,;6.33,8.73,;6.11,6.61,;3.45,9.3,;2.22,9.43,;4.17,10.3,;5.23,-3.81,;5.07,-5.34,;3.95,-5.84,;6.32,-6.25,;6.16,-7.79,;7.4,-8.7,;7.24,-10.23,;8.49,-11.13,;9.89,-10.51,;10.05,-8.98,;8.81,-8.08,;8.97,-6.54,;7.72,-5.62,;-2,6.16,;-1.18,7.07,;-3.21,6.41,)| Show InChI InChI=1S/C52H69N13O11S2/c1-26(66)40(43(53)69)63-50(76)42-52(3,4)78-77-25-39(62-45(71)36-21-29-10-5-6-11-30(29)23-58-36)48(74)60-37(20-28-15-17-32(68)18-16-28)46(72)61-38(22-31-24-57-34-13-8-7-12-33(31)34)47(73)59-35(14-9-19-56-51(54)55)44(70)64-41(27(2)67)49(75)65-42/h5-8,10-13,15-18,24,26-27,35-42,57-58,66-68H,9,14,19-23,25H2,1-4H3,(H2,53,69)(H,59,73)(H,60,74)(H,61,72)(H,62,71)(H,63,76)(H,64,70)(H,65,75)(H4,54,55,56)/t26-,27-,35+,36+,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020203
(CHEMBL2369474 | D-Ticc(-Cys-Tyr-D-Trp-Lys-Pen-)Thr...)Show SMILES [H][C@]1(NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@@H]1Cc2ccccc2CN1)[C@@H](C)O |wU:66.69,16.16,30.32,57.62,5.5,wD:49.56,56.59,42.66,76.83,1.0,(-3.25,5.4,;-1.52,4.68,;-2.9,3.98,;-3.98,2.9,;-4.98,3.62,;-4.69,1.52,;-6.16,2.01,;-6.47,3.51,;-7.94,3.99,;-8.26,5.5,;-9.72,5.98,;-9.98,7.18,;-10.64,5.15,;-4.93,,;-4.69,-1.52,;-5.86,-1.9,;-3.98,-2.89,;-5.24,-3.8,;-6.65,-3.17,;-6.95,-1.67,;-8.45,-1.51,;-9.09,-2.91,;-10.57,-3.36,;-10.9,-4.88,;-9.77,-5.92,;-8.27,-5.46,;-7.96,-3.95,;-2.9,-3.98,;-1.52,-4.68,;-1.9,-5.85,;,-4.92,;-0,-6.47,;-1.34,-7.24,;-1.35,-8.78,;-2.68,-9.55,;-4.01,-8.77,;-5.08,-9.39,;-4.01,-7.23,;-2.67,-6.47,;1.52,-4.68,;2.89,-3.98,;3.62,-4.98,;3.98,-2.89,;4.68,-1.52,;4.92,,;4.68,1.52,;3.98,2.9,;3.78,4.11,;5.08,2.33,;2.89,3.98,;1.52,4.68,;,4.92,;,6.15,;3.8,5.24,;5.03,5.11,;3.17,6.65,;4.08,7.9,;5.61,7.73,;6.33,8.73,;6.11,6.61,;3.45,9.3,;2.22,9.43,;4.17,10.3,;5.23,-3.81,;5.07,-5.34,;3.95,-5.84,;6.32,-6.25,;6.16,-7.79,;7.4,-8.7,;7.24,-10.23,;8.49,-11.13,;9.89,-10.51,;10.05,-8.98,;8.81,-8.08,;8.97,-6.54,;7.72,-5.62,;-2,6.16,;-1.18,7.07,;-3.21,6.41,)| Show InChI InChI=1S/C52H69N13O11S2/c1-26(66)40(43(53)69)63-50(76)42-52(3,4)78-77-25-39(62-45(71)36-21-29-10-5-6-11-30(29)23-58-36)48(74)60-37(20-28-15-17-32(68)18-16-28)46(72)61-38(22-31-24-57-34-13-8-7-12-33(31)34)47(73)59-35(14-9-19-56-51(54)55)44(70)64-41(27(2)67)49(75)65-42/h5-8,10-13,15-18,24,26-27,35-42,57-58,66-68H,9,14,19-23,25H2,1-4H3,(H2,53,69)(H,59,73)(H,60,74)(H,61,72)(H,62,71)(H,63,76)(H,64,70)(H,65,75)(H4,54,55,56)/t26-,27-,35+,36+,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020209
(CHEMBL410090 | CTP)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C51H69N11O11S2/c1-27(63)40(43(54)66)60-50(73)42-51(3,4)75-74-26-39(59-44(67)34(53)22-29-12-6-5-7-13-29)48(71)57-37(23-30-17-19-32(65)20-18-30)46(69)58-38(24-31-25-55-35-15-9-8-14-33(31)35)47(70)56-36(16-10-11-21-52)45(68)61-41(28(2)64)49(72)62-42/h5-9,12-15,17-20,25,27-28,34,36-42,55,63-65H,10-11,16,21-24,26,52-53H2,1-4H3,(H2,54,66)(H,56,70)(H,57,71)(H,58,69)(H,59,67)(H,60,73)(H,61,68)(H,62,72)/t27-,28-,34+,36+,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020205
(CHEMBL216354 | D-Tic-c(Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C51H67N11O11S2/c1-27(64)41-49(72)62-42(50(73)59-39(25-63)43(53)66)51(2,3)75-74-26-40(60-45(68)36-21-29-10-4-5-11-30(29)23-55-36)48(71)57-37(20-28-15-17-32(65)18-16-28)46(69)58-38(22-31-24-54-34-13-7-6-12-33(31)34)47(70)56-35(44(67)61-41)14-8-9-19-52/h4-7,10-13,15-18,24,27,35-42,54-55,63-65H,8-9,14,19-23,25-26,52H2,1-3H3,(H2,53,66)(H,56,70)(H,57,71)(H,58,69)(H,59,73)(H,60,68)(H,61,67)(H,62,72)/t27-,35+,36-,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020213
(CHEMBL264082 | D-Trpc(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C53H70N12O11S2/c1-27(66)42(45(56)69)63-52(76)44-53(3,4)78-77-26-41(62-46(70)35(55)22-30-24-57-36-13-7-5-11-33(30)36)50(74)60-39(21-29-16-18-32(68)19-17-29)48(72)61-40(23-31-25-58-37-14-8-6-12-34(31)37)49(73)59-38(15-9-10-20-54)47(71)64-43(28(2)67)51(75)65-44/h5-8,11-14,16-19,24-25,27-28,35,38-44,57-58,66-68H,9-10,15,20-23,26,54-55H2,1-4H3,(H2,56,69)(H,59,73)(H,60,74)(H,61,72)(H,62,70)(H,63,76)(H,64,71)(H,65,75)/t27-,28-,35+,38+,39+,40+,41+,42+,43+,44-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020211
(CHEMBL216353 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C51H68N12O11S2/c1-27(64)41-49(73)63-42(50(74)58-36(43(55)67)24-40(54)66)51(2,3)76-75-26-39(61-44(68)33(53)21-28-11-5-4-6-12-28)48(72)59-37(22-29-16-18-31(65)19-17-29)46(70)60-38(23-30-25-56-34-14-8-7-13-32(30)34)47(71)57-35(45(69)62-41)15-9-10-20-52/h4-8,11-14,16-19,25,27,33,35-39,41-42,56,64-65H,9-10,15,20-24,26,52-53H2,1-3H3,(H2,54,66)(H2,55,67)(H,57,71)(H,58,74)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,63,73)/t27-,33-,35+,36+,37+,38+,39+,41+,42-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020216
(CHEMBL413831 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen)-...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C50H67N11O11S2/c1-27(63)40-48(71)61-41(49(72)58-38(25-62)42(53)65)50(2,3)74-73-26-39(59-43(66)33(52)21-28-11-5-4-6-12-28)47(70)56-36(22-29-16-18-31(64)19-17-29)45(68)57-37(23-30-24-54-34-14-8-7-13-32(30)34)46(69)55-35(44(67)60-40)15-9-10-20-51/h4-8,11-14,16-19,24,27,33,35-41,54,62-64H,9-10,15,20-23,25-26,51-52H2,1-3H3,(H2,53,65)(H,55,69)(H,56,70)(H,57,68)(H,58,72)(H,59,66)(H,60,67)(H,61,71)/t27-,33-,35+,36+,37+,38+,39+,40+,41-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020198
(CHEMBL308471 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C47H62N10O9S2/c1-26(58)38-46(66)57-39(40(50)60)47(2,3)68-67-25-37(55-41(61)32(49)21-27-11-5-4-6-12-27)45(65)53-35(22-28-16-18-30(59)19-17-28)43(63)54-36(23-29-24-51-33-14-8-7-13-31(29)33)44(64)52-34(42(62)56-38)15-9-10-20-48/h4-8,11-14,16-19,24,26,32,34-39,51,58-59H,9-10,15,20-23,25,48-49H2,1-3H3,(H2,50,60)(H,52,64)(H,53,65)(H,54,63)(H,55,61)(H,56,62)(H,57,66)/t26-,32-,34+,35+,36+,37+,38+,39-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020200
(CHEMBL405672 | D-Ticc(-Cys-Tyr-D-Typ-Lys-Thr-Pen-)...)Show SMILES CC(C)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C53H71N11O10S2/c1-28(2)42(45(55)67)62-52(74)44-53(4,5)76-75-27-41(61-47(69)38-23-31-12-6-7-13-32(31)25-57-38)50(72)59-39(22-30-17-19-34(66)20-18-30)48(70)60-40(24-33-26-56-36-15-9-8-14-35(33)36)49(71)58-37(16-10-11-21-54)46(68)63-43(29(3)65)51(73)64-44/h6-9,12-15,17-20,26,28-29,37-44,56-57,65-66H,10-11,16,21-25,27,54H2,1-5H3,(H2,55,67)(H,58,71)(H,59,72)(H,60,70)(H,61,69)(H,62,74)(H,63,68)(H,64,73)/t29-,37+,38-,39+,40+,41+,42+,43+,44-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020200
(CHEMBL405672 | D-Ticc(-Cys-Tyr-D-Typ-Lys-Thr-Pen-)...)Show SMILES CC(C)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C53H71N11O10S2/c1-28(2)42(45(55)67)62-52(74)44-53(4,5)76-75-27-41(61-47(69)38-23-31-12-6-7-13-32(31)25-57-38)50(72)59-39(22-30-17-19-34(66)20-18-30)48(70)60-40(24-33-26-56-36-15-9-8-14-35(33)36)49(71)58-37(16-10-11-21-54)46(68)63-43(29(3)65)51(73)64-44/h6-9,12-15,17-20,26,28-29,37-44,56-57,65-66H,10-11,16,21-25,27,54H2,1-5H3,(H2,55,67)(H,58,71)(H,59,72)(H,60,70)(H,61,69)(H,62,74)(H,63,68)(H,64,73)/t29-,37+,38-,39+,40+,41+,42+,43+,44-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020212
(CHEMBL405244 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CC(O)=O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C51H67N11O12S2/c1-27(63)41-49(73)62-42(50(74)57-36(43(54)67)24-40(65)66)51(2,3)76-75-26-39(60-44(68)33(53)21-28-11-5-4-6-12-28)48(72)58-37(22-29-16-18-31(64)19-17-29)46(70)59-38(23-30-25-55-34-14-8-7-13-32(30)34)47(71)56-35(45(69)61-41)15-9-10-20-52/h4-8,11-14,16-19,25,27,33,35-39,41-42,55,63-64H,9-10,15,20-24,26,52-53H2,1-3H3,(H2,54,67)(H,56,71)(H,57,74)(H,58,72)(H,59,70)(H,60,68)(H,61,69)(H,62,73)(H,65,66)/t27-,33-,35+,36+,37+,38+,39+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50016853
(2-{[10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propio...)Show SMILES CC1(C)SSC(C)(C)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccc(cc2)N=[N+]=[N-])C(=O)N[C@H]1C(O)=O Show InChI InChI=1S/C30H38N8O7S2/c1-29(2)23(35-25(41)20(31)13-16-7-11-19(39)12-8-16)27(43)33-15-22(40)34-21(14-17-5-9-18(10-6-17)37-38-32)26(42)36-24(28(44)45)30(3,4)47-46-29/h5-12,20-21,23-24,39H,13-15,31H2,1-4H3,(H,33,43)(H,34,40)(H,35,41)(H,36,42)(H,44,45)/t20-,21-,23+,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding potency of compound in competition with [3H]DPDPE for Opioid receptor delta 1 tested in rat brain membrane |
J Med Chem 32: 638-43 (1989)
BindingDB Entry DOI: 10.7270/Q2DN45N0 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50016853
(2-{[10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propio...)Show SMILES CC1(C)SSC(C)(C)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccc(cc2)N=[N+]=[N-])C(=O)N[C@H]1C(O)=O Show InChI InChI=1S/C30H38N8O7S2/c1-29(2)23(35-25(41)20(31)13-16-7-11-19(39)12-8-16)27(43)33-15-22(40)34-21(14-17-5-9-18(10-6-17)37-38-32)26(42)36-24(28(44)45)30(3,4)47-46-29/h5-12,20-21,23-24,39H,13-15,31H2,1-4H3,(H,33,43)(H,34,40)(H,35,41)(H,36,42)(H,44,45)/t20-,21-,23+,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding potency of compound in competition with [3H]CTOP for Opioid receptor mu 1 tested in rat brain membrane |
J Med Chem 32: 638-43 (1989)
BindingDB Entry DOI: 10.7270/Q2DN45N0 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020205
(CHEMBL216354 | D-Tic-c(Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C51H67N11O11S2/c1-27(64)41-49(72)62-42(50(73)59-39(25-63)43(53)66)51(2,3)75-74-26-40(60-45(68)36-21-29-10-4-5-11-30(29)23-55-36)48(71)57-37(20-28-15-17-32(65)18-16-28)46(69)58-38(22-31-24-54-34-13-7-6-12-33(31)34)47(70)56-35(44(67)61-41)14-8-9-19-52/h4-7,10-13,15-18,24,27,35-42,54-55,63-65H,8-9,14,19-23,25-26,52H2,1-3H3,(H2,53,66)(H,56,70)(H,57,71)(H,58,69)(H,59,73)(H,60,68)(H,61,67)(H,62,72)/t27-,35+,36-,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020206
(CHEMBL266829 | CTOP)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C45H69N11O11S2/c1-24(57)34(37(49)60)54-44(67)36-45(3,4)69-68-23-33(53-38(61)29(48)21-26-11-6-5-7-12-26)42(65)52-32(22-27-15-17-28(59)18-16-27)41(64)51-31(14-10-20-47)39(62)50-30(13-8-9-19-46)40(63)55-35(25(2)58)43(66)56-36/h5-7,11-12,15-18,24-25,29-36,57-59H,8-10,13-14,19-23,46-48H2,1-4H3,(H2,49,60)(H,50,62)(H,51,64)(H,52,65)(H,53,61)(H,54,67)(H,55,63)(H,56,66)/t24-,25-,29+,30+,31+,32+,33+,34+,35+,36-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020214
(CHEMBL302596 | D-Phec(-Cys-Tyr-D-Trp-Lys-D-Pen-)Th...)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(N)=O Show InChI InChI=1S/C47H62N10O9S2/c1-26(58)38(40(50)60)56-46(66)39-47(2,3)68-67-25-37(55-41(61)32(49)21-27-11-5-4-6-12-27)45(65)53-35(22-28-16-18-30(59)19-17-28)43(63)54-36(23-29-24-51-33-14-8-7-13-31(29)33)44(64)52-34(42(62)57-39)15-9-10-20-48/h4-8,11-14,16-19,24,26,32,34-39,51,58-59H,9-10,15,20-23,25,48-49H2,1-3H3,(H2,50,60)(H,52,64)(H,53,65)(H,54,63)(H,55,61)(H,56,66)(H,57,62)/t26-,32+,34+,35+,36+,37+,38+,39+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020201
(CHEMBL303040 | D-Tyrc(-Cys-Phe-Asn-Pen-)Thr-NH2)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C34H46N8O9S2/c1-17(43)26(28(37)46)41-33(51)27-34(2,3)53-52-16-24(40-29(47)21(35)13-19-9-11-20(44)12-10-19)32(50)38-22(14-18-7-5-4-6-8-18)30(48)39-23(15-25(36)45)31(49)42-27/h4-12,17,21-24,26-27,43-44H,13-16,35H2,1-3H3,(H2,36,45)(H2,37,46)(H,38,50)(H,39,48)(H,40,47)(H,41,51)(H,42,49)/t17-,21+,22+,23+,24+,26+,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020196
(CHEMBL419066 | D-Phec(-Cys-Tyr-D-Trp-Thr-D-Pen-_Th...)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O Show InChI InChI=1S/C45H57N9O10S2/c1-23(55)35(38(47)58)52-44(64)37-45(3,4)66-65-22-34(51-39(59)30(46)18-25-10-6-5-7-11-25)42(62)49-32(19-26-14-16-28(57)17-15-26)40(60)50-33(41(61)53-36(24(2)56)43(63)54-37)20-27-21-48-31-13-9-8-12-29(27)31/h5-17,21,23-24,30,32-37,48,55-57H,18-20,22,46H2,1-4H3,(H2,47,58)(H,49,62)(H,50,60)(H,51,59)(H,52,64)(H,53,61)(H,54,63)/t23-,24-,30+,32+,33+,34+,35+,36+,37-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020199
(CHEMBL441164 | D-N-Me-Phec(-Cys-Tyr-D-Trp-Orn-Thr-...)Show SMILES CN[C@H](Cc1ccccc1)C(=O)N[C@H]1CSSC(C)(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O Show InChI InChI=1S/C51H69N11O11S2/c1-27(63)40(43(53)66)60-50(73)42-51(3,4)75-74-26-39(59-45(68)36(54-5)22-29-12-7-6-8-13-29)48(71)57-37(23-30-17-19-32(65)20-18-30)46(69)58-38(24-31-25-55-34-15-10-9-14-33(31)34)47(70)56-35(16-11-21-52)44(67)61-41(28(2)64)49(72)62-42/h6-10,12-15,17-20,25,27-28,35-42,54-55,63-65H,11,16,21-24,26,52H2,1-5H3,(H2,53,66)(H,56,70)(H,57,71)(H,58,69)(H,59,68)(H,60,73)(H,61,67)(H,62,72)/t27-,28-,35+,36-,37+,38+,39+,40+,41+,42-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020212
(CHEMBL405244 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CC(O)=O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C51H67N11O12S2/c1-27(63)41-49(73)62-42(50(74)57-36(43(54)67)24-40(65)66)51(2,3)76-75-26-39(60-44(68)33(53)21-28-11-5-4-6-12-28)48(72)58-37(22-29-16-18-31(64)19-17-29)46(70)59-38(23-30-25-55-34-14-8-7-13-32(30)34)47(71)56-35(45(69)61-41)15-9-10-20-52/h4-8,11-14,16-19,25,27,33,35-39,41-42,55,63-64H,9-10,15,20-24,26,52-53H2,1-3H3,(H2,54,67)(H,56,71)(H,57,74)(H,58,72)(H,59,70)(H,60,68)(H,61,69)(H,62,73)(H,65,66)/t27-,33-,35+,36+,37+,38+,39+,41+,42-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50016854
(2-{[10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propio...)Show SMILES [H][C@]1(NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC(C)(C)[C@@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O Show InChI InChI=1S/C51H68N10O12S2/c1-27(62)40-48(70)61-42(49(71)60-41(28(2)63)50(72)73)51(3,4)75-74-26-39(58-43(65)34(53)22-29-12-6-5-7-13-29)47(69)56-37(23-30-17-19-32(64)20-18-30)45(67)57-38(24-31-25-54-35-15-9-8-14-33(31)35)46(68)55-36(44(66)59-40)16-10-11-21-52/h5-9,12-15,17-20,25,27-28,34,36-42,54,62-64H,10-11,16,21-24,26,52-53H2,1-4H3,(H,55,68)(H,56,69)(H,57,67)(H,58,65)(H,59,66)(H,60,71)(H,61,70)(H,72,73)/t27-,28-,34+,36-,37-,38-,39-,40+,41+,42+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding potency of compound in competition with [3H]DPDPE for Opioid receptor delta 1 tested in rat brain membrane |
J Med Chem 32: 638-43 (1989)
BindingDB Entry DOI: 10.7270/Q2DN45N0 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50016854
(2-{[10-(4-Amino-butyl)-19-(2-amino-3-phenyl-propio...)Show SMILES [H][C@]1(NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC(C)(C)[C@@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O Show InChI InChI=1S/C51H68N10O12S2/c1-27(62)40-48(70)61-42(49(71)60-41(28(2)63)50(72)73)51(3,4)75-74-26-39(58-43(65)34(53)22-29-12-6-5-7-13-29)47(69)56-37(23-30-17-19-32(64)20-18-30)45(67)57-38(24-31-25-54-35-15-9-8-14-33(31)35)46(68)55-36(44(66)59-40)16-10-11-21-52/h5-9,12-15,17-20,25,27-28,34,36-42,54,62-64H,10-11,16,21-24,26,52-53H2,1-4H3,(H,55,68)(H,56,69)(H,57,67)(H,58,65)(H,59,66)(H,60,71)(H,61,70)(H,72,73)/t27-,28-,34+,36-,37-,38-,39-,40+,41+,42+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding potency of compound in competition with [3H]CTOP for Opioid receptor mu 1 tested in rat brain membrane |
J Med Chem 32: 638-43 (1989)
BindingDB Entry DOI: 10.7270/Q2DN45N0 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(RAT) | BDBM50020208
(CHEMBL1795717 | TCTAP)Show SMILES [H][C@](NC(=O)[C@@]1([H])NC(=O)[C@@]([H])(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@]([H])(CSSC1(C)C)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)([C@@H](C)O)C(N)=O |r| Show InChI InChI=1S/C51H69N13O11S2/c1-26(65)39(42(53)68)62-49(75)41-51(3,4)77-76-25-38(61-43(69)33(52)21-28-11-6-5-7-12-28)47(73)59-36(22-29-16-18-31(67)19-17-29)45(71)60-37(23-30-24-57-34-14-9-8-13-32(30)34)46(72)58-35(15-10-20-56-50(54)55)44(70)63-40(27(2)66)48(74)64-41/h5-9,11-14,16-19,24,26-27,33,35-41,57,65-67H,10,15,20-23,25,52H2,1-4H3,(H2,53,68)(H,58,72)(H,59,73)(H,60,71)(H,61,69)(H,62,75)(H,63,70)(H,64,74)(H4,54,55,56)/t26-,27-,33-,35+,36+,37-,38+,39+,40+,41-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50452485
(CHEMBL2369462)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H]1Cc2ccccc2CN1)C(N)=O Show InChI InChI=1S/C48H62N10O9S2/c1-26(59)39(41(50)61)57-47(67)40-48(2,3)69-68-25-38(56-43(63)35-21-28-10-4-5-11-29(28)23-52-35)46(66)54-36(20-27-15-17-31(60)18-16-27)44(64)55-37(22-30-24-51-33-13-7-6-12-32(30)33)45(65)53-34(42(62)58-40)14-8-9-19-49/h4-7,10-13,15-18,24,26,34-40,51-52,59-60H,8-9,14,19-23,25,49H2,1-3H3,(H2,50,61)(H,53,65)(H,54,66)(H,55,64)(H,56,63)(H,57,67)(H,58,62)/t26-,34+,35-,36-,37+,38+,39+,40-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 9.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- CTOP in Opioid receptor mu 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020204
(CHEMBL66403 | D-Phec(-Cys-Tyr-Asn-Pen-)Thr-NH2)Show SMILES C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(N)=O Show InChI InChI=1S/C34H46N8O9S2/c1-17(43)26(28(37)46)41-33(51)27-34(2,3)53-52-16-24(40-29(47)21(35)13-18-7-5-4-6-8-18)32(50)38-22(14-19-9-11-20(44)12-10-19)30(48)39-23(15-25(36)45)31(49)42-27/h4-12,17,21-24,26-27,43-44H,13-16,35H2,1-3H3,(H2,36,45)(H2,37,46)(H,38,50)(H,39,48)(H,40,47)(H,41,51)(H,42,49)/t17-,21+,22+,23+,24+,26+,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020212
(CHEMBL405244 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CC(O)=O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C51H67N11O12S2/c1-27(63)41-49(73)62-42(50(74)57-36(43(54)67)24-40(65)66)51(2,3)76-75-26-39(60-44(68)33(53)21-28-11-5-4-6-12-28)48(72)58-37(22-29-16-18-31(64)19-17-29)46(70)59-38(23-30-25-55-34-14-8-7-13-32(30)34)47(71)56-35(45(69)61-41)15-9-10-20-52/h4-8,11-14,16-19,25,27,33,35-39,41-42,55,63-64H,9-10,15,20-24,26,52-53H2,1-3H3,(H2,54,67)(H,56,71)(H,57,74)(H,58,72)(H,59,70)(H,60,68)(H,61,69)(H,62,73)(H,65,66)/t27-,33-,35+,36+,37+,38+,39+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50020211
(CHEMBL216353 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C51H68N12O11S2/c1-27(64)41-49(73)63-42(50(74)58-36(43(55)67)24-40(54)66)51(2,3)76-75-26-39(61-44(68)33(53)21-28-11-5-4-6-12-28)48(72)59-37(22-29-16-18-31(65)19-17-29)46(70)60-38(23-30-25-56-34-14-8-7-13-32(30)34)47(71)57-35(45(69)62-41)15-9-10-20-52/h4-8,11-14,16-19,25,27,33,35-39,41-42,56,64-65H,9-10,15,20-24,26,52-53H2,1-3H3,(H2,54,66)(H2,55,67)(H,57,71)(H,58,74)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,63,73)/t27-,33-,35+,36+,37+,38+,39+,41+,42-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description
Binding affinity in competition with [3H]- DPDPE in Opioid receptor delta 1 binding to rat brain membrane |
J Med Chem 31: 2170-7 (1988)
BindingDB Entry DOI: 10.7270/Q2J38RJX |
More data for this
Ligand-Target Pair | |
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