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Compile Data Set for Download or QSAR

Found 7 hits with Last Name = 'solhi' and Initial = 'h'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificity protein kinase CLK1


(Homo sapiens (Human))
BDBM50435473
PNG
(CHEMBL1236620)
Show SMILES CCOC(=O)c1c(C(C=N)C#N)c2ccc(Cl)c(Cl)c2n1C
Show InChI InChI=1S/C15H13Cl2N3O2/c1-3-22-15(21)14-11(8(6-18)7-19)9-4-5-10(16)12(17)13(9)20(14)2/h4-6,8,18H,3H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human CLK1 (130 to end residues) using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of [gamma33P-ATP] by...


Citation and Details

Article DOI: 10.1016/j.bmc.2020.115962
BindingDB Entry DOI: 10.7270/Q2KD22JS
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK1


(Homo sapiens (Human))
BDBM50552555
PNG
(CHEMBL4783398)
Show SMILES Cc1ccc(c(c1)[N+]([O-])=O)-n1cc(COc2cccc3cnc(Nc4cccc(Cl)c4)nc23)nn1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 11n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human CLK1 (130 to end residues) using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of [gamma33P-ATP] by...


Citation and Details

Article DOI: 10.1016/j.bmc.2020.115962
BindingDB Entry DOI: 10.7270/Q2KD22JS
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK4


(Homo sapiens (Human))
BDBM50552555
PNG
(CHEMBL4783398)
Show SMILES Cc1ccc(c(c1)[N+]([O-])=O)-n1cc(COc2cccc3cnc(Nc4cccc(Cl)c4)nc23)nn1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human CLK4 (128 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam...


Citation and Details

Article DOI: 10.1016/j.bmc.2020.115962
BindingDB Entry DOI: 10.7270/Q2KD22JS
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK2


(Homo sapiens (Human))
BDBM50552555
PNG
(CHEMBL4783398)
Show SMILES Cc1ccc(c(c1)[N+]([O-])=O)-n1cc(COc2cccc3cnc(Nc4cccc(Cl)c4)nc23)nn1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 27n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human CLK2 (138 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam...


Citation and Details

Article DOI: 10.1016/j.bmc.2020.115962
BindingDB Entry DOI: 10.7270/Q2KD22JS
More data for this
Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A


(RAT)
BDBM50552555
PNG
(CHEMBL4783398)
Show SMILES Cc1ccc(c(c1)[N+]([O-])=O)-n1cc(COc2cccc3cnc(Nc4cccc(Cl)c4)nc23)nn1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 120n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat DYRK1A (1 to 499 residues) assessed as residual activity by ADP-Glo assay


Citation and Details

Article DOI: 10.1016/j.bmc.2020.115962
BindingDB Entry DOI: 10.7270/Q2KD22JS
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK3


(Homo sapiens (Human))
BDBM50552555
PNG
(CHEMBL4783398)
Show SMILES Cc1ccc(c(c1)[N+]([O-])=O)-n1cc(COc2cccc3cnc(Nc4cccc(Cl)c4)nc23)nn1
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.28E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human full length CLK3 using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of [gamma33P-ATP] by scintilla...


Citation and Details

Article DOI: 10.1016/j.bmc.2020.115962
BindingDB Entry DOI: 10.7270/Q2KD22JS
More data for this
Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A


(RAT)
BDBM50552556
PNG
(CHEMBL4758072)
Show SMILES Cc1ccc(cc1[N+]([O-])=O)-n1cc(COc2cccc3cnc(Nc4cccc(Cl)c4)nc23)nn1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat DYRK1A (1 to 499 residues) assessed as residual activity by ADP-Glo assay


Citation and Details

Article DOI: 10.1016/j.bmc.2020.115962
BindingDB Entry DOI: 10.7270/Q2KD22JS
More data for this
Ligand-Target Pair