Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Dual specificity protein kinase CLK1 (Homo sapiens (Human)) | BDBM50435473 (CHEMBL1236620) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human CLK1 (130 to end residues) using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of [gamma33P-ATP] by... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115962 BindingDB Entry DOI: 10.7270/Q2KD22JS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK1 (Homo sapiens (Human)) | BDBM50552555 (CHEMBL4783398) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human CLK1 (130 to end residues) using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of [gamma33P-ATP] by... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115962 BindingDB Entry DOI: 10.7270/Q2KD22JS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK4 (Homo sapiens (Human)) | BDBM50552555 (CHEMBL4783398) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human CLK4 (128 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115962 BindingDB Entry DOI: 10.7270/Q2KD22JS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK2 (Homo sapiens (Human)) | BDBM50552555 (CHEMBL4783398) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human CLK2 (138 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115962 BindingDB Entry DOI: 10.7270/Q2KD22JS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT) | BDBM50552555 (CHEMBL4783398) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat DYRK1A (1 to 499 residues) assessed as residual activity by ADP-Glo assay | Citation and Details Article DOI: 10.1016/j.bmc.2020.115962 BindingDB Entry DOI: 10.7270/Q2KD22JS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK3 (Homo sapiens (Human)) | BDBM50552555 (CHEMBL4783398) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human full length CLK3 using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of [gamma33P-ATP] by scintilla... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115962 BindingDB Entry DOI: 10.7270/Q2KD22JS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT) | BDBM50552556 (CHEMBL4758072) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat DYRK1A (1 to 499 residues) assessed as residual activity by ADP-Glo assay | Citation and Details Article DOI: 10.1016/j.bmc.2020.115962 BindingDB Entry DOI: 10.7270/Q2KD22JS | |||||||||||
More data for this Ligand-Target Pair |