Found 251 hits with Last Name = 'soliman' and Initial = 'dh' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504750
(CHEMBL4536202)Show SMILES COC(=O)c1nn(-c2ccc(cc2)S(N)(=O)=O)c2nc3cc(cc(-c4ccc(cc4)[N+]([O-])=O)c3c(=O)n12)-c1cccs1 Show InChI InChI=1S/C27H18N6O7S2/c1-40-26(35)24-30-32(17-8-10-19(11-9-17)42(28,38)39)27-29-21-14-16(22-3-2-12-41-22)13-20(23(21)25(34)31(24)27)15-4-6-18(7-5-15)33(36)37/h2-14H,1H3,(H2,28,38,39) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504776
(CHEMBL4441461)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(C(=O)N\N=C(\CC(=O)c2ccccn2)C(F)(F)F)c1-c1ccccc1 Show InChI InChI=1S/C24H18F3N7O4S/c25-24(26,27)20(14-19(35)18-8-4-5-13-29-18)30-32-23(36)21-22(15-6-2-1-3-7-15)34(33-31-21)16-9-11-17(12-10-16)39(28,37)38/h1-13H,14H2,(H,32,36)(H2,28,37,38)/b30-20- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504771
(CHEMBL4529889)Show SMILES COc1ccc(NC(=O)Nc2nc(N)n(n2)-c2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C16H17N7O4S/c1-27-12-6-2-10(3-7-12)19-16(24)21-15-20-14(17)23(22-15)11-4-8-13(9-5-11)28(18,25)26/h2-9H,1H3,(H2,18,25,26)(H4,17,19,20,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504755
(CHEMBL4552517)Show SMILES Cc1ccc(NC(=O)Nc2nc(N)n(n2)-c2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C16H17N7O3S/c1-10-2-4-11(5-3-10)19-16(24)21-15-20-14(17)23(22-15)12-6-8-13(9-7-12)27(18,25)26/h2-9H,1H3,(H2,18,25,26)(H4,17,19,20,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50504759
(CHEMBL4587956)Show SMILES Nc1nc(NC(=O)Nc2ccc(cc2)S(N)(=O)=O)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H16N8O5S2/c16-13-20-14(22-23(13)10-3-7-12(8-4-10)30(18,27)28)21-15(24)19-9-1-5-11(6-2-9)29(17,25)26/h1-8H,(H2,17,25,26)(H2,18,27,28)(H4,16,19,20,21,22,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50334354
(4-(3-(4-fluorophenyl)ureido)benzenesulfonamide | 4...)Show InChI InChI=1S/C13H12FN3O3S/c14-9-1-3-10(4-2-9)16-13(18)17-11-5-7-12(8-6-11)21(15,19)20/h1-8H,(H2,15,19,20)(H2,16,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504765
(CHEMBL4446087)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)NNC(=O)Nc1ccccc1 Show InChI InChI=1S/C16H16N8O4S/c17-15-20-13(14(25)21-22-16(26)19-10-4-2-1-3-5-10)23-24(15)11-6-8-12(9-7-11)29(18,27)28/h1-9H,(H,21,25)(H2,17,20,23)(H2,18,27,28)(H2,19,22,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50551112
(CHEMBL4751980)Show SMILES COc1ccc(cc1)-c1ccnc2c(\N=N\c3ccc(cc3)S(N)(=O)=O)c(N)nn12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 12 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504754
(CHEMBL4561594)Show SMILES C\C(=N/NC(=O)c1nc(N)n(n1)-c1ccc(cc1)S(N)(=O)=O)c1ccncc1 Show InChI InChI=1S/C16H16N8O3S/c1-10(11-6-8-19-9-7-11)21-22-15(25)14-20-16(17)24(23-14)12-2-4-13(5-3-12)28(18,26)27/h2-9H,1H3,(H,22,25)(H2,17,20,23)(H2,18,26,27)/b21-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50551109
(CHEMBL4790806)Show SMILES Nc1nn2c(ccnc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(F)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50551108
(CHEMBL4758858)Show SMILES Cc1ccc(cc1)-c1ccnc2c(\N=N\c3ccc(cc3)S(N)(=O)=O)c(N)nn12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504764
(CHEMBL4462487)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)N\N=C\c1cccnc1 Show InChI InChI=1S/C15H14N8O3S/c16-15-20-13(14(24)21-19-9-10-2-1-7-18-8-10)22-23(15)11-3-5-12(6-4-11)27(17,25)26/h1-9H,(H,21,24)(H2,16,20,22)(H2,17,25,26)/b19-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504757
(CHEMBL4555991)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)N\N=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C16H14ClN7O3S/c17-11-3-1-10(2-4-11)9-20-22-15(25)14-21-16(18)24(23-14)12-5-7-13(8-6-12)28(19,26)27/h1-9H,(H,22,25)(H2,18,21,23)(H2,19,26,27)/b20-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50551114
(CHEMBL4762561)Show SMILES Nc1nn2c(ccnc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1cccs1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50504777
(CHEMBL4559106)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)N\N=C\c1ccc(O)cc1 Show InChI InChI=1S/C16H15N7O4S/c17-16-20-14(15(25)21-19-9-10-1-5-12(24)6-2-10)22-23(16)11-3-7-13(8-4-11)28(18,26)27/h1-9,24H,(H,21,25)(H2,17,20,22)(H2,18,26,27)/b19-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504770
(CHEMBL4470233)Show SMILES Nc1nc(NC(=O)Nc2ccc(F)cc2)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H14FN7O3S/c16-9-1-3-10(4-2-9)19-15(24)21-14-20-13(17)23(22-14)11-5-7-12(8-6-11)27(18,25)26/h1-8H,(H2,18,25,26)(H4,17,19,20,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50504753
(CHEMBL4585562)Show SMILES Nc1nc(NC(=O)Nc2ccccc2)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H15N7O3S/c16-13-19-14(20-15(23)18-10-4-2-1-3-5-10)21-22(13)11-6-8-12(9-7-11)26(17,24)25/h1-9H,(H2,17,24,25)(H4,16,18,19,20,21,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504753
(CHEMBL4585562)Show SMILES Nc1nc(NC(=O)Nc2ccccc2)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H15N7O3S/c16-13-19-14(20-15(23)18-10-4-2-1-3-5-10)21-22(13)11-6-8-12(9-7-11)26(17,24)25/h1-9H,(H2,17,24,25)(H4,16,18,19,20,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50504757
(CHEMBL4555991)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)N\N=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C16H14ClN7O3S/c17-11-3-1-10(2-4-11)9-20-22-15(25)14-21-16(18)24(23-14)12-5-7-13(8-6-12)28(19,26)27/h1-9H,(H,22,25)(H2,18,21,23)(H2,19,26,27)/b20-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504777
(CHEMBL4559106)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)N\N=C\c1ccc(O)cc1 Show InChI InChI=1S/C16H15N7O4S/c17-16-20-14(15(25)21-19-9-10-1-5-12(24)6-2-10)22-23(16)11-3-7-13(8-4-11)28(18,26)27/h1-9,24H,(H,21,25)(H2,17,20,22)(H2,18,26,27)/b19-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504754
(CHEMBL4561594)Show SMILES C\C(=N/NC(=O)c1nc(N)n(n1)-c1ccc(cc1)S(N)(=O)=O)c1ccncc1 Show InChI InChI=1S/C16H16N8O3S/c1-10(11-6-8-19-9-7-11)21-22-15(25)14-20-16(17)24(23-14)12-2-4-13(5-3-12)28(18,26)27/h2-9H,1H3,(H,22,25)(H2,17,20,23)(H2,18,26,27)/b21-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50551117
(CHEMBL4786073)Show SMILES Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(F)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504777
(CHEMBL4559106)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)N\N=C\c1ccc(O)cc1 Show InChI InChI=1S/C16H15N7O4S/c17-16-20-14(15(25)21-19-9-10-1-5-12(24)6-2-10)22-23(16)11-3-7-13(8-4-11)28(18,26)27/h1-9,24H,(H,21,25)(H2,17,20,22)(H2,18,26,27)/b19-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504773
(CHEMBL4520887)Show SMILES C\C(=N/NC(=O)c1nc(N)n(n1)-c1ccc(cc1)S(N)(=O)=O)c1ccccc1 Show InChI InChI=1S/C17H17N7O3S/c1-11(12-5-3-2-4-6-12)21-22-16(25)15-20-17(18)24(23-15)13-7-9-14(10-8-13)28(19,26)27/h2-10H,1H3,(H,22,25)(H2,18,20,23)(H2,19,26,27)/b21-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50551103
(CHEMBL4784840)Show SMILES Cc1ccc(cc1)-c1cn2nc(N)c(\N=N\c3ccc(cc3)S(N)(=O)=O)c2[nH]1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504767
(CHEMBL4458902)Show SMILES Nc1nc(NC(=O)Nc2ccc(Cl)cc2)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H14ClN7O3S/c16-9-1-3-10(4-2-9)19-15(24)21-14-20-13(17)23(22-14)11-5-7-12(8-6-11)27(18,25)26/h1-8H,(H2,18,25,26)(H4,17,19,20,21,22,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504774
(CHEMBL4455591)Show SMILES Nc1nc(NC(=O)Nc2ccc(cc2)C(O)=O)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H15N7O5S/c17-14-20-15(21-16(26)19-10-3-1-9(2-4-10)13(24)25)22-23(14)11-5-7-12(8-6-11)29(18,27)28/h1-8H,(H,24,25)(H2,18,27,28)(H4,17,19,20,21,22,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 9.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504779
(CHEMBL4530650)Show SMILES CC(=O)OC[C@@H]1O[C@@H](OCc2cn(nn2)-c2ccc(cc2)S(N)(=O)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O |r| Show InChI InChI=1S/C23H28N4O12S/c1-12(28)34-11-19-20(36-13(2)29)21(37-14(3)30)22(38-15(4)31)23(39-19)35-10-16-9-27(26-25-16)17-5-7-18(8-6-17)40(24,32)33/h5-9,19-23H,10-11H2,1-4H3,(H2,24,32,33)/t19-,20-,21+,22-,23+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 9.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504778
(CHEMBL4441389)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)NNC(=S)Nc1ccccc1 Show InChI InChI=1S/C16H16N8O3S2/c17-15-20-13(14(25)21-22-16(28)19-10-4-2-1-3-5-10)23-24(15)11-6-8-12(9-7-11)29(18,26)27/h1-9H,(H,21,25)(H2,17,20,23)(H2,18,26,27)(H2,19,22,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 9.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50504771
(CHEMBL4529889)Show SMILES COc1ccc(NC(=O)Nc2nc(N)n(n2)-c2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C16H17N7O4S/c1-27-12-6-2-10(3-7-12)19-16(24)21-15-20-14(17)23(22-15)11-4-8-13(9-5-11)28(18,25)26/h2-9H,1H3,(H2,18,25,26)(H4,17,19,20,21,22,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504753
(CHEMBL4585562)Show SMILES Nc1nc(NC(=O)Nc2ccccc2)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H15N7O3S/c16-13-19-14(20-15(23)18-10-4-2-1-3-5-10)21-22(13)11-6-8-12(9-7-11)26(17,24)25/h1-9H,(H2,17,24,25)(H4,16,18,19,20,21,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50504758
(CHEMBL4578451)Show SMILES C\C(=N/NC(=O)c1nc(N)n(n1)-c1ccc(cc1)S(N)(=O)=O)c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C21H24N8O4S/c1-14(15-2-4-16(5-3-15)28-10-12-33-13-11-28)25-26-20(30)19-24-21(22)29(27-19)17-6-8-18(9-7-17)34(23,31)32/h2-9H,10-13H2,1H3,(H,26,30)(H2,22,24,27)(H2,23,31,32)/b25-14+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 9.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50343660
(4-((3,5-diamino-1H-pyrazol-4-yl)diazenyl)benzenesu...)Show InChI InChI=1S/C9H11N7O2S/c10-8-7(9(11)16-15-8)14-13-5-1-3-6(4-2-5)19(12,17)18/h1-4H,(H2,12,17,18)(H5,10,11,15,16)/b14-13+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 12 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50504769
(CHEMBL4458130)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)N\N=C\c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H14N8O5S/c17-16-20-14(22-23(16)11-5-7-13(8-6-11)30(18,28)29)15(25)21-19-9-10-1-3-12(4-2-10)24(26)27/h1-9H,(H,21,25)(H2,17,20,22)(H2,18,28,29)/b19-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50551117
(CHEMBL4786073)Show SMILES Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(F)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 12 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504766
(CHEMBL4538508)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)NNC(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C16H15ClN8O4S/c17-9-1-3-10(4-2-9)20-16(27)23-22-14(26)13-21-15(18)25(24-13)11-5-7-12(8-6-11)30(19,28)29/h1-8H,(H,22,26)(H2,18,21,24)(H2,19,28,29)(H2,20,23,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50504747
(CHEMBL4452122)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)NNC(=S)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C16H15ClN8O3S2/c17-9-1-3-10(4-2-9)20-16(29)23-22-14(26)13-21-15(18)25(24-13)11-5-7-12(8-6-11)30(19,27)28/h1-8H,(H,22,26)(H2,18,21,24)(H2,19,27,28)(H2,20,23,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank MMDB PDB Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank MMDB PDB Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50551118
(CHEMBL4741017)Show SMILES Nc1nn2c(N)c(C#N)c(nc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 12 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50551113
(CHEMBL4790351)Show SMILES Nc1nn2c(ccnc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(cc1)[N+]([O-])=O | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 12 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504774
(CHEMBL4455591)Show SMILES Nc1nc(NC(=O)Nc2ccc(cc2)C(O)=O)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H15N7O5S/c17-14-20-15(21-16(26)19-10-3-1-9(2-4-10)13(24)25)22-23(14)11-5-7-12(8-6-11)29(18,27)28/h1-8H,(H,24,25)(H2,18,27,28)(H4,17,19,20,21,22,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50551109
(CHEMBL4790806)Show SMILES Nc1nn2c(ccnc2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(F)cc1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50504765
(CHEMBL4446087)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)NNC(=O)Nc1ccccc1 Show InChI InChI=1S/C16H16N8O4S/c17-15-20-13(14(25)21-22-16(26)19-10-4-2-1-3-5-10)23-24(15)11-6-8-12(9-7-11)29(18,27)28/h1-9H,(H,21,25)(H2,17,20,23)(H2,18,27,28)(H2,19,22,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504766
(CHEMBL4538508)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)NNC(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C16H15ClN8O4S/c17-9-1-3-10(4-2-9)20-16(27)23-22-14(26)13-21-15(18)25(24-13)11-5-7-12(8-6-11)30(19,28)29/h1-8H,(H,22,26)(H2,18,21,24)(H2,19,28,29)(H2,20,23,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50504747
(CHEMBL4452122)Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)NNC(=S)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C16H15ClN8O3S2/c17-9-1-3-10(4-2-9)20-16(29)23-22-14(26)13-21-15(18)25(24-13)11-5-7-12(8-6-11)30(19,27)28/h1-8H,(H,22,26)(H2,18,21,24)(H2,19,27,28)(H2,20,23,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50551105
(CHEMBL4747175)Show SMILES Nc1nn2cc([nH]c2c1\N=N\c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydrase assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.112019 BindingDB Entry DOI: 10.7270/Q2Z3238X |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50504770
(CHEMBL4470233)Show SMILES Nc1nc(NC(=O)Nc2ccc(F)cc2)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H14FN7O3S/c16-9-1-3-10(4-2-9)19-15(24)21-14-20-13(17)23(22-14)11-5-7-12(8-6-11)27(18,25)26/h1-8H,(H2,18,25,26)(H4,17,19,20,21,22,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Russian University
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assay |
Eur J Med Chem 185: (2020)
Article DOI: 10.1016/j.ejmech.2019.111843 BindingDB Entry DOI: 10.7270/Q2WW7N05 |
More data for this Ligand-Target Pair | |