Compile Data Set for Download or QSAR

Found 7 hits with Last Name = 'stephanski' and Initial = 'kj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50090910 (3alpha,16,17,18-tetrahydroxyaphidicolone | 6,13-di...) Show SMILES C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]1C[C@@H]3C[C@]21CC[C@]3(O)CO |r| Show InChI InChI=1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Inhibition of human DNA polymerase alpha				Bioorg Med Chem Lett 20: 3039-42 (2010) Article DOI: 10.1016/j.bmcl.2010.03.115 BindingDB Entry DOI: 10.7270/Q2000281
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50313783 (CHEMBL1092799 | N-(4-chlorobenzyl)-1-methyl-9-(mor...) Show SMILES CN1C(=O)Cn2cc(C(=O)NCc3ccc(Cl)cc3)c(=O)c3cc(CN4CCOCC4)cc1c23 Show InChI InChI=1S/C25H25ClN4O4/c1-28-21-11-17(13-29-6-8-34-9-7-29)10-19-23(21)30(15-22(28)31)14-20(24(19)32)25(33)27-12-16-2-4-18(26)5-3-16/h2-5,10-11,14H,6-9,12-13,15H2,1H3,(H,27,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant DNA polymerase alpha expressed in baculovirus infected SF9 cells after 12 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 1994-2000 (2010) Article DOI: 10.1016/j.bmcl.2010.01.094 BindingDB Entry DOI: 10.7270/Q26Q1XDN
					More data for this Ligand-Target Pair
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50313784 ((R)-9-(((2-(benzofuran-2-yl)-2-hydroxyethyl)(methy...) Show SMILES CN(C[C@@H](O)c1cc2ccccc2o1)Cc1cc2N(C)C(=O)Cn3cc(C(=O)NCc4ccc(Cl)cc4)c(=O)c(c1)c23 |r| Show InChI InChI=1S/C32H29ClN4O5/c1-35(17-26(38)28-13-21-5-3-4-6-27(21)42-28)15-20-11-23-30-25(12-20)36(2)29(39)18-37(30)16-24(31(23)40)32(41)34-14-19-7-9-22(33)10-8-19/h3-13,16,26,38H,14-15,17-18H2,1-2H3,(H,34,41)/t26-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant DNA polymerase alpha expressed in baculovirus infected SF9 cells after 12 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 1994-2000 (2010) Article DOI: 10.1016/j.bmcl.2010.01.094 BindingDB Entry DOI: 10.7270/Q26Q1XDN
					More data for this Ligand-Target Pair
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50318171 (2-{2-[bis(2-hydroxyethyl)amino]ethyl}-N-(4-chlorob...) Show SMILES OCCN(CCO)CCc1cc2cc(CN3CCOCC3)cc3c2n1cc(C(=O)NCc1ccc(Cl)cc1)c3=O Show InChI InChI=1S/C30H35ClN4O5/c31-24-3-1-21(2-4-24)18-32-30(39)27-20-35-25(5-6-33(7-11-36)8-12-37)17-23-15-22(16-26(28(23)35)29(27)38)19-34-9-13-40-14-10-34/h1-4,15-17,20,36-37H,5-14,18-19H2,(H,32,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Inhibition of human DNA polymerase alpha				Bioorg Med Chem Lett 20: 3039-42 (2010) Article DOI: 10.1016/j.bmcl.2010.03.115 BindingDB Entry DOI: 10.7270/Q2000281
					More data for this Ligand-Target Pair
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50318172 (CHEMBL1095087 | N-(4-chlorobenzyl)-2-(2-morpholin-...) Show SMILES Clc1ccc(CNC(=O)c2cn3c(CCN4CCOCC4)cc4cc(CN5CCOCC5)cc(c34)c2=O)cc1 Show InChI InChI=1S/C30H33ClN4O4/c31-24-3-1-21(2-4-24)18-32-30(37)27-20-35-25(5-6-33-7-11-38-12-8-33)17-23-15-22(16-26(28(23)35)29(27)36)19-34-9-13-39-14-10-34/h1-4,15-17,20H,5-14,18-19H2,(H,32,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Inhibition of human DNA polymerase alpha				Bioorg Med Chem Lett 20: 3039-42 (2010) Article DOI: 10.1016/j.bmcl.2010.03.115 BindingDB Entry DOI: 10.7270/Q2000281
					More data for this Ligand-Target Pair
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50318169 (CHEMBL1097364 | N-(4-chlorobenzyl)-2-(2-hydroxyeth...) Show SMILES OCCc1cc2cc(CN3CCOCC3)cc3c2n1cc(C(=O)NCc1ccc(Cl)cc1)c3=O Show InChI InChI=1S/C26H26ClN3O4/c27-20-3-1-17(2-4-20)14-28-26(33)23-16-30-21(5-8-31)13-19-11-18(12-22(24(19)30)25(23)32)15-29-6-9-34-10-7-29/h1-4,11-13,16,31H,5-10,14-15H2,(H,28,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Inhibition of human DNA polymerase alpha				Bioorg Med Chem Lett 20: 3039-42 (2010) Article DOI: 10.1016/j.bmcl.2010.03.115 BindingDB Entry DOI: 10.7270/Q2000281
					More data for this Ligand-Target Pair
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50318170 (CHEMBL1095387 | N-(4-Chlorobenzyl)-2-[(2-hydroxyet...) Show SMILES OCCOCc1cc2cc(CN3CCOCC3)cc3c2n1cc(C(=O)NCc1ccc(Cl)cc1)c3=O Show InChI InChI=1S/C27H28ClN3O5/c28-21-3-1-18(2-4-21)14-29-27(34)24-16-31-22(17-36-10-7-32)13-20-11-19(12-23(25(20)31)26(24)33)15-30-5-8-35-9-6-30/h1-4,11-13,16,32H,5-10,14-15,17H2,(H,29,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Inhibition of human DNA polymerase alpha				Bioorg Med Chem Lett 20: 3039-42 (2010) Article DOI: 10.1016/j.bmcl.2010.03.115 BindingDB Entry DOI: 10.7270/Q2000281
					More data for this Ligand-Target Pair