Found 2645 hits with Last Name = 'tarr' and Initial = 'jc' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50521464
(CHEMBL4469869 | US11596639, Example 78)Show SMILES C[C@@H]1CN(c2cn(C)c3ccc(cc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(56.68,-29.59,;57.58,-30.84,;59.12,-30.68,;60.03,-31.93,;61.56,-31.92,;62.47,-30.67,;63.93,-31.14,;65.17,-30.23,;63.94,-32.67,;65.08,-33.69,;64.77,-35.19,;63.31,-35.68,;62.16,-34.65,;62.48,-33.15,;63,-37.18,;64.15,-38.21,;61.54,-37.67,;59.4,-33.33,;60.3,-34.58,;57.87,-33.49,;56.97,-34.74,;56.95,-36.28,;58.28,-37.06,;58.26,-38.6,;59.59,-39.38,;59.57,-40.92,;60.89,-41.7,;60.89,-43.23,;62.22,-44.01,;59.54,-44,;59.53,-45.54,;58.21,-43.21,;56.87,-43.97,;58.23,-41.67,;55.5,-34.27,;54.17,-35.04,;52.83,-34.27,;52.83,-32.73,;51.5,-31.96,;54.16,-31.96,;54.15,-29.06,;52.9,-28.16,;51.44,-28.64,;53.37,-26.7,;54.91,-26.69,;55.82,-25.44,;55.39,-28.15,;56.86,-28.63,;55.5,-32.72,;56.96,-32.25,)| Show InChI InChI=1S/C39H39Cl2N5O4/c1-20-15-26(16-21(2)35(20)41)50-14-8-9-27-28-11-12-30(40)34(33-23(4)42-44(7)24(33)5)36(28)46-22(3)18-45(38(47)37(27)46)32-19-43(6)31-13-10-25(39(48)49)17-29(31)32/h10-13,15-17,19,22H,8-9,14,18H2,1-7H3,(H,48,49)/t22-/m1/s1 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assay |
J Med Chem 62: 3971-3988 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01991
BindingDB Entry DOI: 10.7270/Q2V69P04 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50521464
(CHEMBL4469869 | US11596639, Example 78)Show SMILES C[C@@H]1CN(c2cn(C)c3ccc(cc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(56.68,-29.59,;57.58,-30.84,;59.12,-30.68,;60.03,-31.93,;61.56,-31.92,;62.47,-30.67,;63.93,-31.14,;65.17,-30.23,;63.94,-32.67,;65.08,-33.69,;64.77,-35.19,;63.31,-35.68,;62.16,-34.65,;62.48,-33.15,;63,-37.18,;64.15,-38.21,;61.54,-37.67,;59.4,-33.33,;60.3,-34.58,;57.87,-33.49,;56.97,-34.74,;56.95,-36.28,;58.28,-37.06,;58.26,-38.6,;59.59,-39.38,;59.57,-40.92,;60.89,-41.7,;60.89,-43.23,;62.22,-44.01,;59.54,-44,;59.53,-45.54,;58.21,-43.21,;56.87,-43.97,;58.23,-41.67,;55.5,-34.27,;54.17,-35.04,;52.83,-34.27,;52.83,-32.73,;51.5,-31.96,;54.16,-31.96,;54.15,-29.06,;52.9,-28.16,;51.44,-28.64,;53.37,-26.7,;54.91,-26.69,;55.82,-25.44,;55.39,-28.15,;56.86,-28.63,;55.5,-32.72,;56.96,-32.25,)| Show InChI InChI=1S/C39H39Cl2N5O4/c1-20-15-26(16-21(2)35(20)41)50-14-8-9-27-28-11-12-30(40)34(33-23(4)42-44(7)24(33)5)36(28)46-22(3)18-45(38(47)37(27)46)32-19-43(6)31-13-10-25(39(48)49)17-29(31)32/h10-13,15-17,19,22H,8-9,14,18H2,1-7H3,(H,48,49)/t22-/m1/s1 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assay |
J Med Chem 62: 3971-3988 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01991
BindingDB Entry DOI: 10.7270/Q2V69P04 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50521464
(CHEMBL4469869 | US11596639, Example 78)Show SMILES C[C@@H]1CN(c2cn(C)c3ccc(cc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(56.68,-29.59,;57.58,-30.84,;59.12,-30.68,;60.03,-31.93,;61.56,-31.92,;62.47,-30.67,;63.93,-31.14,;65.17,-30.23,;63.94,-32.67,;65.08,-33.69,;64.77,-35.19,;63.31,-35.68,;62.16,-34.65,;62.48,-33.15,;63,-37.18,;64.15,-38.21,;61.54,-37.67,;59.4,-33.33,;60.3,-34.58,;57.87,-33.49,;56.97,-34.74,;56.95,-36.28,;58.28,-37.06,;58.26,-38.6,;59.59,-39.38,;59.57,-40.92,;60.89,-41.7,;60.89,-43.23,;62.22,-44.01,;59.54,-44,;59.53,-45.54,;58.21,-43.21,;56.87,-43.97,;58.23,-41.67,;55.5,-34.27,;54.17,-35.04,;52.83,-34.27,;52.83,-32.73,;51.5,-31.96,;54.16,-31.96,;54.15,-29.06,;52.9,-28.16,;51.44,-28.64,;53.37,-26.7,;54.91,-26.69,;55.82,-25.44,;55.39,-28.15,;56.86,-28.63,;55.5,-32.72,;56.96,-32.25,)| Show InChI InChI=1S/C39H39Cl2N5O4/c1-20-15-26(16-21(2)35(20)41)50-14-8-9-27-28-11-12-30(40)34(33-23(4)42-44(7)24(33)5)36(28)46-22(3)18-45(38(47)37(27)46)32-19-43(6)31-13-10-25(39(48)49)17-29(31)32/h10-13,15-17,19,22H,8-9,14,18H2,1-7H3,(H,48,49)/t22-/m1/s1 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assay |
J Med Chem 62: 3971-3988 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01991
BindingDB Entry DOI: 10.7270/Q2V69P04 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50521465
(CHEMBL4449014 | US11596639, Example 88)Show SMILES C[C@@H]1CN(c2cn(C)c3cc(ccc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(7.6,-25.05,;8.51,-26.3,;10.05,-26.14,;10.96,-27.38,;12.49,-27.38,;13.4,-26.13,;14.86,-26.6,;16.1,-25.69,;14.86,-28.13,;16.01,-29.15,;15.7,-30.65,;14.24,-31.13,;13.09,-30.11,;13.41,-28.61,;16.85,-31.67,;16.54,-33.18,;18.31,-31.18,;10.33,-28.79,;11.23,-30.04,;8.8,-28.95,;7.89,-30.2,;7.88,-31.73,;9.21,-32.52,;9.19,-34.06,;10.52,-34.84,;10.5,-36.38,;11.82,-37.15,;11.81,-38.69,;13.15,-39.47,;10.47,-39.45,;10.46,-40.99,;9.14,-38.67,;7.8,-39.43,;9.16,-37.13,;6.43,-29.72,;5.09,-30.5,;3.76,-29.73,;3.76,-28.19,;2.43,-27.42,;5.09,-27.42,;5.08,-24.52,;3.83,-23.62,;2.37,-24.1,;4.3,-22.15,;5.84,-22.15,;6.74,-20.9,;6.32,-23.61,;7.79,-24.08,;6.43,-28.18,;7.89,-27.7,)| Show InChI InChI=1S/C39H39Cl2N5O4/c1-20-15-26(16-21(2)35(20)41)50-14-8-9-27-28-12-13-30(40)34(33-23(4)42-44(7)24(33)5)36(28)46-22(3)18-45(38(47)37(27)46)32-19-43(6)31-17-25(39(48)49)10-11-29(31)32/h10-13,15-17,19,22H,8-9,14,18H2,1-7H3,(H,48,49)/t22-/m1/s1 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.0810 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assay |
J Med Chem 62: 3971-3988 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01991
BindingDB Entry DOI: 10.7270/Q2V69P04 |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50244166
(CHEMBL4067929 | US11596639, Example 80)Show SMILES Cc1nn(C)c(C)c1-c1c(Cl)ccc2c(CCCOc3cc(C)c(Cl)c(C)c3)c3C(=O)N(CCCn3c12)c1cn(C)c2ccc(cc12)C(O)=O |(49.62,-43.13,;48.15,-42.65,;47.67,-41.19,;46.13,-41.2,;45.22,-39.95,;45.66,-42.66,;44.2,-43.14,;46.91,-43.56,;46.92,-45.11,;45.59,-45.88,;44.26,-45.11,;45.59,-47.42,;46.92,-48.2,;48.25,-47.43,;49.73,-47.9,;50.21,-49.37,;51.71,-49.69,;52.19,-51.15,;53.7,-51.47,;54.17,-52.94,;55.67,-53.25,;56.15,-54.71,;57.66,-55.02,;55.12,-55.86,;55.6,-57.33,;53.61,-55.54,;52.58,-56.69,;53.14,-54.08,;50.64,-46.65,;52.2,-46.71,;52.81,-48.12,;53.22,-45.53,;52.93,-44,;51.56,-43.27,;50.14,-43.89,;49.73,-45.39,;48.25,-45.87,;54.7,-45.93,;55.91,-44.96,;57.2,-45.8,;58.64,-45.25,;56.8,-47.29,;57.63,-48.57,;56.94,-49.93,;55.4,-50.02,;54.56,-48.73,;55.26,-47.36,;56.15,-51.34,;57.69,-51.34,;54.95,-52.29,)| Show InChI InChI=1S/C39H39Cl2N5O4/c1-21-17-26(18-22(2)35(21)41)50-16-7-9-27-28-11-12-30(40)34(33-23(3)42-44(6)24(33)4)36(28)46-15-8-14-45(38(47)37(27)46)32-20-43(5)31-13-10-25(39(48)49)19-29(31)32/h10-13,17-20H,7-9,14-16H2,1-6H3,(H,48,49) | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 0.0890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-Bak-BH3 binding to MBP-fused MCL1 (172 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 CodonPlus (DE3) RIL af... |
J Med Chem 61: 2410-2421 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01155
BindingDB Entry DOI: 10.7270/Q2125W3M |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50244166
(CHEMBL4067929 | US11596639, Example 80)Show SMILES Cc1nn(C)c(C)c1-c1c(Cl)ccc2c(CCCOc3cc(C)c(Cl)c(C)c3)c3C(=O)N(CCCn3c12)c1cn(C)c2ccc(cc12)C(O)=O |(49.62,-43.13,;48.15,-42.65,;47.67,-41.19,;46.13,-41.2,;45.22,-39.95,;45.66,-42.66,;44.2,-43.14,;46.91,-43.56,;46.92,-45.11,;45.59,-45.88,;44.26,-45.11,;45.59,-47.42,;46.92,-48.2,;48.25,-47.43,;49.73,-47.9,;50.21,-49.37,;51.71,-49.69,;52.19,-51.15,;53.7,-51.47,;54.17,-52.94,;55.67,-53.25,;56.15,-54.71,;57.66,-55.02,;55.12,-55.86,;55.6,-57.33,;53.61,-55.54,;52.58,-56.69,;53.14,-54.08,;50.64,-46.65,;52.2,-46.71,;52.81,-48.12,;53.22,-45.53,;52.93,-44,;51.56,-43.27,;50.14,-43.89,;49.73,-45.39,;48.25,-45.87,;54.7,-45.93,;55.91,-44.96,;57.2,-45.8,;58.64,-45.25,;56.8,-47.29,;57.63,-48.57,;56.94,-49.93,;55.4,-50.02,;54.56,-48.73,;55.26,-47.36,;56.15,-51.34,;57.69,-51.34,;54.95,-52.29,)| Show InChI InChI=1S/C39H39Cl2N5O4/c1-21-17-26(18-22(2)35(21)41)50-16-7-9-27-28-11-12-30(40)34(33-23(3)42-44(6)24(33)4)36(28)46-15-8-14-45(38(47)37(27)46)32-20-43(5)31-13-10-25(39(48)49)19-29(31)32/h10-13,17-20H,7-9,14-16H2,1-6H3,(H,48,49) | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 0.0890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-Bak-BH3 binding to MBP-fused MCL1 (172 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 CodonPlus (DE3) RIL af... |
J Med Chem 61: 2410-2421 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01155
BindingDB Entry DOI: 10.7270/Q2125W3M |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50244166
(CHEMBL4067929 | US11596639, Example 80)Show SMILES Cc1nn(C)c(C)c1-c1c(Cl)ccc2c(CCCOc3cc(C)c(Cl)c(C)c3)c3C(=O)N(CCCn3c12)c1cn(C)c2ccc(cc12)C(O)=O |(49.62,-43.13,;48.15,-42.65,;47.67,-41.19,;46.13,-41.2,;45.22,-39.95,;45.66,-42.66,;44.2,-43.14,;46.91,-43.56,;46.92,-45.11,;45.59,-45.88,;44.26,-45.11,;45.59,-47.42,;46.92,-48.2,;48.25,-47.43,;49.73,-47.9,;50.21,-49.37,;51.71,-49.69,;52.19,-51.15,;53.7,-51.47,;54.17,-52.94,;55.67,-53.25,;56.15,-54.71,;57.66,-55.02,;55.12,-55.86,;55.6,-57.33,;53.61,-55.54,;52.58,-56.69,;53.14,-54.08,;50.64,-46.65,;52.2,-46.71,;52.81,-48.12,;53.22,-45.53,;52.93,-44,;51.56,-43.27,;50.14,-43.89,;49.73,-45.39,;48.25,-45.87,;54.7,-45.93,;55.91,-44.96,;57.2,-45.8,;58.64,-45.25,;56.8,-47.29,;57.63,-48.57,;56.94,-49.93,;55.4,-50.02,;54.56,-48.73,;55.26,-47.36,;56.15,-51.34,;57.69,-51.34,;54.95,-52.29,)| Show InChI InChI=1S/C39H39Cl2N5O4/c1-21-17-26(18-22(2)35(21)41)50-16-7-9-27-28-11-12-30(40)34(33-23(3)42-44(6)24(33)4)36(28)46-15-8-14-45(38(47)37(27)46)32-20-43(5)31-13-10-25(39(48)49)19-29(31)32/h10-13,17-20H,7-9,14-16H2,1-6H3,(H,48,49) | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 0.0890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-Bak-BH3 binding to MBP-fused MCL1 (172 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 CodonPlus (DE3) RIL af... |
J Med Chem 61: 2410-2421 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01155
BindingDB Entry DOI: 10.7270/Q2125W3M |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM597071
(US11596639, Example 670)Show SMILES C[C@@H]1CN(c2cn(C)c3ccc(cc23)-c2ncn(n2)-c2nccc(C)n2)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(-.81,3.26,;-.81,1.72,;.72,1.88,;1.63,.64,;3.16,.8,;4.22,-.32,;5.61,.34,;6.94,-.43,;5.41,1.87,;6.41,3.04,;5.9,4.49,;4.38,4.77,;3.38,3.6,;3.9,2.15,;3.87,6.23,;4.77,7.47,;3.87,8.72,;2.4,8.24,;2.4,6.7,;1.16,9.15,;1.32,10.68,;.07,11.58,;-1.33,10.96,;-1.49,9.43,;-2.9,8.8,;-.25,8.52,;1,-.77,;1.9,-2.02,;-.53,-.93,;-1.43,-2.18,;-.96,-3.64,;.54,-3.97,;1.03,-5.43,;2.53,-5.76,;3.02,-7.22,;4.54,-7.49,;5.06,-8.94,;6.57,-9.26,;4.07,-10.12,;4.55,-11.58,;2.56,-9.85,;1.59,-11.05,;2.03,-8.4,;-2.9,-1.7,;-4.23,-2.47,;-5.57,-1.7,;-5.57,-.16,;-6.94,.55,;-4.23,.61,;-4.23,2.15,;-5.48,3.05,;-6.94,2.58,;-5,4.52,;-3.46,4.52,;-2.69,5.85,;-2.99,3.05,;-1.52,2.58,;-2.9,-.16,;-1.43,.31,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM597078
(US11596639, Example 677)Show SMILES COCCn1c(cc2cc(COC)cc(N3C[C@@H](C)n4c(c(CCCOc5cc(C)c(Cl)c(C)c5)c5ccc(Cl)c(-c6c(C)nn(C)c6C)c45)C3=O)c12)C(O)=O |r,wD:17.17,(-.95,9.3,;-.44,7.85,;1.08,7.57,;1.59,6.12,;3.1,5.84,;4.22,6.89,;5.58,6.16,;5.29,4.65,;6.23,3.42,;5.64,2,;6.58,.78,;5.99,-.64,;6.93,-1.87,;4.11,1.8,;3.18,3.02,;1.65,2.86,;.74,4.11,;-.79,3.95,;-.79,5.49,;-1.42,2.54,;-.51,1.29,;-1.42,.05,;-.94,-1.42,;.56,-1.75,;1.05,-3.21,;2.55,-3.54,;3.04,-5,;4.56,-5.27,;5.08,-6.71,;6.59,-7.03,;4.09,-7.89,;4.56,-9.36,;2.57,-7.62,;1.61,-8.82,;2.05,-6.18,;-2.88,.52,;-4.22,-.25,;-5.55,.52,;-5.55,2.06,;-6.92,2.77,;-4.22,2.83,;-4.22,4.37,;-5.46,5.28,;-6.93,4.8,;-4.99,6.74,;-3.45,6.74,;-2.68,8.08,;-2.97,5.28,;-1.5,4.8,;-2.88,2.06,;1.02,1.45,;1.91,.2,;3.77,4.44,;4.02,8.42,;5.24,9.36,;2.6,9.01,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596923
(US11596639, Example 520)Show SMILES COc1ccc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)ncnc5C)c34)C2=O)c2n(Cc3cc(C)ccn3)c(cc12)C(O)=O |r,wD:8.8,(7.8,1.13,;6.9,2.39,;5.37,2.24,;4.73,.84,;3.2,.69,;2.3,1.94,;.77,1.8,;-.14,3.04,;-1.67,2.88,;-1.67,4.42,;-2.29,1.47,;-1.39,.23,;-2.29,-1.02,;-1.82,-2.48,;-.32,-2.81,;.17,-4.27,;1.67,-4.6,;2.16,-6.06,;3.68,-6.33,;4.2,-7.78,;5.71,-8.1,;3.21,-8.96,;3.69,-10.42,;1.7,-8.69,;.73,-9.89,;1.17,-7.24,;-3.76,-.54,;-5.09,-1.31,;-6.43,-.54,;-6.43,1,;-7.8,1.71,;-5.09,1.77,;-5.09,3.31,;-3.76,4.08,;-2.43,3.31,;-3.76,5.62,;-5.09,6.39,;-6.43,5.62,;-6.43,4.08,;-7.76,3.31,;-3.76,1,;.14,.39,;1.04,-.86,;2.94,3.34,;2.32,4.76,;.82,5.09,;.05,6.42,;.82,7.76,;.05,9.09,;.82,10.42,;-1.49,9.09,;-2.26,7.76,;-1.49,6.42,;3.48,5.78,;4.8,5,;4.47,3.49,;3.33,7.31,;4.58,8.2,;1.93,7.95,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596924
(US11596639, Example 521)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(OC2CCN(C)C2)cc2cc(C(O)=O)n(C)c12 |r,wD:1.0,(-3.04,5.53,;-3.04,3.99,;-1.5,4.15,;-.6,2.91,;-1.23,1.5,;-.33,.25,;-2.76,1.34,;-3.66,.09,;-3.19,-1.37,;-1.69,-1.7,;-1.2,-3.16,;.31,-3.49,;.79,-4.95,;2.31,-5.22,;2.84,-6.67,;4.34,-6.99,;1.84,-7.85,;2.32,-9.31,;.33,-7.58,;-.64,-8.78,;-.2,-6.13,;-5.13,.57,;-6.46,-.2,;-7.79,.57,;-7.79,2.11,;-9.16,2.81,;-6.46,2.88,;-6.46,4.42,;-7.71,5.32,;-9.15,4.79,;-7.23,6.79,;-5.69,6.79,;-4.75,8.01,;-5.22,5.32,;-3.73,4.91,;-5.13,2.11,;-3.66,2.58,;.93,3.05,;1.83,1.8,;3.36,1.95,;4.26,.69,;5.79,.84,;6.84,-.28,;8.24,.38,;8.04,1.91,;9.16,2.96,;6.53,2.19,;4,3.35,;3.1,4.6,;3.44,6.11,;2.11,6.89,;1.96,8.42,;3.21,9.31,;.56,9.06,;.96,5.87,;-.55,6.2,;1.57,4.45,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596929
(US11596639, Example 526)Show SMILES C[C@@H]1CN(c2cn(CCN3CCN(C)CC3)c3ccc(cc23)-c2ncn(C)n2)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(-3.48,3.96,;-3.48,2.42,;-1.94,2.58,;-1.04,1.34,;.49,1.5,;1.55,.38,;2.94,1.04,;4.28,.27,;4.28,-1.27,;5.61,-2.04,;5.61,-3.58,;6.94,-4.35,;8.28,-3.58,;9.61,-4.35,;8.28,-2.04,;6.94,-1.27,;2.74,2.57,;3.74,3.74,;3.23,5.19,;1.71,5.47,;.71,4.3,;1.23,2.85,;1.2,6.93,;-.26,7.4,;-.26,8.94,;1.2,9.42,;1.68,10.88,;2.11,8.17,;-1.67,-.07,;-.77,-1.32,;-3.2,-.23,;-4.1,-1.48,;-3.63,-2.94,;-2.12,-3.27,;-1.64,-4.73,;-.13,-5.06,;.35,-6.52,;1.87,-6.79,;2.4,-8.24,;3.9,-8.56,;1.41,-9.42,;1.88,-10.88,;-.11,-9.15,;-1.08,-10.35,;-.64,-7.7,;-5.57,-1,;-6.9,-1.77,;-8.23,-1,;-8.23,.54,;-9.6,1.25,;-6.9,1.31,;-6.9,2.85,;-5.65,3.75,;-4.19,3.28,;-6.13,5.22,;-7.67,5.22,;-8.44,6.55,;-8.15,3.75,;-9.61,3.28,;-5.57,.54,;-4.1,1.02,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596931
(US11596639, Example 528)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(C)cc2cc(C(O)=O)n(Cc3cccc(n3)N3CCN(CC3)C(C)=O)c12 |r,wD:1.0,(-.63,1.75,;-.63,.21,;.91,.38,;1.81,-.87,;1.18,-2.28,;2.08,-3.53,;-.35,-2.44,;-1.25,-3.68,;-.78,-5.15,;.73,-5.48,;1.21,-6.94,;2.72,-7.27,;3.2,-8.73,;4.72,-9,;5.25,-10.45,;6.75,-10.77,;4.26,-11.63,;4.73,-13.09,;2.74,-11.36,;1.77,-12.55,;2.21,-9.91,;-2.72,-3.21,;-4.05,-3.98,;-5.38,-3.21,;-5.38,-1.67,;-6.75,-.96,;-4.05,-.9,;-4.05,.64,;-5.3,1.55,;-6.74,1.02,;-4.82,3.01,;-3.28,3.01,;-2.34,4.23,;-2.8,1.55,;-1.32,1.13,;-2.72,-1.67,;-1.25,-1.19,;3.34,-.72,;4.24,-1.98,;5.77,-1.83,;6.67,-3.08,;6.41,-.43,;5.52,.83,;5.85,2.33,;4.52,3.11,;4.37,4.64,;5.63,5.54,;2.97,5.28,;3.37,2.09,;1.86,2.42,;1.09,3.75,;-.45,3.75,;-1.22,5.09,;-.45,6.42,;1.09,6.42,;1.86,5.09,;1.86,7.76,;3.4,7.76,;4.17,9.09,;3.4,10.42,;1.86,10.42,;1.09,9.09,;4.17,11.76,;5.71,11.76,;3.4,13.09,;3.98,.68,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596932
(US11596639, Example 529)Show SMILES C[C@@H]1CN(c2cn(CCCl)c3ccc(cc23)-c2ncn(C)n2)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(-1.48,3.96,;-1.48,2.42,;.06,2.58,;.96,1.34,;2.49,1.5,;3.55,.38,;4.94,1.04,;6.28,.27,;6.28,-1.27,;7.61,-2.04,;4.74,2.57,;5.74,3.74,;5.23,5.19,;3.72,5.47,;2.71,4.3,;3.23,2.85,;3.2,6.93,;1.74,7.4,;1.74,8.94,;3.2,9.42,;3.68,10.88,;4.11,8.17,;.34,-.07,;1.23,-1.32,;-1.2,-.23,;-2.1,-1.48,;-1.63,-2.94,;-.12,-3.27,;.36,-4.73,;1.87,-5.06,;2.35,-6.52,;3.87,-6.79,;4.4,-8.24,;5.9,-8.56,;3.41,-9.42,;3.88,-10.88,;1.89,-9.15,;.92,-10.35,;1.36,-7.7,;-3.57,-1,;-4.9,-1.77,;-6.23,-1,;-6.23,.54,;-7.6,1.25,;-4.9,1.31,;-4.9,2.85,;-3.65,3.75,;-2.19,3.28,;-4.13,5.22,;-5.67,5.22,;-6.44,6.55,;-6.15,3.75,;-7.61,3.28,;-3.57,.54,;-2.1,1.02,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596933
(US11596639, Example 530)Show SMILES COCCn1cnc(n1)-c1ccc2n(C)cc(N3C[C@@H](C)n4c(c(CCCOc5cc(C)c(Cl)c(C)c5)c5ccc(Cl)c(-c6c(C)nn(C)c6C)c45)C3=O)c2c1 |r,wD:19.20,(2.76,12.76,;3.79,11.61,;3.31,10.15,;4.34,9.01,;3.87,7.54,;2.4,7.06,;2.4,5.52,;3.87,5.05,;4.77,6.29,;4.38,3.6,;5.9,3.32,;6.41,1.86,;5.41,.69,;5.61,-.83,;6.94,-1.6,;4.22,-1.5,;3.16,-.38,;1.63,-.54,;.72,.71,;-.81,.55,;-.81,2.09,;-1.43,-.86,;-.53,-2.11,;-1.43,-3.35,;-.96,-4.82,;.54,-5.15,;1.03,-6.61,;2.53,-6.94,;3.02,-8.4,;4.54,-8.67,;5.06,-10.11,;6.57,-10.43,;4.07,-11.29,;4.55,-12.76,;2.56,-11.03,;1.59,-12.22,;2.03,-9.58,;-2.9,-2.88,;-4.23,-3.65,;-5.57,-2.88,;-5.57,-1.34,;-6.94,-.63,;-4.23,-.57,;-4.23,.97,;-2.99,1.88,;-1.52,1.4,;-3.46,3.34,;-5,3.34,;-5.77,4.68,;-5.48,1.88,;-6.94,1.4,;-2.9,-1.34,;1,-1.95,;1.9,-3.2,;3.9,.97,;3.38,2.43,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596935
(US11596639, Example 532)Show SMILES C[C@@H]1CN(c2cn(Cc3cscn3)c3ccc(cc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(-1.43,5.36,;-1.43,3.82,;.1,3.98,;1.01,2.73,;2.54,2.89,;3.6,1.77,;4.99,2.44,;6.32,1.67,;6.32,.13,;7.57,-.78,;7.09,-2.24,;5.55,-2.24,;5.07,-.78,;4.79,3.96,;5.79,5.13,;5.27,6.59,;3.76,6.87,;2.76,5.7,;3.27,4.24,;3.25,8.32,;1.73,8.6,;4.25,9.49,;.38,1.32,;1.27,.07,;-1.15,1.16,;-2.06,-.08,;-1.58,-1.55,;-.08,-1.88,;.41,-3.34,;1.91,-3.67,;2.4,-5.13,;3.91,-5.4,;4.44,-6.84,;5.95,-7.16,;3.45,-8.02,;3.92,-9.49,;1.93,-7.76,;.97,-8.95,;1.41,-6.31,;-3.52,.39,;-4.86,-.38,;-6.19,.39,;-6.19,1.93,;-7.56,2.64,;-4.86,2.7,;-4.86,4.24,;-3.61,5.15,;-2.15,4.67,;-4.09,6.61,;-5.63,6.61,;-6.4,7.95,;-6.1,5.15,;-7.57,4.67,;-3.52,1.93,;-2.06,2.41,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596937
(US11596639, Example 534)Show SMILES C[C@@H]1CN(c2cn(CC3CCN(C)C3)c3ccc(cc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(-1.58,5.36,;-1.58,3.82,;-.05,3.98,;.86,2.73,;2.39,2.89,;3.45,1.77,;4.84,2.44,;6.17,1.67,;6.17,.13,;4.93,-.78,;5.4,-2.24,;6.94,-2.24,;7.71,-3.58,;7.42,-.78,;4.64,3.96,;5.64,5.13,;5.13,6.59,;3.61,6.87,;2.61,5.7,;3.13,4.24,;3.1,8.32,;1.58,8.6,;4.1,9.49,;.23,1.32,;1.13,.07,;-1.3,1.16,;-2.2,-.08,;-1.73,-1.55,;-.23,-1.88,;.26,-3.34,;1.76,-3.67,;2.25,-5.13,;3.77,-5.4,;4.29,-6.84,;5.8,-7.16,;3.3,-8.02,;3.78,-9.49,;1.79,-7.76,;.82,-8.95,;1.26,-6.31,;-3.67,.39,;-5,-.38,;-6.34,.39,;-6.34,1.93,;-7.71,2.64,;-5,2.7,;-5,4.24,;-3.76,5.15,;-2.29,4.67,;-4.23,6.61,;-5.77,6.61,;-6.54,7.95,;-6.25,5.15,;-7.71,4.67,;-3.67,1.93,;-2.2,2.41,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596938
(US11596639, Example 535)Show SMILES COc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)ncnc5C)c34)C2=O)c2n(C)c(cc2c1)C(O)=O |r,wD:7.7,(6.03,-.71,;6.67,.69,;5.77,1.95,;4.24,1.8,;3.34,3.05,;1.81,2.91,;.91,4.15,;-.63,3.99,;-.63,5.53,;-1.25,2.58,;-.35,1.34,;-1.25,.09,;-.78,-1.37,;.73,-1.7,;1.21,-3.16,;2.72,-3.49,;3.2,-4.95,;4.72,-5.22,;5.25,-6.67,;6.75,-6.99,;4.26,-7.85,;4.73,-9.31,;2.74,-7.58,;1.77,-8.78,;2.21,-6.13,;-2.72,.57,;-4.05,-.2,;-5.38,.57,;-5.38,2.11,;-6.75,2.81,;-4.05,2.88,;-4.05,4.42,;-5.38,5.19,;-6.72,4.42,;-5.38,6.73,;-4.05,7.5,;-2.72,6.73,;-2.72,5.19,;-1.38,4.42,;-2.72,2.11,;1.18,1.5,;2.08,.25,;3.98,4.45,;3.37,5.87,;1.86,6.2,;4.52,6.89,;5.85,6.11,;5.51,4.6,;6.41,3.35,;4.37,8.42,;5.63,9.31,;2.97,9.06,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596939
(US11596639, Example 536)Show SMILES COc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)nn(C)c5C)c34)C2=O)c2n(Cc3cccc(C)n3)c(cc2c1)C(O)=O |r,wD:7.7,(6.03,-1.15,;6.67,.25,;5.78,1.5,;4.24,1.36,;3.35,2.61,;1.82,2.46,;.91,3.71,;-.62,3.55,;-.62,5.09,;-1.25,2.14,;-.34,.9,;-1.25,-.35,;-.78,-1.82,;.73,-2.15,;1.22,-3.61,;2.72,-3.94,;3.21,-5.4,;4.72,-5.66,;5.25,-7.11,;6.76,-7.43,;4.26,-8.29,;4.73,-9.76,;2.74,-8.02,;1.78,-9.22,;2.22,-6.58,;-2.71,.13,;-4.05,-.64,;-5.38,.13,;-5.38,1.67,;-6.75,2.37,;-4.05,2.44,;-4.05,3.98,;-2.8,4.88,;-1.34,4.4,;-3.28,6.35,;-4.82,6.35,;-5.59,7.68,;-5.29,4.88,;-6.76,4.4,;-2.71,1.67,;1.19,1.06,;2.08,-.2,;3.99,4.01,;3.37,5.42,;1.87,5.76,;1.1,7.09,;1.87,8.42,;1.1,9.76,;-.44,9.76,;-1.21,8.42,;-2.75,8.42,;-.44,7.09,;4.52,6.44,;5.85,5.66,;5.52,4.16,;6.41,2.91,;4.38,7.98,;5.63,8.87,;2.97,8.61,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596940
(US11596639, Example 537)Show SMILES COCCOc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)nn(C)c5C)c34)C2=O)c2n(Cc3ccccn3)c(cc2c1)C(O)=O |r,wD:10.10,(6.97,-5.06,;6.08,-3.81,;6.71,-2.4,;5.82,-1.15,;6.46,.25,;5.56,1.5,;4.03,1.36,;3.13,2.61,;1.6,2.46,;.7,3.71,;-.84,3.55,;-.84,5.09,;-1.46,2.14,;-.56,.9,;-1.46,-.35,;-.99,-1.82,;.52,-2.15,;1,-3.61,;2.51,-3.94,;2.99,-5.4,;4.51,-5.66,;5.04,-7.11,;6.54,-7.43,;4.05,-8.29,;4.52,-9.76,;2.53,-8.02,;1.56,-9.22,;2,-6.58,;-2.93,.13,;-4.26,-.64,;-5.59,.13,;-5.59,1.67,;-6.96,2.37,;-4.26,2.44,;-4.26,3.98,;-3.01,4.88,;-1.55,4.4,;-3.49,6.35,;-5.03,6.35,;-5.8,7.68,;-5.51,4.88,;-6.97,4.4,;-2.93,1.67,;.97,1.06,;1.87,-.2,;3.77,4.01,;3.16,5.42,;1.65,5.76,;.88,7.09,;1.65,8.42,;.88,9.76,;-.66,9.76,;-1.43,8.42,;-.66,7.09,;4.31,6.44,;5.64,5.66,;5.31,4.16,;6.2,2.91,;4.16,7.98,;5.42,8.87,;2.76,8.61,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596941
(US11596639, Example 538)Show SMILES COc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)nn(C)c5C)c34)C2=O)c2n(Cc3ccccn3)c(cc2c1)C(O)=O |r,wD:7.7,(6.03,-1.15,;6.67,.25,;5.78,1.5,;4.24,1.36,;3.35,2.61,;1.82,2.46,;.91,3.71,;-.62,3.55,;-.62,5.09,;-1.25,2.14,;-.34,.9,;-1.25,-.35,;-.78,-1.82,;.73,-2.15,;1.22,-3.61,;2.72,-3.94,;3.21,-5.4,;4.72,-5.66,;5.25,-7.11,;6.76,-7.43,;4.26,-8.29,;4.73,-9.76,;2.74,-8.02,;1.78,-9.22,;2.22,-6.58,;-2.71,.13,;-4.05,-.64,;-5.38,.13,;-5.38,1.67,;-6.75,2.37,;-4.05,2.44,;-4.05,3.98,;-2.8,4.88,;-1.34,4.4,;-3.28,6.35,;-4.82,6.35,;-5.59,7.68,;-5.29,4.88,;-6.76,4.4,;-2.71,1.67,;1.19,1.06,;2.08,-.2,;3.99,4.01,;3.37,5.42,;1.87,5.76,;1.1,7.09,;1.87,8.42,;1.1,9.76,;-.44,9.76,;-1.21,8.42,;-.44,7.09,;4.52,6.44,;5.85,5.66,;5.52,4.16,;6.41,2.91,;4.38,7.98,;5.63,8.87,;2.97,8.61,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596942
(US11596639, Example 539)Show SMILES COCCOc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)ncnc5C)c34)C2=O)c2n(C)c(cc2c1)C(O)=O |r,wD:10.10,(6.97,-4.62,;6.07,-3.36,;6.71,-1.96,;5.81,-.71,;6.45,.69,;5.56,1.95,;4.02,1.8,;3.13,3.05,;1.6,2.91,;.69,4.15,;-.84,3.99,;-.84,5.53,;-1.47,2.58,;-.56,1.34,;-1.47,.09,;-.99,-1.37,;.51,-1.7,;1,-3.16,;2.5,-3.49,;2.99,-4.95,;4.51,-5.22,;5.03,-6.67,;6.54,-6.99,;4.04,-7.85,;4.51,-9.31,;2.52,-7.58,;1.56,-8.78,;2,-6.13,;-2.93,.57,;-4.26,-.2,;-5.6,.57,;-5.6,2.11,;-6.97,2.81,;-4.26,2.88,;-4.26,4.42,;-5.6,5.19,;-6.93,4.42,;-5.6,6.73,;-4.26,7.5,;-2.93,6.73,;-2.93,5.19,;-1.6,4.42,;-2.93,2.11,;.97,1.5,;1.87,.25,;3.77,4.45,;3.15,5.87,;1.65,6.2,;4.31,6.89,;5.63,6.11,;5.3,4.6,;6.2,3.35,;4.16,8.42,;5.41,9.31,;2.76,9.06,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596943
(US11596639, Example 540)Show SMILES COCCOc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)nn(C)c5C)c34)C2=O)c2n(Cc3cccc(C)n3)c(cc2c1)C(O)=O |r,wD:10.10,(6.97,-5.06,;6.08,-3.81,;6.71,-2.4,;5.82,-1.15,;6.46,.25,;5.56,1.5,;4.03,1.36,;3.13,2.61,;1.6,2.46,;.7,3.71,;-.84,3.55,;-.84,5.09,;-1.46,2.14,;-.56,.9,;-1.46,-.35,;-.99,-1.82,;.52,-2.15,;1,-3.61,;2.51,-3.94,;2.99,-5.4,;4.51,-5.66,;5.04,-7.11,;6.54,-7.43,;4.05,-8.29,;4.52,-9.76,;2.53,-8.02,;1.56,-9.22,;2,-6.58,;-2.93,.13,;-4.26,-.64,;-5.59,.13,;-5.59,1.67,;-6.96,2.37,;-4.26,2.44,;-4.26,3.98,;-3.01,4.88,;-1.55,4.4,;-3.49,6.35,;-5.03,6.35,;-5.8,7.68,;-5.51,4.88,;-6.97,4.4,;-2.93,1.67,;.97,1.06,;1.87,-.2,;3.77,4.01,;3.16,5.42,;1.65,5.76,;.88,7.09,;1.65,8.42,;.88,9.76,;-.66,9.76,;-1.43,8.42,;-2.97,8.42,;-.66,7.09,;4.31,6.44,;5.64,5.66,;5.31,4.16,;6.2,2.91,;4.16,7.98,;5.42,8.87,;2.76,8.61,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596947
(US11596639, Example 544)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(CN2CCN(C)CC2)cc2cc(C(O)=O)n(C)c12 |r,wD:1.0,(-3.64,5.53,;-3.64,3.99,;-2.11,4.15,;-1.2,2.91,;-1.83,1.5,;-.93,.25,;-3.36,1.34,;-4.26,.09,;-3.79,-1.37,;-2.29,-1.7,;-1.8,-3.16,;-.29,-3.49,;.19,-4.95,;1.71,-5.22,;2.23,-6.67,;3.74,-6.99,;1.24,-7.85,;1.72,-9.31,;-.27,-7.58,;-1.24,-8.78,;-.8,-6.13,;-5.73,.57,;-7.06,-.2,;-8.4,.57,;-8.4,2.11,;-9.76,2.81,;-7.06,2.88,;-7.06,4.42,;-5.82,5.32,;-4.35,4.85,;-6.29,6.79,;-7.83,6.79,;-8.6,8.12,;-8.31,5.32,;-9.77,4.85,;-5.73,2.11,;-4.26,2.58,;.33,3.05,;1.23,1.8,;2.76,1.95,;3.66,.69,;5.19,.84,;6.12,-.39,;7.65,-.2,;8.24,1.22,;9.77,1.41,;7.32,2.45,;5.79,2.26,;3.4,3.35,;2.5,4.6,;2.84,6.11,;1.51,6.89,;1.36,8.42,;2.61,9.31,;-.04,9.06,;.36,5.87,;-1.15,6.2,;.97,4.45,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596955
(US11596639, Example 552)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(C)cc2cc(C(O)=O)n(Cc3cc(ccn3)N3CCN(CC3)C(C)=O)c12 |r,wD:1.0,(-.62,1.68,;-.62,.14,;.91,.3,;1.82,-.94,;1.19,-2.35,;2.08,-3.6,;-.34,-2.51,;-1.25,-3.75,;-.78,-5.22,;.73,-5.55,;1.22,-7.01,;2.72,-7.34,;3.21,-8.8,;4.72,-9.07,;5.25,-10.52,;6.76,-10.84,;4.26,-11.7,;4.73,-13.16,;2.74,-11.43,;1.78,-12.63,;2.22,-9.98,;-2.71,-3.28,;-4.05,-4.05,;-5.38,-3.28,;-5.38,-1.74,;-6.75,-1.03,;-4.05,-.97,;-4.05,.57,;-5.29,1.48,;-6.76,1,;-4.82,2.94,;-3.28,2.94,;-2.51,4.27,;-2.8,1.48,;-1.34,1,;-2.71,-1.74,;-1.25,-1.26,;3.35,-.8,;4.24,-2.05,;5.78,-1.9,;6.67,-3.15,;6.41,-.5,;5.52,.75,;5.85,2.26,;4.52,3.04,;4.38,4.57,;5.63,5.47,;2.97,5.21,;3.37,2.02,;1.87,2.35,;1.1,3.68,;1.87,5.02,;1.1,6.35,;-.44,6.35,;-1.21,5.02,;-.44,3.68,;1.87,7.69,;3.41,7.69,;4.22,9.01,;3.47,10.4,;1.85,10.45,;1.1,9.02,;4.28,11.71,;5.82,11.66,;3.55,13.06,;3.99,.61,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596956
(US11596639, Example 553)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(C)cc2cc(C(O)=O)n(Cc3cc(ccn3)N3CCNCC3)c12 |r,wD:1.0,(-.62,3.09,;-.62,1.55,;.91,1.71,;1.82,.46,;1.19,-.94,;2.08,-2.2,;-.34,-1.11,;-1.25,-2.35,;-.78,-3.82,;.73,-4.15,;1.22,-5.61,;2.72,-5.94,;3.21,-7.4,;4.72,-7.66,;5.25,-9.11,;6.76,-9.43,;4.26,-10.29,;4.73,-11.76,;2.74,-10.02,;1.78,-11.22,;2.22,-8.58,;-2.71,-1.87,;-4.05,-2.65,;-5.38,-1.87,;-5.38,-.33,;-6.75,.37,;-4.05,.43,;-4.05,1.97,;-5.29,2.88,;-6.76,2.4,;-4.82,4.34,;-3.28,4.34,;-2.51,5.68,;-2.8,2.88,;-1.34,2.4,;-2.71,-.33,;-1.25,.14,;3.35,.61,;4.24,-.64,;5.78,-.5,;6.67,-1.75,;6.41,.91,;5.52,2.16,;5.85,3.66,;4.52,4.44,;4.38,5.98,;5.63,6.87,;2.97,6.61,;3.37,3.42,;1.87,3.75,;1.1,5.09,;1.87,6.42,;1.1,7.76,;-.44,7.76,;-1.21,6.42,;-.44,5.09,;1.87,9.09,;3.41,9.09,;4.18,10.42,;3.41,11.76,;1.87,11.76,;1.1,10.42,;3.99,2.01,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596959
(US11596639, Example 556)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(C)cc2cc(C(O)=O)n(Cc3cc(ccn3)C#N)c12 |r,wD:1.0,(-.62,3.75,;-.62,2.21,;.91,2.38,;1.82,1.13,;1.19,-.28,;2.08,-1.53,;-.34,-.44,;-1.25,-1.68,;-.78,-3.15,;.73,-3.48,;1.22,-4.94,;2.72,-5.27,;3.21,-6.73,;4.72,-7,;5.25,-8.45,;6.76,-8.76,;4.26,-9.62,;4.73,-11.09,;2.74,-9.36,;1.78,-10.55,;2.22,-7.91,;-2.71,-1.21,;-4.05,-1.98,;-5.38,-1.21,;-5.38,.33,;-6.75,1.04,;-4.05,1.1,;-4.05,2.64,;-5.29,3.55,;-6.76,3.07,;-4.82,5.01,;-3.28,5.01,;-2.51,6.35,;-2.8,3.55,;-1.34,3.07,;-2.71,.33,;-1.25,.81,;3.35,1.28,;4.24,.02,;5.78,.17,;6.67,-1.08,;6.41,1.57,;5.52,2.83,;5.85,4.33,;4.52,5.11,;4.38,6.64,;5.63,7.54,;2.97,7.28,;3.37,4.09,;1.87,4.42,;1.1,5.76,;1.87,7.09,;1.18,8.49,;-.44,8.42,;-1.21,7.09,;-.44,5.76,;1.96,9.81,;2.75,11.13,;3.99,2.68,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596960
(US11596639, Example 557)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(C)cc2cc(C(O)=O)n(Cc3cccc(n3)C#N)c12 |r,wD:1.0,(-.62,3.75,;-.62,2.21,;.91,2.38,;1.82,1.13,;1.19,-.28,;2.08,-1.53,;-.34,-.44,;-1.25,-1.68,;-.78,-3.15,;.73,-3.48,;1.22,-4.94,;2.72,-5.27,;3.21,-6.73,;4.72,-7,;5.25,-8.45,;6.76,-8.76,;4.26,-9.62,;4.73,-11.09,;2.74,-9.36,;1.78,-10.55,;2.22,-7.91,;-2.71,-1.21,;-4.05,-1.98,;-5.38,-1.21,;-5.38,.33,;-6.75,1.04,;-4.05,1.1,;-4.05,2.64,;-5.29,3.55,;-6.76,3.07,;-4.82,5.01,;-3.28,5.01,;-2.51,6.35,;-2.8,3.55,;-1.34,3.07,;-2.71,.33,;-1.25,.81,;3.35,1.28,;4.24,.02,;5.78,.17,;6.67,-1.08,;6.41,1.57,;5.52,2.83,;5.85,4.33,;4.52,5.11,;4.38,6.64,;5.63,7.54,;2.97,7.28,;3.37,4.09,;1.87,4.42,;1.1,5.76,;-.44,5.76,;-1.21,7.09,;-.44,8.42,;1.18,8.49,;1.87,7.09,;1.96,9.81,;2.75,11.13,;3.99,2.68,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596961
(US11596639, Example 558)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)ncnc4C)c3n12)c1cc(OCCN2CCOCC2)cc2cc(C(O)=O)n(C)c12 |r,wD:1.0,(-3.01,5.53,;-3.01,3.99,;-1.47,4.15,;-.57,2.91,;-1.2,1.5,;-.3,.25,;-2.73,1.34,;-3.63,.09,;-3.16,-1.37,;-1.65,-1.7,;-1.17,-3.16,;.34,-3.49,;.82,-4.95,;2.34,-5.22,;2.87,-6.67,;4.37,-6.99,;1.88,-7.85,;2.35,-9.31,;.36,-7.58,;-.61,-8.78,;-.17,-6.13,;-5.1,.57,;-6.43,-.2,;-7.76,.57,;-7.76,2.11,;-9.13,2.81,;-6.43,2.88,;-6.43,4.42,;-5.1,5.19,;-3.76,4.42,;-5.1,6.73,;-6.43,7.5,;-7.76,6.73,;-7.76,5.19,;-9.1,4.42,;-5.1,2.11,;-3.63,2.58,;.96,3.05,;1.86,1.8,;3.39,1.95,;4.29,.69,;3.65,-.71,;4.54,-1.96,;6.08,-1.81,;7.01,-3.04,;8.53,-2.85,;9.13,-1.43,;8.2,-.2,;6.68,-.39,;4.03,3.35,;3.13,4.6,;3.47,6.11,;2.14,6.89,;1.99,8.42,;3.25,9.31,;.59,9.06,;.99,5.87,;-.52,6.2,;1.6,4.45,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596962
(US11596639, Example 559)Show SMILES COCCn1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)nc(CN6CCN(C)CC6)nc5C)c34)C2=O)c2cc(ccc12)C(O)=O |r,wD:9.9,(8.92,-3.41,;8.92,-1.87,;7.59,-1.1,;7.59,.44,;6.26,1.21,;4.86,.55,;3.81,1.66,;2.27,1.5,;1.37,2.75,;-.16,2.59,;-.16,4.13,;-.79,1.18,;.12,-.06,;-.79,-1.31,;-.32,-2.78,;1.19,-3.1,;1.67,-4.57,;3.18,-4.89,;3.67,-6.36,;5.18,-6.62,;5.71,-8.07,;7.22,-8.39,;4.72,-9.25,;5.19,-10.72,;3.2,-8.98,;2.23,-10.18,;2.68,-7.53,;-2.25,-.83,;-3.59,-1.6,;-4.92,-.83,;-4.92,.71,;-6.29,1.41,;-3.59,1.48,;-3.59,3.02,;-2.25,3.79,;-.92,3.02,;-2.25,5.33,;-3.59,6.1,;-3.59,7.64,;-4.92,8.41,;-4.92,9.95,;-6.26,10.72,;-7.59,9.95,;-8.92,10.72,;-7.59,8.41,;-6.26,7.64,;-4.92,5.33,;-4.92,3.79,;-6.26,3.02,;-2.25,.71,;1.65,.1,;2.54,-1.16,;4.54,3.02,;4.03,4.47,;5.03,5.64,;6.54,5.36,;7.06,3.91,;6.05,2.74,;4.51,7.09,;3,7.37,;5.51,8.26,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596964
(US11596639, Example 561)Show SMILES C[C@@H]1CN(c2cn(Cc3ccccn3)c3ccc(cc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(-1.48,5.36,;-1.48,3.82,;.06,3.98,;.96,2.73,;2.49,2.89,;3.55,1.77,;4.94,2.44,;6.28,1.67,;6.28,.13,;7.61,-.64,;7.61,-2.18,;6.28,-2.95,;4.94,-2.18,;4.94,-.64,;4.74,3.96,;5.74,5.13,;5.23,6.59,;3.72,6.87,;2.71,5.7,;3.23,4.24,;3.2,8.32,;1.69,8.6,;4.2,9.49,;.34,1.32,;1.23,.07,;-1.2,1.16,;-2.1,-.08,;-1.63,-1.55,;-.12,-1.88,;.36,-3.34,;1.87,-3.67,;2.35,-5.13,;3.87,-5.4,;4.4,-6.84,;5.9,-7.16,;3.41,-8.02,;3.88,-9.49,;1.89,-7.76,;.92,-8.95,;1.36,-6.31,;-3.57,.39,;-4.9,-.38,;-6.23,.39,;-6.23,1.93,;-7.6,2.64,;-4.9,2.7,;-4.9,4.24,;-6.15,5.15,;-7.61,4.67,;-5.67,6.61,;-4.13,6.61,;-3.36,7.95,;-3.65,5.15,;-2.19,4.67,;-3.57,1.93,;-2.1,2.41,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596966
(US11596639, Example 563)Show SMILES C[C@@H]1CN(c2cn(Cc3cccnc3)c3ccc(cc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(-1.48,5.36,;-1.48,3.82,;.06,3.98,;.96,2.73,;2.49,2.89,;3.55,1.77,;4.94,2.44,;6.28,1.67,;6.28,.13,;4.94,-.64,;4.94,-2.18,;6.28,-2.95,;7.61,-2.18,;7.61,-.64,;4.74,3.96,;5.74,5.13,;5.23,6.59,;3.72,6.87,;2.71,5.7,;3.23,4.24,;3.2,8.32,;1.69,8.6,;4.2,9.49,;.34,1.32,;1.23,.07,;-1.2,1.16,;-2.1,-.08,;-1.63,-1.55,;-.12,-1.88,;.36,-3.34,;1.87,-3.67,;2.35,-5.13,;3.87,-5.4,;4.4,-6.84,;5.9,-7.16,;3.41,-8.02,;3.88,-9.49,;1.89,-7.76,;.92,-8.95,;1.36,-6.31,;-3.57,.39,;-4.9,-.38,;-6.23,.39,;-6.23,1.93,;-7.6,2.64,;-4.9,2.7,;-4.9,4.24,;-6.15,5.15,;-7.61,4.67,;-5.67,6.61,;-4.13,6.61,;-3.36,7.95,;-3.65,5.15,;-2.19,4.67,;-3.57,1.93,;-2.1,2.41,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596968
(US11596639, Example 565)Show SMILES COc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)ncnc5C)c34)C2=O)c2n(Cc3cc(C)ccn3)c(cc2c1)C(O)=O |r,wD:7.7,(6.03,-1.82,;6.67,-.42,;5.77,.84,;4.24,.69,;3.34,1.94,;1.81,1.8,;.91,3.04,;-.63,2.88,;-.63,4.42,;-1.25,1.47,;-.35,.23,;-1.25,-1.02,;-.78,-2.48,;.73,-2.81,;1.21,-4.27,;2.72,-4.6,;3.2,-6.06,;4.72,-6.33,;5.25,-7.78,;6.75,-8.1,;4.26,-8.96,;4.73,-10.42,;2.74,-8.69,;1.77,-9.89,;2.21,-7.24,;-2.72,-.54,;-4.05,-1.31,;-5.38,-.54,;-5.38,1,;-6.75,1.71,;-4.05,1.77,;-4.05,3.31,;-2.72,4.08,;-1.38,3.31,;-2.72,5.62,;-4.05,6.39,;-5.38,5.62,;-5.38,4.08,;-6.72,3.31,;-2.72,1,;1.18,.39,;2.08,-.86,;3.98,3.34,;3.37,4.76,;1.86,5.09,;1.09,6.42,;1.86,7.76,;1.09,9.09,;1.86,10.42,;-.45,9.09,;-1.22,7.76,;-.45,6.42,;4.52,5.78,;5.85,5,;5.51,3.49,;6.41,2.24,;4.37,7.31,;5.63,8.2,;2.97,7.95,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596969
(US11596639, Example 566)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)ncnc4C)c3n12)c1cc(OCCN(C)C)cc2cc(C(O)=O)n(Cc3cccc(C)n3)c12 |r,wD:1.0,(-.84,4.42,;-.84,2.88,;.69,3.04,;1.6,1.8,;.97,.39,;1.87,-.86,;-.56,.23,;-1.47,-1.02,;-.99,-2.48,;.51,-2.81,;1,-4.27,;2.5,-4.6,;2.99,-6.06,;4.51,-6.33,;5.03,-7.78,;6.54,-8.1,;4.04,-8.96,;4.51,-10.42,;2.52,-8.69,;1.56,-9.89,;2,-7.24,;-2.93,-.54,;-4.26,-1.31,;-5.6,-.54,;-5.6,1,;-6.97,1.71,;-4.26,1.77,;-4.26,3.31,;-2.93,4.08,;-1.6,3.31,;-2.93,5.62,;-4.26,6.39,;-5.6,5.62,;-5.6,4.08,;-6.93,3.31,;-2.93,1,;-1.47,1.47,;3.13,1.94,;4.02,.69,;5.56,.84,;6.45,-.42,;5.81,-1.82,;6.71,-3.07,;6.07,-4.47,;4.54,-4.62,;6.97,-5.73,;6.2,2.24,;5.3,3.49,;5.63,5,;4.31,5.78,;4.16,7.31,;5.41,8.2,;2.76,7.95,;3.15,4.76,;1.65,5.09,;.88,6.42,;-.66,6.42,;-1.43,7.76,;-.66,9.09,;.88,9.09,;1.65,10.42,;1.65,7.76,;3.77,3.34,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596973
(US11596639, Example 570)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cccc2cc(C(O)=O)n(Cc3cnn(C)n3)c12 |r,wD:1.0,(-.62,4.47,;-.62,2.93,;.91,3.09,;1.82,1.84,;1.19,.44,;2.08,-.82,;-.34,.27,;-1.25,-.97,;-.78,-2.44,;.73,-2.77,;1.22,-4.23,;2.72,-4.56,;3.21,-6.02,;4.72,-6.29,;5.25,-7.73,;6.76,-8.05,;4.26,-8.91,;4.73,-10.38,;2.74,-8.64,;1.78,-9.84,;2.22,-7.2,;-2.71,-.5,;-4.05,-1.27,;-5.38,-.5,;-5.38,1.04,;-6.75,1.75,;-4.05,1.81,;-4.05,3.35,;-5.29,4.26,;-6.76,3.78,;-4.82,5.72,;-3.28,5.72,;-2.51,7.06,;-2.8,4.26,;-1.34,3.78,;-2.71,1.04,;-1.25,1.52,;3.35,1.99,;4.24,.73,;5.78,.88,;6.41,2.28,;5.52,3.54,;5.85,5.04,;4.52,5.82,;4.38,7.36,;5.63,8.25,;2.97,7.99,;3.37,4.8,;1.87,5.13,;1.1,6.47,;-.44,6.47,;-.92,7.93,;.33,8.84,;.33,10.38,;1.57,7.93,;3.99,3.39,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596974
(US11596639, Example 571)Show SMILES COCCOc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)ncnc5C)c34)C2=O)c2n(Cc3cccc(C)n3)c(cc2c1)C(O)=O |r,wD:10.10,(6.97,-5.73,;6.07,-4.47,;6.71,-3.07,;5.81,-1.82,;6.45,-.42,;5.56,.84,;4.02,.69,;3.13,1.94,;1.6,1.8,;.69,3.04,;-.84,2.88,;-.84,4.42,;-1.47,1.47,;-.56,.23,;-1.47,-1.02,;-.99,-2.48,;.51,-2.81,;1,-4.27,;2.5,-4.6,;2.99,-6.06,;4.51,-6.33,;5.03,-7.78,;6.54,-8.1,;4.04,-8.96,;4.51,-10.42,;2.52,-8.69,;1.56,-9.89,;2,-7.24,;-2.93,-.54,;-4.26,-1.31,;-5.6,-.54,;-5.6,1,;-6.97,1.71,;-4.26,1.77,;-4.26,3.31,;-2.93,4.08,;-1.6,3.31,;-2.93,5.62,;-4.26,6.39,;-5.6,5.62,;-5.6,4.08,;-6.93,3.31,;-2.93,1,;.97,.39,;1.87,-.86,;3.77,3.34,;3.15,4.76,;1.65,5.09,;.88,6.42,;-.66,6.42,;-1.43,7.76,;-.66,9.09,;.88,9.09,;1.65,10.42,;1.65,7.76,;4.31,5.78,;5.63,5,;5.3,3.49,;6.2,2.24,;4.16,7.31,;5.41,8.2,;2.76,7.95,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596975
(US11596639, Example 572)Show SMILES COc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)ncnc5C)c34)C2=O)c2n(Cc3cccc(C)n3)c(cc2c1)C(O)=O |r,wD:7.7,(6.03,-1.82,;6.67,-.42,;5.77,.84,;4.24,.69,;3.34,1.94,;1.81,1.8,;.91,3.04,;-.63,2.88,;-.63,4.42,;-1.25,1.47,;-.35,.23,;-1.25,-1.02,;-.78,-2.48,;.73,-2.81,;1.21,-4.27,;2.72,-4.6,;3.2,-6.06,;4.72,-6.33,;5.25,-7.78,;6.75,-8.1,;4.26,-8.96,;4.73,-10.42,;2.74,-8.69,;1.77,-9.89,;2.21,-7.24,;-2.72,-.54,;-4.05,-1.31,;-5.38,-.54,;-5.38,1,;-6.75,1.71,;-4.05,1.77,;-4.05,3.31,;-2.72,4.08,;-1.38,3.31,;-2.72,5.62,;-4.05,6.39,;-5.38,5.62,;-5.38,4.08,;-6.72,3.31,;-2.72,1,;1.18,.39,;2.08,-.86,;3.98,3.34,;3.37,4.76,;1.86,5.09,;1.09,6.42,;-.45,6.42,;-1.22,7.76,;-.45,9.09,;1.09,9.09,;1.86,10.42,;1.86,7.76,;4.52,5.78,;5.85,5,;5.51,3.49,;6.41,2.24,;4.37,7.31,;5.63,8.2,;2.97,7.95,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596976
(US11596639, Example 573)Show SMILES COCCOc1cc(N2C[C@@H](C)n3c(c(CCCOc4cc(C)c(Cl)c(C)c4)c4ccc(Cl)c(-c5c(C)ncnc5C)c34)C2=O)c2n(Cc3cc(C)ccn3)c(cc2c1)C(O)=O |r,wD:10.10,(6.97,-5.73,;6.07,-4.47,;6.71,-3.07,;5.81,-1.82,;6.45,-.42,;5.56,.84,;4.02,.69,;3.13,1.94,;1.6,1.8,;.69,3.04,;-.84,2.88,;-.84,4.42,;-1.47,1.47,;-.56,.23,;-1.47,-1.02,;-.99,-2.48,;.51,-2.81,;1,-4.27,;2.5,-4.6,;2.99,-6.06,;4.51,-6.33,;5.03,-7.78,;6.54,-8.1,;4.04,-8.96,;4.51,-10.42,;2.52,-8.69,;1.56,-9.89,;2,-7.24,;-2.93,-.54,;-4.26,-1.31,;-5.6,-.54,;-5.6,1,;-6.97,1.71,;-4.26,1.77,;-4.26,3.31,;-2.93,4.08,;-1.6,3.31,;-2.93,5.62,;-4.26,6.39,;-5.6,5.62,;-5.6,4.08,;-6.93,3.31,;-2.93,1,;.97,.39,;1.87,-.86,;3.77,3.34,;3.15,4.76,;1.65,5.09,;.88,6.42,;1.65,7.76,;.88,9.09,;1.65,10.42,;-.66,9.09,;-1.43,7.76,;-.66,6.42,;4.31,5.78,;5.63,5,;5.3,3.49,;6.2,2.24,;4.16,7.31,;5.41,8.2,;2.76,7.95,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596978
(US11596639, Example 575)Show SMILES C[C@@H]1CN(c2cn(C)c3ncc(cc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(-.81,5.36,;-.81,3.82,;.72,3.98,;1.63,2.73,;3.16,2.89,;4.22,1.77,;5.61,2.44,;6.94,1.67,;5.41,3.96,;6.41,5.13,;5.9,6.59,;4.38,6.87,;3.38,5.7,;3.9,4.24,;3.87,8.32,;2.35,8.6,;4.87,9.49,;1,1.32,;1.9,.07,;-.53,1.16,;-1.43,-.08,;-.96,-1.55,;.54,-1.88,;1.03,-3.34,;2.53,-3.67,;3.02,-5.13,;4.54,-5.4,;5.06,-6.84,;6.57,-7.16,;4.07,-8.02,;4.55,-9.49,;2.56,-7.76,;1.59,-8.95,;2.03,-6.31,;-2.9,.39,;-4.23,-.38,;-5.57,.39,;-5.57,1.93,;-6.94,2.64,;-4.23,2.7,;-4.23,4.24,;-5.48,5.15,;-6.94,4.67,;-5,6.61,;-3.46,6.61,;-2.69,7.95,;-2.99,5.15,;-1.52,4.67,;-2.9,1.93,;-1.43,2.41,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596979
(US11596639, Example 576)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)ncnc4C)c3n12)c1cc(C)cc2cc(C(O)=O)n(Cc3cccc(C)n3)c12 |r,wD:1.0,(-.63,4.42,;-.63,2.88,;.91,3.04,;1.81,1.8,;1.18,.39,;2.08,-.86,;-.35,.23,;-1.25,-1.02,;-.78,-2.48,;.73,-2.81,;1.21,-4.27,;2.72,-4.6,;3.2,-6.06,;4.72,-6.33,;5.25,-7.78,;6.75,-8.1,;4.26,-8.96,;4.73,-10.42,;2.74,-8.69,;1.77,-9.89,;2.21,-7.24,;-2.72,-.54,;-4.05,-1.31,;-5.38,-.54,;-5.38,1,;-6.75,1.71,;-4.05,1.77,;-4.05,3.31,;-2.72,4.08,;-1.38,3.31,;-2.72,5.62,;-4.05,6.39,;-5.38,5.62,;-5.38,4.08,;-6.72,3.31,;-2.72,1,;-1.25,1.47,;3.34,1.94,;4.24,.69,;5.77,.84,;6.67,-.42,;6.41,2.24,;5.51,3.49,;5.85,5,;4.52,5.78,;4.37,7.31,;5.63,8.2,;2.97,7.95,;3.37,4.76,;1.86,5.09,;1.09,6.42,;-.45,6.42,;-1.22,7.76,;-.45,9.09,;1.09,9.09,;1.86,10.42,;1.86,7.76,;3.98,3.34,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596980
(US11596639, Example 577)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)ncnc4C)c3n12)c1cc(C)cc2cc(C(O)=O)n(Cc3cc(C)ccn3)c12 |r,wD:1.0,(-.63,4.42,;-.63,2.88,;.91,3.04,;1.81,1.8,;1.18,.39,;2.08,-.86,;-.35,.23,;-1.25,-1.02,;-.78,-2.48,;.73,-2.81,;1.21,-4.27,;2.72,-4.6,;3.2,-6.06,;4.72,-6.33,;5.25,-7.78,;6.75,-8.1,;4.26,-8.96,;4.73,-10.42,;2.74,-8.69,;1.77,-9.89,;2.21,-7.24,;-2.72,-.54,;-4.05,-1.31,;-5.38,-.54,;-5.38,1,;-6.75,1.71,;-4.05,1.77,;-4.05,3.31,;-2.72,4.08,;-1.38,3.31,;-2.72,5.62,;-4.05,6.39,;-5.38,5.62,;-5.38,4.08,;-6.72,3.31,;-2.72,1,;-1.25,1.47,;3.34,1.94,;4.24,.69,;5.77,.84,;6.67,-.42,;6.41,2.24,;5.51,3.49,;5.85,5,;4.52,5.78,;4.37,7.31,;5.63,8.2,;2.97,7.95,;3.37,4.76,;1.86,5.09,;1.09,6.42,;1.86,7.76,;1.09,9.09,;1.86,10.42,;-.45,9.09,;-1.22,7.76,;-.45,6.42,;3.98,3.34,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596981
(US11596639, Example 578)Show SMILES CC(C)OCCn1c(cc2cc(C)cc(N3C[C@@H](C)n4c(c(CCCOc5cc(C)c(Cl)c(C)c5)c5ccc(Cl)c(-c6c(C)nn(C)c6C)c45)C3=O)c12)C(O)=O |r,wD:17.17,(-.44,9.76,;-1.21,8.42,;-2.75,8.42,;-.44,7.09,;1.1,7.09,;1.87,5.76,;3.37,5.42,;4.52,6.44,;5.85,5.66,;5.52,4.16,;6.41,2.91,;5.78,1.5,;6.67,.25,;4.24,1.36,;3.35,2.61,;1.82,2.46,;.91,3.71,;-.62,3.55,;-.62,5.09,;-1.25,2.14,;-.34,.9,;-1.25,-.35,;-.78,-1.82,;.73,-2.15,;1.22,-3.61,;2.72,-3.94,;3.21,-5.4,;4.72,-5.66,;5.25,-7.11,;6.76,-7.43,;4.26,-8.29,;4.73,-9.76,;2.74,-8.02,;1.78,-9.22,;2.22,-6.58,;-2.71,.13,;-4.05,-.64,;-5.38,.13,;-5.38,1.67,;-6.75,2.37,;-4.05,2.44,;-4.05,3.98,;-5.29,4.88,;-6.76,4.4,;-4.82,6.35,;-3.28,6.35,;-2.51,7.68,;-2.8,4.88,;-1.34,4.4,;-2.71,1.67,;1.19,1.06,;2.08,-.2,;3.99,4.01,;4.38,7.98,;5.63,8.87,;2.97,8.61,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596982
(US11596639, Example 579)Show SMILES CCOCCn1c(cc2cc(C)cc(N3C[C@@H](C)n4c(c(CCCOc5cc(C)c(Cl)c(C)c5)c5ccc(Cl)c(-c6c(C)nn(C)c6C)c45)C3=O)c12)C(O)=O |r,wD:16.16,(-2.75,8.87,;-1.21,8.87,;-.44,7.53,;1.1,7.53,;1.87,6.2,;3.37,5.87,;4.52,6.89,;5.85,6.11,;5.52,4.6,;6.41,3.35,;5.78,1.95,;6.67,.69,;4.24,1.8,;3.35,3.05,;1.82,2.91,;.91,4.15,;-.62,3.99,;-.62,5.53,;-1.25,2.58,;-.34,1.34,;-1.25,.09,;-.78,-1.37,;.73,-1.7,;1.22,-3.16,;2.72,-3.49,;3.21,-4.95,;4.72,-5.22,;5.25,-6.67,;6.76,-6.99,;4.26,-7.85,;4.73,-9.31,;2.74,-7.58,;1.78,-8.78,;2.22,-6.13,;-2.71,.57,;-4.05,-.2,;-5.38,.57,;-5.38,2.11,;-6.75,2.81,;-4.05,2.88,;-4.05,4.42,;-5.29,5.32,;-6.76,4.85,;-4.82,6.79,;-3.28,6.79,;-2.51,8.12,;-2.8,5.32,;-1.34,4.85,;-2.71,2.11,;1.19,1.5,;2.08,.25,;3.99,4.45,;4.38,8.42,;5.63,9.31,;2.97,9.06,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596983
(US11596639, Example 580)Show SMILES C[C@@H]1CN(c2cn(CCN(C)C)c3ccc(cc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nc(CN5CCN(C)CC5)nc4C)c3n12 |r,wD:1.0,(-.83,4.13,;-.83,2.59,;.7,2.75,;1.61,1.5,;3.14,1.66,;4.2,.55,;5.59,1.21,;6.92,.44,;6.92,-1.1,;8.26,-1.87,;9.59,-1.1,;8.26,-3.41,;5.39,2.74,;6.39,3.91,;5.87,5.36,;4.36,5.64,;3.36,4.47,;3.87,3.02,;3.85,7.09,;2.33,7.37,;4.85,8.26,;.98,.1,;1.88,-1.16,;-.55,-.06,;-1.46,-1.31,;-.98,-2.78,;.52,-3.1,;1.01,-4.57,;2.51,-4.89,;3,-6.36,;4.52,-6.62,;5.04,-8.07,;6.55,-8.39,;4.05,-9.25,;4.52,-10.72,;2.53,-8.98,;1.57,-10.18,;2.01,-7.53,;-2.92,-.83,;-4.25,-1.6,;-5.59,-.83,;-5.59,.71,;-6.96,1.41,;-4.25,1.48,;-4.25,3.02,;-2.92,3.79,;-1.59,3.02,;-2.92,5.33,;-4.25,6.1,;-4.25,7.64,;-5.59,8.41,;-5.59,9.95,;-6.92,10.72,;-8.26,9.95,;-9.59,10.72,;-8.26,8.41,;-6.92,7.64,;-5.59,5.33,;-5.59,3.79,;-6.92,3.02,;-2.92,.71,;-1.46,1.18,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596987
(US11596639, Example 584)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)ncnc4C)c3n12)c1cc(OCCN(C)C)cc2cc(C(O)=O)n(Cc3cc(C)ccn3)c12 |r,wD:1.0,(-1.93,4.42,;-1.93,2.88,;-.39,3.04,;.51,1.8,;-.11,.39,;.78,-.86,;-1.65,.23,;-2.55,-1.02,;-2.08,-2.48,;-.57,-2.81,;-.09,-4.27,;1.42,-4.6,;1.9,-6.06,;3.42,-6.33,;3.95,-7.78,;5.45,-8.1,;2.96,-8.96,;3.43,-10.42,;1.44,-8.69,;.47,-9.89,;.91,-7.24,;-4.02,-.54,;-5.35,-1.31,;-6.68,-.54,;-6.68,1,;-8.05,1.71,;-5.35,1.77,;-5.35,3.31,;-4.02,4.08,;-2.68,3.31,;-4.02,5.62,;-5.35,6.39,;-6.68,5.62,;-6.68,4.08,;-8.02,3.31,;-4.02,1,;-2.55,1.47,;2.04,1.94,;2.94,.69,;4.47,.84,;5.37,-.42,;6.9,-.27,;7.8,-1.52,;7.16,-2.92,;5.62,-3.07,;8.05,-4.18,;5.11,2.24,;4.22,3.49,;4.55,5,;3.22,5.78,;3.07,7.31,;4.33,8.2,;1.67,7.95,;2.07,4.76,;.56,5.09,;-.21,6.42,;.56,7.76,;-.21,9.09,;.56,10.42,;-1.75,9.09,;-2.52,7.76,;-1.75,6.42,;2.68,3.34,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596988
(US11596639, Example 585)Show SMILES C[C@@H]1CN(c2cn(C)c3ncc(nc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12 |r,wD:1.0,(-.81,5.36,;-.81,3.82,;.72,3.98,;1.63,2.73,;3.16,2.89,;4.22,1.77,;5.61,2.44,;6.94,1.67,;5.41,3.96,;6.41,5.13,;5.9,6.59,;4.38,6.87,;3.38,5.7,;3.9,4.24,;3.87,8.32,;2.35,8.6,;4.87,9.49,;1,1.32,;1.9,.07,;-.53,1.16,;-1.43,-.08,;-.96,-1.55,;.54,-1.88,;1.03,-3.34,;2.53,-3.67,;3.02,-5.13,;4.54,-5.4,;5.06,-6.84,;6.57,-7.16,;4.07,-8.02,;4.55,-9.49,;2.56,-7.76,;1.59,-8.95,;2.03,-6.31,;-2.9,.39,;-4.23,-.38,;-5.57,.39,;-5.57,1.93,;-6.94,2.64,;-4.23,2.7,;-4.23,4.24,;-5.48,5.15,;-6.94,4.67,;-5,6.61,;-3.46,6.61,;-2.69,7.95,;-2.99,5.15,;-1.52,4.67,;-2.9,1.93,;-1.43,2.41,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596990
(US11596639, Example 587)Show SMILES COCCn1c(cc2c(OC)ccc(N3C[C@@H](C)n4c(c(CCCOc5cc(C)c(Cl)c(C)c5)c5ccc(Cl)c(-c6c(C)nn(C)c6C)c45)C3=O)c12)C(O)=O |r,wD:16.16,(-1.48,9.39,;-1.01,7.92,;.49,7.59,;.95,6.12,;2.46,5.79,;3.61,6.81,;4.94,6.03,;4.61,4.52,;5.5,3.27,;7.03,3.42,;7.67,4.82,;4.86,1.87,;3.33,1.72,;2.43,2.98,;.9,2.83,;-0,4.07,;-1.54,3.91,;-1.54,5.45,;-2.16,2.51,;-1.26,1.26,;-2.16,.02,;-1.69,-1.45,;-.18,-1.78,;.3,-3.24,;1.81,-3.57,;2.29,-5.03,;3.81,-5.3,;4.34,-6.75,;5.84,-7.07,;3.35,-7.93,;3.82,-9.39,;1.83,-7.66,;.86,-8.86,;1.3,-6.21,;-3.63,.49,;-4.96,-.28,;-6.29,.49,;-6.29,2.03,;-7.66,2.74,;-4.96,2.8,;-4.96,4.34,;-6.21,5.25,;-7.67,4.77,;-5.73,6.71,;-4.19,6.71,;-3.42,8.04,;-3.71,5.25,;-2.25,4.77,;-3.63,2.03,;.27,1.42,;1.17,.17,;3.07,4.38,;3.46,8.34,;4.72,9.24,;2.06,8.98,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596993
(US11596639, Example 590)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(OCCN(C)C)cc2cc(C(O)=O)n(Cc3ccccn3)c12 |r,wD:1.0,(-1.92,5.09,;-1.92,3.55,;-.39,3.71,;.52,2.46,;-.11,1.06,;.78,-.2,;-1.64,.9,;-2.55,-.35,;-2.07,-1.82,;-.57,-2.15,;-.08,-3.61,;1.42,-3.94,;1.91,-5.4,;3.42,-5.66,;3.95,-7.11,;5.46,-7.43,;2.96,-8.29,;3.43,-9.76,;1.44,-8.02,;.48,-9.22,;.92,-6.58,;-4.01,.13,;-5.35,-.64,;-6.68,.13,;-6.68,1.67,;-8.05,2.37,;-5.35,2.44,;-5.35,3.98,;-6.59,4.88,;-8.06,4.4,;-6.12,6.35,;-4.58,6.35,;-3.81,7.68,;-4.1,4.88,;-2.64,4.4,;-4.01,1.67,;-2.55,2.14,;2.05,2.61,;2.94,1.36,;4.48,1.5,;5.37,.25,;6.9,.4,;7.8,-.85,;7.16,-2.26,;5.63,-2.4,;8.06,-3.51,;5.11,2.91,;4.22,4.16,;4.55,5.66,;3.23,6.44,;3.08,7.98,;4.33,8.87,;1.67,8.61,;2.07,5.42,;.57,5.76,;-.2,7.09,;.57,8.42,;-.2,9.76,;-1.74,9.76,;-2.51,8.42,;-1.74,7.09,;2.69,4.01,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596994
(US11596639, Example 591)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(cc2cc(C(O)=O)n(C)c12)C(=O)N1CCOCC1 |r,wD:1.0,(-2.87,5.53,;-2.87,3.99,;-1.34,4.15,;-.44,2.91,;-1.06,1.5,;-.17,.25,;-2.59,1.34,;-3.5,.09,;-3.03,-1.37,;-1.52,-1.7,;-1.04,-3.16,;.47,-3.49,;.96,-4.95,;2.47,-5.22,;3,-6.67,;4.51,-6.99,;2.01,-7.85,;2.48,-9.31,;.49,-7.58,;-.48,-8.78,;-.03,-6.13,;-4.96,.57,;-6.3,-.2,;-7.63,.57,;-7.63,2.11,;-9,2.81,;-6.3,2.88,;-6.3,4.42,;-7.54,5.32,;-9.01,4.85,;-7.07,6.79,;-5.53,6.79,;-4.76,8.12,;-5.05,5.32,;-3.59,4.85,;-4.96,2.11,;-3.5,2.58,;1.1,3.05,;1.99,1.8,;3.52,1.95,;4.16,3.35,;3.27,4.6,;3.6,6.11,;2.27,6.89,;2.12,8.42,;3.38,9.31,;.72,9.06,;1.12,5.87,;-.38,6.2,;1.73,4.45,;4.42,.69,;3.78,-.71,;5.95,.84,;6.88,-.39,;8.41,-.2,;9.01,1.22,;8.08,2.45,;6.55,2.26,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM596995
(US11596639, Example 592)Show SMILES C[C@@H]1CN(C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12)c1cc(OCCN(C)C)cc2cc(C(O)=O)n(Cc3cccc(C)n3)c12 |r,wD:1.0,(-1.92,4.42,;-1.92,2.88,;-.39,3.04,;.52,1.8,;-.11,.39,;.78,-.86,;-1.64,.23,;-2.55,-1.02,;-2.07,-2.48,;-.57,-2.81,;-.08,-4.27,;1.42,-4.6,;1.91,-6.06,;3.42,-6.33,;3.95,-7.78,;5.46,-8.1,;2.96,-8.96,;3.43,-10.42,;1.44,-8.69,;.48,-9.89,;.92,-7.24,;-4.01,-.54,;-5.35,-1.31,;-6.68,-.54,;-6.68,1,;-8.05,1.71,;-5.35,1.77,;-5.35,3.31,;-6.59,4.21,;-8.06,3.74,;-6.12,5.68,;-4.58,5.68,;-3.81,7.01,;-4.1,4.21,;-2.64,3.74,;-4.01,1,;-2.55,1.47,;2.05,1.94,;2.94,.69,;4.48,.84,;5.37,-.42,;6.9,-.27,;7.8,-1.52,;7.16,-2.92,;5.63,-3.07,;8.06,-4.18,;5.11,2.24,;4.22,3.49,;4.55,5,;3.23,5.78,;3.08,7.31,;4.33,8.2,;1.67,7.95,;2.07,4.76,;.57,5.09,;-.2,6.42,;-1.74,6.42,;-2.51,7.76,;-1.74,9.09,;-.2,9.09,;.57,10.42,;.57,7.76,;2.69,3.34,)| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Measurements were carried out in OptiPlate-384 White Opaque 384-well plates (Perkin Elmer. Shelton, Conn.). The assay was run using a fluorescein iso... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2028WFX |
More data for this
Ligand-Target Pair | |
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