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Compile Data Set for Download or QSAR

Found 73 hits with Last Name = 'tber' and Initial = 'z'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin S


(Homo sapiens (Human))		BDBM50463221
PNG
(CHEMBL4251253)
Show SMILES FC(F)(F)Oc1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C15H13F3N6O2/c16-15(17,18)26-11-3-1-10(2-4-11)20-13-21-12(9-19)22-14(23-13)24-5-7-25-8-6-24/h1-4H,5-8H2,(H,20,21,22,23)
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 2n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by Cheng-Prusoff equation analysis

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463238
PNG
(CHEMBL4238973)
Show SMILES CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)CNC(C)=O)C(=O)NNC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H](C)C(=O)N[C@H](CCCNC(N)=N)C(N)=O |r|
Show InChI InChI=1S/C67H92N22O16S/c1-35(57(96)81-45(56(68)95)16-9-22-72-66(69)70)78-58(97)46(19-20-55(93)94)82-60(99)49(27-39-30-75-44-15-8-6-13-42(39)44)84-63(102)51-17-10-23-88(51)64(103)36(2)79-67(105)87-86-61(100)47(21-25-106-4)83-62(101)52-18-11-24-89(52)65(104)50(28-40-31-71-34-77-40)85-59(98)48(26-38-29-74-43-14-7-5-12-41(38)43)80-54(92)33-76-53(91)32-73-37(3)90/h5-8,12-15,29-31,34-36,45-52,74-75H,9-11,16-28,32-33H2,1-4H3,(H2,68,95)(H,71,77)(H,73,90)(H,76,91)(H,78,97)(H,80,92)(H,81,96)(H,82,99)(H,83,101)(H,84,102)(H,85,98)(H,86,100)(H,93,94)(H4,69,70,72)(H2,79,87,105)/t35-,36+,45-,46+,47+,48+,49+,50+,51+,52+/m1/s1
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 3n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by Cheng-Prusoff equation analysis

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463238
PNG
(CHEMBL4238973)
Show SMILES CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)CNC(C)=O)C(=O)NNC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H](C)C(=O)N[C@H](CCCNC(N)=N)C(N)=O |r|
Show InChI InChI=1S/C67H92N22O16S/c1-35(57(96)81-45(56(68)95)16-9-22-72-66(69)70)78-58(97)46(19-20-55(93)94)82-60(99)49(27-39-30-75-44-15-8-6-13-42(39)44)84-63(102)51-17-10-23-88(51)64(103)36(2)79-67(105)87-86-61(100)47(21-25-106-4)83-62(101)52-18-11-24-89(52)65(104)50(28-40-31-71-34-77-40)85-59(98)48(26-38-29-74-43-14-7-5-12-41(38)43)80-54(92)33-76-53(91)32-73-37(3)90/h5-8,12-15,29-31,34-36,45-52,74-75H,9-11,16-28,32-33H2,1-4H3,(H2,68,95)(H,71,77)(H,73,90)(H,76,91)(H,78,97)(H,80,92)(H,81,96)(H,82,99)(H,83,101)(H,84,102)(H,85,98)(H,86,100)(H,93,94)(H4,69,70,72)(H2,79,87,105)/t35-,36+,45-,46+,47+,48+,49+,50+,51+,52+/m1/s1
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 5n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by Cheng-Prusoff equation analysis

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463238
PNG
(CHEMBL4238973)
Show SMILES CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)CNC(C)=O)C(=O)NNC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H](C)C(=O)N[C@H](CCCNC(N)=N)C(N)=O |r|
Show InChI InChI=1S/C67H92N22O16S/c1-35(57(96)81-45(56(68)95)16-9-22-72-66(69)70)78-58(97)46(19-20-55(93)94)82-60(99)49(27-39-30-75-44-15-8-6-13-42(39)44)84-63(102)51-17-10-23-88(51)64(103)36(2)79-67(105)87-86-61(100)47(21-25-106-4)83-62(101)52-18-11-24-89(52)65(104)50(28-40-31-71-34-77-40)85-59(98)48(26-38-29-74-43-14-7-5-12-41(38)43)80-54(92)33-76-53(91)32-73-37(3)90/h5-8,12-15,29-31,34-36,45-52,74-75H,9-11,16-28,32-33H2,1-4H3,(H2,68,95)(H,71,77)(H,73,90)(H,76,91)(H,78,97)(H,80,92)(H,81,96)(H,82,99)(H,83,101)(H,84,102)(H,85,98)(H,86,100)(H,93,94)(H4,69,70,72)(H2,79,87,105)/t35-,36+,45-,46+,47+,48+,49+,50+,51+,52+/m1/s1
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 30n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by Cheng-Prusoff equation analysis

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463221
PNG
(CHEMBL4251253)
Show SMILES FC(F)(F)Oc1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C15H13F3N6O2/c16-15(17,18)26-11-3-1-10(2-4-11)20-13-21-12(9-19)22-14(23-13)24-5-7-25-8-6-24/h1-4H,5-8H2,(H,20,21,22,23)
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 700n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by Cheng-Prusoff equation analysis

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin B


(Homo sapiens (Human))		BDBM50463221
PNG
(CHEMBL4251253)
Show SMILES FC(F)(F)Oc1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C15H13F3N6O2/c16-15(17,18)26-11-3-1-10(2-4-11)20-13-21-12(9-19)22-14(23-13)24-5-7-25-8-6-24/h1-4H,5-8H2,(H,20,21,22,23)
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>5.00E+5n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by Cheng-Prusoff equation analysis

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463221
PNG
(CHEMBL4251253)
Show SMILES FC(F)(F)Oc1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C15H13F3N6O2/c16-15(17,18)26-11-3-1-10(2-4-11)20-13-21-12(9-19)22-14(23-13)24-5-7-25-8-6-24/h1-4H,5-8H2,(H,20,21,22,23)
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n/an/a 3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463223
PNG
(CHEMBL4237391)
Show SMILES [O-][N+](=O)c1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C15H16N8O2/c16-9-13-20-14(18-10-4-6-17-7-5-10)22-15(21-13)19-11-2-1-3-12(8-11)23(24)25/h1-3,8,10,17H,4-7H2,(H2,18,19,20,21,22)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463233
PNG
(CHEMBL4237987)
Show SMILES COc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C16H19N7O/c1-24-13-4-2-11(3-5-13)19-15-21-14(10-17)22-16(23-15)20-12-6-8-18-9-7-12/h2-5,12,18H,6-9H2,1H3,(H2,19,20,21,22,23)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463236
PNG
(CHEMBL4243796)
Show SMILES Fc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C15H16FN7/c16-10-1-3-11(4-2-10)19-14-21-13(9-17)22-15(23-14)20-12-5-7-18-8-6-12/h1-4,12,18H,5-8H2,(H2,19,20,21,22,23)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463222
PNG
(CHEMBL4246329)
Show SMILES Fc1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C14H13FN6O/c15-10-2-1-3-11(8-10)17-13-18-12(9-16)19-14(20-13)21-4-6-22-7-5-21/h1-3,8H,4-7H2,(H,17,18,19,20)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463230
PNG
(CHEMBL4248476)
Show SMILES [O-][N+](=O)c1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C14H13N7O3/c15-9-12-17-13(16-10-2-1-3-11(8-10)21(22)23)19-14(18-12)20-4-6-24-7-5-20/h1-3,8H,4-7H2,(H,16,17,18,19)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463231
PNG
(CHEMBL4249139)
Show SMILES Fc1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C14H13FN6O/c15-10-1-3-11(4-2-10)17-13-18-12(9-16)19-14(20-13)21-5-7-22-8-6-21/h1-4H,5-8H2,(H,17,18,19,20)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463237
PNG
(CHEMBL4245255)
Show SMILES [O-][N+](=O)c1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C14H13N7O3/c15-9-12-17-13(16-10-1-3-11(4-2-10)21(22)23)19-14(18-12)20-5-7-24-8-6-20/h1-4H,5-8H2,(H,16,17,18,19)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463226
PNG
(CHEMBL4248570)
Show SMILES COc1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C15H16N6O2/c1-22-12-4-2-11(3-5-12)17-14-18-13(10-16)19-15(20-14)21-6-8-23-9-7-21/h2-5H,6-9H2,1H3,(H,17,18,19,20)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463223
PNG
(CHEMBL4237391)
Show SMILES [O-][N+](=O)c1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C15H16N8O2/c16-9-13-20-14(18-10-4-6-17-7-5-10)22-15(21-13)19-11-2-1-3-12(8-11)23(24)25/h1-3,8,10,17H,4-7H2,(H2,18,19,20,21,22)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463223
PNG
(CHEMBL4237391)
Show SMILES [O-][N+](=O)c1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C15H16N8O2/c16-9-13-20-14(18-10-4-6-17-7-5-10)22-15(21-13)19-11-2-1-3-12(8-11)23(24)25/h1-3,8,10,17H,4-7H2,(H2,18,19,20,21,22)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463231
PNG
(CHEMBL4249139)
Show SMILES Fc1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C14H13FN6O/c15-10-1-3-11(4-2-10)17-13-18-12(9-16)19-14(20-13)21-5-7-22-8-6-21/h1-4H,5-8H2,(H,17,18,19,20)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463222
PNG
(CHEMBL4246329)
Show SMILES Fc1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C14H13FN6O/c15-10-2-1-3-11(8-10)17-13-18-12(9-16)19-14(20-13)21-4-6-22-7-5-21/h1-3,8H,4-7H2,(H,17,18,19,20)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463236
PNG
(CHEMBL4243796)
Show SMILES Fc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C15H16FN7/c16-10-1-3-11(4-2-10)19-14-21-13(9-17)22-15(23-14)20-12-5-7-18-8-6-12/h1-4,12,18H,5-8H2,(H2,19,20,21,22,23)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463228
PNG
(CHEMBL4240015)
Show SMILES FC(F)(F)Oc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C16H16F3N7O/c17-16(18,19)27-12-3-1-2-11(8-12)23-15-25-13(9-20)24-14(26-15)22-10-4-6-21-7-5-10/h1-3,8,10,21H,4-7H2,(H2,22,23,24,25,26)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463235
PNG
(CHEMBL4238536)
Show SMILES COc1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C15H16N6O2/c1-22-12-4-2-3-11(9-12)17-14-18-13(10-16)19-15(20-14)21-5-7-23-8-6-21/h2-4,9H,5-8H2,1H3,(H,17,18,19,20)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463229
PNG
(CHEMBL4243256)
Show SMILES FC(F)(F)Oc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C16H16F3N7O/c17-16(18,19)27-12-3-1-10(2-4-12)22-14-24-13(9-20)25-15(26-14)23-11-5-7-21-8-6-11/h1-4,11,21H,5-8H2,(H2,22,23,24,25,26)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463230
PNG
(CHEMBL4248476)
Show SMILES [O-][N+](=O)c1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C14H13N7O3/c15-9-12-17-13(16-10-2-1-3-11(8-10)21(22)23)19-14(18-12)20-4-6-24-7-5-20/h1-3,8H,4-7H2,(H,16,17,18,19)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463237
PNG
(CHEMBL4245255)
Show SMILES [O-][N+](=O)c1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C14H13N7O3/c15-9-12-17-13(16-10-1-3-11(4-2-10)21(22)23)19-14(18-12)20-5-7-24-8-6-20/h1-4H,5-8H2,(H,16,17,18,19)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463224
PNG
(CHEMBL4240103)
Show SMILES FC(F)(F)Oc1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C15H13F3N6O2/c16-15(17,18)26-11-3-1-2-10(8-11)20-13-21-12(9-19)22-14(23-13)24-4-6-25-7-5-24/h1-3,8H,4-7H2,(H,20,21,22,23)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463234
PNG
(CHEMBL4243348)
Show SMILES Fc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C15H16FN7/c16-10-2-1-3-12(8-10)20-15-22-13(9-17)21-14(23-15)19-11-4-6-18-7-5-11/h1-3,8,11,18H,4-7H2,(H2,19,20,21,22,23)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463230
PNG
(CHEMBL4248476)
Show SMILES [O-][N+](=O)c1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C14H13N7O3/c15-9-12-17-13(16-10-2-1-3-11(8-10)21(22)23)19-14(18-12)20-4-6-24-7-5-20/h1-3,8H,4-7H2,(H,16,17,18,19)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463225
PNG
(CHEMBL4247983)
Show SMILES COc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C16H19N7O/c1-24-13-4-2-3-12(9-13)20-16-22-14(10-17)21-15(23-16)19-11-5-7-18-8-6-11/h2-4,9,11,18H,5-8H2,1H3,(H2,19,20,21,22,23)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463228
PNG
(CHEMBL4240015)
Show SMILES FC(F)(F)Oc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C16H16F3N7O/c17-16(18,19)27-12-3-1-2-11(8-12)23-15-25-13(9-20)24-14(26-15)22-10-4-6-21-7-5-10/h1-3,8,10,21H,4-7H2,(H2,22,23,24,25,26)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463235
PNG
(CHEMBL4238536)
Show SMILES COc1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C15H16N6O2/c1-22-12-4-2-3-11(9-12)17-14-18-13(10-16)19-15(20-14)21-5-7-23-8-6-21/h2-4,9H,5-8H2,1H3,(H,17,18,19,20)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463229
PNG
(CHEMBL4243256)
Show SMILES FC(F)(F)Oc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C16H16F3N7O/c17-16(18,19)27-12-3-1-10(2-4-12)22-14-24-13(9-20)25-15(26-14)23-11-5-7-21-8-6-11/h1-4,11,21H,5-8H2,(H2,22,23,24,25,26)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463225
PNG
(CHEMBL4247983)
Show SMILES COc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C16H19N7O/c1-24-13-4-2-3-12(9-13)20-16-22-14(10-17)21-15(23-16)19-11-5-7-18-8-6-11/h2-4,9,11,18H,5-8H2,1H3,(H2,19,20,21,22,23)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463227
PNG
(CHEMBL4250979)
Show SMILES O[C@@H](CNc1nc(nc(n1)N1CCOCC1)C#N)c1ccccc1 |r|
Show InChI InChI=1S/C16H18N6O2/c17-10-14-19-15(18-11-13(23)12-4-2-1-3-5-12)21-16(20-14)22-6-8-24-9-7-22/h1-5,13,23H,6-9,11H2,(H,18,19,20,21)/t13-/m0/s1
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463234
PNG
(CHEMBL4243348)
Show SMILES Fc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C15H16FN7/c16-10-2-1-3-12(8-10)20-15-22-13(9-17)21-14(23-15)19-11-4-6-18-7-5-11/h1-3,8,11,18H,4-7H2,(H2,19,20,21,22,23)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463226
PNG
(CHEMBL4248570)
Show SMILES COc1ccc(Nc2nc(nc(n2)N2CCOCC2)C#N)cc1
Show InChI InChI=1S/C15H16N6O2/c1-22-12-4-2-11(3-5-12)17-14-18-13(10-16)19-15(20-14)21-6-8-23-9-7-21/h2-5H,6-9H2,1H3,(H,17,18,19,20)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463234
PNG
(CHEMBL4243348)
Show SMILES Fc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C15H16FN7/c16-10-2-1-3-12(8-10)20-15-22-13(9-17)21-14(23-15)19-11-4-6-18-7-5-11/h1-3,8,11,18H,4-7H2,(H2,19,20,21,22,23)
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Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463236
PNG
(CHEMBL4243796)
Show SMILES Fc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C15H16FN7/c16-10-1-3-11(4-2-10)19-14-21-13(9-17)22-15(23-14)20-12-5-7-18-8-6-12/h1-4,12,18H,5-8H2,(H2,19,20,21,22,23)
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n/an/a 400n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463228
PNG
(CHEMBL4240015)
Show SMILES FC(F)(F)Oc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C16H16F3N7O/c17-16(18,19)27-12-3-1-2-11(8-12)23-15-25-13(9-20)24-14(26-15)22-10-4-6-21-7-5-10/h1-3,8,10,21H,4-7H2,(H2,22,23,24,25,26)
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n/an/a 500n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463224
PNG
(CHEMBL4240103)
Show SMILES FC(F)(F)Oc1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C15H13F3N6O2/c16-15(17,18)26-11-3-1-2-10(8-11)20-13-21-12(9-19)22-14(23-13)24-4-6-25-7-5-24/h1-3,8H,4-7H2,(H,20,21,22,23)
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n/an/a 500n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463225
PNG
(CHEMBL4247983)
Show SMILES COc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1
Show InChI InChI=1S/C16H19N7O/c1-24-13-4-2-3-12(9-13)20-16-22-14(10-17)21-15(23-16)19-11-5-7-18-8-6-11/h2-4,9,11,18H,5-8H2,1H3,(H2,19,20,21,22,23)
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n/an/a 600n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463233
PNG
(CHEMBL4237987)
Show SMILES COc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C16H19N7O/c1-24-13-4-2-11(3-5-13)19-15-21-14(10-17)22-16(23-15)20-12-6-8-18-9-7-12/h2-5,12,18H,6-9H2,1H3,(H2,19,20,21,22,23)
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n/an/a 600n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463232
PNG
(CHEMBL4251370)
Show SMILES O[C@H](CNc1nc(nc(n1)N1CCOCC1)C#N)c1ccccc1 |r|
Show InChI InChI=1S/C16H18N6O2/c17-10-14-19-15(18-11-13(23)12-4-2-1-3-5-12)21-16(20-14)22-6-8-24-9-7-22/h1-5,13,23H,6-9,11H2,(H,18,19,20,21)/t13-/m1/s1
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n/an/a 700n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin S


(Homo sapiens (Human))		BDBM50463232
PNG
(CHEMBL4251370)
Show SMILES O[C@H](CNc1nc(nc(n1)N1CCOCC1)C#N)c1ccccc1 |r|
Show InChI InChI=1S/C16H18N6O2/c17-10-14-19-15(18-11-13(23)12-4-2-1-3-5-12)21-16(20-14)22-6-8-24-9-7-22/h1-5,13,23H,6-9,11H2,(H,18,19,20,21)/t13-/m1/s1
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n/an/a 800n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin B


(Homo sapiens (Human))		BDBM50463229
PNG
(CHEMBL4243256)
Show SMILES FC(F)(F)Oc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C16H16F3N7O/c17-16(18,19)27-12-3-1-10(2-4-12)22-14-24-13(9-20)25-15(26-14)23-11-5-7-21-8-6-11/h1-4,11,21H,5-8H2,(H2,22,23,24,25,26)
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n/an/a 800n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Cathepsin K


(Homo sapiens (Human))		BDBM50463227
PNG
(CHEMBL4250979)
Show SMILES O[C@@H](CNc1nc(nc(n1)N1CCOCC1)C#N)c1ccccc1 |r|
Show InChI InChI=1S/C16H18N6O2/c17-10-14-19-15(18-11-13(23)12-4-2-1-3-5-12)21-16(20-14)22-6-8-24-9-7-22/h1-5,13,23H,6-9,11H2,(H,18,19,20,21)/t13-/m0/s1
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n/an/a 800n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463222
PNG
(CHEMBL4246329)
Show SMILES Fc1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C14H13FN6O/c15-10-2-1-3-11(8-10)17-13-18-12(9-16)19-14(20-13)21-4-6-22-7-5-21/h1-3,8H,4-7H2,(H,17,18,19,20)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463233
PNG
(CHEMBL4237987)
Show SMILES COc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C16H19N7O/c1-24-13-4-2-11(3-5-13)19-15-21-14(10-17)22-16(23-15)20-12-6-8-18-9-7-12/h2-5,12,18H,6-9H2,1H3,(H2,19,20,21,22,23)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463229
PNG
(CHEMBL4243256)
Show SMILES FC(F)(F)Oc1ccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)cc1
Show InChI InChI=1S/C16H16F3N7O/c17-16(18,19)27-12-3-1-10(2-4-12)22-14-24-13(9-20)25-15(26-14)23-11-5-7-21-8-6-11/h1-4,11,21H,5-8H2,(H2,22,23,24,25,26)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
Procathepsin L


(Homo sapiens (Human))		BDBM50463235
PNG
(CHEMBL4238536)
Show SMILES COc1cccc(Nc2nc(nc(n2)N2CCOCC2)C#N)c1
Show InChI InChI=1S/C15H16N6O2/c1-22-12-4-2-3-11(9-12)17-14-18-13(10-16)19-15(20-14)21-5-7-23-8-6-21/h2-4,9H,5-8H2,1H3,(H,17,18,19,20)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric method

Bioorg Med Chem 26: 4310-4319 (2018)


Article DOI: 10.1016/j.bmc.2018.07.032
BindingDB Entry DOI: 10.7270/Q2P271RF
More data for this
Ligand-Target Pair
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