Compile Data Set for Download or QSAR

Found 18 hits with Last Name = 'togashi' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50384537 (CHEMBL2036430) Show SMILES CN(C)c1ccc(cc1)\N=N\c1nc2ccc(I)cc2s1 Show InChI InChI=1S/C15H13IN4S/c1-20(2)12-6-4-11(5-7-12)18-19-15-17-13-8-3-10(16)9-14(13)21-15/h3-9H,1-2H3/b19-18+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of Thioflavin S from recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assay				ACS Med Chem Lett 3: 58-62 (2012) Article DOI: 10.1021/ml200230e BindingDB Entry DOI: 10.7270/Q2PR7X1P
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492526 (CHEMBL2407616) Show SMILES CN(C)c1ccc(cc1)-c1cnc2cc(OCCF)ccc2n1 Show InChI InChI=1S/C18H18FN3O/c1-22(2)14-5-3-13(4-6-14)18-12-20-17-11-15(23-10-9-19)7-8-16(17)21-18/h3-8,11-12H,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.895	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma counting				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492522 (CHEMBL2407622) Show SMILES CN(C)c1ccc(cc1)-c1cnc2cc(OCC[18F])ccc2n1 Show InChI InChI=1S/C18H18FN3O/c1-22(2)14-5-3-13(4-6-14)18-12-20-17-11-15(23-10-9-19)7-8-16(17)21-18/h3-8,11-12H,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.895	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiography				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122787 (2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...) Show SMILES CN(C)c1ccc(cc1)-c1cn2cc(I)ccc2n1 Show InChI InChI=1S/C15H14IN3/c1-18(2)13-6-3-11(4-7-13)14-10-19-9-12(16)5-8-15(19)17-14/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma counting				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50384538 (CHEMBL2036419 | CHEMBL2036420) Show SMILES CN(C)c1ccc(cc1)\N=N\c1nc2ccc(OCCOCCOCCF)cc2s1 Show InChI InChI=1S/C21H25FN4O3S/c1-26(2)17-5-3-16(4-6-17)24-25-21-23-19-8-7-18(15-20(19)30-21)29-14-13-28-12-11-27-10-9-22/h3-8,15H,9-14H2,1-2H3/b25-24+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of Thioflavin S from recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assay				ACS Med Chem Lett 3: 58-62 (2012) Article DOI: 10.1021/ml200230e BindingDB Entry DOI: 10.7270/Q2PR7X1P
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492518 (Florbetapir | US10906900, AV45) Show SMILES CNc1ccc(\C=C\c2ccc(OCCOCCOCCF)nc2)cc1 Show InChI InChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma counting				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492516 (CHEMBL2407621) Show SMILES CNc1ccc(cc1)-c1cnc2cc(OCC[18F])ccc2n1 Show InChI InChI=1S/C17H16FN3O/c1-19-13-4-2-12(3-5-13)17-11-20-16-10-14(22-9-8-18)6-7-15(16)21-17/h2-7,10-11,19H,8-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiography				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492519 (CHEMBL2407615) Show SMILES CNc1ccc(cc1)-c1cnc2cc(OCCF)ccc2n1 Show InChI InChI=1S/C17H16FN3O/c1-19-13-4-2-12(3-5-13)17-11-20-16-10-14(22-9-8-18)6-7-15(16)21-17/h2-7,10-11,19H,8-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma counting				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492523 (CHEMBL2407623) Show SMILES CN(C)c1ccc(cc1)-c1cnc2ccc(OCCF)cc2n1 Show InChI InChI=1S/C18H18FN3O/c1-22(2)14-5-3-13(4-6-14)18-12-20-16-8-7-15(23-10-9-19)11-17(16)21-18/h3-8,11-12H,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiography				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492523 (CHEMBL2407623) Show SMILES CN(C)c1ccc(cc1)-c1cnc2ccc(OCCF)cc2n1 Show InChI InChI=1S/C18H18FN3O/c1-22(2)14-5-3-13(4-6-14)18-12-20-16-8-7-15(23-10-9-19)11-17(16)21-18/h3-8,11-12H,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma counting				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492517 (CHEMBL2407618) Show SMILES CNc1ccc(cc1)-c1cnc2ccc(OCC[18F])cc2n1 Show InChI InChI=1S/C17H16FN3O/c1-19-13-4-2-12(3-5-13)17-11-20-15-7-6-14(22-9-8-18)10-16(15)21-17/h2-7,10-11,19H,8-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiography				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492520 (CHEMBL2407624) Show SMILES Nc1ccc(cc1)-c1cnc2cc(OCCF)ccc2n1 Show InChI InChI=1S/C16H14FN3O/c17-7-8-21-13-5-6-14-15(9-13)19-10-16(20-14)11-1-3-12(18)4-2-11/h1-6,9-10H,7-8,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiography				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492521 (CHEMBL2407617) Show SMILES Nc1ccc(cc1)-c1cnc2ccc(OCC[18F])cc2n1 Show InChI InChI=1S/C16H14FN3O/c17-7-8-21-13-5-6-14-15(9-13)20-16(10-19-14)11-1-3-12(18)4-2-11/h1-6,9-10H,7-8,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiography				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492520 (CHEMBL2407624) Show SMILES Nc1ccc(cc1)-c1cnc2cc(OCCF)ccc2n1 Show InChI InChI=1S/C16H14FN3O/c17-7-8-21-13-5-6-14-15(9-13)19-10-16(20-14)11-1-3-12(18)4-2-11/h1-6,9-10H,7-8,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma counting				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492524 (CHEMBL2407625) Show SMILES CNc1ccc(cc1)-c1cnc2ccc(OCCF)cc2n1 Show InChI InChI=1S/C17H16FN3O/c1-19-13-4-2-12(3-5-13)17-11-20-15-7-6-14(22-9-8-18)10-16(15)21-17/h2-7,10-11,19H,8-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	758	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma counting				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50492525 (CHEMBL2407626) Show SMILES Nc1ccc(cc1)-c1cnc2ccc(OCCF)cc2n1 Show InChI InChI=1S/C16H14FN3O/c17-7-8-21-13-5-6-14-15(9-13)20-16(10-19-14)11-1-3-12(18)4-2-11/h1-6,9-10H,7-8,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma counting				ACS Med Chem Lett 4: 596-600 (2013) Article DOI: 10.1021/ml4000707 BindingDB Entry DOI: 10.7270/Q2RX9G0Z
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50384538 (CHEMBL2036419 | CHEMBL2036420) Show SMILES CN(C)c1ccc(cc1)\N=N\c1nc2ccc(OCCOCCOCCF)cc2s1 Show InChI InChI=1S/C21H25FN4O3S/c1-26(2)17-5-3-16(4-6-17)24-25-21-23-19-8-7-18(15-20(19)30-21)29-14-13-28-12-11-27-10-9-22/h3-8,15H,9-14H2,1-2H3/b25-24+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	256	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of Thioflavin S from recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assay				ACS Med Chem Lett 3: 58-62 (2012) Article DOI: 10.1021/ml200230e BindingDB Entry DOI: 10.7270/Q2PR7X1P
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50384538 (CHEMBL2036419 | CHEMBL2036420) Show SMILES CN(C)c1ccc(cc1)\N=N\c1nc2ccc(OCCOCCOCCF)cc2s1 Show InChI InChI=1S/C21H25FN4O3S/c1-26(2)17-5-3-16(4-6-17)24-25-21-23-19-8-7-18(15-20(19)30-21)29-14-13-28-12-11-27-10-9-22/h3-8,15H,9-14H2,1-2H3/b25-24+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	44.8	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assay				ACS Med Chem Lett 3: 58-62 (2012) Article DOI: 10.1021/ml200230e BindingDB Entry DOI: 10.7270/Q2PR7X1P
					More data for this Ligand-Target Pair