Found 44 hits with Last Name = 'tsuzuki' and Initial = 'k' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421355
(CHEMBL289955)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:22.23,10.9,30.32,37.39,48.52,12.18,44.47,c:43,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;8.36,3.47,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C40H69NO11/c1-16-29-40(12,46-15)34(43)25(7)32-22(4)18-39(11,52-32)35(51-37-31(42)28(17-23(5)48-37)41(13)21(2)3)26(8)33(27(9)36(44)49-29)50-30-20-38(10,45-14)19-24(6)47-30/h21,23-31,33,35,37,42H,16-20H2,1-15H3/t23?,24?,25-,26?,27?,28?,29?,30-,31+,33?,35+,37?,38-,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421358
(CHEMBL45141)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2CC(CC(C)O2)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:10.9,22.23,36.38,47.51,12.18,43.46,c:42,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;4.37,1.16,;5.69,1.93,;7.02,1.16,;7.02,-.38,;8.36,-1.15,;5.69,-1.15,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;8.36,3.47,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C40H69NO10/c1-16-30-40(12,45-15)35(42)26(7)33-23(4)19-39(11,51-33)36(50-31-18-29(17-24(5)46-31)41(13)22(2)3)27(8)34(28(9)37(43)48-30)49-32-21-38(10,44-14)20-25(6)47-32/h22,24-32,34,36H,16-21H2,1-15H3/t24?,25?,26-,27?,28?,29?,30?,31?,32-,34?,36+,38-,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421357
(CHEMBL297168)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:46.51,12.12,wD:22.23,10.9,30.32,35.37,46.50,12.18,42.45,c:41,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C38H65NO11/c1-15-27-38(10,44-14)32(41)23(5)30-20(2)17-37(9,50-30)33(49-35-29(40)26(39(11)12)16-21(3)46-35)24(6)31(25(7)34(42)47-27)48-28-19-36(8,43-13)18-22(4)45-28/h21-29,31,33,35,40H,15-19H2,1-14H3/t21?,22?,23-,24?,25?,26?,27?,28-,29+,31?,33+,35?,36-,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421355
(CHEMBL289955)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:22.23,10.9,30.32,37.39,48.52,12.18,44.47,c:43,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;8.36,3.47,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C40H69NO11/c1-16-29-40(12,46-15)34(43)25(7)32-22(4)18-39(11,52-32)35(51-37-31(42)28(17-23(5)48-37)41(13)21(2)3)26(8)33(27(9)36(44)49-29)50-30-20-38(10,45-14)19-24(6)47-30/h21,23-31,33,35,37,42H,16-20H2,1-15H3/t23?,24?,25-,26?,27?,28?,29?,30-,31+,33?,35+,37?,38-,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421354
(CHEMBL26966)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O |wU:48.53,12.12,wD:23.24,10.9,31.33,46.49,12.13,16.16,37.39,48.52,44.47,c:43,(-2.8,-3.98,;-2.77,-2.44,;-1.44,-1.68,;-1.44,-3.21,;-.13,-3.98,;-.13,-5.53,;1.22,-3.21,;2.56,-3.98,;1.22,-1.68,;2.53,-2.46,;3.87,-3.23,;3.87,-4.75,;5.2,-5.53,;3.84,-6.29,;6.53,-6.3,;6.53,-7.84,;6.53,-4.78,;7.86,-5.54,;6.53,-3.23,;7.89,-2.46,;5.2,-2.46,;2.56,-.91,;3.89,-1.68,;2.56,.65,;3.89,1.43,;5.22,2.2,;6.58,1.44,;7.89,2.21,;9.24,1.44,;7.89,3.76,;6.55,4.53,;5.22,3.76,;3.87,4.5,;6.55,6.07,;5.22,6.83,;7.89,6.84,;9.22,6.07,;1.22,1.4,;2.56,2.17,;1.22,2.95,;-.11,3.72,;-.13,5.26,;-1.44,2.95,;-.67,1.61,;-1.44,1.4,;-2.94,1.8,;-2.77,.63,;-4.32,.63,;-2.77,-.91,;-3.87,-2.01,;-4.32,-.91,)| Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50 |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421354
(CHEMBL26966)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O |wU:48.53,12.12,wD:23.24,10.9,31.33,46.49,12.13,16.16,37.39,48.52,44.47,c:43,(-2.8,-3.98,;-2.77,-2.44,;-1.44,-1.68,;-1.44,-3.21,;-.13,-3.98,;-.13,-5.53,;1.22,-3.21,;2.56,-3.98,;1.22,-1.68,;2.53,-2.46,;3.87,-3.23,;3.87,-4.75,;5.2,-5.53,;3.84,-6.29,;6.53,-6.3,;6.53,-7.84,;6.53,-4.78,;7.86,-5.54,;6.53,-3.23,;7.89,-2.46,;5.2,-2.46,;2.56,-.91,;3.89,-1.68,;2.56,.65,;3.89,1.43,;5.22,2.2,;6.58,1.44,;7.89,2.21,;9.24,1.44,;7.89,3.76,;6.55,4.53,;5.22,3.76,;3.87,4.5,;6.55,6.07,;5.22,6.83,;7.89,6.84,;9.22,6.07,;1.22,1.4,;2.56,2.17,;1.22,2.95,;-.11,3.72,;-.13,5.26,;-1.44,2.95,;-.67,1.61,;-1.44,1.4,;-2.94,1.8,;-2.77,.63,;-4.32,.63,;-2.77,-.91,;-3.87,-2.01,;-4.32,-.91,)| Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421356
(CHEMBL43313)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:22.23,10.9,30.32,36.38,47.51,12.18,43.46,c:42,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C39H67NO11/c1-15-28-39(11,45-14)33(42)24(6)31-21(3)18-38(10,51-31)34(50-36-30(41)27(40(12)16-2)17-22(4)47-36)25(7)32(26(8)35(43)48-28)49-29-20-37(9,44-13)19-23(5)46-29/h22-30,32,34,36,41H,15-20H2,1-14H3/t22?,23?,24-,25?,26?,27?,28?,29-,30+,32?,34+,36?,37-,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421356
(CHEMBL43313)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:22.23,10.9,30.32,36.38,47.51,12.18,43.46,c:42,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C39H67NO11/c1-15-28-39(11,45-14)33(42)24(6)31-21(3)18-38(10,51-31)34(50-36-30(41)27(40(12)16-2)17-22(4)47-36)25(7)32(26(8)35(43)48-28)49-29-20-37(9,44-13)19-23(5)46-29/h22-30,32,34,36,41H,15-20H2,1-14H3/t22?,23?,24-,25?,26?,27?,28?,29-,30+,32?,34+,36?,37-,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421349
(CHEMBL265495)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:23.24,10.9,31.33,12.13,16.16,37.39,48.52,44.47,c:43,(-1.68,-4.26,;-1.66,-2.72,;-.32,-1.96,;-.32,-3.49,;.99,-4.26,;.99,-5.8,;2.32,-3.49,;3.67,-4.26,;2.34,-1.96,;3.66,-2.74,;4.99,-3.51,;4.99,-5.03,;6.31,-5.81,;4.96,-6.57,;7.65,-6.58,;7.65,-8.12,;7.65,-5.05,;8.99,-5.82,;7.65,-3.51,;8.99,-2.74,;6.32,-2.74,;3.67,-1.19,;5.01,-1.96,;3.68,.37,;5.01,1.15,;6.34,1.92,;7.68,1.16,;9.01,1.93,;10.34,1.16,;9.01,3.48,;7.67,4.25,;6.32,3.46,;4.99,4.25,;7.65,5.79,;6.32,6.55,;9,6.56,;8.99,8.1,;2.35,1.12,;3.68,1.89,;2.35,2.67,;1.01,3.44,;1.01,4.98,;-.32,2.67,;.45,1.33,;-.32,1.12,;-1.82,1.52,;-1.65,.35,;-3.2,.35,;-1.65,-1.19,;-2.75,-2.29,;-3.2,-1.19,;-3.97,-2.5,)| Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50 |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421349
(CHEMBL265495)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:23.24,10.9,31.33,12.13,16.16,37.39,48.52,44.47,c:43,(-1.68,-4.26,;-1.66,-2.72,;-.32,-1.96,;-.32,-3.49,;.99,-4.26,;.99,-5.8,;2.32,-3.49,;3.67,-4.26,;2.34,-1.96,;3.66,-2.74,;4.99,-3.51,;4.99,-5.03,;6.31,-5.81,;4.96,-6.57,;7.65,-6.58,;7.65,-8.12,;7.65,-5.05,;8.99,-5.82,;7.65,-3.51,;8.99,-2.74,;6.32,-2.74,;3.67,-1.19,;5.01,-1.96,;3.68,.37,;5.01,1.15,;6.34,1.92,;7.68,1.16,;9.01,1.93,;10.34,1.16,;9.01,3.48,;7.67,4.25,;6.32,3.46,;4.99,4.25,;7.65,5.79,;6.32,6.55,;9,6.56,;8.99,8.1,;2.35,1.12,;3.68,1.89,;2.35,2.67,;1.01,3.44,;1.01,4.98,;-.32,2.67,;.45,1.33,;-.32,1.12,;-1.82,1.52,;-1.65,.35,;-3.2,.35,;-1.65,-1.19,;-2.75,-2.29,;-3.2,-1.19,;-3.97,-2.5,)| Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421357
(CHEMBL297168)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:46.51,12.12,wD:22.23,10.9,30.32,35.37,46.50,12.18,42.45,c:41,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C38H65NO11/c1-15-27-38(10,44-14)32(41)23(5)30-20(2)17-37(9,50-30)33(49-35-29(40)26(39(11)12)16-21(3)46-35)24(6)31(25(7)34(42)47-27)48-28-19-36(8,43-13)18-22(4)45-28/h21-29,31,33,35,40H,15-19H2,1-14H3/t21?,22?,23-,24?,25?,26?,27?,28-,29+,31?,33+,35?,36-,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421351
(CHEMBL27424)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:49.54,12.12,wD:23.24,10.9,31.33,12.13,16.16,38.40,49.53,45.48,c:44,(-1.28,-6.37,;-1.26,-4.82,;.08,-4.07,;.08,-5.6,;1.39,-6.36,;1.39,-7.9,;2.72,-5.6,;4.07,-6.37,;2.74,-4.07,;4.05,-4.84,;5.39,-5.61,;5.39,-7.14,;6.71,-7.91,;5.36,-8.67,;8.04,-8.68,;8.04,-10.23,;8.05,-7.15,;9.38,-7.93,;8.05,-5.61,;9.38,-4.84,;6.72,-4.84,;4.07,-3.3,;5.41,-4.07,;4.08,-1.74,;5.41,-.96,;6.74,-.17,;8.07,-.94,;9.41,-.17,;10.74,-.94,;9.41,1.37,;8.07,2.14,;6.72,1.36,;5.39,2.13,;8.05,3.69,;6.72,4.44,;9.4,4.46,;9.38,6,;10.73,3.69,;2.74,-.98,;4.08,-.21,;2.74,.56,;1.41,1.33,;1.4,2.88,;.08,.56,;.85,-.77,;.08,-.98,;-1.42,-.58,;-1.25,-1.75,;-2.8,-1.75,;-1.25,-3.3,;-2.35,-4.4,;-2.8,-3.3,;-3.58,-4.61,)| Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50 |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421351
(CHEMBL27424)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:49.54,12.12,wD:23.24,10.9,31.33,12.13,16.16,38.40,49.53,45.48,c:44,(-1.28,-6.37,;-1.26,-4.82,;.08,-4.07,;.08,-5.6,;1.39,-6.36,;1.39,-7.9,;2.72,-5.6,;4.07,-6.37,;2.74,-4.07,;4.05,-4.84,;5.39,-5.61,;5.39,-7.14,;6.71,-7.91,;5.36,-8.67,;8.04,-8.68,;8.04,-10.23,;8.05,-7.15,;9.38,-7.93,;8.05,-5.61,;9.38,-4.84,;6.72,-4.84,;4.07,-3.3,;5.41,-4.07,;4.08,-1.74,;5.41,-.96,;6.74,-.17,;8.07,-.94,;9.41,-.17,;10.74,-.94,;9.41,1.37,;8.07,2.14,;6.72,1.36,;5.39,2.13,;8.05,3.69,;6.72,4.44,;9.4,4.46,;9.38,6,;10.73,3.69,;2.74,-.98,;4.08,-.21,;2.74,.56,;1.41,1.33,;1.4,2.88,;.08,.56,;.85,-.77,;.08,-.98,;-1.42,-.58,;-1.25,-1.75,;-2.8,-1.75,;-1.25,-3.3,;-2.35,-4.4,;-2.8,-3.3,;-3.58,-4.61,)| Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421349
(CHEMBL265495)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:23.24,10.9,31.33,12.13,16.16,37.39,48.52,44.47,c:43,(-1.68,-4.26,;-1.66,-2.72,;-.32,-1.96,;-.32,-3.49,;.99,-4.26,;.99,-5.8,;2.32,-3.49,;3.67,-4.26,;2.34,-1.96,;3.66,-2.74,;4.99,-3.51,;4.99,-5.03,;6.31,-5.81,;4.96,-6.57,;7.65,-6.58,;7.65,-8.12,;7.65,-5.05,;8.99,-5.82,;7.65,-3.51,;8.99,-2.74,;6.32,-2.74,;3.67,-1.19,;5.01,-1.96,;3.68,.37,;5.01,1.15,;6.34,1.92,;7.68,1.16,;9.01,1.93,;10.34,1.16,;9.01,3.48,;7.67,4.25,;6.32,3.46,;4.99,4.25,;7.65,5.79,;6.32,6.55,;9,6.56,;8.99,8.1,;2.35,1.12,;3.68,1.89,;2.35,2.67,;1.01,3.44,;1.01,4.98,;-.32,2.67,;.45,1.33,;-.32,1.12,;-1.82,1.52,;-1.65,.35,;-3.2,.35,;-1.65,-1.19,;-2.75,-2.29,;-3.2,-1.19,;-3.97,-2.5,)| Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421349
(CHEMBL265495)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:23.24,10.9,31.33,12.13,16.16,37.39,48.52,44.47,c:43,(-1.68,-4.26,;-1.66,-2.72,;-.32,-1.96,;-.32,-3.49,;.99,-4.26,;.99,-5.8,;2.32,-3.49,;3.67,-4.26,;2.34,-1.96,;3.66,-2.74,;4.99,-3.51,;4.99,-5.03,;6.31,-5.81,;4.96,-6.57,;7.65,-6.58,;7.65,-8.12,;7.65,-5.05,;8.99,-5.82,;7.65,-3.51,;8.99,-2.74,;6.32,-2.74,;3.67,-1.19,;5.01,-1.96,;3.68,.37,;5.01,1.15,;6.34,1.92,;7.68,1.16,;9.01,1.93,;10.34,1.16,;9.01,3.48,;7.67,4.25,;6.32,3.46,;4.99,4.25,;7.65,5.79,;6.32,6.55,;9,6.56,;8.99,8.1,;2.35,1.12,;3.68,1.89,;2.35,2.67,;1.01,3.44,;1.01,4.98,;-.32,2.67,;.45,1.33,;-.32,1.12,;-1.82,1.52,;-1.65,.35,;-3.2,.35,;-1.65,-1.19,;-2.75,-2.29,;-3.2,-1.19,;-3.97,-2.5,)| Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | 2.5 | 25 |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo... |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108830
(2-Amino-N-[6-(3-tert-butyl-4-hydroxy-benzyl)-2,5,8...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C30H41N5O5/c1-30(2,3)21-15-20(12-13-25(21)36)17-24-28(39)33-18-26(37)32-14-8-7-11-23(29(40)35-24)34-27(38)22(31)16-19-9-5-4-6-10-19/h4-6,9-10,12-13,15,22-24,36H,7-8,11,14,16-18,31H2,1-3H3,(H,32,37)(H,33,39)(H,34,38)(H,35,40) | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421351
(CHEMBL27424)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:49.54,12.12,wD:23.24,10.9,31.33,12.13,16.16,38.40,49.53,45.48,c:44,(-1.28,-6.37,;-1.26,-4.82,;.08,-4.07,;.08,-5.6,;1.39,-6.36,;1.39,-7.9,;2.72,-5.6,;4.07,-6.37,;2.74,-4.07,;4.05,-4.84,;5.39,-5.61,;5.39,-7.14,;6.71,-7.91,;5.36,-8.67,;8.04,-8.68,;8.04,-10.23,;8.05,-7.15,;9.38,-7.93,;8.05,-5.61,;9.38,-4.84,;6.72,-4.84,;4.07,-3.3,;5.41,-4.07,;4.08,-1.74,;5.41,-.96,;6.74,-.17,;8.07,-.94,;9.41,-.17,;10.74,-.94,;9.41,1.37,;8.07,2.14,;6.72,1.36,;5.39,2.13,;8.05,3.69,;6.72,4.44,;9.4,4.46,;9.38,6,;10.73,3.69,;2.74,-.98,;4.08,-.21,;2.74,.56,;1.41,1.33,;1.4,2.88,;.08,.56,;.85,-.77,;.08,-.98,;-1.42,-.58,;-1.25,-1.75,;-2.8,-1.75,;-1.25,-3.3,;-2.35,-4.4,;-2.8,-3.3,;-3.58,-4.61,)| Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421351
(CHEMBL27424)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:49.54,12.12,wD:23.24,10.9,31.33,12.13,16.16,38.40,49.53,45.48,c:44,(-1.28,-6.37,;-1.26,-4.82,;.08,-4.07,;.08,-5.6,;1.39,-6.36,;1.39,-7.9,;2.72,-5.6,;4.07,-6.37,;2.74,-4.07,;4.05,-4.84,;5.39,-5.61,;5.39,-7.14,;6.71,-7.91,;5.36,-8.67,;8.04,-8.68,;8.04,-10.23,;8.05,-7.15,;9.38,-7.93,;8.05,-5.61,;9.38,-4.84,;6.72,-4.84,;4.07,-3.3,;5.41,-4.07,;4.08,-1.74,;5.41,-.96,;6.74,-.17,;8.07,-.94,;9.41,-.17,;10.74,-.94,;9.41,1.37,;8.07,2.14,;6.72,1.36,;5.39,2.13,;8.05,3.69,;6.72,4.44,;9.4,4.46,;9.38,6,;10.73,3.69,;2.74,-.98,;4.08,-.21,;2.74,.56,;1.41,1.33,;1.4,2.88,;.08,.56,;.85,-.77,;.08,-.98,;-1.42,-.58,;-1.25,-1.75,;-2.8,-1.75,;-1.25,-3.3,;-2.35,-4.4,;-2.8,-3.3,;-3.58,-4.61,)| Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | 2.5 | 25 |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo... |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421350
(CHEMBL27419)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:23.24,10.9,31.33,12.13,16.16,36.38,47.51,43.46,c:42,(-1.7,-4.4,;-1.68,-2.85,;-.34,-2.09,;-.34,-3.62,;.97,-4.38,;.97,-5.92,;2.3,-3.62,;3.66,-4.4,;2.32,-2.09,;3.63,-2.86,;4.96,-3.63,;4.96,-5.17,;6.3,-5.94,;4.94,-6.69,;7.63,-6.71,;7.63,-8.25,;7.63,-5.18,;8.96,-5.95,;7.63,-3.63,;8.96,-2.86,;6.3,-2.86,;3.66,-1.32,;4.99,-2.09,;3.66,.23,;4.99,1.02,;6.32,1.79,;7.65,1.03,;8.99,1.8,;10.32,1.03,;8.99,3.34,;7.65,4.13,;6.3,3.34,;4.96,4.11,;7.63,5.66,;8.99,6.43,;6.3,6.42,;2.32,1,;3.66,1.77,;2.32,2.54,;.99,3.31,;.99,4.86,;-.34,2.54,;.43,1.21,;-.34,1,;-1.84,1.39,;-1.68,.23,;-3.22,.23,;-1.68,-1.32,;-2.77,-2.42,;-3.22,-1.32,;-3.99,-2.63,)| Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421350
(CHEMBL27419)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:23.24,10.9,31.33,12.13,16.16,36.38,47.51,43.46,c:42,(-1.7,-4.4,;-1.68,-2.85,;-.34,-2.09,;-.34,-3.62,;.97,-4.38,;.97,-5.92,;2.3,-3.62,;3.66,-4.4,;2.32,-2.09,;3.63,-2.86,;4.96,-3.63,;4.96,-5.17,;6.3,-5.94,;4.94,-6.69,;7.63,-6.71,;7.63,-8.25,;7.63,-5.18,;8.96,-5.95,;7.63,-3.63,;8.96,-2.86,;6.3,-2.86,;3.66,-1.32,;4.99,-2.09,;3.66,.23,;4.99,1.02,;6.32,1.79,;7.65,1.03,;8.99,1.8,;10.32,1.03,;8.99,3.34,;7.65,4.13,;6.3,3.34,;4.96,4.11,;7.63,5.66,;8.99,6.43,;6.3,6.42,;2.32,1,;3.66,1.77,;2.32,2.54,;.99,3.31,;.99,4.86,;-.34,2.54,;.43,1.21,;-.34,1,;-1.84,1.39,;-1.68,.23,;-3.22,.23,;-1.68,-1.32,;-2.77,-2.42,;-3.22,-1.32,;-3.99,-2.63,)| Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | 2.5 | 25 |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo... |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421350
(CHEMBL27419)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:23.24,10.9,31.33,12.13,16.16,36.38,47.51,43.46,c:42,(-1.7,-4.4,;-1.68,-2.85,;-.34,-2.09,;-.34,-3.62,;.97,-4.38,;.97,-5.92,;2.3,-3.62,;3.66,-4.4,;2.32,-2.09,;3.63,-2.86,;4.96,-3.63,;4.96,-5.17,;6.3,-5.94,;4.94,-6.69,;7.63,-6.71,;7.63,-8.25,;7.63,-5.18,;8.96,-5.95,;7.63,-3.63,;8.96,-2.86,;6.3,-2.86,;3.66,-1.32,;4.99,-2.09,;3.66,.23,;4.99,1.02,;6.32,1.79,;7.65,1.03,;8.99,1.8,;10.32,1.03,;8.99,3.34,;7.65,4.13,;6.3,3.34,;4.96,4.11,;7.63,5.66,;8.99,6.43,;6.3,6.42,;2.32,1,;3.66,1.77,;2.32,2.54,;.99,3.31,;.99,4.86,;-.34,2.54,;.43,1.21,;-.34,1,;-1.84,1.39,;-1.68,.23,;-3.22,.23,;-1.68,-1.32,;-2.77,-2.42,;-3.22,-1.32,;-3.99,-2.63,)| Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | 2.5 | 25 |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo... |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421350
(CHEMBL27419)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:23.24,10.9,31.33,12.13,16.16,36.38,47.51,43.46,c:42,(-1.7,-4.4,;-1.68,-2.85,;-.34,-2.09,;-.34,-3.62,;.97,-4.38,;.97,-5.92,;2.3,-3.62,;3.66,-4.4,;2.32,-2.09,;3.63,-2.86,;4.96,-3.63,;4.96,-5.17,;6.3,-5.94,;4.94,-6.69,;7.63,-6.71,;7.63,-8.25,;7.63,-5.18,;8.96,-5.95,;7.63,-3.63,;8.96,-2.86,;6.3,-2.86,;3.66,-1.32,;4.99,-2.09,;3.66,.23,;4.99,1.02,;6.32,1.79,;7.65,1.03,;8.99,1.8,;10.32,1.03,;8.99,3.34,;7.65,4.13,;6.3,3.34,;4.96,4.11,;7.63,5.66,;8.99,6.43,;6.3,6.42,;2.32,1,;3.66,1.77,;2.32,2.54,;.99,3.31,;.99,4.86,;-.34,2.54,;.43,1.21,;-.34,1,;-1.84,1.39,;-1.68,.23,;-3.22,.23,;-1.68,-1.32,;-2.77,-2.42,;-3.22,-1.32,;-3.99,-2.63,)| Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108832
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C31H43N5O5/c1-31(2,3)22-17-21(12-13-26(22)37)19-25-29(40)34-16-14-27(38)33-15-8-7-11-24(30(41)36-25)35-28(39)23(32)18-20-9-5-4-6-10-20/h4-6,9-10,12-13,17,23-25,37H,7-8,11,14-16,18-19,32H2,1-3H3,(H,33,38)(H,34,40)(H,35,39)(H,36,41) | Reactome pathway
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| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108833
(2-Amino-N-[3-(3-tert-butyl-4-hydroxy-benzyl)-2,5,1...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCCCCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C34H49N5O5/c1-34(2,3)25-20-24(16-17-29(25)40)22-28-32(43)37-19-10-5-8-15-30(41)36-18-11-9-14-27(33(44)39-28)38-31(42)26(35)21-23-12-6-4-7-13-23/h4,6-7,12-13,16-17,20,26-28,40H,5,8-11,14-15,18-19,21-22,35H2,1-3H3,(H,36,41)(H,37,43)(H,38,42)(H,39,44) | Reactome pathway
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Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108829
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,8,1...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C32H45N5O5/c1-32(2,3)23-18-22(14-15-27(23)38)20-26-30(41)35-17-9-13-28(39)34-16-8-7-12-25(31(42)37-26)36-29(40)24(33)19-21-10-5-4-6-11-21/h4-6,10-11,14-15,18,24-26,38H,7-9,12-13,16-17,19-20,33H2,1-3H3,(H,34,39)(H,35,41)(H,36,40)(H,37,42) | Reactome pathway
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Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108830
(2-Amino-N-[6-(3-tert-butyl-4-hydroxy-benzyl)-2,5,8...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C30H41N5O5/c1-30(2,3)21-15-20(12-13-25(21)36)17-24-28(39)33-18-26(37)32-14-8-7-11-23(29(40)35-24)34-27(38)22(31)16-19-9-5-4-6-10-19/h4-6,9-10,12-13,15,22-24,36H,7-8,11,14,16-18,31H2,1-3H3,(H,32,37)(H,33,39)(H,34,38)(H,35,40) | Reactome pathway
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Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108829
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,8,1...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C32H45N5O5/c1-32(2,3)23-18-22(14-15-27(23)38)20-26-30(41)35-17-9-13-28(39)34-16-8-7-12-25(31(42)37-26)36-29(40)24(33)19-21-10-5-4-6-11-21/h4-6,10-11,14-15,18,24-26,38H,7-9,12-13,16-17,19-20,33H2,1-3H3,(H,34,39)(H,35,41)(H,36,40)(H,37,42) | Reactome pathway
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Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108833
(2-Amino-N-[3-(3-tert-butyl-4-hydroxy-benzyl)-2,5,1...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCCCCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C34H49N5O5/c1-34(2,3)25-20-24(16-17-29(25)40)22-28-32(43)37-19-10-5-8-15-30(41)36-18-11-9-14-27(33(44)39-28)38-31(42)26(35)21-23-12-6-4-7-13-23/h4,6-7,12-13,16-17,20,26-28,40H,5,8-11,14-15,18-19,21-22,35H2,1-3H3,(H,36,41)(H,37,43)(H,38,42)(H,39,44) | Reactome pathway
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Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421353
(CHEMBL406517)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O Show InChI InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19?,20+,21?,22?,23?,24?,25?,26+,28-,29?,30-,31+,32-,34?,35+,36-,37-/m1/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo... |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421353
(CHEMBL406517)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O Show InChI InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19?,20+,21?,22?,23?,24?,25?,26+,28-,29?,30-,31+,32-,34?,35+,36-,37-/m1/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo... |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421352
(CHEMBL281952)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)C3(O2)O[C@]1(C)[C@H](O)[C@H]3C Show InChI InChI=1S/C37H65NO12/c1-14-25-36(10)29(40)22(6)37(50-36)18(2)16-35(9,49-37)31(48-33-27(39)24(38(11)12)15-19(3)44-33)20(4)28(21(5)32(42)46-25)47-26-17-34(8,43-13)30(41)23(7)45-26/h18-31,33,39-41H,14-17H2,1-13H3/t18?,19?,20?,21?,22-,23?,24?,25?,26+,27-,28?,29-,30+,31-,33?,34-,35+,36+,37?/m1/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50 |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421352
(CHEMBL281952)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)C3(O2)O[C@]1(C)[C@H](O)[C@H]3C Show InChI InChI=1S/C37H65NO12/c1-14-25-36(10)29(40)22(6)37(50-36)18(2)16-35(9,49-37)31(48-33-27(39)24(38(11)12)15-19(3)44-33)20(4)28(21(5)32(42)46-25)47-26-17-34(8,43-13)30(41)23(7)45-26/h18-31,33,39-41H,14-17H2,1-13H3/t18?,19?,20?,21?,22-,23?,24?,25?,26+,27-,28?,29-,30+,31-,33?,34-,35+,36+,37?/m1/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50 |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM85846
(CAS_33396-29-1 | EM523 | Erythromycin A 6,9-enolet...)Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O |r,wU:36.38,25.25,47.52,6.6,43.46,45.48,12.13,30.34,10.9,16.16,27.28,wD:8.8,23.24,47.51,31.33,21.22,12.12,2.1,18.18,c:42,(-6.58,-.4,;-6.58,1.13,;-5.23,1.91,;-3.9,1.13,;-3.9,-.4,;-5.23,-1.2,;-2.57,-1.2,;-2.57,-2.73,;-1.22,-.4,;.11,-1.2,;.11,-2.73,;1.44,-3.5,;1.44,-5.03,;2.99,-5.03,;2.19,-6.39,;3.75,-6.39,;.11,-5.81,;.11,-7.36,;-1.22,-5.03,;-2.57,-5.81,;-1.22,-3.5,;-1.22,1.13,;-2.57,1.91,;.11,1.91,;1.44,1.13,;2.77,1.91,;4.1,1.13,;5.45,1.91,;6.78,1.13,;5.45,3.44,;4.1,4.21,;2.77,3.44,;1.44,4.21,;4.1,5.76,;2.77,6.52,;5.45,6.52,;.11,3.44,;1.64,3.44,;.44,4.9,;-.44,6.16,;.55,7.36,;-2.33,6.72,;-1.88,4.46,;-3.9,5.76,;-5.23,6.52,;-3.9,4.21,;-2.57,3.44,;-5.23,3.44,;-6.78,3.44,;-6.01,4.79,)| Show InChI InChI=1S/C37H65NO12/c1-14-25-37(10,43)30(40)20(4)28-18(2)16-36(9,50-28)32(49-34-27(39)24(38(11)12)15-19(3)45-34)21(5)29(22(6)33(42)47-25)48-26-17-35(8,44-13)31(41)23(7)46-26/h19-27,29-32,34,39-41,43H,14-17H2,1-13H3/t19-,20+,21+,22-,23+,24+,25-,26+,27-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1 | Reactome pathway
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| n/a | n/a | 224 | n/a | n/a | n/a | n/a | 2.5 | 25 |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo... |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM85846
(CAS_33396-29-1 | EM523 | Erythromycin A 6,9-enolet...)Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O |r,wU:36.38,25.25,47.52,6.6,43.46,45.48,12.13,30.34,10.9,16.16,27.28,wD:8.8,23.24,47.51,31.33,21.22,12.12,2.1,18.18,c:42,(-6.58,-.4,;-6.58,1.13,;-5.23,1.91,;-3.9,1.13,;-3.9,-.4,;-5.23,-1.2,;-2.57,-1.2,;-2.57,-2.73,;-1.22,-.4,;.11,-1.2,;.11,-2.73,;1.44,-3.5,;1.44,-5.03,;2.99,-5.03,;2.19,-6.39,;3.75,-6.39,;.11,-5.81,;.11,-7.36,;-1.22,-5.03,;-2.57,-5.81,;-1.22,-3.5,;-1.22,1.13,;-2.57,1.91,;.11,1.91,;1.44,1.13,;2.77,1.91,;4.1,1.13,;5.45,1.91,;6.78,1.13,;5.45,3.44,;4.1,4.21,;2.77,3.44,;1.44,4.21,;4.1,5.76,;2.77,6.52,;5.45,6.52,;.11,3.44,;1.64,3.44,;.44,4.9,;-.44,6.16,;.55,7.36,;-2.33,6.72,;-1.88,4.46,;-3.9,5.76,;-5.23,6.52,;-3.9,4.21,;-2.57,3.44,;-5.23,3.44,;-6.78,3.44,;-6.01,4.79,)| Show InChI InChI=1S/C37H65NO12/c1-14-25-37(10,43)30(40)20(4)28-18(2)16-36(9,50-28)32(49-34-27(39)24(38(11)12)15-19(3)45-34)21(5)29(22(6)33(42)47-25)48-26-17-35(8,44-13)31(41)23(7)46-26/h19-27,29-32,34,39-41,43H,14-17H2,1-13H3/t19-,20+,21+,22-,23+,24+,25-,26+,27-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1 | Reactome pathway
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| Article
| n/a | n/a | 224 | n/a | n/a | n/a | n/a | 2.5 | 25 |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo... |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421354
(CHEMBL26966)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O |wU:48.53,12.12,wD:23.24,10.9,31.33,46.49,12.13,16.16,37.39,48.52,44.47,c:43,(-2.8,-3.98,;-2.77,-2.44,;-1.44,-1.68,;-1.44,-3.21,;-.13,-3.98,;-.13,-5.53,;1.22,-3.21,;2.56,-3.98,;1.22,-1.68,;2.53,-2.46,;3.87,-3.23,;3.87,-4.75,;5.2,-5.53,;3.84,-6.29,;6.53,-6.3,;6.53,-7.84,;6.53,-4.78,;7.86,-5.54,;6.53,-3.23,;7.89,-2.46,;5.2,-2.46,;2.56,-.91,;3.89,-1.68,;2.56,.65,;3.89,1.43,;5.22,2.2,;6.58,1.44,;7.89,2.21,;9.24,1.44,;7.89,3.76,;6.55,4.53,;5.22,3.76,;3.87,4.5,;6.55,6.07,;5.22,6.83,;7.89,6.84,;9.22,6.07,;1.22,1.4,;2.56,2.17,;1.22,2.95,;-.11,3.72,;-.13,5.26,;-1.44,2.95,;-.67,1.61,;-1.44,1.4,;-2.94,1.8,;-2.77,.63,;-4.32,.63,;-2.77,-.91,;-3.87,-2.01,;-4.32,-.91,)| Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 302 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421354
(CHEMBL26966)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O |wU:48.53,12.12,wD:23.24,10.9,31.33,46.49,12.13,16.16,37.39,48.52,44.47,c:43,(-2.8,-3.98,;-2.77,-2.44,;-1.44,-1.68,;-1.44,-3.21,;-.13,-3.98,;-.13,-5.53,;1.22,-3.21,;2.56,-3.98,;1.22,-1.68,;2.53,-2.46,;3.87,-3.23,;3.87,-4.75,;5.2,-5.53,;3.84,-6.29,;6.53,-6.3,;6.53,-7.84,;6.53,-4.78,;7.86,-5.54,;6.53,-3.23,;7.89,-2.46,;5.2,-2.46,;2.56,-.91,;3.89,-1.68,;2.56,.65,;3.89,1.43,;5.22,2.2,;6.58,1.44,;7.89,2.21,;9.24,1.44,;7.89,3.76,;6.55,4.53,;5.22,3.76,;3.87,4.5,;6.55,6.07,;5.22,6.83,;7.89,6.84,;9.22,6.07,;1.22,1.4,;2.56,2.17,;1.22,2.95,;-.11,3.72,;-.13,5.26,;-1.44,2.95,;-.67,1.61,;-1.44,1.4,;-2.94,1.8,;-2.77,.63,;-4.32,.63,;-2.77,-.91,;-3.87,-2.01,;-4.32,-.91,)| Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 302 | n/a | n/a | n/a | n/a | 2.5 | 25 |
TBA
Curated by ChEMBL
| Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo... |
Bioorg Med Chem Lett 4: 1347-1352 (1994)
Article DOI: 10.1016/S0960-894X(01)80359-0
BindingDB Entry DOI: 10.7270/Q2PR7X8T |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108836
(2-Amino-N-[2-(3,5-di-tert-butyl-4-hydroxy-benzyl)-...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)cc(c1O)C(C)(C)C Show InChI InChI=1S/C35H51N5O5/c1-34(2,3)24-18-23(19-25(30(24)42)35(4,5)6)21-28-32(44)38-17-15-29(41)37-16-11-10-14-27(33(45)40-28)39-31(43)26(36)20-22-12-8-7-9-13-22/h7-9,12-13,18-19,26-28,42H,10-11,14-17,20-21,36H2,1-6H3,(H,37,41)(H,38,44)(H,39,43)(H,40,45) | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108837
(2-Amino-N-[2-(4-sec-butoxy-benzyl)-3,7,14-trioxo-1...)Show SMILES CCC(C)Oc1ccc(CC2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)cc1 Show InChI InChI=1S/C31H43N5O5/c1-3-21(2)41-24-14-12-23(13-15-24)20-27-30(39)34-18-16-28(37)33-17-8-7-11-26(31(40)36-27)35-29(38)25(32)19-22-9-5-4-6-10-22/h4-6,9-10,12-15,21,25-27H,3,7-8,11,16-20,32H2,1-2H3,(H,33,37)(H,34,39)(H,35,38)(H,36,40) | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108828
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)[C@@H](N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C31H43N5O5/c1-31(2,3)22-17-21(12-13-26(22)37)19-25-29(40)34-16-14-27(38)33-15-8-7-11-24(30(41)36-25)35-28(39)23(32)18-20-9-5-4-6-10-20/h4-6,9-10,12-13,17,23-25,37H,7-8,11,14-16,18-19,32H2,1-3H3,(H,33,38)(H,34,40)(H,35,39)(H,36,41)/t23-,24?,25?/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108827
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)Show SMILES CC(C)(C)c1cc(CC2NC(=O)[C@H](CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C31H43N5O5/c1-31(2,3)22-17-21(12-13-26(22)37)19-25-29(40)34-16-14-27(38)33-15-8-7-11-24(30(41)36-25)35-28(39)23(32)18-20-9-5-4-6-10-20/h4-6,9-10,12-13,17,23-25,37H,7-8,11,14-16,18-19,32H2,1-3H3,(H,33,38)(H,34,40)(H,35,39)(H,36,41)/t23?,24-,25?/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108835
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)Show SMILES CC(C)(C)c1cc(C[C@H]2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O Show InChI InChI=1S/C31H43N5O5/c1-31(2,3)22-17-21(12-13-26(22)37)19-25-29(40)34-16-14-27(38)33-15-8-7-11-24(30(41)36-25)35-28(39)23(32)18-20-9-5-4-6-10-20/h4-6,9-10,12-13,17,23-25,37H,7-8,11,14-16,18-19,32H2,1-3H3,(H,33,38)(H,34,40)(H,35,39)(H,36,41)/t23?,24?,25-/m1/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108831
(2-Amino-N-[2-(4-tert-butoxy-benzyl)-3,7,14-trioxo-...)Show SMILES CC(C)(C)Oc1ccc(CC2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)cc1 Show InChI InChI=1S/C31H43N5O5/c1-31(2,3)41-23-14-12-22(13-15-23)20-26-29(39)34-18-16-27(37)33-17-8-7-11-25(30(40)36-26)35-28(38)24(32)19-21-9-5-4-6-10-21/h4-6,9-10,12-15,24-26H,7-8,11,16-20,32H2,1-3H3,(H,33,37)(H,34,39)(H,35,38)(H,36,40) | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108834
(2-Amino-N-[2-(4-hydroxy-benzyl)-3,7,14-trioxo-1,4,...)Show SMILES NC(Cc1ccccc1)C(=O)NC1CCCCNC(=O)CCNC(=O)C(Cc2ccc(O)cc2)NC1=O Show InChI InChI=1S/C27H35N5O5/c28-21(16-18-6-2-1-3-7-18)25(35)31-22-8-4-5-14-29-24(34)13-15-30-26(36)23(32-27(22)37)17-19-9-11-20(33)12-10-19/h1-3,6-7,9-12,21-23,33H,4-5,8,13-17,28H2,(H,29,34)(H,30,36)(H,31,35)(H,32,37) | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50108834
(2-Amino-N-[2-(4-hydroxy-benzyl)-3,7,14-trioxo-1,4,...)Show SMILES NC(Cc1ccccc1)C(=O)NC1CCCCNC(=O)CCNC(=O)C(Cc2ccc(O)cc2)NC1=O Show InChI InChI=1S/C27H35N5O5/c28-21(16-18-6-2-1-3-7-18)25(35)31-22-8-4-5-14-29-24(34)13-15-30-26(36)23(32-27(22)37)17-19-9-11-20(33)12-10-19/h1-3,6-7,9-12,21-23,33H,4-5,8,13-17,28H2,(H,29,34)(H,30,36)(H,31,35)(H,32,37) | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co. Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of the motilin receptor (MTL-R) |
J Med Chem 45: 670-5 (2002)
BindingDB Entry DOI: 10.7270/Q23B5ZF9 |
More data for this
Ligand-Target Pair | |
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