Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Homo sapiens (Human)) | BDBM50334788 ((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrate | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Homo sapiens (Human)) | BDBM91713 (Androst-4-en-3,17-dione, 2 | Androst-4-ene-3,17-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrate | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Homo sapiens (Human)) | BDBM50034508 ((10R,13S,17S)-4-Hydroxy-10,13-dimethyl-3-oxo-2,3,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 172 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrate | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Homo sapiens (Human)) | BDBM50034511 ((10R,13S,17S)-4-Chloro-10,13-dimethyl-3-oxo-2,3,6,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 192 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrate | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM50334788 ((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 218 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human Steroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Homo sapiens (Human)) | BDBM50034509 ((10R,13S,17S)-4-Bromo-10,13-dimethyl-3-oxo-2,3,6,7...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 387 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrate | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Homo sapiens (Human)) | BDBM50034507 ((10R,13S,17S)-4-Mercapto-10,13-dimethyl-3-oxo-2,3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 437 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrate | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM50034507 ((10R,13S,17S)-4-Mercapto-10,13-dimethyl-3-oxo-2,3,...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 709 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate. | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM50034509 ((10R,13S,17S)-4-Bromo-10,13-dimethyl-3-oxo-2,3,6,7...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 981 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate. | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM50034511 ((10R,13S,17S)-4-Chloro-10,13-dimethyl-3-oxo-2,3,6,...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate. | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM50034508 ((10R,13S,17S)-4-Hydroxy-10,13-dimethyl-3-oxo-2,3,6...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate. | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM91713 (Androst-4-en-3,17-dione, 2 | Androst-4-ene-3,17-di...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHUL Research Center Curated by ChEMBL | Assay Description In vitro inhibition of human tSteroid 5-alpha-reductase type I in transfected 293 cells using [3H]- delta4-Androstenedione as substrate. | J Med Chem 38: 1456-61 (1995) BindingDB Entry DOI: 10.7270/Q2W096K6 | |||||||||||
More data for this Ligand-Target Pair |