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Compile Data Set for Download or QSAR

Found 38 hits with Last Name = 'violitzi' and Initial = 'f'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50373071
PNG
(CHEMBL255489)
Show SMILES CN(CCN(C)Cc1coc2cc(C)c(C)cc2c1=O)Cc1cn(-c2cccc(c2)C(F)(F)F)c2ccccc12
Show InChI InChI=1S/C32H32F3N3O2/c1-21-14-28-30(15-22(21)2)40-20-24(31(28)39)18-37(4)13-12-36(3)17-23-19-38(29-11-6-5-10-27(23)29)26-9-7-8-25(16-26)32(33,34)35/h5-11,14-16,19-20H,12-13,17-18H2,1-4H3
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MCE
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PDB
UniChem
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547339
PNG
(CHEMBL4760595)
Show SMILES [O-][N+](=O)c1cccc(c1)S(=O)(=O)n1cc(C(=O)N2CCN(CC2)S(=O)(=O)c2ccccc2)c2ccccc12
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n/an/a 1.40E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547333
PNG
(CHEMBL3742191)
Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(-c2cccc(c2)[N+]([O-])=O)c2ccccc12
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n/an/a 1.88E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547338
PNG
(CHEMBL4797434)
Show SMILES CN(CCN(C)S(=O)(=O)c1cccc(c1)[N+]([O-])=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(c1)[N+]([O-])=O
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n/an/a 1.90E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547337
PNG
(CHEMBL4750116)
Show SMILES CN(CCN(C)S(=O)(=O)c1ccc(cc1)C#N)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(c1)[N+]([O-])=O
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n/an/a 2.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547332
PNG
(CHEMBL4756975)
Show SMILES CN(CCN(C)Cc1coc2ccccc2c1=O)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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n/an/a 2.50E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547336
PNG
(CHEMBL4745590)
Show SMILES CN(CCN(C)S(=O)(=O)c1ccccc1)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(c1)[N+]([O-])=O
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n/an/a 2.70E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547334
PNG
(CHEMBL3741720)
Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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n/an/a 2.86E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547335
PNG
(CHEMBL3741275)
Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(c1)[N+]([O-])=O
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n/an/a 5.07E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547340
PNG
(CHEMBL4752672)
Show SMILES [O-][N+](=O)c1cccc(c1)S(=O)(=O)n1cc(C(=O)N2CCN(CC2)S(=O)(=O)c2ccc(cc2)C#N)c2ccccc12
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n/an/a 5.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547341
PNG
(CHEMBL4745373)
Show SMILES [O-][N+](=O)c1cccc(c1)S(=O)(=O)N1CCN(CC1)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(c1)[N+]([O-])=O
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n/an/a 6.40E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547350
PNG
(CHEMBL3740948)
Show SMILES Nc1cccc(c1)-n1cc(C(=O)N2CCN(CC2)C(=O)c2coc3ccccc3c2=O)c2ccccc12
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n/an/an/a 1.91E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547334
PNG
(CHEMBL3741720)
Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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Article
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n/an/an/a 4.60E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547351
PNG
(CHEMBL3740702)
Show SMILES O=C(N1CCN(CC1)C(=O)c1coc2ccccc2c1=O)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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Article
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n/an/an/a 1.10E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547335
PNG
(CHEMBL3741275)
Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(c1)[N+]([O-])=O
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n/an/an/a 4.60E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547352
PNG
(CHEMBL3740051)
Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(N)c1
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n/an/an/a 2.23E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547353
PNG
(CHEMBL3741922)
Show SMILES O=C(NCCNC(=O)c1ccc2ccccc2c1)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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n/an/an/a 3.55E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547354
PNG
(CHEMBL3740629)
Show SMILES CN(CCN(C)C(=O)c1ccccc1)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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n/an/an/a>1.50E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547355
PNG
(CHEMBL3740630)
Show SMILES CN(CCN(C)C(=O)c1ccccc1F)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1
PDB

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Article
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n/an/an/a 1.25E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547356
PNG
(CHEMBL3742150)
Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(-c2cccc(c2)C(F)(F)F)c2ccc(cc12)[N+]([O-])=O
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n/an/an/a 2.82E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547357
PNG
(CHEMBL3741278)
Show SMILES Nc1cccc(c1)-n1cc(C(=O)N2CCN(CC2)C(=O)c2coc3ccccc3c2=O)c2cc(N)ccc12
PDB

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n/an/an/a 9.31E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547358
PNG
(CHEMBL3741437)
Show SMILES FC(F)(F)c1cccc(c1)-n1cc(C(=O)N2CCN(CC2)C(=O)n2ccnc2)c2ccccc12
PDB

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n/an/an/a 5.34E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547359
PNG
(CHEMBL3741883)
Show SMILES FC(F)(F)c1cccc(c1)-n1cc(CN2CCN(CC2)C(=O)c2coc3ccccc3c2=O)c2ccccc12
PDB

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n/an/an/a 8.49E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547360
PNG
(CHEMBL3741027)
Show SMILES FC(F)(F)c1cccc(c1)-n1cc(CN2CCN(CC2)C(=O)c2ccccc2)c2ccccc12
PDB

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n/an/an/a 1.86E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547361
PNG
(CHEMBL3740299)
Show SMILES O=C(NCCCCNC(=O)c1ccc2ccccc2c1)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1
PDB

UniProtKB/SwissProt

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n/an/an/a 1.84E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547362
PNG
(CHEMBL3740371)
Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)N3CCN(CC3)C(=O)c3ccccc3F)c2c1
PDB

UniProtKB/SwissProt

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n/an/an/a 1.28E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547349
PNG
(CHEMBL3740423)
Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(-c2cccc(N)c2)c2ccccc12
PDB

UniProtKB/SwissProt

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UniChem
Article
PubMed
n/an/an/a 1.76E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547348
PNG
(CHEMBL3741025)
Show SMILES [O-][N+](=O)c1cccc(c1)-n1cc(C(=O)N2CCN(CC2)C(=O)c2coc3ccccc3c2=O)c2ccccc12
PDB

UniProtKB/SwissProt

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n/an/an/a>2.50E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547333
PNG
(CHEMBL3742191)
Show SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(-c2cccc(c2)[N+]([O-])=O)c2ccccc12
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n/an/an/a 2.18E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547363
PNG
(CHEMBL3741962)
Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)N3CCN(CC3)C(=O)c3cccs3)c2c1
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n/an/an/a 1.58E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547346
PNG
(CHEMBL3741215)
Show SMILES Cc1ccc2occ(CN3CCN(Cc4cn(-c5cccc(c5)C(F)(F)F)c5ccccc45)CC3)c(=O)c2c1
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n/an/an/a>1.10E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547345
PNG
(CHEMBL3741761)
Show SMILES Cc1cc2occ(CN3CCN(Cc4cn(-c5cccc(c5)C(F)(F)F)c5ccccc45)CC3)c(=O)c2cc1C
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n/an/an/a>1.00E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547344
PNG
(CHEMBL4783826)
Show SMILES CN(CCN(C)Cc1coc2ccc(C)cc2c1=O)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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n/an/an/a 6.62E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547343
PNG
(CHEMBL4787527)
Show SMILES CN(CCN(C)Cc1coc2cc(C)ccc2c1=O)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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n/an/an/a 4.90E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547332
PNG
(CHEMBL4756975)
Show SMILES CN(CCN(C)Cc1coc2ccccc2c1=O)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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n/an/an/a 5.24E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547342
PNG
(CHEMBL4794699)
Show SMILES CN(CCN(C)Cc1coc2cc(C)c(C)cc2c1=O)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1
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n/an/an/a 8.71E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50373071
PNG
(CHEMBL255489)
Show SMILES CN(CCN(C)Cc1coc2cc(C)c(C)cc2c1=O)Cc1cn(-c2cccc(c2)C(F)(F)F)c2ccccc12
Show InChI InChI=1S/C32H32F3N3O2/c1-21-14-28-30(15-22(21)2)40-20-24(31(28)39)18-37(4)13-12-36(3)17-23-19-38(29-11-6-5-10-27(23)29)26-9-7-8-25(16-26)32(33,34)35/h5-11,14-16,19-20H,12-13,17-18H2,1-4H3
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CHEMBL
MCE
PC cid
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UniChem
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PubMed
n/an/an/a 1.38E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11


(Homo sapiens)		BDBM50547347
PNG
(CHEMBL3741778)
Show SMILES Cc1cc2occ(C(=O)N3CCN(CC3)C(=O)c3cn(-c4cccc(c4)C(F)(F)F)c4ccccc34)c(=O)c2cc1C
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n/an/an/a 4.60E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01316
BindingDB Entry DOI: 10.7270/Q2PZ5DDQ
More data for this
Ligand-Target Pair