Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transporter (Rattus norvegicus) | BDBM50020712 (10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of the NE [3H]-Norepinephrine uptake by rat brain slices In vitro | J Med Chem 27: 616-27 (1984) BindingDB Entry DOI: 10.7270/Q2NS0SX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50020712 (10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of [14C]-5-HT transporter uptake by rat brain slices | J Med Chem 27: 616-27 (1984) BindingDB Entry DOI: 10.7270/Q2NS0SX2 | |||||||||||
More data for this Ligand-Target Pair |