Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin B (Homo sapiens (Human)) | BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Whitman College Curated by ChEMBL | Assay Description Inhibition of human liver cathepsin B using Cbz-RR-AMC as substrate by fluorometric assay | ACS Med Chem Lett 7: 250-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00401 BindingDB Entry DOI: 10.7270/Q2222WPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Homo sapiens (Human)) | BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 653 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Whitman College Curated by ChEMBL | Assay Description Inhibition of m-calpain (unknown origin) using Suc-LY-AMC as substrate by fluorometric assay | ACS Med Chem Lett 7: 250-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00401 BindingDB Entry DOI: 10.7270/Q2222WPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Homo sapiens (Human)) | BDBM50169089 (CHEMBL3804980) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Whitman College Curated by ChEMBL | Assay Description Inhibition of m-calpain (unknown origin) using Suc-LY-AMC as substrate by fluorometric assay | ACS Med Chem Lett 7: 250-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00401 BindingDB Entry DOI: 10.7270/Q2222WPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Homo sapiens (Human)) | BDBM50169088 (CHEMBL3806032) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Whitman College Curated by ChEMBL | Assay Description Inhibition of m-calpain (unknown origin) using Suc-LY-AMC as substrate by fluorometric assay | ACS Med Chem Lett 7: 250-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00401 BindingDB Entry DOI: 10.7270/Q2222WPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50169089 (CHEMBL3804980) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Whitman College Curated by ChEMBL | Assay Description Inhibition of human liver cathepsin B using Cbz-RR-AMC as substrate by fluorometric assay | ACS Med Chem Lett 7: 250-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00401 BindingDB Entry DOI: 10.7270/Q2222WPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Homo sapiens (Human)) | BDBM50169087 (CHEMBL3805992) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Whitman College Curated by ChEMBL | Assay Description Inhibition of m-calpain (unknown origin) using Suc-LY-AMC as substrate by fluorometric assay | ACS Med Chem Lett 7: 250-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00401 BindingDB Entry DOI: 10.7270/Q2222WPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50169088 (CHEMBL3806032) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Whitman College Curated by ChEMBL | Assay Description Inhibition of human liver cathepsin B using Cbz-RR-AMC as substrate by fluorometric assay | ACS Med Chem Lett 7: 250-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00401 BindingDB Entry DOI: 10.7270/Q2222WPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50169087 (CHEMBL3805992) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Whitman College Curated by ChEMBL | Assay Description Inhibition of human liver cathepsin B using Cbz-RR-AMC as substrate by fluorometric assay | ACS Med Chem Lett 7: 250-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00401 BindingDB Entry DOI: 10.7270/Q2222WPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arylamine N-acetyltransferase (Mycobacterium smegmatis) | BDBM50336284 (3-[3'-(2''cyclopent-2'''-en-1'''-ylphenoxy)-2'-hyd...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis NAT using isoniazed substrate by acetyl-coA hydrolysis assay | Bioorg Med Chem Lett 21: 1185-90 (2011) Article DOI: 10.1016/j.bmcl.2010.12.099 BindingDB Entry DOI: 10.7270/Q2SJ1KWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arylamine N-acetyltransferase (Pseudomonas aeruginosa) | BDBM50336284 (3-[3'-(2''cyclopent-2'''-en-1'''-ylphenoxy)-2'-hyd...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.62E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa NAT using 5-aminosalicylate substrate by acetyl-coA hydrolysis assay | Bioorg Med Chem Lett 21: 1185-90 (2011) Article DOI: 10.1016/j.bmcl.2010.12.099 BindingDB Entry DOI: 10.7270/Q2SJ1KWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arylamine N-acetyltransferase (Mycobacterium smegmatis) | BDBM50336284 (3-[3'-(2''cyclopent-2'''-en-1'''-ylphenoxy)-2'-hyd...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis NAT using 5-aminosalicylate substrate by acetyl-coA hydrolysis assay | Bioorg Med Chem Lett 21: 1185-90 (2011) Article DOI: 10.1016/j.bmcl.2010.12.099 BindingDB Entry DOI: 10.7270/Q2SJ1KWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arylamine N-acetyltransferase (Pseudomonas aeruginosa) | BDBM50336284 (3-[3'-(2''cyclopent-2'''-en-1'''-ylphenoxy)-2'-hyd...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa NAT using isoniazed substrate by acetyl-coA hydrolysis assay | Bioorg Med Chem Lett 21: 1185-90 (2011) Article DOI: 10.1016/j.bmcl.2010.12.099 BindingDB Entry DOI: 10.7270/Q2SJ1KWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arylamine N-acetyltransferase (Mycobacterium smegmatis) | BDBM50336283 (3-[3'-(4-cyclopent-2'''-en-1'''-ylphenoxy)-2'-hydr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis NAT using isoniazed substrate by acetyl-coA hydrolysis assay | Bioorg Med Chem Lett 21: 1185-90 (2011) Article DOI: 10.1016/j.bmcl.2010.12.099 BindingDB Entry DOI: 10.7270/Q2SJ1KWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arylamine N-acetyltransferase (Pseudomonas aeruginosa) | BDBM50336283 (3-[3'-(4-cyclopent-2'''-en-1'''-ylphenoxy)-2'-hydr...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa NAT using isoniazed substrate by acetyl-coA hydrolysis assay | Bioorg Med Chem Lett 21: 1185-90 (2011) Article DOI: 10.1016/j.bmcl.2010.12.099 BindingDB Entry DOI: 10.7270/Q2SJ1KWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arylamine N-acetyltransferase (Pseudomonas aeruginosa) | BDBM50336283 (3-[3'-(4-cyclopent-2'''-en-1'''-ylphenoxy)-2'-hydr...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa NAT using 5-aminosalicylate substrate by acetyl-coA hydrolysis assay | Bioorg Med Chem Lett 21: 1185-90 (2011) Article DOI: 10.1016/j.bmcl.2010.12.099 BindingDB Entry DOI: 10.7270/Q2SJ1KWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arylamine N-acetyltransferase (Mycobacterium smegmatis) | BDBM50336283 (3-[3'-(4-cyclopent-2'''-en-1'''-ylphenoxy)-2'-hydr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis NAT using 5-aminosalicylate substrate by acetyl-coA hydrolysis assay | Bioorg Med Chem Lett 21: 1185-90 (2011) Article DOI: 10.1016/j.bmcl.2010.12.099 BindingDB Entry DOI: 10.7270/Q2SJ1KWB | |||||||||||
More data for this Ligand-Target Pair |