Found 10 hits with Last Name = 'yoo' and Initial = 'jl' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50049730
(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)Show InChI InChI=1S/C15H13NO3S2/c1-10(7-11-5-3-2-4-6-11)8-12-14(19)16(9-13(17)18)15(20)21-12/h2-8H,9H2,1H3,(H,17,18)/b10-7+,12-8- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM84978
(Quercitrin | cid_5280459)Show SMILES C[C@@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O Show InChI InChI=1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-24,26-29H,1H3/t7-,15-,17+,18+,21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| KEGG MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50241345
(Apigenin 7-O-β-D-glucuronide (9) | CHEMBL2542...)Show SMILES O[C@H]1[C@H](Oc2cc(O)c3c(c2)oc(cc3=O)-c2ccc(O)cc2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O |r| Show InChI InChI=1S/C21H18O11/c22-9-3-1-8(2-4-9)13-7-12(24)15-11(23)5-10(6-14(15)31-13)30-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21-23,25-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM7462
(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)Show InChI InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM7459
(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)Show InChI InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50241243
(3,4',5,7-Tetrahydroxyflavone-3-glucoside | 3-(beta...)Show SMILES OC[C@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-24,26-29H,7H2/t13-,15-,17+,18-,21+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM7458
(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM7460
(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)Show InChI InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50251270
(CHEMBL464868 | apigenin-7-O-beta-D-glucuronide met...)Show SMILES COC(=O)[C@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(cc3=O)-c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C22H20O11/c1-30-21(29)20-18(27)17(26)19(28)22(33-20)31-11-6-12(24)16-13(25)8-14(32-15(16)7-11)9-2-4-10(23)5-3-9/h2-8,17-20,22-24,26-28H,1H3/t17-,18-,19+,20-,22+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50251269
(CHEMBL465526 | rel-(2R,3R)-3,5,7,3',4'-pentahydrox...)Show SMILES COC(=O)C[C@]1(O)C(=O)c2c(O)cc(O)cc2O[C@]1(OC)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C19H18O10/c1-27-15(24)8-18(26)17(25)16-13(23)6-10(20)7-14(16)29-19(18,28-2)9-3-4-11(21)12(22)5-9/h3-7,20-23,26H,8H2,1-2H3/t18-,19+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Oriental Medicine
Curated by ChEMBL
| Assay Description Inhibition of rat lens aldose reductase |
J Nat Prod 71: 713-5 (2008)
Article DOI: 10.1021/np070489a BindingDB Entry DOI: 10.7270/Q2RN38SR |
More data for this Ligand-Target Pair | |