Compile Data Set for Download or QSAR

Found 62 hits with Last Name = 'zazzi' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540801 (CHEMBL4633761) Show SMILES CCOCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1cccc(c1)C(=O)OCC Show InChI InChI=1S/C20H22N4O5S/c1-3-28-14-17-13-24(23-21-17)18-9-6-10-19(12-18)30(26,27)22-16-8-5-7-15(11-16)20(25)29-4-2/h5-13,22H,3-4,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM25351 (N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...) Show SMILES Cc1nnc(o1)C(=O)NC(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C Show InChI InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
IRBM S.p.A. Curated by ChEMBL					Assay Description Inhibition of wild type recombinant HIV1 His6-tagged integrase expressed in Escherichia coli BL21 using 18 nucleotide 3'-biotin labeled DNA acceptor ...				ACS Med Chem Lett 11: 766-772 (2020) Article DOI: 10.1021/acsmedchemlett.9b00608 BindingDB Entry DOI: 10.7270/Q2XS5ZZZ
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540794 (CHEMBL4633565) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2NS(C)(=O)=O)cc1 Show InChI InChI=1S/C20H24N6O3S/c1-3-4-7-16-14-26(25-23-16)17-12-10-15(11-13-17)21-20(27)22-18-8-5-6-9-19(18)24-30(2,28)29/h5-6,8-14,24H,3-4,7H2,1-2H3,(H2,21,22,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540800 (CHEMBL4642739) Show SMILES CCOCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1N1CCOCC1 Show InChI InChI=1S/C21H25N5O4S/c1-2-29-16-17-15-26(24-22-17)18-6-5-7-19(14-18)31(27,28)23-20-8-3-4-9-21(20)25-10-12-30-13-11-25/h3-9,14-15,23H,2,10-13,16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540802 (CHEMBL4644016) Show SMILES CCOCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1NS(C)(=O)=O Show InChI InChI=1S/C18H21N5O5S2/c1-3-28-13-14-12-23(22-19-14)15-7-6-8-16(11-15)30(26,27)21-18-10-5-4-9-17(18)20-29(2,24)25/h4-12,20-21H,3,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552035 (CHEMBL4792698) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cc(OC3CCOC3)ccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552040 (CHEMBL4764675) Show SMILES CC(C)CCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc3cnccc23)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50537055 (CHEMBL4591917) Show SMILES CCCCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1cccc2cnccc12 Show InChI InChI=1S/C21H21N5O2S/c1-2-3-7-17-15-26(25-23-17)18-8-5-9-19(13-18)29(27,28)24-21-10-4-6-16-14-22-12-11-20(16)21/h4-6,8-15,24H,2-3,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540786 (CHEMBL4634423) Show SMILES CC(C)CCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2F)cc1 Show InChI InChI=1S/C20H22FN5O/c1-14(2)7-8-16-13-26(25-24-16)17-11-9-15(10-12-17)22-20(27)23-19-6-4-3-5-18(19)21/h3-6,9-14H,7-8H2,1-2H3,(H2,22,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552034 (CHEMBL4743218) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cc(OC3CCCC3)ccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552041 (CHEMBL4744776) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc3cnccc23)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540798 (CHEMBL4639795) Show SMILES CC(C)CCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C)cc1 Show InChI InChI=1S/C21H25N5O/c1-15(2)8-9-18-14-26(25-24-18)19-12-10-17(11-13-19)22-21(27)23-20-7-5-4-6-16(20)3/h4-7,10-15H,8-9H2,1-3H3,(H2,22,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540785 (CHEMBL4577525) Show SMILES CCCCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1OC Show InChI InChI=1S/C19H22N4O3S/c1-3-4-8-15-14-23(22-20-15)16-9-7-10-17(13-16)27(24,25)21-18-11-5-6-12-19(18)26-2/h5-7,9-14,21H,3-4,8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540787 (CHEMBL4648145) Show SMILES CC(C)CCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 Show InChI InChI=1S/C20H22FN5O/c1-14(2)6-7-18-13-26(25-24-18)19-10-8-16(9-11-19)22-20(27)23-17-5-3-4-15(21)12-17/h3-5,8-14H,6-7H2,1-2H3,(H2,22,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540793 (CHEMBL4635553) Show SMILES COc1cc(NC(=O)Nc2ccccc2C(F)(F)F)ccc1-n1cc(CCC(C)C)nn1 Show InChI InChI=1S/C22H24F3N5O2/c1-14(2)8-9-16-13-30(29-28-16)19-11-10-15(12-20(19)32-3)26-21(31)27-18-7-5-4-6-17(18)22(23,24)25/h4-7,10-14H,8-9H2,1-3H3,(H2,26,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540799 (CHEMBL4635666) Show SMILES CCCCCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C22H24F3N5O/c1-2-3-4-5-8-17-15-30(29-28-17)18-13-11-16(12-14-18)26-21(31)27-20-10-7-6-9-19(20)22(23,24)25/h6-7,9-15H,2-5,8H2,1H3,(H2,26,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50537058 (CHEMBL4531719) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C)cc1 Show InChI InChI=1S/C20H23N5O/c1-3-4-8-17-14-25(24-23-17)18-12-10-16(11-13-18)21-20(26)22-19-9-6-5-7-15(19)2/h5-7,9-14H,3-4,8H2,1-2H3,(H2,21,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50537058 (CHEMBL4531719) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C)cc1 Show InChI InChI=1S/C20H23N5O/c1-3-4-8-17-14-25(24-23-17)18-12-10-16(11-13-18)21-20(26)22-19-9-6-5-7-15(19)2/h5-7,9-14H,3-4,8H2,1-2H3,(H2,21,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50537056 (CHEMBL4571759) Show SMILES CCCCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1C(F)(F)F Show InChI InChI=1S/C19H19F3N4O2S/c1-2-3-7-14-13-26(25-23-14)15-8-6-9-16(12-15)29(27,28)24-18-11-5-4-10-17(18)19(20,21)22/h4-6,8-13,24H,2-3,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540784 (CHEMBL4533005) Show SMILES CCCCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1O Show InChI InChI=1S/C18H20N4O3S/c1-2-3-7-14-13-22(21-19-14)15-8-6-9-16(12-15)26(24,25)20-17-10-4-5-11-18(17)23/h4-6,8-13,20,23H,2-3,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540783 (CHEMBL4569026) Show SMILES CCOCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1C(F)(F)F Show InChI InChI=1S/C18H17F3N4O3S/c1-2-28-12-13-11-25(24-22-13)14-6-5-7-15(10-14)29(26,27)23-17-9-4-3-8-16(17)18(19,20)21/h3-11,23H,2,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552022 (CHEMBL4785115) Show SMILES CC(C)CC(=O)OCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552031 (CHEMBL4741968) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cc(O)ccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540790 (CHEMBL4640027) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 Show InChI InChI=1S/C19H20FN5O/c1-2-3-6-17-13-25(24-23-17)18-10-8-15(9-11-18)21-19(26)22-16-7-4-5-14(20)12-16/h4-5,7-13H,2-3,6H2,1H3,(H2,21,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552032 (CHEMBL4742331) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cc(OCOC)ccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552024 (CHEMBL4741684) Show SMILES CCOP(=O)(OCC)OCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552033 (CHEMBL4787707) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cc(OP(=O)(OCC)OCC)ccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552037 (CHEMBL4784714) Show SMILES COCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540792 (CHEMBL4632918) Show SMILES COc1cc(ccc1NC(=O)Nc1ccccc1C(F)(F)F)-n1cc(CCC(C)C)nn1 Show InChI InChI=1S/C22H24F3N5O2/c1-14(2)8-9-15-13-30(29-28-15)16-10-11-19(20(12-16)32-3)27-21(31)26-18-7-5-4-6-17(18)22(23,24)25/h4-7,10-14H,8-9H2,1-3H3,(H2,26,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540797 (CHEMBL4649465) Show SMILES CCCC(C)C(F)c1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C22H23F4N5O/c1-3-6-14(2)20(23)19-13-31(30-29-19)16-11-9-15(10-12-16)27-21(32)28-18-8-5-4-7-17(18)22(24,25)26/h4-5,7-14,20H,3,6H2,1-2H3,(H2,27,28,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552023 (CHEMBL4799050) Show SMILES CC(C)CC(=O)OCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552038 (CHEMBL4790390) Show SMILES CCOCc1cn(nn1)-c1ccc(NC(=O)Nc2cc(ccc2C)C(C)C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540791 (CHEMBL4641139) Show SMILES CC(C)CCc1cn(nn1)-c1ccc(NC(=O)Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C20H22FN5O/c1-14(2)3-6-18-13-26(25-24-18)19-11-9-17(10-12-19)23-20(27)22-16-7-4-15(21)5-8-16/h4-5,7-14H,3,6H2,1-2H3,(H2,22,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552039 (CHEMBL4795681) Show SMILES CCOC(=O)CCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540795 (CHEMBL4646961) Show SMILES FCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C17H13F4N5O/c18-9-12-10-26(25-24-12)13-7-5-11(6-8-13)22-16(27)23-15-4-2-1-3-14(15)17(19,20)21/h1-8,10H,9H2,(H2,22,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540789 (CHEMBL4637516) Show SMILES CC(=O)CCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 Show InChI InChI=1S/C19H18FN5O2/c1-13(26)5-6-17-12-25(24-23-17)18-9-7-15(8-10-18)21-19(27)22-16-4-2-3-14(20)11-16/h2-4,7-12H,5-6H2,1H3,(H2,21,22,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552036 (CHEMBL4761720) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cc(CCC(C)=O)ccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552027 (CHEMBL4742051) Show SMILES CN(C)CCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552021 (CHEMBL4764209) Show SMILES FC(F)(F)c1ccccc1NC(=O)Nc1ccc(cc1)-n1cc(CCOC(=O)\C=C\c2ccc3OCOc3c2)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540796 (CHEMBL4638774) Show SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-n1cc(nn1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F Show InChI InChI=1S/C20H14F9N5O/c1-11-4-2-3-5-14(11)31-16(35)30-12-6-8-13(9-7-12)34-10-15(32-33-34)17(21,22)18(23,24)19(25,26)20(27,28)29/h2-10H,1H3,(H2,30,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552025 (CHEMBL4786545) Show SMILES OCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50552026 (CHEMBL4783844) Show SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-n1cc(CCO)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DDX3X using dsRNA as substrate measured every 30 sec for 40 mins by FRET assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112319 BindingDB Entry DOI: 10.7270/Q23J3HMG
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540788 (CHEMBL4637885) Show SMILES CCOCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 Show InChI InChI=1S/C18H18FN5O2/c1-2-26-12-16-11-24(23-22-16)17-8-6-14(7-9-17)20-18(25)21-15-5-3-4-13(19)10-15/h3-11H,2,12H2,1H3,(H2,20,21,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020) Article DOI: 10.1021/acsmedchemlett.9b00681 BindingDB Entry DOI: 10.7270/Q2N87FBS
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50540671 (CHEMBL4635907) Show SMILES C[C@@H](NC(=O)c1nc(nc(O)c1O)-c1nccc2ccccc12)C1CCCCC1 |r| Show InChI InChI=1S/C22H24N4O3/c1-13(14-7-3-2-4-8-14)24-21(28)18-19(27)22(29)26-20(25-18)17-16-10-6-5-9-15(16)11-12-23-17/h5-6,9-14,27H,2-4,7-8H2,1H3,(H,24,28)(H,25,26,29)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IRBM S.p.A. Curated by ChEMBL					Assay Description Inhibition of human microsomal CYP3A4 expressed in baculovirus infected insect cells using luciferin-IPA as substrate preincubated with enzyme/substr...				ACS Med Chem Lett 11: 766-772 (2020) Article DOI: 10.1021/acsmedchemlett.9b00608 BindingDB Entry DOI: 10.7270/Q2XS5ZZZ
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50540669 (CHEMBL4637524) Show SMILES COc1ccnc(c1)-c1nc(O)c(O)c(n1)C(=O)N[C@H](C)C1CCCCC1 |r| Show InChI InChI=1S/C19H24N4O4/c1-11(12-6-4-3-5-7-12)21-18(25)15-16(24)19(26)23-17(22-15)14-10-13(27-2)8-9-20-14/h8-12,24H,3-7H2,1-2H3,(H,21,25)(H,22,23,26)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IRBM S.p.A. Curated by ChEMBL					Assay Description Inhibition of human microsomal CYP1A2 expressed in baculovirus infected insect cells using luciferin-1A2 as substrate preincubated with enzyme-substr...				ACS Med Chem Lett 11: 766-772 (2020) Article DOI: 10.1021/acsmedchemlett.9b00608 BindingDB Entry DOI: 10.7270/Q2XS5ZZZ
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50540670 (CHEMBL4633550) Show SMILES C[C@@H](NC(=O)c1nc(nc(O)c1O)-c1cc(Cl)ccn1)C1CCCCC1 |r| Show InChI InChI=1S/C18H21ClN4O3/c1-10(11-5-3-2-4-6-11)21-17(25)14-15(24)18(26)23-16(22-14)13-9-12(19)7-8-20-13/h7-11,24H,2-6H2,1H3,(H,21,25)(H,22,23,26)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IRBM S.p.A. Curated by ChEMBL					Assay Description Inhibition of human microsomal CYP1A2 expressed in baculovirus infected insect cells using luciferin-1A2 as substrate preincubated with enzyme-substr...				ACS Med Chem Lett 11: 766-772 (2020) Article DOI: 10.1021/acsmedchemlett.9b00608 BindingDB Entry DOI: 10.7270/Q2XS5ZZZ
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50540668 (CHEMBL4637717) Show SMILES C[C@@H](NC(=O)c1nc(nc(O)c1O)-c1cc(ccn1)C(F)(F)F)C1CCCCC1 |r| Show InChI InChI=1S/C19H21F3N4O3/c1-10(11-5-3-2-4-6-11)24-17(28)14-15(27)18(29)26-16(25-14)13-9-12(7-8-23-13)19(20,21)22/h7-11,27H,2-6H2,1H3,(H,24,28)(H,25,26,29)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IRBM S.p.A. Curated by ChEMBL					Assay Description Inhibition of human microsomal CYP1A2 expressed in baculovirus infected insect cells using luciferin-1A2 as substrate preincubated with enzyme-substr...				ACS Med Chem Lett 11: 766-772 (2020) Article DOI: 10.1021/acsmedchemlett.9b00608 BindingDB Entry DOI: 10.7270/Q2XS5ZZZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50540671 (CHEMBL4635907) Show SMILES C[C@@H](NC(=O)c1nc(nc(O)c1O)-c1nccc2ccccc12)C1CCCCC1 |r| Show InChI InChI=1S/C22H24N4O3/c1-13(14-7-3-2-4-8-14)24-21(28)18-19(27)22(29)26-20(25-18)17-16-10-6-5-9-15(16)11-12-23-17/h5-6,9-14,27H,2-4,7-8H2,1H3,(H,24,28)(H,25,26,29)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IRBM S.p.A. Curated by ChEMBL					Assay Description Displacement of Tracer Red from human ERG measured after 4 hrs by fluorescence polarization assay				ACS Med Chem Lett 11: 766-772 (2020) Article DOI: 10.1021/acsmedchemlett.9b00608 BindingDB Entry DOI: 10.7270/Q2XS5ZZZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50540670 (CHEMBL4633550) Show SMILES C[C@@H](NC(=O)c1nc(nc(O)c1O)-c1cc(Cl)ccn1)C1CCCCC1 |r| Show InChI InChI=1S/C18H21ClN4O3/c1-10(11-5-3-2-4-6-11)21-17(25)14-15(24)18(26)23-16(22-14)13-9-12(19)7-8-20-13/h7-11,24H,2-6H2,1H3,(H,21,25)(H,22,23,26)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IRBM S.p.A. Curated by ChEMBL					Assay Description Displacement of Tracer Red from human ERG measured after 4 hrs by fluorescence polarization assay				ACS Med Chem Lett 11: 766-772 (2020) Article DOI: 10.1021/acsmedchemlett.9b00608 BindingDB Entry DOI: 10.7270/Q2XS5ZZZ
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50540671 (CHEMBL4635907) Show SMILES C[C@@H](NC(=O)c1nc(nc(O)c1O)-c1nccc2ccccc12)C1CCCCC1 |r| Show InChI InChI=1S/C22H24N4O3/c1-13(14-7-3-2-4-8-14)24-21(28)18-19(27)22(29)26-20(25-18)17-16-10-6-5-9-15(16)11-12-23-17/h5-6,9-14,27H,2-4,7-8H2,1H3,(H,24,28)(H,25,26,29)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IRBM S.p.A. Curated by ChEMBL					Assay Description Inhibition of human microsomal CYP1A2 expressed in baculovirus infected insect cells using luciferin-1A2 as substrate preincubated with enzyme-substr...				ACS Med Chem Lett 11: 766-772 (2020) Article DOI: 10.1021/acsmedchemlett.9b00608 BindingDB Entry DOI: 10.7270/Q2XS5ZZZ
					More data for this Ligand-Target Pair

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