Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM16312 ((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Aristotle University of Thessaloniki Curated by ChEMBL | Assay Description In vitro inhibitory activity of compound against rat lens aldose reductase | J Med Chem 47: 2706-9 (2004) Article DOI: 10.1021/jm031060t BindingDB Entry DOI: 10.7270/Q2NZ8720 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50146186 (CHEMBL329563 | [1-(3-Amino-5-fluoro-4-hydroxy-phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 396 | n/a | n/a | n/a | n/a | n/a | n/a |
Aristotle University of Thessaloniki Curated by ChEMBL | Assay Description In vitro inhibitory activity of compound against rat lens aldose reductase | J Med Chem 47: 2706-9 (2004) Article DOI: 10.1021/jm031060t BindingDB Entry DOI: 10.7270/Q2NZ8720 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50146187 ((3-Benzoyl-pyrrol-1-yl)-acetic acid | 2-(3-benzoyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Aristotle University of Thessaloniki Curated by ChEMBL | Assay Description In vitro inhibitory activity of compound against rat lens aldose reductase | J Med Chem 47: 2706-9 (2004) Article DOI: 10.1021/jm031060t BindingDB Entry DOI: 10.7270/Q2NZ8720 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50146185 (2-Amino-6-fluoro-4-pyrrol-1-yl-phenol | CHEMBL9423...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Aristotle University of Thessaloniki Curated by ChEMBL | Assay Description In vitro inhibitory activity of compound against rat lens aldose reductase | J Med Chem 47: 2706-9 (2004) Article DOI: 10.1021/jm031060t BindingDB Entry DOI: 10.7270/Q2NZ8720 | |||||||||||
More data for this Ligand-Target Pair |