Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ornithine aminotransferase, mitochondrial (Homo sapiens (Human)) | BDBM50121376 (GABACULINE) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hebrew University-Hadassah Medical Center Curated by ChEMBL | Assay Description Inhibition of human recombinant OAT using 1 mM alpha-ketoglutarate as substrate | ACS Med Chem Lett 6: 840-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00153 BindingDB Entry DOI: 10.7270/Q2TQ63B9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Ornithine aminotransferase, mitochondrial (Homo sapiens (Human)) | BDBM50199989 ((1S,3S)-3-amino-4-(2,2,2-trifluoro-1-trifluorometh...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hebrew University-Hadassah Medical Center Curated by ChEMBL | Assay Description Inhibition of human recombinant OAT using 1 mM alpha-ketoglutarate as substrate | ACS Med Chem Lett 6: 840-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00153 BindingDB Entry DOI: 10.7270/Q2TQ63B9 | |||||||||||
More data for this Ligand-Target Pair |