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There are 9 purchasable compounds for target: QP-C

Wt: 300.3
BDBM60397
Purchase
Wt: 277.3
BDBM50027959
Purchase
Wt: 305.3
BDBM50027960
Purchase
Wt: 355.4
BDBM50027961
Purchase
Wt: 305.3
BDBM50028005
Purchase
Wt: 305.3
BDBM50028006
Purchase
Wt: 263.3
BDBM50027958
Purchase
Wt: 325.3
BDBM50027963
Purchase
Wt: 299.3
BDBM50028007
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 60397,50027959,50027960,50027961,50028005,50028006,50027958,50027963,50028007   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome b-c1 complex subunit 7


(Homo sapiens (Human))
BDBM50027958
PNG
(CHEMBL3360255)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(O)cc1
Show InChI InChI=1S/C13H13NO3S/c1-10-2-8-13(9-3-10)18(16,17)14-11-4-6-12(15)7-5-11/h2-9,14-15H,1H3
PDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens (Human))
BDBM50027959
PNG
(CHEMBL3360256)
Show SMILES CCc1ccc(cc1)S(=O)(=O)Nc1ccc(O)cc1
Show InChI InChI=1S/C14H15NO3S/c1-2-11-3-9-14(10-4-11)19(17,18)15-12-5-7-13(16)8-6-12/h3-10,15-16H,2H2,1H3
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens (Human))
BDBM50027960
PNG
(CHEMBL188279)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(O)cc1
Show InChI InChI=1S/C16H19NO3S/c1-16(2,3)12-4-10-15(11-5-12)21(19,20)17-13-6-8-14(18)9-7-13/h4-11,17-18H,1-3H3
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens (Human))
BDBM50027961
PNG
(CHEMBL3360257)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(O)c2ccccc12
Show InChI InChI=1S/C20H21NO3S/c1-20(2,3)14-8-10-15(11-9-14)25(23,24)21-18-12-13-19(22)17-7-5-4-6-16(17)18/h4-13,21-22H,1-3H3
PDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens (Human))
BDBM50028007
PNG
(CHEMBL3360266)
Show SMILES Oc1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C16H13NO3S/c18-15-8-6-14(7-9-15)17-21(19,20)16-10-5-12-3-1-2-4-13(12)11-16/h1-11,17-18H
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens (Human))
BDBM50028005
PNG
(CHEMBL185823)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1cccc(O)c1
Show InChI InChI=1S/C16H19NO3S/c1-16(2,3)12-7-9-15(10-8-12)21(19,20)17-13-5-4-6-14(18)11-13/h4-11,17-18H,1-3H3
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens (Human))
BDBM50028006
PNG
(CHEMBL186268)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccccc1O
Show InChI InChI=1S/C16H19NO3S/c1-16(2,3)12-8-10-13(11-9-12)21(19,20)17-14-6-4-5-7-15(14)18/h4-11,17-18H,1-3H3
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens (Human))
BDBM60397
PNG
(MLS000115777 | N-(4-hydroxyphenyl)-8-quinolinesulf...)
Show SMILES Oc1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1
Show InChI InChI=1S/C15H12N2O3S/c18-13-8-6-12(7-9-13)17-21(19,20)14-5-1-3-11-4-2-10-16-15(11)14/h1-10,17-18H
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens (Human))
BDBM50027963
PNG
(CHEMBL3360259)
Show SMILES Oc1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)cc1
Show InChI InChI=1S/C18H15NO3S/c20-17-10-8-16(9-11-17)19-23(21,22)18-12-6-15(7-13-18)14-4-2-1-3-5-14/h1-13,19-20H
PDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
More data for this
Ligand-Target Pair