Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50197784
(1-[(E)-({5-bromo-2-[(2-methoxy-5-nitrophenyl)metho...)Show SMILES [#6]-[#8]-c1ccc(cc1-[#6]-[#8]-c1ccc(Br)cc1-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])-[#7+](-[#8-])=O |w:17.18| Show InChI InChI=1S/C16H16BrN5O4/c1-25-14-5-3-13(22(23)24)7-11(14)9-26-15-4-2-12(17)6-10(15)8-20-21-16(18)19/h2-8H,9H2,1H3,(H4,18,19,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP1alpha from human CCR5/CD4 expressed in HEK293 cells |
Bioorg Med Chem Lett 17: 231-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.09.052
BindingDB Entry DOI: 10.7270/Q2FQ9W8N |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50197784
(1-[(E)-({5-bromo-2-[(2-methoxy-5-nitrophenyl)metho...)Show SMILES [#6]-[#8]-c1ccc(cc1-[#6]-[#8]-c1ccc(Br)cc1-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])-[#7+](-[#8-])=O |w:17.18| Show InChI InChI=1S/C16H16BrN5O4/c1-25-14-5-3-13(22(23)24)7-11(14)9-26-15-4-2-12(17)6-10(15)8-20-21-16(18)19/h2-8H,9H2,1H3,(H4,18,19,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Antagonist activity at Homo sapiens (human) CCR5 receptor |
Citation and Details
Article DOI: 10.1007/s00044-012-0118-7
BindingDB Entry DOI: 10.7270/Q24J0J1F |
More data for this
Ligand-Target Pair | |