Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 543.1 BDBM50062979

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50062979 (CHEMBL3398000) Show SMILES C[C@H]1CN(Cc2ccc(F)cc2)CCN1CCCN(C(=O)C1CCN(CC1)C(C)=O)c1ccc(C)c(Cl)c1 |r| Show InChI InChI=1S/C30H40ClFN4O2/c1-22-5-10-28(19-29(22)31)36(30(38)26-11-15-35(16-12-26)24(3)37)14-4-13-34-18-17-33(20-23(34)2)21-25-6-8-27(32)9-7-25/h5-10,19,23,26H,4,11-18,20-21H2,1-3H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity against CCR5 (unknown origin) expressed in CHO cells co-expressing Galpha16 incubated for 10 mins assessed as inhibition of RANTE...				Bioorg Med Chem 23: 1157-68 (2015) Article DOI: 10.1016/j.bmc.2014.12.052 BindingDB Entry DOI: 10.7270/Q2WH2RN7
					More data for this Ligand-Target Pair