Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 553.1 BDBM50445434

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50445434 (CHEMBL3104688) Show SMILES CC(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(CC1)C(=O)NCCc1ccccc1)c1cccc(Cl)c1 Show InChI InChI=1S/C31H41ClN4O3/c1-24(37)35-21-14-27(15-22-35)31(39)36(29-10-5-9-28(32)23-29)18-6-17-34-19-12-26(13-20-34)30(38)33-16-11-25-7-3-2-4-8-25/h2-5,7-10,23,26-27H,6,11-22H2,1H3,(H,33,38)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...				Eur J Med Chem 71: 259-66 (2014) Article DOI: 10.1016/j.ejmech.2013.11.013 BindingDB Entry DOI: 10.7270/Q29G5P9F
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