Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 573.5 BDBM50445438

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50445438 (CHEMBL3104684) Show SMILES CC(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(CC1)C(=O)NCc1ccc(Cl)cc1)c1cccc(Cl)c1 Show InChI InChI=1S/C30H38Cl2N4O3/c1-22(37)35-18-12-25(13-19-35)30(39)36(28-5-2-4-27(32)20-28)15-3-14-34-16-10-24(11-17-34)29(38)33-21-23-6-8-26(31)9-7-23/h2,4-9,20,24-25H,3,10-19,21H2,1H3,(H,33,38)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...				Eur J Med Chem 71: 259-66 (2014) Article DOI: 10.1016/j.ejmech.2013.11.013 BindingDB Entry DOI: 10.7270/Q29G5P9F
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