Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50331647
(5-(4-(2-(4-(1-allyl-3-(4-(methylsulfonyl)phenyl)ur...)Show SMILES CC(C)(C)NS(=O)(=O)c1cc(C(=O)N2CCC(CCN3CCC(CC3)N(CC=C)C(=O)Nc3ccc(cc3)S(C)(=O)=O)(CC2)c2cccc(F)c2)c(Cl)cc1F Show InChI InChI=1S/C40H50ClF2N5O6S2/c1-6-19-48(38(50)44-30-10-12-32(13-11-30)55(5,51)52)31-14-20-46(21-15-31)22-16-40(28-8-7-9-29(42)25-28)17-23-47(24-18-40)37(49)33-26-36(35(43)27-34(33)41)56(53,54)45-39(2,3)4/h6-13,25-27,31,45H,1,14-24H2,2-5H3,(H,44,50) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infection |
Bioorg Med Chem Lett 20: 7397-400 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.033
BindingDB Entry DOI: 10.7270/Q27081P6 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50331647
(5-(4-(2-(4-(1-allyl-3-(4-(methylsulfonyl)phenyl)ur...)Show SMILES CC(C)(C)NS(=O)(=O)c1cc(C(=O)N2CCC(CCN3CCC(CC3)N(CC=C)C(=O)Nc3ccc(cc3)S(C)(=O)=O)(CC2)c2cccc(F)c2)c(Cl)cc1F Show InChI InChI=1S/C40H50ClF2N5O6S2/c1-6-19-48(38(50)44-30-10-12-32(13-11-30)55(5,51)52)31-14-20-46(21-15-31)22-16-40(28-8-7-9-29(42)25-28)17-23-47(24-18-40)37(49)33-26-36(35(43)27-34(33)41)56(53,54)45-39(2,3)4/h6-13,25-27,31,45H,1,14-24H2,2-5H3,(H,44,50) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infection |
Bioorg Med Chem Lett 20: 7397-400 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.033
BindingDB Entry DOI: 10.7270/Q27081P6 |
More data for this
Ligand-Target Pair | |