Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C motif chemokine 5
(Homo sapiens (Human)) | BDBM50329234
((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(1-(is...)Show SMILES CC(C)S(=O)(=O)N1CCC(CC1)C(CCN1C[C@H]2CN(C[C@H]2C1)C(=O)c1c(C)ncnc1C)c1ccccc1 |r| Show InChI InChI=1S/C30H43N5O3S/c1-21(2)39(37,38)35-14-10-25(11-15-35)28(24-8-6-5-7-9-24)12-13-33-16-26-18-34(19-27(26)17-33)30(36)29-22(3)31-20-32-23(29)4/h5-9,20-21,25-28H,10-19H2,1-4H3/t26-,27+,28? | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto
Curated by ChEMBL
| Assay Description
Inhibition of RANTES |
Bioorg Med Chem Lett 20: 6802-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.118
BindingDB Entry DOI: 10.7270/Q29G5N1F |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50329234
((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(1-(is...)Show SMILES CC(C)S(=O)(=O)N1CCC(CC1)C(CCN1C[C@H]2CN(C[C@H]2C1)C(=O)c1c(C)ncnc1C)c1ccccc1 |r| Show InChI InChI=1S/C30H43N5O3S/c1-21(2)39(37,38)35-14-10-25(11-15-35)28(24-8-6-5-7-9-24)12-13-33-16-26-18-34(19-27(26)17-33)30(36)29-22(3)31-20-32-23(29)4/h5-9,20-21,25-28H,10-19H2,1-4H3/t26-,27+,28? | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto
Curated by ChEMBL
| Assay Description
Inhibition of CCR5 by cell-cell fusion inhibition assay |
Bioorg Med Chem Lett 20: 6802-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.118
BindingDB Entry DOI: 10.7270/Q29G5N1F |
More data for this
Ligand-Target Pair | |