Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 495.5 BDBM50248267

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50248267 ((+/-)-N-((1S)-3-(4-(3-isopropyl-5-methyl-4H-1,2,4-...) Show SMILES CC(C)c1nnc(C)n1C1CCN(CC1)C(C)C[C@H](NC(=O)COCC(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C25H36F3N5O2/c1-17(2)24-31-30-19(4)33(24)21-10-12-32(13-11-21)18(3)14-22(20-8-6-5-7-9-20)29-23(34)15-35-16-25(26,27)28/h5-9,17-18,21-22H,10-16H2,1-4H3,(H,29,34)/t18?,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52.8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...				Bioorg Med Chem Lett 19: 1499-503 (2009) Article DOI: 10.1016/j.bmcl.2009.01.008 BindingDB Entry DOI: 10.7270/Q2PN96JF
					More data for this Ligand-Target Pair