Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 536.4 BDBM50359474

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50359474 (CHEMBL1926875) Show SMILES CC(CCNC(=O)c1c(Cl)cncc1Cl)N1CCC(CC1)N(Cc1ccccc1)c1ccc(cc1)C#N Show InChI InChI=1S/C29H31Cl2N5O/c1-21(11-14-34-29(37)28-26(30)18-33-19-27(28)31)35-15-12-25(13-16-35)36(20-23-5-3-2-4-6-23)24-9-7-22(17-32)8-10-24/h2-10,18-19,21,25H,11-16,20H2,1H3,(H,34,37)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity against human CCR5 assessed as inhibition of HIV1 gp120-induced cell-cell fusion between human HeLa P4/R5 cells and CHO-tat10 cel...				Bioorg Med Chem Lett 21: 6950-4 (2011) Article DOI: 10.1016/j.bmcl.2011.09.133 BindingDB Entry DOI: 10.7270/Q2GM87RZ
					More data for this Ligand-Target Pair