Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50143755
((4-Diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-...)Show SMILES CC1(CCN(CC1)C(=O)c1c[nH]c2ccccc12)N1CCC(CC1)N(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H36N4O/c1-32(18-22-34(23-19-32)31(37)29-24-33-30-15-9-8-14-28(29)30)35-20-16-27(17-21-35)36(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-15,24,27,33H,16-23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Antagonistic activity against human C-C chemokine receptor type 5. |
J Med Chem 47: 1939-55 (2004)
Article DOI: 10.1021/jm031046g
BindingDB Entry DOI: 10.7270/Q2V12478 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50143755
((4-Diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-...)Show SMILES CC1(CCN(CC1)C(=O)c1c[nH]c2ccccc12)N1CCC(CC1)N(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H36N4O/c1-32(18-22-34(23-19-32)31(37)29-24-33-30-15-9-8-14-28(29)30)35-20-16-27(17-21-35)36(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-15,24,27,33H,16-23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 283 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Rises in intracellular [Ca2+] levels by using [Ca2+] sensitive Fluo4 dye in C-C chemokine receptor type 5-transfected CHO cells. |
J Med Chem 47: 1939-55 (2004)
Article DOI: 10.1021/jm031046g
BindingDB Entry DOI: 10.7270/Q2V12478 |
More data for this
Ligand-Target Pair | |