Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50185970
(CHEMBL207301 | methyl 4-({1-[3-((3,4-Dichloropheny...)Show SMILES COC(=O)c1ccc(CC2CCN(CCCN(C(=O)C3CCN(CC3)S(C)(=O)=O)c3ccc(Cl)c(Cl)c3)CC2)cc1 Show InChI InChI=1S/C30H39Cl2N3O5S/c1-40-30(37)25-6-4-22(5-7-25)20-23-10-16-33(17-11-23)14-3-15-35(26-8-9-27(31)28(32)21-26)29(36)24-12-18-34(19-13-24)41(2,38)39/h4-9,21,23-24H,3,10-20H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
| Assay Description
Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cells |
J Med Chem 49: 2784-93 (2006)
Article DOI: 10.1021/jm051034q
BindingDB Entry DOI: 10.7270/Q2ZK5G8F |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50185970
(CHEMBL207301 | methyl 4-({1-[3-((3,4-Dichloropheny...)Show SMILES COC(=O)c1ccc(CC2CCN(CCCN(C(=O)C3CCN(CC3)S(C)(=O)=O)c3ccc(Cl)c(Cl)c3)CC2)cc1 Show InChI InChI=1S/C30H39Cl2N3O5S/c1-40-30(37)25-6-4-22(5-7-25)20-23-10-16-33(17-11-23)14-3-15-35(26-8-9-27(31)28(32)21-26)29(36)24-12-18-34(19-13-24)41(2,38)39/h4-9,21,23-24H,3,10-20H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
| Assay Description
Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5 |
J Med Chem 49: 2784-93 (2006)
Article DOI: 10.1021/jm051034q
BindingDB Entry DOI: 10.7270/Q2ZK5G8F |
More data for this
Ligand-Target Pair | |