Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50331648
(CHEMBL1288914 | methyl 4-((3-allyl-3-(1-(2-(1-(5-(...)Show SMILES COC(=O)c1ccc(CNC(=O)N(CC=C)C2CCN(CCC3(CCN(CC3)C(=O)c3cc(c(F)cc3Cl)S(=O)(=O)NC(C)(C)C)c3cccc(F)c3)CC2)cc1 Show InChI InChI=1S/C42H52ClF2N5O6S/c1-6-19-50(40(53)46-28-29-10-12-30(13-11-29)39(52)56-5)33-14-20-48(21-15-33)22-16-42(31-8-7-9-32(44)25-31)17-23-49(24-18-42)38(51)34-26-37(36(45)27-35(34)43)57(54,55)47-41(2,3)4/h6-13,25-27,33,47H,1,14-24,28H2,2-5H3,(H,46,53) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infection |
Bioorg Med Chem Lett 20: 7397-400 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.033
BindingDB Entry DOI: 10.7270/Q27081P6 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50331648
(CHEMBL1288914 | methyl 4-((3-allyl-3-(1-(2-(1-(5-(...)Show SMILES COC(=O)c1ccc(CNC(=O)N(CC=C)C2CCN(CCC3(CCN(CC3)C(=O)c3cc(c(F)cc3Cl)S(=O)(=O)NC(C)(C)C)c3cccc(F)c3)CC2)cc1 Show InChI InChI=1S/C42H52ClF2N5O6S/c1-6-19-50(40(53)46-28-29-10-12-30(13-11-29)39(52)56-5)33-14-20-48(21-15-33)22-16-42(31-8-7-9-32(44)25-31)17-23-49(24-18-42)38(51)34-26-37(36(45)27-35(34)43)57(54,55)47-41(2,3)4/h6-13,25-27,33,47H,1,14-24,28H2,2-5H3,(H,46,53) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infection |
Bioorg Med Chem Lett 20: 7397-400 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.033
BindingDB Entry DOI: 10.7270/Q27081P6 |
More data for this
Ligand-Target Pair | |