Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 620.4 BDBM50359469

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50359469 (CHEMBL1926882) Show SMILES COc1cccc(CN(C2CCN(CC2)C(C)CCNC(=O)c2c(Cl)cncc2Cl)c2ccc(Br)cc2)c1 Show InChI InChI=1S/C29H33BrCl2N4O2/c1-20(10-13-34-29(37)28-26(31)17-33-18-27(28)32)35-14-11-24(12-15-35)36(23-8-6-22(30)7-9-23)19-21-4-3-5-25(16-21)38-2/h3-9,16-18,20,24H,10-15,19H2,1-2H3,(H,34,37)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	387	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Antagonist activity against human CCR5 assessed as inhibition of HIV1 gp120-induced cell-cell fusion between human HeLa P4/R5 cells and CHO-tat10 cel...				Bioorg Med Chem Lett 21: 6950-4 (2011) Article DOI: 10.1016/j.bmcl.2011.09.133 BindingDB Entry DOI: 10.7270/Q2GM87RZ
					More data for this Ligand-Target Pair