Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 445.5 BDBM50276292

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50276292 (CHEMBL471218 | N-benzyl-N-(1-(1-(2,6-dimethylbenzo...) Show SMILES Cc1cccc(C)c1C(=O)N1CCC(CC1)N1CC(C1)N(Cc1ccccc1)C(=O)C1CC1 Show InChI InChI=1S/C28H35N3O2/c1-20-7-6-8-21(2)26(20)28(33)29-15-13-24(14-16-29)30-18-25(19-30)31(27(32)23-11-12-23)17-22-9-4-3-5-10-22/h3-10,23-25H,11-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...				Bioorg Med Chem Lett 19: 1084-8 (2009) Article DOI: 10.1016/j.bmcl.2009.01.012 BindingDB Entry DOI: 10.7270/Q2W095SG
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